NO165027C - Analogifremgangsmaate for fremstilling av terapeutisk aktive propenyl-cefalosporinforbindelser. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive propenyl-cefalosporinforbindelser.

Info

Publication number
NO165027C
NO165027C NO840334A NO840334A NO165027C NO 165027 C NO165027 C NO 165027C NO 840334 A NO840334 A NO 840334A NO 840334 A NO840334 A NO 840334A NO 165027 C NO165027 C NO 165027C
Authority
NO
Norway
Prior art keywords
actival
cephalospor
propenyl
therapeutic
compounds
Prior art date
Application number
NO840334A
Other languages
English (en)
Norwegian (no)
Other versions
NO165027B (no
NO840334L (no
Inventor
Hideaki Hoshi
Yoshio Abe
Takayuki Naito
Jun Okumura
Shimpei Aburaki
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27040143&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO165027(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO840334L publication Critical patent/NO840334L/no
Priority to NO85850080A priority Critical patent/NO165028C/no
Priority to NO85854339A priority patent/NO165109C/no
Priority to NO864286A priority patent/NO165110C/no
Publication of NO165027B publication Critical patent/NO165027B/no
Publication of NO165027C publication Critical patent/NO165027C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO840334A 1983-01-28 1984-01-27 Analogifremgangsmaate for fremstilling av terapeutisk aktive propenyl-cefalosporinforbindelser. NO165027C (no)

Priority Applications (3)

Application Number Priority Date Filing Date Title
NO85850080A NO165028C (no) 1983-01-28 1985-01-08 Mellomprodukter for fremstilling av cefalosporinforbindelser.
NO85854339A NO165109C (no) 1983-01-28 1985-10-30 Cefalosporinforbindelse.
NO864286A NO165110C (no) 1983-01-28 1986-10-27 Cefalosporinforbindelse.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46183383A 1983-01-28 1983-01-28
US06/564,604 US4520022A (en) 1983-01-28 1983-12-28 Substituted vinyl cephalosporins

Publications (3)

Publication Number Publication Date
NO840334L NO840334L (no) 1984-07-30
NO165027B NO165027B (no) 1990-09-03
NO165027C true NO165027C (no) 1990-12-12

Family

ID=27040143

Family Applications (1)

Application Number Title Priority Date Filing Date
NO840334A NO165027C (no) 1983-01-28 1984-01-27 Analogifremgangsmaate for fremstilling av terapeutisk aktive propenyl-cefalosporinforbindelser.

Country Status (32)

Country Link
US (1) US4520022A (da)
AR (1) AR240824A1 (da)
AT (1) AT383351B (da)
BE (1) BE898778A (da)
CA (3) CA1233815A (da)
CH (1) CH661731A5 (da)
CY (1) CY1528A (da)
CZ (1) CZ280411B6 (da)
DD (2) DD222029A5 (da)
DE (1) DE3402642A1 (da)
DK (1) DK162052C (da)
ES (2) ES529171A0 (da)
FI (2) FI79540C (da)
FR (1) FR2540117B1 (da)
GB (1) GB2135305B (da)
GR (1) GR79791B (da)
HK (1) HK73690A (da)
HU (1) HU191990B (da)
IE (1) IE56784B1 (da)
IL (1) IL70773A (da)
IT (1) IT1218842B (da)
LU (1) LU85184A1 (da)
NL (1) NL190581C (da)
NO (1) NO165027C (da)
NZ (1) NZ206973A (da)
OA (1) OA07643A (da)
PT (1) PT78020B (da)
SE (2) SE458611B (da)
SK (1) SK278845B6 (da)
SU (1) SU1407400A3 (da)
YU (1) YU44393B (da)
ZW (1) ZW1184A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZM884A1 (en) * 1983-01-28 1984-10-22 Bristol Myers Co Substituted vinyl cephalosporins
GB8411954D0 (en) * 1984-05-10 1984-06-13 Glaxo Group Ltd Cephalosporin antibiotics
US4699979A (en) * 1985-04-22 1987-10-13 Bristol-Meyers Company 7-amino-3-propenylcephalosporanic acid and esters thereof
FR2580652B1 (fr) * 1985-04-22 1989-01-06 Bristol Myers Co Acide 7-amino-3-propenylcephalosporanique et ses esters
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
US4694079A (en) * 1985-07-29 1987-09-15 Bristol-Myers Company 3-propenyl cephalosporin solvates
US4619925A (en) * 1985-11-08 1986-10-28 Bristol-Myers Company 3-Propenyl cephalosporin derivatives
US4727070A (en) * 1985-11-25 1988-02-23 Bristol-Myers Company 3-Propenzl cephalosporin isomer separation process and derivative
US4870168A (en) * 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems
DE3734005A1 (de) * 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3734004A1 (de) * 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5128336A (en) * 1988-03-23 1992-07-07 Eli Lilly And Company 3-(substituted)-1-carba(dethia)-3-cephems
US5245027A (en) * 1989-11-21 1993-09-14 Bristol-Myers Squibb Company 3-fluorosulfonyloxyceph-3-em compounds
KR950700311A (ko) 1992-02-05 1995-01-16 게오르게스 그렐리니, 한스 루돌프하우스 3-세펨-4-카복실산 유도체의 정제방법(Process for the purification of a 3-cephem-4-carboxylic acid derivatives)
CN1649614A (zh) 2002-02-22 2005-08-03 新河药品股份有限公司 活性剂传递系统和保护及施用活性剂的方法
US7230097B2 (en) * 2003-03-10 2007-06-12 Lupin Ltd. Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid
WO2004110399A2 (en) * 2003-06-19 2004-12-23 Ranbaxy Laboratories Limited Solvates of cefprozil
EP1678186A4 (en) 2003-10-30 2007-04-25 Cj Corp PROCESS FOR THE PREPARATION OF CEPHEM DERIVATIVES
US20070072945A1 (en) * 2004-03-31 2007-03-29 Pohoreski Anton Sulphur-containing oils for controlling plant pathogens and stimulating nutrient uptake
EP1809638B1 (en) * 2004-11-01 2010-02-17 Hetero Drugs Limited A novel process for preparation of cefprozil intermediate
EP2209474A4 (en) 2007-10-09 2013-07-24 Sopharmia Inc BROAD SPECTRUM BETA-LACTAMASE INHIBITORS
TR201000689A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Sefprozil içeren katı dozaj formlar.
WO2013109201A1 (en) 2012-01-18 2013-07-25 Mahmut Bilgic Pharmaceutical compositions comprising cefprozil and clavulanic acid
WO2014165126A2 (en) 2013-03-12 2014-10-09 Sopharmia, Inc. Derivatized 3-styryl-cephalosporins

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507861A (en) * 1966-09-14 1970-04-21 Lilly Co Eli Certain 3-methyl-cephalosporin compounds
US3351596A (en) * 1966-09-21 1967-11-07 Lilly Co Eli 3-formyl cephalosporins
US3489750A (en) * 1967-09-05 1970-01-13 Bristol Myers Co 7-amino-cephalosporanic and decephalosporanic acid derivatives
US3485819A (en) * 1968-07-02 1969-12-23 Squibb & Sons Inc Alpha-amino-cyclohexadienylalkylene-penicillins and cephalosporins
US4107431A (en) * 1970-01-23 1978-08-15 Glaxo Laboratories Limited Δ3 -3-Vinyl or substituted vinyl-4-carboxy cephalosporins
US3994884A (en) * 1970-01-23 1976-11-30 Glaxo Laboratories Limited 3-Vinyl-7β-(2,2-disubstituted acetamido)-cephalosporins
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US3674784A (en) * 1970-07-27 1972-07-04 Lilly Co Eli 3-formyl cephalosporin sulfoxides
US4065620A (en) * 1971-06-14 1977-12-27 Eli Lilly And Company 3-(Substituted) vinyl cephalosporins
BE789817A (fr) 1971-10-07 1973-04-06 Glaxo Lab Ltd Perfectionnements aux composes de cephalosporine
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
GB1472174A (en) * 1973-09-22 1977-05-04 Beecham Group Ltd Dihydroxy amino cephalosporins
FR2264021A1 (en) * 1974-03-13 1975-10-10 Aries Robert Cephalosporanic acid antibiotics - from alpha amino phenyl acetic acids and phosphorus trihalide then a 7-amino cepheme
JPS5129492A (en) * 1974-09-04 1976-03-12 Sankyo Co Sefuarosuhorinjudotai no seiho
US4049806A (en) * 1975-08-15 1977-09-20 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US3983113A (en) * 1975-08-15 1976-09-28 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US4094978A (en) * 1976-07-29 1978-06-13 Syntex (U.S.A.) Inc. 3-propenyl derivatives of cephalosporin, compositions and their use
US4112087A (en) * 1976-11-04 1978-09-05 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials having a substituted propenyl group in the 3-position
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
FR2457297A1 (fr) * 1979-05-23 1980-12-19 Rhone Poulenc Ind Nouvelles vinyl-3 cephalosporines, et leur preparation
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof

Also Published As

Publication number Publication date
ZW1184A1 (en) 1984-08-29
NO165027B (no) 1990-09-03
PT78020B (en) 1986-06-02
SE8400419D0 (sv) 1984-01-27
BE898778A (fr) 1984-07-27
IE840026L (en) 1984-07-28
SK61684A3 (en) 1998-03-04
OA07643A (fr) 1985-05-23
NZ206973A (en) 1987-03-06
GB8402255D0 (en) 1984-02-29
CA1233815A (en) 1988-03-08
ES535953A0 (es) 1985-10-01
GR79791B (da) 1984-10-31
FI79540B (fi) 1989-09-29
CY1528A (en) 1990-11-16
LU85184A1 (fr) 1984-10-24
FI79540C (fi) 1990-01-10
FR2540117A1 (fr) 1984-08-03
DK162052B (da) 1991-09-09
CZ280411B6 (cs) 1996-01-17
ES8505206A1 (es) 1985-05-16
DK35384A (da) 1984-07-29
CA1241948A (en) 1988-09-13
AT383351B (de) 1987-06-25
AU2357584A (en) 1984-08-02
IE56784B1 (en) 1991-12-18
CA1225084A (en) 1987-08-04
SE466204B (sv) 1992-01-13
SK278845B6 (sk) 1998-03-04
NL8400229A (nl) 1984-08-16
IL70773A0 (en) 1984-04-30
NL190581B (nl) 1993-12-01
IT1218842B (it) 1990-04-24
FI840300A (fi) 1984-07-29
DE3402642A1 (de) 1984-08-02
NL190581C (nl) 1994-05-02
DD222029A5 (de) 1985-05-08
US4520022A (en) 1985-05-28
SE8400419L (sv) 1984-07-29
DD228261A5 (de) 1985-10-09
NO840334L (no) 1984-07-30
IL70773A (en) 1988-09-30
DK162052C (da) 1992-02-10
CH661731A5 (de) 1987-08-14
GB2135305A (en) 1984-08-30
YU14084A (en) 1987-06-30
FI81356C (fi) 1990-10-10
DK35384D0 (da) 1984-01-26
HK73690A (en) 1990-09-28
AU566112B2 (en) 1987-10-08
DE3402642C2 (da) 1989-11-09
SE458611B (sv) 1989-04-17
PT78020A (en) 1984-02-01
GB2135305B (en) 1987-03-04
YU44393B (en) 1990-06-30
SU1407400A3 (ru) 1988-06-30
ES529171A0 (es) 1985-05-16
HU191990B (en) 1987-04-28
HUT34492A (en) 1985-03-28
FI840300A0 (fi) 1984-01-25
FI81356B (fi) 1990-06-29
SE8703153L (sv) 1987-08-13
FR2540117B1 (fr) 1987-03-20
IT8419346A0 (it) 1984-01-27
AR240824A2 (es) 1991-02-28
FI881929A0 (fi) 1988-04-25
AR240824A1 (es) 1991-02-28
SE8703153D0 (sv) 1987-08-13
ATA29984A (de) 1986-11-15
FI881929A (fi) 1988-04-25
ES8600310A1 (es) 1985-10-01

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