PT86631A - Process for the preparation of a novel crystalline form of potassium clavulanate - Google Patents
Process for the preparation of a novel crystalline form of potassium clavulanateInfo
- Publication number
- PT86631A PT86631A PT86631A PT8663188A PT86631A PT 86631 A PT86631 A PT 86631A PT 86631 A PT86631 A PT 86631A PT 8663188 A PT8663188 A PT 8663188A PT 86631 A PT86631 A PT 86631A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- crystalline form
- novel crystalline
- potassium clavulanate
- clavulanate
- Prior art date
Links
- ABVRVIZBZKUTMK-JSYANWSFSA-M potassium clavulanate Chemical compound [K+].[O-]C(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 ABVRVIZBZKUTMK-JSYANWSFSA-M 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US878187A | 1987-01-29 | 1987-01-29 | |
| US7494487A | 1987-07-17 | 1987-07-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT86631A true PT86631A (pt) | 1988-02-01 |
| PT86631B PT86631B (pt) | 1992-01-31 |
Family
ID=26678616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT86631A PT86631B (pt) | 1987-01-29 | 1988-01-27 | Processo para a preparacao de uma nova forma cristalina de clavulanato de potassio |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0277008B1 (pt) |
| JP (2) | JP2648321B2 (pt) |
| KR (1) | KR960004535B1 (pt) |
| AT (1) | AT399154B (pt) |
| AU (1) | AU620538B2 (pt) |
| BE (1) | BE1000734A3 (pt) |
| CA (1) | CA1326486C (pt) |
| CH (1) | CH677671A5 (pt) |
| DE (1) | DE3853962T2 (pt) |
| DK (1) | DK175709B1 (pt) |
| ES (2) | ES2074048T3 (pt) |
| FR (1) | FR2610196B1 (pt) |
| GB (1) | GB2200355B (pt) |
| GR (1) | GR1000035B (pt) |
| IE (1) | IE880217L (pt) |
| IT (1) | IT1227072B (pt) |
| LU (1) | LU87123A1 (pt) |
| NZ (1) | NZ223316A (pt) |
| PT (1) | PT86631B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2435859A (en) * | 1945-06-06 | 1948-02-10 | John E Whitman | Garment hanger |
| US2494711A (en) * | 1946-06-28 | 1950-01-17 | Kusher Hyman | Garment hanger |
| US3474943A (en) * | 1967-02-21 | 1969-10-28 | Frank Mcbain | Skirt hanger |
| SE7805391L (sv) * | 1978-05-11 | 1979-11-12 | Karner & Co Ab | Kledhengare |
| GB9205071D0 (en) * | 1992-03-09 | 1992-04-22 | Wellcome Found | Therapeutic nucleosides |
| AT400033B (de) | 1992-03-10 | 1995-09-25 | Biochemie Gmbh | Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben |
| SE9401169L (sv) * | 1994-04-08 | 1995-10-09 | Corimed Gmbh | Förfarande för framställning av ett antibekteriellt aktivt ämne samt användning därav |
| GB9426261D0 (en) | 1994-12-24 | 1995-02-22 | Spurcourt Ltd | Clavulanic acid salts |
| GB9515809D0 (en) * | 1995-08-02 | 1995-10-04 | Smithkline Beecham Plc | Process |
| AT403375B (de) * | 1995-11-15 | 1998-01-26 | Biochemie Gmbh | Verfahren zur fällung von alkalisalzen der clavulansäure |
| ZA975198B (en) * | 1996-06-13 | 1997-12-15 | Smithkline Beecham Corp | Improved process for preparing potassium clavulanate. |
| DE60008508T9 (de) * | 1999-04-01 | 2012-06-14 | Dsm Ip Assets B.V. | Agglomerate durch kristallisation |
| DK1284978T4 (da) | 2000-05-13 | 2009-01-05 | Smithkline Beecham Plc | Fremgangsmåde til oprensning af et salt af clavulansyre |
| JP4622855B2 (ja) * | 2003-06-10 | 2011-02-02 | 大正製薬株式会社 | 放射球状晶析物およびその製造方法並びにこれを利用するドライパウダー製剤 |
| CN100384853C (zh) * | 2004-05-10 | 2008-04-30 | 河北张药股份有限公司 | 替卡西林钠的合成方法 |
| KR102459377B1 (ko) * | 2022-03-18 | 2022-10-28 | 주식회사 에이치투뉴트리션 | 무알콜 단백질 맥주의 제조방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1508977A (en) * | 1974-04-20 | 1978-04-26 | Beecham Group Ltd | Beta-lactam antibiotic from streptomyces clavuligerus |
| GB1504425A (en) * | 1975-08-20 | 1978-03-22 | Beecham Group Ltd | Salts of clavulanic acid |
| GB2003863B (en) * | 1977-09-01 | 1982-03-31 | Beecham Group Ltd | Chemical process |
| DE3063683D1 (en) | 1979-08-24 | 1983-07-14 | Beecham Group Plc | Amine salt of clavulanic acid, its preparation and use |
| US4454069A (en) * | 1979-08-24 | 1984-06-12 | Beecham Group Limited | Clavulanic acid salts and their preparation from the tertiary butyl amine salt |
| EP0080862B1 (en) * | 1981-12-02 | 1985-09-25 | Beecham Group Plc | Pharmaceutical formulation comprising beta-lactam antibiotics |
| FR2586561B1 (fr) * | 1985-09-05 | 1988-05-20 | Rhone Poulenc Sante | Procede de preparation d'agglomerats spheriques de paracetamol et produits obtenus |
-
1988
- 1988-01-27 DE DE3853962T patent/DE3853962T2/de not_active Expired - Lifetime
- 1988-01-27 IT IT8847572A patent/IT1227072B/it active
- 1988-01-27 GB GB8801765A patent/GB2200355B/en not_active Expired - Lifetime
- 1988-01-27 ES ES88300704T patent/ES2074048T3/es not_active Expired - Lifetime
- 1988-01-27 EP EP88300704A patent/EP0277008B1/en not_active Expired - Lifetime
- 1988-01-27 ES ES8800226A patent/ES2008418A6/es not_active Expired
- 1988-01-27 CA CA000557422A patent/CA1326486C/en not_active Expired - Lifetime
- 1988-01-27 DK DK198800404A patent/DK175709B1/da not_active IP Right Cessation
- 1988-01-27 GR GR880100031A patent/GR1000035B/el not_active IP Right Cessation
- 1988-01-27 IE IE880217A patent/IE880217L/xx not_active IP Right Cessation
- 1988-01-27 AT AT0016388A patent/AT399154B/de not_active IP Right Cessation
- 1988-01-27 PT PT86631A patent/PT86631B/pt unknown
- 1988-01-27 NZ NZ223316A patent/NZ223316A/xx unknown
- 1988-01-28 BE BE8800098A patent/BE1000734A3/fr not_active IP Right Cessation
- 1988-01-28 KR KR1019880000765A patent/KR960004535B1/ko not_active Expired - Lifetime
- 1988-01-28 AU AU10927/88A patent/AU620538B2/en not_active Expired
- 1988-01-28 CH CH299/88A patent/CH677671A5/de not_active IP Right Cessation
- 1988-01-29 JP JP63021144A patent/JP2648321B2/ja not_active Expired - Lifetime
- 1988-01-29 FR FR888801033A patent/FR2610196B1/fr not_active Expired - Lifetime
- 1988-01-29 LU LU87123A patent/LU87123A1/fr unknown
-
1996
- 1996-12-03 JP JP8339027A patent/JP2716966B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0277008B1 (en) | 1995-06-14 |
| AU620538B2 (en) | 1992-02-20 |
| FR2610196B1 (fr) | 1991-06-28 |
| DE3853962T2 (de) | 1996-02-08 |
| GR1000035B (el) | 1990-03-12 |
| EP0277008A1 (en) | 1988-08-03 |
| LU87123A1 (fr) | 1988-05-03 |
| ATA16388A (de) | 1994-08-15 |
| ES2008418A6 (es) | 1989-07-16 |
| DK40488A (da) | 1988-07-30 |
| GB2200355B (en) | 1990-08-01 |
| DK40488D0 (da) | 1988-01-27 |
| GB8801765D0 (en) | 1988-02-24 |
| JP2716966B2 (ja) | 1998-02-18 |
| KR890002166A (ko) | 1989-04-08 |
| FR2610196A1 (fr) | 1988-08-05 |
| AU1092788A (en) | 1988-08-04 |
| NZ223316A (en) | 1989-10-27 |
| CH677671A5 (pt) | 1991-06-14 |
| DK175709B1 (da) | 2005-01-31 |
| GR880100031A (en) | 1988-12-16 |
| BE1000734A3 (fr) | 1989-03-21 |
| PT86631B (pt) | 1992-01-31 |
| IT8847572A0 (it) | 1988-06-27 |
| CA1326486C (en) | 1994-01-25 |
| GB2200355A (en) | 1988-08-03 |
| JPH09169771A (ja) | 1997-06-30 |
| IE880217L (en) | 1988-07-29 |
| JP2648321B2 (ja) | 1997-08-27 |
| ES2074048T3 (es) | 1995-09-01 |
| AT399154B (de) | 1995-03-27 |
| JPS63270687A (ja) | 1988-11-08 |
| IT1227072B (it) | 1991-03-14 |
| DE3853962D1 (de) | 1995-07-20 |
| KR960004535B1 (ko) | 1996-04-06 |
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