NO169438C - Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrazolforbindelser - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrazolforbindelser

Info

Publication number
NO169438C
NO169438C NO880809A NO880809A NO169438C NO 169438 C NO169438 C NO 169438C NO 880809 A NO880809 A NO 880809A NO 880809 A NO880809 A NO 880809A NO 169438 C NO169438 C NO 169438C
Authority
NO
Norway
Prior art keywords
tetrazolic
compounds
preparation
therapeutic active
analogy procedure
Prior art date
Application number
NO880809A
Other languages
English (en)
Norwegian (no)
Other versions
NO880809L (no
NO880809D0 (no
NO169438B (no
Inventor
John J Wright
Sing-Yuen Sit
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO880809D0 publication Critical patent/NO880809D0/no
Publication of NO880809L publication Critical patent/NO880809L/no
Priority to NO913089A priority Critical patent/NO913089D0/no
Publication of NO169438B publication Critical patent/NO169438B/no
Publication of NO169438C publication Critical patent/NO169438C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO880809A 1987-02-25 1988-02-24 Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrazolforbindelser NO169438C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO913089A NO913089D0 (no) 1987-02-25 1991-08-08 Fremgangsmaate for fremstilling av tetrazolforbindelser.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1854287A 1987-02-25 1987-02-25
US07/151,513 US4897490A (en) 1987-02-25 1988-02-18 Antihypercholesterolemic tetrazole compounds

Publications (4)

Publication Number Publication Date
NO880809D0 NO880809D0 (no) 1988-02-24
NO880809L NO880809L (no) 1988-08-26
NO169438B NO169438B (no) 1992-03-16
NO169438C true NO169438C (no) 1992-06-24

Family

ID=26691223

Family Applications (1)

Application Number Title Priority Date Filing Date
NO880809A NO169438C (no) 1987-02-25 1988-02-24 Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrazolforbindelser

Country Status (31)

Country Link
US (1) US4897490A (fr)
JP (1) JP2603324B2 (fr)
KR (1) KR960001203B1 (fr)
CN (1) CN1026110C (fr)
AT (1) AT395589B (fr)
AU (1) AU1395088A (fr)
BE (1) BE1002116A3 (fr)
CA (1) CA1328268C (fr)
CH (1) CH676848A5 (fr)
CS (1) CS271481B2 (fr)
DE (1) DE3805801C2 (fr)
DK (1) DK174822B1 (fr)
EG (1) EG18341A (fr)
ES (2) ES2010246A6 (fr)
FI (1) FI96601C (fr)
FR (1) FR2612924B1 (fr)
GR (1) GR1000472B (fr)
HU (3) HU204516B (fr)
IE (1) IE61619B1 (fr)
IL (1) IL85529A (fr)
IT (1) IT1216751B (fr)
LU (1) LU87144A1 (fr)
MX (1) MX9202847A (fr)
MY (1) MY103214A (fr)
NL (1) NL8800465A (fr)
NO (1) NO169438C (fr)
NZ (1) NZ223620A (fr)
PT (1) PT86820B (fr)
SE (1) SE503618C2 (fr)
WO (1) WO1988006584A1 (fr)
YU (1) YU36388A (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3741509A1 (de) * 1987-12-08 1989-06-22 Hoechst Ag Verfahren zur herstellung optisch aktiver 3-desmethylmevalonsaeurederivate sowie zwischenprodukte
GB2244705B (en) * 1988-02-18 1992-07-15 Bristol Myers Co Preparation of antihypercholesterolemic tetrazole compounds and intermediates thereof
US4824959A (en) * 1988-02-18 1989-04-25 Bristol-Myers Company Intermediates for antihypercholesterolemic tetrazole compounds
US4870187A (en) * 1988-08-23 1989-09-26 Bristol-Myers Company Antihypercholesterolemic tetrazol-1-yl compounds
US5010205A (en) * 1988-08-23 1991-04-23 Bristol-Myers Company Antihypercholesterolemic tetrazol-1-yl intermediates
US4927944A (en) * 1988-08-25 1990-05-22 Bristol-Myers Company Antihypercholesterolemic nitrile compounds
FI94339C (fi) 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
US5413935A (en) * 1991-04-24 1995-05-09 E. R. Squibb & Sons, Inc. Process for selecting an enantiomer of a hydroxy lactone using pseudomonas lipase
US5134155A (en) * 1991-08-08 1992-07-28 Ortho Pharmaceutical Corporation Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-coA reductase inhibitors
US5986095A (en) * 1992-01-06 1999-11-16 E.R. Squibb & Sons, Inc. Enantioselective preparation of halophenyl alcohols and acylates
US5278313A (en) * 1992-03-27 1994-01-11 E. R. Squibb & Sons, Inc. Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors
US5324662A (en) * 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters
US5284957A (en) * 1992-09-03 1994-02-08 Eli Lilly And Company Excitatory amino acid receptor antagonists
JPH06329679A (ja) * 1993-01-20 1994-11-29 Nissan Chem Ind Ltd 光学活性β−アミノアルコキシボラン錯体
CA2137049A1 (fr) * 1993-12-15 1995-06-16 John K. Thottathil Sels d'acides amines de composes antihypercholesterolemiques a base de tetrazole et leur methode de preparation
DE19714343A1 (de) 1997-04-08 1998-10-15 Bayer Ag Chromatographische Enantiomerentrennung von Lactonen
NZ504346A (en) * 1997-12-19 2001-11-30 Warner Lambert Exp Ltd Process for the synthesis of 1,3-diols characterised by either reconcentration step with either trialkylborane or dialkylalkoxyborane or a mixture of both trialkylborane and dialkylalkoxyborane
DE10216967A1 (de) * 2002-04-16 2003-11-13 Bayer Ag Verfahren zur Herstellung spezieller aromatischer Aldehyde
EP2178890A1 (fr) * 2007-07-12 2010-04-28 Teva Pharmaceutical Industries Ltd. Purification de l'intermédiaire de la rosuvastatine par évaporation en film mince et procédé chimique
KR101681041B1 (ko) 2015-07-15 2016-12-22 경북대학교병원 ＥＲＲγ 비활성화 리간드로서의 신규한 방향족 고리 화합물 유도체

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054666A (en) * 1973-03-23 1977-10-18 American Home Products Corporation Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives
US4160100A (en) * 1973-03-23 1979-07-03 American Home Products Corporation Oxamic acid derivatives
US4013647A (en) * 1976-03-23 1977-03-22 American Home Products Corporation Morpholine containing tetrazole-5-carboxamide derivatives
JPS53147073A (en) * 1977-05-24 1978-12-21 Sankyo Co Ltd Mevalonolactone derivatives
US4567289A (en) * 1979-08-17 1986-01-28 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
US4375475A (en) * 1979-08-17 1983-03-01 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
NZ194557A (en) * 1979-08-17 1984-09-28 Merck & Co Inc Substituted pyranone derivatives;dihydroxy acids therefrom;pharmaceutical compositions
EP0068038B1 (fr) * 1981-06-29 1985-09-25 Merck & Co. Inc. (+)-(4R.6S)-(E)-6-(2-(4'-fluoro-3,3',5-triméthyl-(1,1'-biphényl)-2-yle)éthenyl)-3,4,5,6-tétrahydro-4-hydroxy-2H-pyran-2-one, un procédé pour sa fabrication et une composition pharmaceutique la contenant
WO1983002131A1 (fr) * 1981-12-10 1983-06-23 Willy Bayer Moteur a combustion interne
WO1984002131A1 (fr) * 1982-11-22 1984-06-07 Sandoz Ag Produits analogues de mevalolactone et leurs derives, leurs procedes de production, compositions pharmaceutiques les contenant ainsi que leur utilisation en tant que produits pharmaceutiques
US4739073A (en) * 1983-11-04 1988-04-19 Sandoz Pharmaceuticals Corp. Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
ES8609193A1 (es) * 1983-01-24 1986-07-16 Sandoz Ag Procedimiento para preparar analogos de mevalonolactona y derivados de los mismos
CA1327360C (fr) * 1983-11-14 1994-03-01 William F. Hoffman Analogues oxo d'agents antihypercholesterolemiants ayant les caracteristiques de la mevinoline
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
KR890001651B1 (ko) * 1984-06-22 1989-05-12 산도즈 파마슈티칼스 코포레이션 메발로노락톤의 피라졸 동족체 및 이의 유도체의 제조방법
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
US4621099A (en) * 1985-09-23 1986-11-04 Usv Pharmaceutical Corporation Polyene compounds useful in the treatment of allergic responses
US4681893A (en) * 1986-05-30 1987-07-21 Warner-Lambert Company Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
US4678806A (en) * 1986-09-02 1987-07-07 Merck & Co., Inc. Prodrugs of antihypercholesterolemic compounds

Also Published As

Publication number Publication date
PT86820A (pt) 1989-02-28
BE1002116A3 (fr) 1990-07-10
ES2010246A6 (es) 1989-11-01
FR2612924A1 (fr) 1988-09-30
YU36388A (en) 1989-10-31
AT395589B (de) 1993-01-25
FI880869A0 (fi) 1988-02-24
NO880809L (no) 1988-08-26
AU1395088A (en) 1988-09-26
IE61619B1 (en) 1994-11-16
IE880501L (en) 1988-08-25
SE8800638L (sv) 1988-09-21
ES2026746A6 (es) 1992-05-01
FR2612924B1 (fr) 1991-01-11
IT8819525A0 (it) 1988-02-24
US4897490A (en) 1990-01-30
EG18341A (en) 1993-08-30
NZ223620A (en) 1991-07-26
CA1328268C (fr) 1994-04-05
DK97288A (da) 1988-08-26
JPH01502269A (ja) 1989-08-10
WO1988006584A1 (fr) 1988-09-07
HU203329B (en) 1991-07-29
KR880009947A (ko) 1988-10-06
CS118088A2 (en) 1989-08-14
HUT47259A (en) 1989-02-28
DE3805801A1 (de) 1988-09-08
FI96601B (fi) 1996-04-15
MX9202847A (es) 1992-06-30
CH676848A5 (fr) 1991-03-15
CN1026110C (zh) 1994-10-05
MY103214A (en) 1993-05-29
NO880809D0 (no) 1988-02-24
NO169438B (no) 1992-03-16
HU204038B (en) 1991-11-28
ATA46188A (de) 1992-06-15
IT1216751B (it) 1990-03-08
SE8800638D0 (sv) 1988-02-24
KR960001203B1 (ko) 1996-01-24
DK174822B1 (da) 2003-12-08
GR1000472B (el) 1992-07-30
FI96601C (fi) 1996-07-25
HU900669D0 (en) 1990-06-28
CN88100911A (zh) 1988-09-28
HU896737D0 (en) 1990-02-28
NL8800465A (nl) 1988-09-16
GR880100101A (en) 1988-12-16
DK97288D0 (da) 1988-02-24
SE503618C2 (sv) 1996-07-15
IL85529A0 (en) 1988-08-31
PT86820B (pt) 1995-03-01
LU87144A1 (fr) 1988-09-20
CS271481B2 (en) 1990-10-12
HU204516B (en) 1992-01-28
DE3805801C2 (de) 2001-03-01
JP2603324B2 (ja) 1997-04-23
FI880869A (fi) 1988-08-26
IL85529A (en) 1993-01-31

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Legal Events

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MK1K Patent expired