SE8703153D0 - Mellanprodukter for framstellning av substituerade vinylcefalosporiner - Google Patents

Mellanprodukter for framstellning av substituerade vinylcefalosporiner

Info

Publication number
SE8703153D0
SE8703153D0 SE8703153A SE8703153A SE8703153D0 SE 8703153 D0 SE8703153 D0 SE 8703153D0 SE 8703153 A SE8703153 A SE 8703153A SE 8703153 A SE8703153 A SE 8703153A SE 8703153 D0 SE8703153 D0 SE 8703153D0
Authority
SE
Sweden
Prior art keywords
intermediates
preparation
substituted vinyl
cephalosporins
vinyl cephalosporins
Prior art date
Application number
SE8703153A
Other languages
English (en)
Other versions
SE8703153L (sv
SE466204B (sv
Inventor
H Hoshi
Y Abe
T Naito
J Okumura
S Aburaki
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27040143&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE8703153(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE8703153D0 publication Critical patent/SE8703153D0/sv
Publication of SE8703153L publication Critical patent/SE8703153L/sv
Publication of SE466204B publication Critical patent/SE466204B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/227-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8703153A 1983-01-28 1987-08-13 Mellanprodukter foer framstaellning av substituerade vinylcefalosporiner SE466204B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46183383A 1983-01-28 1983-01-28
US06/564,604 US4520022A (en) 1983-01-28 1983-12-28 Substituted vinyl cephalosporins

Publications (3)

Publication Number Publication Date
SE8703153D0 true SE8703153D0 (sv) 1987-08-13
SE8703153L SE8703153L (sv) 1987-08-13
SE466204B SE466204B (sv) 1992-01-13

Family

ID=27040143

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8400419A SE458611B (sv) 1983-01-28 1984-01-27 Substituerade vinylcefalosporiner, farmaceutisk komposition daerav samt foerfarande foer framstaellning daerav
SE8703153A SE466204B (sv) 1983-01-28 1987-08-13 Mellanprodukter foer framstaellning av substituerade vinylcefalosporiner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE8400419A SE458611B (sv) 1983-01-28 1984-01-27 Substituerade vinylcefalosporiner, farmaceutisk komposition daerav samt foerfarande foer framstaellning daerav

Country Status (32)

Country Link
US (1) US4520022A (sv)
AR (1) AR240824A1 (sv)
AT (1) AT383351B (sv)
BE (1) BE898778A (sv)
CA (3) CA1233815A (sv)
CH (1) CH661731A5 (sv)
CY (1) CY1528A (sv)
CZ (1) CZ280411B6 (sv)
DD (2) DD222029A5 (sv)
DE (1) DE3402642A1 (sv)
DK (1) DK162052C (sv)
ES (2) ES8505206A1 (sv)
FI (2) FI79540C (sv)
FR (1) FR2540117B1 (sv)
GB (1) GB2135305B (sv)
GR (1) GR79791B (sv)
HK (1) HK73690A (sv)
HU (1) HU191990B (sv)
IE (1) IE56784B1 (sv)
IL (1) IL70773A (sv)
IT (1) IT1218842B (sv)
LU (1) LU85184A1 (sv)
NL (1) NL190581C (sv)
NO (1) NO165027C (sv)
NZ (1) NZ206973A (sv)
OA (1) OA07643A (sv)
PT (1) PT78020B (sv)
SE (2) SE458611B (sv)
SK (1) SK278845B6 (sv)
SU (1) SU1407400A3 (sv)
YU (1) YU44393B (sv)
ZW (1) ZW1184A1 (sv)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA84584B (en) * 1983-01-28 1984-09-26 Bristol Myers Co Substituted vinyl cephalosporins
GB8411954D0 (en) * 1984-05-10 1984-06-13 Glaxo Group Ltd Cephalosporin antibiotics
FR2580652B1 (fr) * 1985-04-22 1989-01-06 Bristol Myers Co Acide 7-amino-3-propenylcephalosporanique et ses esters
US4699979A (en) * 1985-04-22 1987-10-13 Bristol-Meyers Company 7-amino-3-propenylcephalosporanic acid and esters thereof
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
US4694079A (en) * 1985-07-29 1987-09-15 Bristol-Myers Company 3-propenyl cephalosporin solvates
US4619925A (en) * 1985-11-08 1986-10-28 Bristol-Myers Company 3-Propenyl cephalosporin derivatives
US4727070A (en) * 1985-11-25 1988-02-23 Bristol-Myers Company 3-Propenzl cephalosporin isomer separation process and derivative
US4870168A (en) * 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems
DE3734004A1 (de) * 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3734005A1 (de) * 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5128336A (en) * 1988-03-23 1992-07-07 Eli Lilly And Company 3-(substituted)-1-carba(dethia)-3-cephems
US5245027A (en) * 1989-11-21 1993-09-14 Bristol-Myers Squibb Company 3-fluorosulfonyloxyceph-3-em compounds
WO1993016084A1 (en) 1992-02-05 1993-08-19 Biochemie Gesellschaft M.B.H. Process for the purification of a 3-cephem-4-carboxylic acid derivative
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
US7230097B2 (en) * 2003-03-10 2007-06-12 Lupin Ltd. Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid
EP1638520A2 (en) * 2003-06-19 2006-03-29 Ranbaxy Laboratories Limited Solvates of cefprozil
EP1678186A4 (en) 2003-10-30 2007-04-25 Cj Corp PROCESS FOR THE PREPARATION OF CEPHEM DERIVATIVES
US20070072945A1 (en) * 2004-03-31 2007-03-29 Pohoreski Anton Sulphur-containing oils for controlling plant pathogens and stimulating nutrient uptake
PL1809638T3 (pl) * 2004-11-01 2010-07-30 Hetero Drugs Ltd Nowy sposób wytwarzania związków pośrednich w syntezie cefprozilu
US8883772B2 (en) 2007-10-09 2014-11-11 Sopharmia, Inc. Broad spectrum beta-lactamase inhibitors
TR201000689A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Sefprozil içeren katı dozaj formlar.
WO2013109201A1 (en) 2012-01-18 2013-07-25 Mahmut Bilgic Pharmaceutical compositions comprising cefprozil and clavulanic acid
DK2968352T3 (da) 2013-03-12 2019-01-02 Gladius Pharmaceuticals Corp Derivatiserede 3-styryl-cephalosporiner

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507861A (en) * 1966-09-14 1970-04-21 Lilly Co Eli Certain 3-methyl-cephalosporin compounds
US3351596A (en) * 1966-09-21 1967-11-07 Lilly Co Eli 3-formyl cephalosporins
US3489752A (en) * 1967-09-05 1970-01-13 Bristol Myers Co 7-amino-cephalosporanic and decephalosporanic acid derivatives
US3485819A (en) * 1968-07-02 1969-12-23 Squibb & Sons Inc Alpha-amino-cyclohexadienylalkylene-penicillins and cephalosporins
US4107431A (en) * 1970-01-23 1978-08-15 Glaxo Laboratories Limited Δ3 -3-Vinyl or substituted vinyl-4-carboxy cephalosporins
US3994884A (en) * 1970-01-23 1976-11-30 Glaxo Laboratories Limited 3-Vinyl-7β-(2,2-disubstituted acetamido)-cephalosporins
US3769277A (en) 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US3674784A (en) * 1970-07-27 1972-07-04 Lilly Co Eli 3-formyl cephalosporin sulfoxides
US4065620A (en) * 1971-06-14 1977-12-27 Eli Lilly And Company 3-(Substituted) vinyl cephalosporins
BE789817A (fr) 1971-10-07 1973-04-06 Glaxo Lab Ltd Perfectionnements aux composes de cephalosporine
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
GB1472174A (en) * 1973-09-22 1977-05-04 Beecham Group Ltd Dihydroxy amino cephalosporins
FR2264021A1 (en) * 1974-03-13 1975-10-10 Aries Robert Cephalosporanic acid antibiotics - from alpha amino phenyl acetic acids and phosphorus trihalide then a 7-amino cepheme
JPS5129492A (en) * 1974-09-04 1976-03-12 Sankyo Co Sefuarosuhorinjudotai no seiho
US3983113A (en) * 1975-08-15 1976-09-28 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US4049806A (en) * 1975-08-15 1977-09-20 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US4094978A (en) * 1976-07-29 1978-06-13 Syntex (U.S.A.) Inc. 3-propenyl derivatives of cephalosporin, compositions and their use
US4112087A (en) * 1976-11-04 1978-09-05 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials having a substituted propenyl group in the 3-position
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
FR2457297A1 (fr) * 1979-05-23 1980-12-19 Rhone Poulenc Ind Nouvelles vinyl-3 cephalosporines, et leur preparation
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof

Also Published As

Publication number Publication date
FI881929A0 (fi) 1988-04-25
GB8402255D0 (en) 1984-02-29
FI881929A (fi) 1988-04-25
CZ280411B6 (cs) 1996-01-17
OA07643A (fr) 1985-05-23
ZW1184A1 (en) 1984-08-29
FI840300A (fi) 1984-07-29
FR2540117B1 (fr) 1987-03-20
NO840334L (no) 1984-07-30
DK35384D0 (da) 1984-01-26
NL8400229A (nl) 1984-08-16
NO165027B (no) 1990-09-03
PT78020B (en) 1986-06-02
DD228261A5 (de) 1985-10-09
IE56784B1 (en) 1991-12-18
SK61684A3 (en) 1998-03-04
SK278845B6 (sk) 1998-03-04
HU191990B (en) 1987-04-28
CY1528A (en) 1990-11-16
NO165027C (no) 1990-12-12
NZ206973A (en) 1987-03-06
DK162052B (da) 1991-09-09
DE3402642C2 (sv) 1989-11-09
FI79540C (sv) 1990-01-10
GB2135305A (en) 1984-08-30
AU2357584A (en) 1984-08-02
GB2135305B (en) 1987-03-04
HK73690A (en) 1990-09-28
ES529171A0 (es) 1985-05-16
DK35384A (da) 1984-07-29
DE3402642A1 (de) 1984-08-02
CA1225084A (en) 1987-08-04
FI840300A0 (fi) 1984-01-25
DD222029A5 (de) 1985-05-08
YU44393B (en) 1990-06-30
SE8703153L (sv) 1987-08-13
ES8505206A1 (es) 1985-05-16
IT1218842B (it) 1990-04-24
CH661731A5 (de) 1987-08-14
FI81356B (fi) 1990-06-29
HUT34492A (en) 1985-03-28
NL190581C (nl) 1994-05-02
BE898778A (fr) 1984-07-27
IL70773A0 (en) 1984-04-30
SE466204B (sv) 1992-01-13
CA1233815A (en) 1988-03-08
SU1407400A3 (ru) 1988-06-30
ES535953A0 (es) 1985-10-01
AR240824A1 (es) 1991-02-28
ATA29984A (de) 1986-11-15
FI81356C (sv) 1990-10-10
DK162052C (da) 1992-02-10
AR240824A2 (es) 1991-02-28
LU85184A1 (fr) 1984-10-24
CA1241948A (en) 1988-09-13
SE8400419L (sv) 1984-07-29
YU14084A (en) 1987-06-30
FI79540B (fi) 1989-09-29
US4520022A (en) 1985-05-28
SE8400419D0 (sv) 1984-01-27
FR2540117A1 (fr) 1984-08-03
ES8600310A1 (es) 1985-10-01
IL70773A (en) 1988-09-30
AU566112B2 (en) 1987-10-08
IT8419346A0 (it) 1984-01-27
NL190581B (nl) 1993-12-01
GR79791B (sv) 1984-10-31
PT78020A (en) 1984-02-01
IE840026L (en) 1984-07-28
AT383351B (de) 1987-06-25
SE458611B (sv) 1989-04-17

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