NO176695C - Fremgangsmåte for fremstilling av et smaksmaskert preparat av cefuroksim aksetil - Google Patents

Fremgangsmåte for fremstilling av et smaksmaskert preparat av cefuroksim aksetil

Info

Publication number
NO176695C
NO176695C NO882123A NO882123A NO176695C NO 176695 C NO176695 C NO 176695C NO 882123 A NO882123 A NO 882123A NO 882123 A NO882123 A NO 882123A NO 176695 C NO176695 C NO 176695C
Authority
NO
Norway
Prior art keywords
flavor
preparing
cefuroxime axetil
masked
preparation
Prior art date
Application number
NO882123A
Other languages
English (en)
Other versions
NO176695B (no
NO882123D0 (no
NO882123L (no
Inventor
Michael Bernhard James
Leonard Godfrey Elliott
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26292243&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO176695(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878711432A external-priority patent/GB8711432D0/en
Priority claimed from GB888802926A external-priority patent/GB8802926D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO882123D0 publication Critical patent/NO882123D0/no
Publication of NO882123L publication Critical patent/NO882123L/no
Publication of NO176695B publication Critical patent/NO176695B/no
Publication of NO176695C publication Critical patent/NO176695C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
NO882123A 1987-05-14 1988-05-13 Fremgangsmåte for fremstilling av et smaksmaskert preparat av cefuroksim aksetil NO176695C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878711432A GB8711432D0 (en) 1987-05-14 1987-05-14 Pharmaceutical composition
GB888802926A GB8802926D0 (en) 1988-02-09 1988-02-09 Pharmaceutical composition

Publications (4)

Publication Number Publication Date
NO882123D0 NO882123D0 (no) 1988-05-13
NO882123L NO882123L (no) 1988-11-15
NO176695B NO176695B (no) 1995-02-06
NO176695C true NO176695C (no) 1995-05-16

Family

ID=26292243

Family Applications (1)

Application Number Title Priority Date Filing Date
NO882123A NO176695C (no) 1987-05-14 1988-05-13 Fremgangsmåte for fremstilling av et smaksmaskert preparat av cefuroksim aksetil

Country Status (38)

Country Link
US (1) US4865851A (no)
JP (1) JPH0778023B2 (no)
KR (1) KR950009097B1 (no)
CN (1) CN1054508C (no)
AT (1) AT393794B (no)
AU (1) AU607996B2 (no)
BE (1) BE1000956A5 (no)
CA (1) CA1328405C (no)
CH (1) CH675357A5 (no)
CY (1) CY1600A (no)
CZ (1) CZ280884B6 (no)
DE (1) DE3816464C3 (no)
DK (1) DK175593B1 (no)
ES (1) ES2009915A6 (no)
FI (1) FI90825C (no)
FR (1) FR2615101B1 (no)
GB (1) GB2204792B (no)
GR (1) GR1000357B (no)
HK (1) HK106191A (no)
HU (1) HU200927B (no)
IE (1) IE61693B1 (no)
IL (1) IL86359A (no)
IT (1) IT1219941B (no)
MY (1) MY103525A (no)
NL (1) NL193682C (no)
NO (1) NO176695C (no)
NZ (1) NZ224598A (no)
PH (1) PH26015A (no)
PL (1) PL272429A1 (no)
PT (1) PT87474B (no)
RU (1) RU1837876C (no)
SA (1) SA91120129B1 (no)
SE (2) SE466047B (no)
SG (1) SG51491G (no)
SK (1) SK277898B6 (no)
UA (1) UA12335A (no)
YU (1) YU46640B (no)
ZW (1) ZW5988A1 (no)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
JP2681373B2 (ja) * 1988-07-18 1997-11-26 塩野義製薬株式会社 徐放性製剤の製造法
US5356644A (en) * 1989-01-25 1994-10-18 Pfizer Inc. Low calorie fat substitute
US5674504A (en) * 1989-07-12 1997-10-07 L'oreal Cosmetic composition in the form of an aqueous gel containing in suspension spheroids of a non-hydrophilic, lipoidal substance
FR2649608B1 (fr) * 1989-07-12 1991-10-11 Oreal Composition cosmetique sous forme d'un gel aqueux contenant en suspension des spheroides d'une substance lipidique solide non hydrophile
FR2660554B1 (fr) * 1990-04-05 1992-07-03 Oreal Composition cosmetique ou dermo-pharmaceutique aqueuse contenant en suspension des spherouides hydrates d'une substance lipidique hydrophile.
AU8913491A (en) * 1990-11-30 1992-06-25 Yamanouchi Pharmaceutical Co., Ltd. Quick release coated preparation
WO1992021328A1 (en) * 1991-05-28 1992-12-10 Affinity Biotech, Inc. Chewable drug-delivery composition
US5380535A (en) * 1991-05-28 1995-01-10 Geyer; Robert P. Chewable drug-delivery compositions and methods for preparing the same
DE4200821A1 (de) * 1992-01-15 1993-07-22 Bayer Ag Geschmacksmaskierte pharmazeutische mittel
CA2143439A1 (en) * 1992-09-03 1994-03-17 Seang H. Yiv Taste-masking pharmaceutical compostiions and methods for making the same
JPH08510989A (ja) * 1992-10-16 1996-11-19 グラクソ、グループ、リミテッド ラニチジン組成物
WO1994012157A1 (en) * 1992-11-30 1994-06-09 Kv Pharmaceutical Company Tastemasked pharmaceutical materials
IT1264020B (it) * 1993-01-28 1996-09-09 Recordati Chem Pharm Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi
WO1994025006A1 (en) * 1993-04-26 1994-11-10 Affinity Biotech, Inc. Taste-masking pharmaceutical compositions and methods for making the same
US7060293B1 (en) * 1994-05-25 2006-06-13 Purdue Pharma Powder-layered oral dosage forms
US5728403A (en) * 1994-10-05 1998-03-17 The Board Of Regents Of The University Of Nebraska Coating technology for taste masking orally administered bitter drugs
BE1009257A3 (nl) * 1995-03-21 1997-01-07 Universiteit Gent Lab Voor Far Farmaceutische matrix.
GB9702799D0 (en) * 1997-02-12 1997-04-02 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms
US6242019B1 (en) 1997-08-14 2001-06-05 Warner-Lambert Company Taste modified hard confectionery compositions containing functional ingredients
CA2209868C (en) * 1997-08-15 2001-08-14 Bernard Charles Sherman Pharmaceutical compositions comprising cefuroxime axetil
IN186539B (no) * 1997-09-29 2001-09-29 Ranbaxy Lab Ltd
EP1037607B1 (en) * 1997-12-08 2004-02-25 ALTANA Pharma AG Novel suppository form comprising an acid-labile active compound
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
US20020009478A1 (en) * 1998-08-24 2002-01-24 Douglas Joseph Dobrozsi Oral liquid mucoadhesive compositions
AT413647B (de) 1998-11-26 2006-04-15 Sandoz Ag Verwendung eines copolymerisats aus 1-vinyl-2-pyrrolidon und vinylacetat zur herstellung von cefuroximaxetil-hältigen tabletten
EP2275141A1 (en) * 1999-03-17 2011-01-19 Daiichi Pharmaceutical Co., Ltd. Tastemasked pharmaceutical compositions
IN190831B (no) * 1999-03-19 2003-08-23 Ranbaxy Lab Ltd
WO2000059467A1 (fr) 1999-04-06 2000-10-12 Laboratoires Des Produits Ethiques Ethypharm Suspension pharmaceutique buvable d'ibuprofene
IN191239B (no) 1999-06-11 2003-10-11 Ranbaxy Lab Ltd
KR100342943B1 (ko) * 1999-08-04 2002-07-02 민경윤 비결정질 세푸록심 악세틸 고형분산체, 이의 제조 방법 및 이를 포함하는 경구투여용 조성물
AT500063A1 (de) * 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
JP2002138034A (ja) * 2000-10-27 2002-05-14 Kyoto Pharmaceutical Industries Ltd 苦味マスキングチュアブル錠およびその製造方法
AU2001230490A1 (en) * 2000-12-01 2002-06-11 Arun Shriniwas Gosavi Pharmaceutical formulation
JP4310605B2 (ja) * 2001-05-25 2009-08-12 大塚製薬株式会社 医薬用組成物
US6589955B2 (en) 2001-06-20 2003-07-08 Bristol-Myers Squibb Company Pediatric formulation of gatifloxacin
WO2003020241A2 (en) * 2001-09-05 2003-03-13 Vectura Limited Functional powders for oral delivery
ES2201932B2 (es) * 2001-11-23 2005-03-16 Glaxo Group Limited Composicion farmaceutica.
KR20030055571A (ko) * 2001-12-27 2003-07-04 주식회사 백텍 카르복실 메틸 세룰로오스를 이용한 서방성마이크로스피어 제제의 개발
WO2003075829A2 (en) * 2002-03-08 2003-09-18 M/S. Ind-Swift Limited Tasteless directly compressible fast-dissolving complexes and pharmaceutical formulations thereof
WO2003077842A2 (en) * 2002-03-12 2003-09-25 Bristol-Myers Squibb Company Palatable oral suspension and method
KR100523082B1 (ko) * 2002-09-11 2005-10-20 (주)다산메디켐 쓴 맛이 은폐된 세푸록심악세틸 제제의 제약조성물 및 그의 제조방법
US20060018972A1 (en) * 2002-11-26 2006-01-26 Upm Pharmaceuticals, Inc. Aqueous sustained-release drug delivery system for highly water-soluble electrolytic drugs
US20100092562A1 (en) * 2002-11-26 2010-04-15 Hollenbeck R Gary Sustained-release drug delivery compositions and methods
FR2848855B1 (fr) * 2002-12-23 2005-02-11 Aventis Pharma Sa Compositions pour administration orale de principes actifs necessitant un masquage du gout
US20040146553A1 (en) * 2002-12-23 2004-07-29 Aventis Pharma S.A. Compositions for oral administration of active principles requiring masking of taste
WO2005002540A2 (en) * 2003-07-01 2005-01-13 Ranbaxy Laboratories Limited Dry powder pharmaceutical suspension compositions of cefuroxime axetil
US20050084540A1 (en) * 2003-10-17 2005-04-21 Indranil Nandi Taste masking antibiotic composition
US8168228B2 (en) * 2003-10-17 2012-05-01 Sandoz Ag Antibiotic clarithromycin micropellet compositions
US7943585B2 (en) 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
US20090175952A1 (en) * 2004-01-09 2009-07-09 Jong Soo Woo Cefuroxime axetil granule and process for the preparation thereof
KR100801589B1 (ko) 2004-01-09 2008-02-05 한미약품 주식회사 세푸록심 악세틸 과립 및 이의 제조방법
WO2005094791A1 (en) * 2004-03-19 2005-10-13 Eczacibasi Ozgun Kimyasal Urunler San. Tic. A.S. Preparation of lipid coated cefuroxime axetil
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
US7727576B2 (en) * 2004-04-16 2010-06-01 Hewlett-Packard Development Company, L.P. System and a method for producing layered oral dosage forms
GB2419094A (en) 2004-10-12 2006-04-19 Sandoz Ag Pharmaceutical composition of unpleasnt tasing active substances
EP1845937A1 (en) * 2004-12-10 2007-10-24 Of Scientific & Industrial Research Council Pharmaceutical composition for improving palatability of drugs and process for preparation thereof
US7378109B2 (en) * 2004-12-23 2008-05-27 Council Of Scientific And Industrial Research Pharmaceutical composition for improving palatability of drugs and process for preparation thereof
DE102005019458A1 (de) * 2005-04-25 2006-10-26 Grünenthal GmbH Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
US20060292225A1 (en) * 2005-06-24 2006-12-28 Felix Arthur M Water soluble analgesic formulations and methods for production
CN100402035C (zh) * 2005-07-07 2008-07-16 石药集团中奇制药技术（石家庄）有限公司 一种微囊化头孢呋辛酯的药物组合物
WO2007063552A1 (en) * 2005-12-02 2007-06-07 Lupin Limited Stable taste masked formulations of cephalosporins
US20070128268A1 (en) * 2005-12-07 2007-06-07 Herwig Jennewein Pharmaceutical compositions comprising an antibiotic
DE102005062270A1 (de) * 2005-12-24 2007-06-28 Bayer Technology Services Gmbh Geschmacksmaskierung von Pulvern
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
US8110226B2 (en) 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
FR2959130A1 (fr) 2010-04-21 2011-10-28 Sanofi Aventis Procede de preparation de compositions pharmaceutiques destinees a l'administration par voie orale comprenant un ou plusieurs principes actifs et les compositions les comprenant.
WO2012143492A1 (en) * 2011-04-20 2012-10-26 Dsm Ip Assets B.V. Beadlets comprising carotenoids
WO2013024373A1 (en) 2011-08-12 2013-02-21 Dhanuka Laboratories Ltd. Pharmaceutical composition comprising cefuroxime
CN102440960A (zh) * 2011-09-01 2012-05-09 山东鲁抗医药股份有限公司 一种头孢呋辛酯干混悬剂药物组合物及其制备方法
WO2013038323A1 (en) * 2011-09-13 2013-03-21 Unimark Remedies Ltd. Taste masked pharmaceutical compositions of cefuroxime axetil
RU2603906C2 (ru) 2011-10-14 2016-12-10 ДСМ АйПи АССЕТС Б.В. Система нового покрытия
EP2825159B1 (en) 2012-03-15 2022-06-22 Boehringer Ingelheim Vetmedica GmbH Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof
CN103330683B (zh) * 2013-06-26 2014-12-03 神威药业集团有限公司 一种富马酸替诺福韦酯细粒剂
PL3021832T3 (pl) 2013-07-19 2021-08-23 Boehringer Ingelheim Vetmedica Gmbh Konserwowana ciekła wodna kompozycja farmaceutyczna zawierająca eteryfikowane pochodne cyklodekstryny
CN103610680B (zh) * 2013-11-07 2015-12-30 国药集团致君（深圳）制药有限公司 一种头孢呋辛酯组合物及其制备方法
BR112016011111B1 (pt) 2013-12-04 2022-11-16 Boehringer Ingelheim Vetmedica Gmbh Composições farmacêuticas aprimoradas de pimobendan
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
KR101899773B1 (ko) * 2017-03-07 2018-09-18 일동제약(주) 베시포비르 디피복실 또는 이의 약제학적 허용되는 염 함유 과립, 상기 과립을 포함하는 약제학적 조성물 및 이의 제조 방법
CN107233317B (zh) * 2017-05-25 2020-07-24 北京万鹏朗格医药科技有限公司 一种含精氨酸布洛芬的药物组合物及其制备方法
KR102044676B1 (ko) * 2019-03-27 2019-11-14 주식회사 씨트리 생체적합성 고분자 기반 아픽사반 함유 미립구의 제조방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921883A (en) * 1957-05-03 1960-01-19 Smith Kline French Lab Novel coating material for medicaments
GB922697A (en) * 1958-12-01 1963-04-03 Merck & Co Inc Coated vitamin preparations and a process for making them
US3080293A (en) * 1960-08-02 1963-03-05 Hoffmann La Roche Process of making pleasant-tasting niacinamide beadlets
GB1323161A (en) * 1970-02-16 1973-07-11 Wyeth John & Brother Ltd Penicillin composition
DE2115116C3 (de) * 1970-03-27 1982-04-15 Sankyo Co., Ltd., Tokyo Gleitmittel und Verfahren zu dessen Herstellung
GB1413186A (en) * 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
JPS51112564A (en) * 1975-03-28 1976-10-05 Ajinomoto Kk Production of nutritive matearial for diet food
DE2950977A1 (de) * 1978-12-22 1980-07-10 Donald E Panoz Neue galenische zubereitungsform fuer die orale verabreichung von medikamenten mit programmierter besetzung, sowie verfahren zu ihrer herstellung
JPS6029682B2 (ja) * 1980-07-11 1985-07-12 山之内製薬株式会社 苦味のない製剤用組成物およびその製造法
US4302440B1 (en) * 1980-07-31 1986-08-05 Easily-swallowed, powder-free and gastric-disintegrable aspirin tablet thinly-coated with hydroxypropyl methylcellulose and aqueous spray-coating preparation thereof
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
US4533542A (en) * 1983-08-22 1985-08-06 Eli Lilly And Company Pharmaceutical compositions for storage in plastic containers and process therefor
US4713245A (en) * 1984-06-04 1987-12-15 Mitsui Toatsu Chemicals, Incorporated Granule containing physiologically-active substance, method for preparing same and use thereof
US4764375A (en) * 1985-09-11 1988-08-16 Kv Pharmaceutical Company Sachet drug delivery system
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition

Also Published As

Publication number Publication date
AU1615788A (en) 1988-11-17
GB2204792B (en) 1991-01-23
SG51491G (en) 1991-08-23
JPS63303928A (ja) 1988-12-12
CH675357A5 (no) 1990-09-28
NO176695B (no) 1995-02-06
HK106191A (en) 1992-01-03
RU1837876C (ru) 1993-08-30
CN1054508C (zh) 2000-07-19
DE3816464C3 (de) 2001-12-20
PH26015A (en) 1992-01-29
NZ224598A (en) 1989-08-29
IE881452L (en) 1988-11-14
DE3816464A1 (de) 1988-11-24
KR950009097B1 (ko) 1995-08-14
YU46640B (sh) 1994-01-20
CA1328405C (en) 1994-04-12
SK277898B6 (en) 1995-07-11
CZ280884B6 (cs) 1996-04-17
ZW5988A1 (en) 1990-04-04
PT87474B (pt) 1992-09-30
YU92788A (en) 1990-06-30
DK263288A (da) 1988-11-15
IT8847962A0 (it) 1988-05-13
AT393794B (de) 1991-12-10
DK175593B1 (da) 2004-12-13
NO882123D0 (no) 1988-05-13
SA91120129B1 (ar) 2004-08-29
MY103525A (en) 1993-07-31
SE8801813D0 (sv) 1988-05-13
NL8801236A (nl) 1988-12-01
DE3816464C2 (de) 1996-08-29
IL86359A0 (en) 1988-11-15
BE1000956A5 (fr) 1989-05-23
IL86359A (en) 1992-11-15
AU607996B2 (en) 1991-03-21
GB2204792A (en) 1988-11-23
PL272429A1 (en) 1989-02-20
FI882253A0 (fi) 1988-05-13
CN88102851A (zh) 1988-12-21
ES2009915A6 (es) 1989-10-16
NL193682B (nl) 2000-03-01
HUT47022A (en) 1989-01-30
FI882253A (fi) 1988-11-15
IE61693B1 (en) 1994-11-16
CY1600A (en) 1992-04-03
FR2615101A1 (fr) 1988-11-18
HU200927B (en) 1990-09-28
PT87474A (pt) 1989-05-31
IT1219941B (it) 1990-05-24
ATA125988A (de) 1991-06-15
GR1000357B (el) 1992-06-25
SE8801813L (sv) 1988-11-15
CS403391A3 (en) 1992-08-12
FI90825B (fi) 1993-12-31
NO882123L (no) 1988-11-15
GR880100317A (en) 1989-02-23
KR880013560A (ko) 1988-12-21
UA12335A (uk) 1996-12-25
JPH0778023B2 (ja) 1995-08-23
DK263288D0 (da) 1988-05-13
US4865851A (en) 1989-09-12
SE466047B (sv) 1991-12-09
FR2615101B1 (fr) 1992-02-07
GB8811378D0 (en) 1988-06-15
NL193682C (nl) 2000-07-04
FI90825C (fi) 1994-04-11

Similar Documents

Publication Publication Date Title
NO176695C (no) Fremgangsmåte for fremstilling av et smaksmaskert preparat av cefuroksim aksetil
NO179357C (no) Fremgangsmåte for fremstilling av et farmasöytisk preparat med forlenget frigivelse
NO173312C (no) Fremgangsm}te for fremstilling av n{ringsmidler
FI880941A (fi) Menetelmä terapeuttisesti käyttökelpoisten piperatsinyyli-heterosyklisten yhdisteiden valmistamiseksi
PT86934A (pt) Process for the preparation of a thiazepine compound
PT88481A (pt) Process for the preparation of a new cephem compound
PT86875A (pt) Process for the preparation of phenylcarbamate
NO882103D0 (no) Fremgangsmaate for fremstilling av et farmasoeytisk preparat
PT86687A (pt) Process for the preparation of novel polyamine derivatives
PT86631A (pt) Process for the preparation of a novel crystalline form of potassium clavulanate
FI93215C (fi) Menetelmä terapeuttisesti käyttökelpoisten aminoalkoksifenyylijohdannaisten valmistamiseksi
NO175963C (no) Fremgangsmåte for fremstilling av et vannopplöselig antibiotisk preparat
PT87503A (pt) Process for the preparation of new cathecolamine by products
FI92064C (fi) Menetelmä terapeuttisesti käyttökelpoisten N-bentsopyranyylilaktaamien valmistamiseksi
NO171792C (no) Fremgangsmaate for fremstilling av en friradikal-addisjonspolymer
FI880842A0 (fi) Menetelmä kiteisen kefeemisulfaatin valmistamiseksi
PT88545A (pt) Process for the manufacture of benzimidazoline-2-oxo-1-carboxylic acid derivative compounds
FI884473A (fi) Menetelmä terapeuttisesti käyttökelpoisten fenoksialkyylipyrokatekolijohdannaisten valmistamiseksi
NO307093B1 (no) Fremgangsmåte for fremstilling av et baryttkjelestensinhiberende preparat
PT86938A (pt) Process for the preparation of a macrocyclic compound
NO176915C (no) Fremgangsmåte for fremstilling av et hirudin-derivat
RO94561A7 (ro) Procedeu pentru prepararea unui derivat de acid prostatrienoic
FI893434A (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten sykloalkyylitiatsolijohdannaisten valmistamiseksi
PT86899A (pt) Process for preparing 27-halo derivatives of ll-f28249 compounds
GB2020281A (en) Process of preparing a solid preparation of a penicillin derivative

Legal Events

Date Code Title Description
MK1K Patent expired