NL8901751A - Aerosolpreparaat met daarin nitroglycerine als werkzaam bestanddeel. - Google Patents

Aerosolpreparaat met daarin nitroglycerine als werkzaam bestanddeel. Download PDF

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Publication number
NL8901751A
NL8901751A NL8901751A NL8901751A NL8901751A NL 8901751 A NL8901751 A NL 8901751A NL 8901751 A NL8901751 A NL 8901751A NL 8901751 A NL8901751 A NL 8901751A NL 8901751 A NL8901751 A NL 8901751A
Authority
NL
Netherlands
Prior art keywords
component
nitroglycerin
glycol
preparation
solution
Prior art date
Application number
NL8901751A
Other languages
English (en)
Dutch (nl)
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of NL8901751A publication Critical patent/NL8901751A/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/30—Materials not provided for elsewhere for aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
NL8901751A 1988-07-08 1989-07-07 Aerosolpreparaat met daarin nitroglycerine als werkzaam bestanddeel. NL8901751A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU883585A HU199678B (en) 1988-07-08 1988-07-08 Process for producing aerosols containing nitroglicerol
HU358588 1988-07-08

Publications (1)

Publication Number Publication Date
NL8901751A true NL8901751A (nl) 1990-02-01

Family

ID=10964655

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8901751A NL8901751A (nl) 1988-07-08 1989-07-07 Aerosolpreparaat met daarin nitroglycerine als werkzaam bestanddeel.

Country Status (15)

Country Link
US (1) US5047230A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0651620B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT401613B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE1003253A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG89108A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH679371A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CY (1) CY1761A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3922650A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2633933B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2220949B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU199678B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1230742B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8901751A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU1837871C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UA (1) UA11237A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (47)

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DE4007705C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1990-03-10 1991-09-26 G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De
US5370862A (en) * 1990-06-13 1994-12-06 Schwarz Pharma Ag Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina
DE4018919C2 (de) * 1990-06-13 1994-08-25 Sanol Arznei Schwarz Gmbh Nitroglycerin-Spray
DE4026072A1 (de) * 1990-08-17 1992-02-20 Sanol Arznei Schwarz Gmbh Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray
DE4038203A1 (de) * 1990-11-30 1992-06-04 Kali Chemie Pharma Gmbh Pharmazeutische spray-zubereitungen mit coronaraktiven wirkstoffen
WO1995032715A1 (en) * 1994-05-27 1995-12-07 Neptune Pharmaceutical Corporation Nitric oxide donor composition and method for treatment of anal disorders
TW537903B (en) * 1995-06-27 2003-06-21 Boehringer Ingelheim Kg New stable pharmaceutical preparation for producing propellant gas-free aerosols
WO1997038662A2 (en) * 1996-04-12 1997-10-23 Flemington Pharmaceutical Corporation Buccal polar spray or capsule
US20030190286A1 (en) * 1997-10-01 2003-10-09 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma
US20030077228A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders
US20040136913A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing sumatriptan
US20030077227A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20040141923A1 (en) * 1997-10-01 2004-07-22 Dugger Harry A. Buccal, polar and non-polar spray containing alprazolam
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
US20030082107A1 (en) * 1997-10-01 2003-05-01 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer
US7632517B2 (en) * 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US20030095926A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract
US20030095927A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders
US20030077229A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
US20030185761A1 (en) * 1997-10-01 2003-10-02 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20040136915A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing atropine
US20040136914A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing ondansetron
EP2042161A1 (en) * 1997-10-01 2009-04-01 Novadel Pharma Inc. Propellant-free spray composition comprising anti-emetic agent
US20050002867A1 (en) * 1997-10-01 2005-01-06 Novadel Pharma Inc. Buccal, polar and non-polar sprays containing propofol
US20050281752A1 (en) * 1997-10-01 2005-12-22 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20050180923A1 (en) * 1997-10-01 2005-08-18 Dugger Harry A.Iii Buccal, polar and non-polar spray containing testosterone
US20050163719A1 (en) * 1997-10-01 2005-07-28 Dugger Harry A.Iii Buccal, polar and non-polar spray containing diazepam
US20090162300A1 (en) * 1997-10-01 2009-06-25 Dugger Iii Harry A Buccal, polar and non-polar spray containing alprazolam
US20050287075A1 (en) * 1997-10-01 2005-12-29 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating pain
DE19855097A1 (de) * 1998-11-28 2000-05-31 Wella Ag Pigmenthaltiges, verschäumbares Gel
WO2000047203A1 (en) * 1999-02-12 2000-08-17 Mqs, Inc. Formulation and system for intra-oral delivery of pharmaceutical agents
US10004684B2 (en) 2001-02-14 2018-06-26 Gw Pharma Limited Pharmaceutical formulations
GB0417675D0 (en) * 2004-08-09 2004-09-08 Futura Medical Dev Ltd Composition for promoting vascular smooth muscle relaxation
WO2006089082A2 (en) * 2005-02-17 2006-08-24 Velcera Pharmaceuticals Transmucosal administration of drug compositions for treating and preventing disorders in animals
GB0602224D0 (en) * 2006-02-03 2006-03-15 Futura Medical Dev Ltd Composition for promoting vascular smooth muscle relaxation
JP2009534387A (ja) * 2006-04-19 2009-09-24 ノヴァデル ファーマ インコーポレイテッド 安定な含水アルコール性経口噴霧調剤物および方法
JP2010513525A (ja) * 2006-12-22 2010-04-30 ノヴァデル ファーマ インコーポレイテッド 安定な抗嘔吐経口噴霧製剤および方法
MX2009012109A (es) * 2007-05-10 2010-02-22 Novadel Pharma Inc Composiciones contra el insomnio y metodos.
DE202008008079U1 (de) * 2008-06-16 2008-09-04 G. Pohl-Boskamp Gmbh & Co. Kg Pharmazeutische Zubereitung in Wasserdampf durchlässigen Behältern mit verbesserter Stabilität
EP2467128B1 (en) 2010-08-03 2016-04-13 G. Pohl-Boskamp GmbH & Co. KG Use of glyceryl trinitrate for treating traumatic edema
WO2012113563A1 (en) 2011-02-25 2012-08-30 G. Pohl-Boskamp Gmbh & Co. Kg Packaging of solid pharmaceutical preparations containing the active substance glyceryl trinitrate
US9248099B2 (en) 2012-05-31 2016-02-02 Desmoid Aktiengesellschaft Use of stabilized granules containing glyceryl trinitrate for arteriogenesis
ES2617494T3 (es) 2012-05-31 2017-06-19 G. Pohl-Boskamp Gmbh & Co. Kg Inducción de arteriogénesis con un donador de óxido nítrico tal como nitroglicerina
EP2878310B1 (en) * 2013-11-29 2017-01-11 G. Pohl-Boskamp GmbH & Co. KG Sprayable aqueous composition comprising glyceryl trinitrate
CN104984351B (zh) * 2015-06-15 2018-01-30 马应龙药业集团股份有限公司 一种硝酸甘油丙二醇溶液的制备方法
CN113125596B (zh) * 2021-04-07 2023-01-13 马应龙药业集团股份有限公司 一种高效液相色谱法测定硝酸甘油软膏中有关物质的方法
WO2025115019A1 (en) 2023-11-30 2025-06-05 Padagis Israel Pharmaceuticals Ltd. Stable nitroglycerin formulations

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE632504A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1962-05-24
US4001391A (en) * 1969-04-18 1977-01-04 Plough, Inc. Means for depositing aerosol sprays in buttery form
US4369173A (en) * 1974-11-27 1983-01-18 Wickhen Products, Inc. Antiperspirant compositions
IL61721A (en) * 1980-12-16 1984-03-30 Blank Izhak Nitroglycerin preparations
DE3109783C2 (de) * 1981-03-13 1987-04-02 Schwarz GmbH, 4019 Monheim Verfahren zur Herstellung einer ethanolfreien Nitroglycerinlösung mit einer Konzentration von etwa 1 mg Nitroglycerin/ml
US4440777A (en) * 1981-07-07 1984-04-03 Merck & Co., Inc. Use of eucalyptol for enhancing skin permeation of bio-affecting agents
DE3246081A1 (de) * 1982-12-13 1984-06-14 G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt Nitroglycerin-spray
EP0175671A1 (de) * 1984-08-23 1986-03-26 Kuhlemann & Co. Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung
US4885173A (en) * 1985-05-01 1989-12-05 University Of Utah Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
DE3613187A1 (de) * 1986-04-18 1987-10-22 Mack Chem Pharm Verwendung einer carbonsaeure in zur topischen anwendung bestimmten pharmazeutischen zubereitungen
JPH0645538B2 (ja) * 1987-09-30 1994-06-15 日本化薬株式会社 ニトログリセリンスプレー剤
DE4018919C2 (de) * 1990-06-13 1994-08-25 Sanol Arznei Schwarz Gmbh Nitroglycerin-Spray

Also Published As

Publication number Publication date
BG89108A (bg) 1993-12-24
DE3922650A1 (de) 1990-01-11
DE3922650C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-03-04
UA11237A (uk) 1996-12-25
FR2633933B1 (fr) 1994-07-22
US5047230A (en) 1991-09-10
JPH02142726A (ja) 1990-05-31
FR2633933A1 (fr) 1990-01-12
GB2220949A (en) 1990-01-24
IT1230742B (it) 1991-10-29
AT401613B (de) 1996-10-25
ATA165489A (de) 1996-03-15
GB2220949B (en) 1992-01-22
BE1003253A3 (fr) 1992-02-11
CH679371A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-02-14
RU1837871C (ru) 1993-08-30
JPH0651620B2 (ja) 1994-07-06
CY1761A (en) 1994-07-15
HU199678B (en) 1990-03-28
IT8921118A0 (it) 1989-07-07
GB8915632D0 (en) 1989-08-23

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BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed