NO160203C - Analogifremgangsmaate for fremstilling av terapeutisk virksomme fenotiazin-forbindelser. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksomme fenotiazin-forbindelser.

Info

Publication number
NO160203C
NO160203C NO834424A NO834424A NO160203C NO 160203 C NO160203 C NO 160203C NO 834424 A NO834424 A NO 834424A NO 834424 A NO834424 A NO 834424A NO 160203 C NO160203 C NO 160203C
Authority
NO
Norway
Prior art keywords
phenotiazin
compounds
preparation
therapeutically effective
analogue procedure
Prior art date
Application number
NO834424A
Other languages
English (en)
Other versions
NO834424L (no
NO160203B (no
Inventor
Geoffrey George Coker
John William Addison Findlay
Harry Jefferson Leighton
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838318832A external-priority patent/GB8318832D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NO834424L publication Critical patent/NO834424L/no
Publication of NO160203B publication Critical patent/NO160203B/no
Publication of NO160203C publication Critical patent/NO160203C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18[b, e]-condensed with two six-membered rings
    • C07D279/20[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18[b, e]-condensed with two six-membered rings
    • C07D279/22[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO834424A 1982-12-02 1983-12-01 Analogifremgangsmaate for fremstilling av terapeutisk virksomme fenotiazin-forbindelser. NO160203C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8234398 1982-12-02
GB838318832A GB8318832D0 (en) 1983-07-12 1983-07-12 Chemical compounds

Publications (3)

Publication Number Publication Date
NO834424L NO834424L (no) 1984-06-04
NO160203B NO160203B (no) 1988-12-12
NO160203C true NO160203C (no) 1989-03-22

Family

ID=26284560

Family Applications (1)

Application Number Title Priority Date Filing Date
NO834424A NO160203C (no) 1982-12-02 1983-12-01 Analogifremgangsmaate for fremstilling av terapeutisk virksomme fenotiazin-forbindelser.

Country Status (22)

Country Link
EP (1) EP0117302B1 (no)
JP (1) JPH06767B2 (no)
KR (1) KR890000638B1 (no)
AU (1) AU572105B2 (no)
BG (2) BG50158A3 (no)
CA (1) CA1280749C (no)
DD (1) DD213922A5 (no)
DE (1) DE3381689D1 (no)
DK (1) DK551283A (no)
ES (7) ES8504752A1 (no)
FI (1) FI81788C (no)
GR (1) GR81958B (no)
HU (1) HU193274B (no)
IE (1) IE56998B1 (no)
IL (2) IL70359A (no)
MC (1) MC1562A1 (no)
NO (1) NO160203C (no)
NZ (1) NZ206458A (no)
PH (1) PH20433A (no)
PL (2) PL145778B1 (no)
PT (1) PT77766B (no)
YU (1) YU44758B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8413915D0 (en) * 1984-05-31 1984-07-04 Wellcome Found Phenothiazine compounds
JPS6256489A (ja) * 1985-09-04 1987-03-12 Sanwa Kagaku Kenkyusho:Kk 新規なピロリチジン化合物及びその塩、これらの製法並びにこれらを有効成分とする消化性潰瘍治療剤
US6333322B1 (en) 1996-03-13 2001-12-25 Eisai Co., Ltd. Nitrogen-containing tricyclic compounds and drugs containing the same
EP2229590B1 (en) 2007-12-10 2018-11-21 Ascensia Diabetes Care Holdings AG Process of making 3-phenylimino-3h-phenothiazine or 3-phenylimino-3h-phenoxazine mediator
US9187439B2 (en) 2011-09-21 2015-11-17 Inception Orion, Inc. Tricyclic compounds useful as neurogenic and neuroprotective agents
KR101646962B1 (ko) 2014-09-29 2016-08-10 한국과학기술연구원 CaM 저해활성을 가지는 페노싸이아진 유도체
US10035795B1 (en) 2017-04-06 2018-07-31 Korea Institute Of Science And Technology Phenothiazine derivatives having CaM inhibitory activity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2956996A (en) * 1960-10-18 Alkylated phenotfflazenecarboxamede
BE552557A (no) * 1955-11-15
BE554020A (no) * 1956-01-10
NL58901C (no) * 1957-02-07 1947-02-15
NL273878A (no) * 1961-01-24
US3112310A (en) * 1962-01-15 1963-11-26 Searle & Co 10-alkylaminoalkylphenothiazine-2-carboxamides

Also Published As

Publication number Publication date
CA1280749C (en) 1991-02-26
FI834401A (fi) 1984-06-03
KR840006996A (ko) 1984-12-04
BG50158A3 (en) 1992-05-15
DE3381689D1 (de) 1990-08-02
PH20433A (en) 1987-01-05
PT77766A (en) 1984-01-01
NO834424L (no) 1984-06-04
IL70359A0 (en) 1984-03-30
AU572105B2 (en) 1988-05-05
ES534356A0 (es) 1985-07-01
JPS59110684A (ja) 1984-06-26
ES8506675A1 (es) 1985-08-01
EP0117302A2 (en) 1984-09-05
NZ206458A (en) 1987-07-31
EP0117302A3 (en) 1984-10-17
PT77766B (en) 1986-05-30
AU2190083A (en) 1984-06-07
ES534355A0 (es) 1985-07-16
ES8506296A1 (es) 1985-07-01
ES8506676A1 (es) 1985-07-16
EP0117302B1 (en) 1990-06-27
IE832825L (en) 1984-06-02
FI81788C (fi) 1990-12-10
FI81788B (fi) 1990-08-31
YU234983A (en) 1986-02-28
YU44758B (en) 1991-02-28
ES8506674A1 (es) 1985-07-16
IE56998B1 (en) 1992-03-11
ES534357A0 (es) 1985-08-01
ES8506673A1 (es) 1985-07-16
DK551283A (da) 1984-06-03
ES527705A0 (es) 1985-04-16
KR890000638B1 (ko) 1989-03-22
DK551283D0 (da) 1983-12-01
HU193274B (en) 1987-09-28
GR81958B (no) 1984-12-12
ES8506672A1 (es) 1985-07-16
PL145778B1 (en) 1988-10-31
ES8504752A1 (es) 1985-04-16
BG47647A3 (en) 1990-08-15
DD213922A5 (de) 1984-09-26
FI834401A0 (fi) 1983-12-01
PL252163A1 (en) 1985-11-05
MC1562A1 (fr) 1984-11-12
ES534354A0 (es) 1985-07-16
PL252164A1 (en) 1985-11-19
ES534353A0 (es) 1985-07-16
JPH06767B2 (ja) 1994-01-05
NO160203B (no) 1988-12-12
IL70359A (en) 1988-05-31
ES534358A0 (es) 1985-07-16

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