NO952018L - Substituerte 3-(aminoalkylamino)-1,2-benzisoksazoler og beslektede forbindelser - Google Patents
Substituerte 3-(aminoalkylamino)-1,2-benzisoksazoler og beslektede forbindelserInfo
- Publication number
- NO952018L NO952018L NO952018A NO952018A NO952018L NO 952018 L NO952018 L NO 952018L NO 952018 A NO952018 A NO 952018A NO 952018 A NO952018 A NO 952018A NO 952018 L NO952018 L NO 952018L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- benzisoxazoles
- aminoalkylamino
- substituted
- related compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98002192A | 1992-11-23 | 1992-11-23 | |
US08/150,301 US5494908A (en) | 1992-11-23 | 1993-11-12 | Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds |
PCT/US1993/011416 WO1994012495A1 (en) | 1992-11-23 | 1993-11-22 | Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
NO952018D0 NO952018D0 (no) | 1995-05-22 |
NO952018L true NO952018L (no) | 1995-05-22 |
NO304980B1 NO304980B1 (no) | 1999-03-15 |
Family
ID=26847521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO952018A NO304980B1 (no) | 1992-11-23 | 1995-05-22 | Substituerte 3-(aminoalkylamino)-1,2-benzisoksazoler og beslektede forbindelser, farmas°ytiske preparater inneholdende dem og deres anvendelse for fremstilling av legemidler |
Country Status (14)
Country | Link |
---|---|
US (2) | US6046203A (no) |
EP (1) | EP0669920B1 (no) |
JP (1) | JP3462501B2 (no) |
AT (1) | ATE232529T1 (no) |
AU (1) | AU690529B2 (no) |
CA (1) | CA2149918A1 (no) |
DE (1) | DE69332691T2 (no) |
DK (1) | DK0669920T3 (no) |
ES (1) | ES2187518T3 (no) |
FI (1) | FI952481A (no) |
MX (1) | MX9307332A (no) |
NO (1) | NO304980B1 (no) |
NZ (1) | NZ258747A (no) |
PT (1) | PT669920E (no) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5494908A (en) * | 1992-11-23 | 1996-02-27 | Hoechst-Roussel Pharmaceutical Incorporated | Substituted 3-(aminoalkylamino)-1,2-benzisoxazoles and related compounds |
DE60109148T2 (de) * | 2000-04-28 | 2006-01-05 | Acadia Pharmaceuticals Inc., San Diego | Muscarinrezeptoren |
BRPI0518693A2 (pt) * | 2004-11-29 | 2008-12-02 | Warner Lambert Co | pirazol [3,4-b]piridinas e indazàis terapÊuticos, bem como composiÇço farmacÊutica e uso dos mesmos |
DE102005038947A1 (de) * | 2005-05-18 | 2006-11-30 | Grünenthal GmbH | Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln |
KR20120123089A (ko) * | 2010-02-16 | 2012-11-07 | 화이자 인코포레이티드 | 5-HT₄ 수용체의 부분 효능제인 (R)-4-((4-((4-(테트라히드로푸란-3-일옥시)벤조[d]이속사졸-3-일옥시)메틸)피페리딘-1-일)메틸)테트라히드로-2H-피란-4-올 |
JP6014155B2 (ja) | 2011-10-31 | 2016-10-25 | ゼノン・ファーマシューティカルズ・インコーポレイテッドXenon Pharmaceuticals Inc. | ビアリールエーテルスルホンアミドおよび治療剤としてのそれらの使用 |
KR20140091022A (ko) | 2011-10-31 | 2014-07-18 | 제논 파마슈티칼스 인크. | 벤젠술폰아미드 화합물 및 치료제로서의 그의 용도 |
MX2014014234A (es) | 2012-05-22 | 2015-05-07 | Genentech Inc | Benzamidas n-sustituidas y su uso en el tratamiento del dolor. |
CA2878478A1 (en) | 2012-07-06 | 2014-01-09 | Genentech, Inc. | N-substituted benzamides and methods of use thereof |
WO2014153037A1 (en) | 2013-03-14 | 2014-09-25 | Genentech, Inc. | Substituted triazolopyridines and methods of use thereof |
RU2015143834A (ru) * | 2013-03-15 | 2017-04-24 | Дженентек, Инк. | Замещенные бензоксазолы и способы их применения |
CN105492430B (zh) * | 2013-03-15 | 2017-10-10 | 基因泰克公司 | 取代的苯并噁唑及其使用方法 |
EP3074377B1 (en) | 2013-11-27 | 2018-10-17 | Genentech, Inc. | Substituted benzamides and methods of use thereof |
CN106715418A (zh) | 2014-07-07 | 2017-05-24 | 基因泰克公司 | 治疗化合物及其使用方法 |
MX2017014715A (es) | 2015-05-22 | 2018-03-16 | Genentech Inc | Benzamidas sustituidas y metodos para utilizarlas. |
JP2018526371A (ja) | 2015-08-27 | 2018-09-13 | ジェネンテック, インコーポレイテッド | 治療化合物及びその使用方法 |
CA2999769A1 (en) | 2015-09-28 | 2017-04-06 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
MA43304A (fr) | 2015-11-25 | 2018-10-03 | Genentech Inc | Benzamides substitués utiles en tant que bloqueurs de canaux sodiques |
EP3854782A1 (en) | 2016-03-30 | 2021-07-28 | Genentech, Inc. | Substituted benzamides and methods of use thereof |
SG11201903348UA (en) | 2016-10-17 | 2019-05-30 | Genentech Inc | Therapeutic compounds and methods of use thereof |
WO2018175707A1 (en) | 2017-03-24 | 2018-09-27 | Genentech, Inc. | 4-piperidin-n-(pyrimidin-4-yl)chroman-7-sulfonamide derivatives as sodium channel inhibitors |
US11028075B2 (en) | 2018-02-26 | 2021-06-08 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
US10947251B2 (en) | 2018-03-30 | 2021-03-16 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
EP3789383B9 (en) | 2018-04-27 | 2024-02-28 | Osaka University | Inhibitors of the trpc3 or trpc6 channel |
JP2021070688A (ja) * | 2019-10-24 | 2021-05-06 | 国立大学法人大阪大学 | 難聴の予防および/または治療用医薬組成物 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3381617D1 (de) * | 1982-03-17 | 1990-07-05 | Asahi Chemical Ind | Indazol-derivate. |
US4590196A (en) * | 1984-08-23 | 1986-05-20 | Bristol-Myers Company | Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives |
EP0302423A3 (en) * | 1987-08-07 | 1991-01-09 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments |
US5134236A (en) * | 1987-08-07 | 1992-07-28 | Hoechst-Roussel Pharmaceuticals Incorporated | Phenylhydrazones as intermediates 1-phenyl-3-(1-piperazenyl)-1H-indazoles |
US4999356A (en) * | 1987-08-07 | 1991-03-12 | Hoechst-Roussel Pharmaceuticals, Inc. | 1-phenyl-3-(1-piperazinyl)-1H-indazoles |
US5364866A (en) * | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
US4954503A (en) * | 1989-09-11 | 1990-09-04 | Hoechst-Roussel Pharmaceuticals, Inc. | 3-(1-substituted-4-piperazinyl)-1H-indazoles |
FR2654104B1 (fr) * | 1989-11-07 | 1992-01-03 | Adir | Nouveaux derives du 1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
US5147881A (en) * | 1990-11-14 | 1992-09-15 | Pfizer Inc | 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents |
BR9205811A (pt) * | 1991-03-28 | 1994-06-28 | Pfizer | Derivados heterociclicos de aminas ciclicas |
-
1993
- 1993-11-22 DK DK94902374T patent/DK0669920T3/da active
- 1993-11-22 JP JP51335294A patent/JP3462501B2/ja not_active Expired - Fee Related
- 1993-11-22 PT PT94902374T patent/PT669920E/pt unknown
- 1993-11-22 NZ NZ258747A patent/NZ258747A/en unknown
- 1993-11-22 CA CA002149918A patent/CA2149918A1/en not_active Abandoned
- 1993-11-22 AU AU56765/94A patent/AU690529B2/en not_active Ceased
- 1993-11-22 EP EP94902374A patent/EP0669920B1/en not_active Expired - Lifetime
- 1993-11-22 ES ES94902374T patent/ES2187518T3/es not_active Expired - Lifetime
- 1993-11-22 AT AT94902374T patent/ATE232529T1/de not_active IP Right Cessation
- 1993-11-22 DE DE69332691T patent/DE69332691T2/de not_active Expired - Fee Related
- 1993-11-23 MX MX9307332A patent/MX9307332A/es not_active Application Discontinuation
-
1995
- 1995-05-22 FI FI952481A patent/FI952481A/fi not_active IP Right Cessation
- 1995-05-22 NO NO952018A patent/NO304980B1/no not_active IP Right Cessation
- 1995-06-06 US US08/471,197 patent/US6046203A/en not_active Expired - Lifetime
- 1995-06-06 US US08/470,520 patent/US5580982A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69332691D1 (de) | 2003-03-20 |
DK0669920T3 (da) | 2003-05-26 |
AU5676594A (en) | 1994-06-22 |
DE69332691T2 (de) | 2003-12-18 |
ES2187518T3 (es) | 2003-06-16 |
US5580982A (en) | 1996-12-03 |
NO952018D0 (no) | 1995-05-22 |
JP3462501B2 (ja) | 2003-11-05 |
ATE232529T1 (de) | 2003-02-15 |
EP0669920B1 (en) | 2003-02-12 |
FI952481A0 (fi) | 1995-05-22 |
PT669920E (pt) | 2003-06-30 |
AU690529B2 (en) | 1998-04-30 |
JPH08506094A (ja) | 1996-07-02 |
FI952481A (fi) | 1995-05-22 |
EP0669920A4 (en) | 1995-10-25 |
MX9307332A (es) | 1994-07-29 |
NZ258747A (en) | 1997-02-24 |
EP0669920A1 (en) | 1995-09-06 |
NO304980B1 (no) | 1999-03-15 |
US6046203A (en) | 2000-04-04 |
CA2149918A1 (en) | 1994-06-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN MAY 2001 |