IT1230742B - Composizione per aerosol comprendente nitroglicerina come ingrediente attivo. - Google Patents

Composizione per aerosol comprendente nitroglicerina come ingrediente attivo.

Info

Publication number
IT1230742B
IT1230742B IT8921118A IT2111889A IT1230742B IT 1230742 B IT1230742 B IT 1230742B IT 8921118 A IT8921118 A IT 8921118A IT 2111889 A IT2111889 A IT 2111889A IT 1230742 B IT1230742 B IT 1230742B
Authority
IT
Italy
Prior art keywords
composition
active ingredient
aerosol including
nitroglycerine
including nitroglycerine
Prior art date
Application number
IT8921118A
Other languages
English (en)
Italian (it)
Other versions
IT8921118A0 (it
Inventor
Margit Nagy
Jozsef Kenderfi
Frigyes Gorgenyi
Margit Csorgo
Lidia Fedina
Antal Mosonyi
Sandor Vajas
Attila Mandi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IT8921118A0 publication Critical patent/IT8921118A0/it
Application granted granted Critical
Publication of IT1230742B publication Critical patent/IT1230742B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/30—Materials not provided for elsewhere for aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
IT8921118A 1988-07-08 1989-07-07 Composizione per aerosol comprendente nitroglicerina come ingrediente attivo. IT1230742B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU883585A HU199678B (en) 1988-07-08 1988-07-08 Process for producing aerosols containing nitroglicerol

Publications (2)

Publication Number Publication Date
IT8921118A0 IT8921118A0 (it) 1989-07-07
IT1230742B true IT1230742B (it) 1991-10-29

Family

ID=10964655

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8921118A IT1230742B (it) 1988-07-08 1989-07-07 Composizione per aerosol comprendente nitroglicerina come ingrediente attivo.

Country Status (15)

Country Link
US (1) US5047230A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0651620B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT401613B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE1003253A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG89108A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH679371A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CY (1) CY1761A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3922650A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2633933B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2220949B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU199678B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1230742B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8901751A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU1837871C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UA (1) UA11237A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (47)

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DE4007705C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1990-03-10 1991-09-26 G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De
US5370862A (en) * 1990-06-13 1994-12-06 Schwarz Pharma Ag Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina
DE4018919C2 (de) * 1990-06-13 1994-08-25 Sanol Arznei Schwarz Gmbh Nitroglycerin-Spray
DE4026072A1 (de) * 1990-08-17 1992-02-20 Sanol Arznei Schwarz Gmbh Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray
DE4038203A1 (de) * 1990-11-30 1992-06-04 Kali Chemie Pharma Gmbh Pharmazeutische spray-zubereitungen mit coronaraktiven wirkstoffen
DK0719145T3 (da) * 1994-05-27 2001-01-02 Cellegy Pharma Inc Nitrogenoxiddonorpræparat til behandling af anale lidelser
ES2183001T3 (es) * 1995-06-27 2003-03-16 Boehringer Ingelheim Pharma Nuevo preparado medicamentoso estable para la produccion de aerosoles exentos de gas propulsor.
EP0910339B1 (en) * 1996-04-12 2005-02-02 Novadel Pharma Inc. Buccal polar spray
US20050163719A1 (en) * 1997-10-01 2005-07-28 Dugger Harry A.Iii Buccal, polar and non-polar spray containing diazepam
US20040141923A1 (en) * 1997-10-01 2004-07-22 Dugger Harry A. Buccal, polar and non-polar spray containing alprazolam
US20030095927A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders
US20040136913A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing sumatriptan
US20030077229A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
US20030077227A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20050281752A1 (en) * 1997-10-01 2005-12-22 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20050002867A1 (en) * 1997-10-01 2005-01-06 Novadel Pharma Inc. Buccal, polar and non-polar sprays containing propofol
US20040136914A1 (en) 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing ondansetron
US20030082107A1 (en) * 1997-10-01 2003-05-01 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer
US20030185761A1 (en) 1997-10-01 2003-10-02 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20030095926A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract
US20040136915A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing atropine
US20050287075A1 (en) * 1997-10-01 2005-12-29 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20050180923A1 (en) * 1997-10-01 2005-08-18 Dugger Harry A.Iii Buccal, polar and non-polar spray containing testosterone
EP1952802A3 (en) * 1997-10-01 2009-06-17 Novadel Pharma Inc. Buccal, polar and non-polar spray or capsule
US20030077228A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders
US20030190286A1 (en) * 1997-10-01 2003-10-09 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma
US7632517B2 (en) * 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US20090162300A1 (en) * 1997-10-01 2009-06-25 Dugger Iii Harry A Buccal, polar and non-polar spray containing alprazolam
DE19855097A1 (de) * 1998-11-28 2000-05-31 Wella Ag Pigmenthaltiges, verschäumbares Gel
WO2000047203A1 (en) * 1999-02-12 2000-08-17 Mqs, Inc. Formulation and system for intra-oral delivery of pharmaceutical agents
US10004684B2 (en) 2001-02-14 2018-06-26 Gw Pharma Limited Pharmaceutical formulations
GB0417675D0 (en) * 2004-08-09 2004-09-08 Futura Medical Dev Ltd Composition for promoting vascular smooth muscle relaxation
EP2767163A1 (en) * 2005-02-17 2014-08-20 Abbott Laboratories Transmucosal administration of drug compositions for treating and preventing disorders in animals
GB0602224D0 (en) * 2006-02-03 2006-03-15 Futura Medical Dev Ltd Composition for promoting vascular smooth muscle relaxation
JP2009534387A (ja) * 2006-04-19 2009-09-24 ノヴァデル ファーマ インコーポレイテッド 安定な含水アルコール性経口噴霧調剤物および方法
EP2124897A4 (en) * 2006-12-22 2012-05-09 Novadel Pharma Inc SPRAYING, ORAL, STABLE, SPRAY PREPARATIONS AND ASSOCIATED METHODS
WO2008141264A1 (en) * 2007-05-10 2008-11-20 Novadel Pharma Inc. Anti-insomnia compositions and methods
DE202008008079U1 (de) * 2008-06-16 2008-09-04 G. Pohl-Boskamp Gmbh & Co. Kg Pharmazeutische Zubereitung in Wasserdampf durchlässigen Behältern mit verbesserter Stabilität
ES2582309T3 (es) 2010-08-03 2016-09-12 G. Pohl-Boskamp Gmbh & Co. Kg Uso de trinitrato de glicerilo para el tratamiento de edema traumático
US20130331461A1 (en) 2011-02-25 2013-12-12 G. Pohl-Boskamp Gmbh & Co. Kg Stabilized Granules Containing Glyceryl Trinitrate
US9248099B2 (en) 2012-05-31 2016-02-02 Desmoid Aktiengesellschaft Use of stabilized granules containing glyceryl trinitrate for arteriogenesis
PL2668947T3 (pl) 2012-05-31 2017-06-30 G. Pohl-Boskamp Gmbh & Co. Kg Indukcja arteriogenezy donorem NO, takim jak nitrogliceryna
EP2878310B1 (en) * 2013-11-29 2017-01-11 G. Pohl-Boskamp GmbH & Co. KG Sprayable aqueous composition comprising glyceryl trinitrate
CN104984351B (zh) * 2015-06-15 2018-01-30 马应龙药业集团股份有限公司 一种硝酸甘油丙二醇溶液的制备方法
CN113125596B (zh) * 2021-04-07 2023-01-13 马应龙药业集团股份有限公司 一种高效液相色谱法测定硝酸甘油软膏中有关物质的方法
WO2025115019A1 (en) 2023-11-30 2025-06-05 Padagis Israel Pharmaceuticals Ltd. Stable nitroglycerin formulations

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE632504A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1962-05-24
US4001391A (en) * 1969-04-18 1977-01-04 Plough, Inc. Means for depositing aerosol sprays in buttery form
US4369173A (en) * 1974-11-27 1983-01-18 Wickhen Products, Inc. Antiperspirant compositions
IL61721A (en) * 1980-12-16 1984-03-30 Blank Izhak Nitroglycerin preparations
DE3109783C2 (de) * 1981-03-13 1987-04-02 Schwarz GmbH, 4019 Monheim Verfahren zur Herstellung einer ethanolfreien Nitroglycerinlösung mit einer Konzentration von etwa 1 mg Nitroglycerin/ml
US4440777A (en) * 1981-07-07 1984-04-03 Merck & Co., Inc. Use of eucalyptol for enhancing skin permeation of bio-affecting agents
DE3246081A1 (de) * 1982-12-13 1984-06-14 G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt Nitroglycerin-spray
EP0175671A1 (de) * 1984-08-23 1986-03-26 Kuhlemann & Co. Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung
US4885173A (en) * 1985-05-01 1989-12-05 University Of Utah Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
DE3613187A1 (de) * 1986-04-18 1987-10-22 Mack Chem Pharm Verwendung einer carbonsaeure in zur topischen anwendung bestimmten pharmazeutischen zubereitungen
JPH0645538B2 (ja) * 1987-09-30 1994-06-15 日本化薬株式会社 ニトログリセリンスプレー剤
DE4018919C2 (de) * 1990-06-13 1994-08-25 Sanol Arznei Schwarz Gmbh Nitroglycerin-Spray

Also Published As

Publication number Publication date
GB8915632D0 (en) 1989-08-23
US5047230A (en) 1991-09-10
JPH0651620B2 (ja) 1994-07-06
GB2220949A (en) 1990-01-24
BE1003253A3 (fr) 1992-02-11
DE3922650A1 (de) 1990-01-11
DE3922650C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-03-04
GB2220949B (en) 1992-01-22
JPH02142726A (ja) 1990-05-31
BG89108A (bg) 1993-12-24
ATA165489A (de) 1996-03-15
FR2633933B1 (fr) 1994-07-22
FR2633933A1 (fr) 1990-01-12
UA11237A (uk) 1996-12-25
NL8901751A (nl) 1990-02-01
IT8921118A0 (it) 1989-07-07
CY1761A (en) 1994-07-15
RU1837871C (ru) 1993-08-30
AT401613B (de) 1996-10-25
CH679371A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-02-14
HU199678B (en) 1990-03-28

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960730