ES2582309T3 - Uso de trinitrato de glicerilo para el tratamiento de edema traumático - Google Patents
Uso de trinitrato de glicerilo para el tratamiento de edema traumáticoInfo
- Publication number
- ES2582309T3 ES2582309T3 ES11748571.4T ES11748571T ES2582309T3 ES 2582309 T3 ES2582309 T3 ES 2582309T3 ES 11748571 T ES11748571 T ES 11748571T ES 2582309 T3 ES2582309 T3 ES 2582309T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- glyceryl trinitrate
- traumatic edema
- traumatic
- edema
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Trinitrato de glicerilo (GTN) para su uso en el tratamiento del edema traumático, en donde el edema traumático se caracteriza por la aparición temporal de las condiciones de hinchazón después de fracturas óseas, contusiones, esguinces, luxaciones, impactos, golpes o caídas, en donde el edema traumático no es linfidema postraumático secundario, y en donde se aplica por vía tópica el trinitrato de glicerilo (GTN).
Description
Claims (1)
-
imagen1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102010033182 | 2010-08-03 | ||
DE102010033182 | 2010-08-03 | ||
PCT/EP2011/003890 WO2012016691A1 (en) | 2010-08-03 | 2011-08-03 | Use of glyceryl trinitrate for treating traumatic edema |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2582309T3 true ES2582309T3 (es) | 2016-09-12 |
Family
ID=44509174
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES11748571.4T Active ES2582309T3 (es) | 2010-08-03 | 2011-08-03 | Uso de trinitrato de glicerilo para el tratamiento de edema traumático |
Country Status (7)
Country | Link |
---|---|
US (3) | US20130121930A1 (es) |
EP (3) | EP2600837A1 (es) |
AU (1) | AU2011287948B2 (es) |
CA (1) | CA2806636C (es) |
ES (1) | ES2582309T3 (es) |
PL (1) | PL2467128T3 (es) |
WO (2) | WO2012016690A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2600837A1 (en) * | 2010-08-03 | 2013-06-12 | G. Pohl-Boskamp GmbH & Co. KG | Use of glyceryl trinitrate for treating hematomas |
PL2668947T3 (pl) | 2012-05-31 | 2017-06-30 | G. Pohl-Boskamp Gmbh & Co. Kg | Indukcja arteriogenezy donorem NO, takim jak nitrogliceryna |
AT513312A1 (de) * | 2012-08-17 | 2014-03-15 | Gebro Holding Gmbh | Antiseptische Zusammensetzung |
WO2014193804A1 (en) * | 2013-05-28 | 2014-12-04 | Biogen Idec Ma Inc. | Method of assessing risk of pml |
JP6951074B2 (ja) * | 2014-03-28 | 2021-10-20 | エス.シー. ジョンソン アンド サン、インコーポレイテッド | ポンプの濃縮空気清浄剤 |
GB2592376A (en) * | 2020-02-25 | 2021-09-01 | Aer Beatha Ltd | Canister |
Family Cites Families (50)
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BE632504A (es) | 1962-05-24 | |||
GB1205019A (en) | 1966-12-07 | 1970-09-09 | Sterwin Ag | Improvements in or relating to oral dosage forms |
JPS599539B2 (ja) | 1979-11-13 | 1984-03-03 | 日本化薬株式会社 | ニトログリセリン水溶液及びその製造法 |
CA1163195A (en) | 1980-06-26 | 1984-03-06 | Alec D. Keith | Polymeric diffusion matrix containing a vasodilator |
US4542013A (en) | 1981-07-08 | 1985-09-17 | Key Pharmaceuticals, Inc. | Trinitroglycerol sustained release vehicles and preparation therefrom |
DE3246081A1 (de) | 1982-12-13 | 1984-06-14 | G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt | Nitroglycerin-spray |
EP0583821B1 (en) | 1987-01-23 | 2000-03-29 | The General Hospital Corporation | Hydralazine as topical treatment for glaucoma |
JPH0645538B2 (ja) * | 1987-09-30 | 1994-06-15 | 日本化薬株式会社 | ニトログリセリンスプレー剤 |
HU199678B (en) | 1988-07-08 | 1990-03-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing aerosols containing nitroglicerol |
DE4007705C1 (es) | 1990-03-10 | 1991-09-26 | G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De | |
DE4018919C2 (de) * | 1990-06-13 | 1994-08-25 | Sanol Arznei Schwarz Gmbh | Nitroglycerin-Spray |
US5370862A (en) | 1990-06-13 | 1994-12-06 | Schwarz Pharma Ag | Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina |
DE4026072A1 (de) | 1990-08-17 | 1992-02-20 | Sanol Arznei Schwarz Gmbh | Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray |
DE4038203A1 (de) * | 1990-11-30 | 1992-06-04 | Kali Chemie Pharma Gmbh | Pharmazeutische spray-zubereitungen mit coronaraktiven wirkstoffen |
US5698589A (en) | 1993-06-01 | 1997-12-16 | International Medical Innovations, Inc. | Water-based topical cream containing nitroglycerin and method of preparation and use thereof |
US5869082A (en) | 1996-04-12 | 1999-02-09 | Flemington Pharmaceutical Corp. | Buccal, non-polar spray for nitroglycerin |
US20010044584A1 (en) | 1997-08-28 | 2001-11-22 | Kensey Kenneth R. | In vivo delivery methods and compositions |
US20030095925A1 (en) | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders |
DE69802832T2 (de) | 1997-10-03 | 2002-06-20 | Warner Lambert Co | Gepresste nitroglycerintablette und verfahren zu ihrer herstellung |
US6796966B2 (en) | 1997-10-15 | 2004-09-28 | Jeffrey E. Thomas | Apparatus, and kits for preventing of alleviating vasoconstriction or vasospasm in a mammal |
AU2479099A (en) | 1998-01-28 | 1999-08-16 | Seatrace Pharmaceuticals, Inc. | Topical vasodilatory gel composition and methods of use and production |
US5989529A (en) * | 1998-11-20 | 1999-11-23 | Schering-Plough Healthcare Products, Inc. | Substantive topical composition |
IT1303793B1 (it) | 1998-11-27 | 2001-02-23 | Promefarm S R L | "composizione farmaceutica comprendente un composto organico donatoredi ossido nitrico (no)" |
US6962691B1 (en) | 1999-05-20 | 2005-11-08 | U & I Pharmaceuticals Ltd. | Topical spray compositions |
RU2174838C2 (ru) * | 1999-11-04 | 2001-10-20 | Ивановская государственная медицинская академия | Способ лечения тяжелого бронхообструктивного синдрома у детей раннего возраста |
AU2727701A (en) | 1999-12-15 | 2001-06-25 | Cellegy Pharmaceuticals, Inc. | Nitroglycerin ointment for treatment of pain associated with anal disease |
US6443307B1 (en) | 2000-01-25 | 2002-09-03 | Michael D. Burridge | Medication dispenser with an internal ejector |
US20010048987A1 (en) | 2000-03-14 | 2001-12-06 | David Kanios | Packaging materials for transdermal drug delivery systems |
US6538033B2 (en) | 2000-08-29 | 2003-03-25 | Huntington Medical Research Institutes | Nitric oxide donor compounds |
ATE480226T1 (de) | 2001-06-22 | 2010-09-15 | Bend Res Inc | Pharmazeutische zusammensetzung enthaltend schwer lösliche und säureempfindliche arzneistoffe und neutralisierte anionische polymere |
PL202643B1 (pl) | 2002-02-08 | 2009-07-31 | Procter & Gamble | Saszetka trzyszwowa do ciekłego lub proszkowego wyrobu medycznego |
US20050095278A1 (en) | 2003-01-14 | 2005-05-05 | Viorel Nicolaescu | Use of nitroglycerin to relieve nocturnal muscle cramps |
US20040228883A1 (en) | 2003-02-21 | 2004-11-18 | Mitchell Karl | Prepackaged aqueous pharmaceutical formulation for the treatment of cardiac conditions containing at least two different active agents and method of formulation |
WO2005004989A2 (en) | 2003-07-01 | 2005-01-20 | Todd Maibach | Film comprising therapeutic agents |
US20070053966A1 (en) * | 2003-10-17 | 2007-03-08 | Robert Ang | Medicated orthopedic support structures for treatment of damaged musculoskeletal tissue |
US7781226B2 (en) | 2004-02-27 | 2010-08-24 | The Board Of Regents Of The University Of Texas System | Particle on membrane assay system |
CA2557814A1 (en) | 2004-03-01 | 2005-09-15 | Lumen Therapeutics, Llc | Compositions and methods for treating diseases |
US20080260861A1 (en) * | 2004-04-07 | 2008-10-23 | The General Hospital Corporation | Modulating Lymphatic Function |
CA2636638C (en) | 2006-01-09 | 2014-02-18 | Pantarhei Bioscience B.V. | A method of treating an acute vascular disorder |
CA2649895C (en) | 2006-04-19 | 2013-03-26 | Novadel Pharma Inc. | Stable hydroalcoholic oral spray formulations and methods |
US20080193385A1 (en) * | 2007-02-08 | 2008-08-14 | Todd Maibach | Compositions and methods for treating neuropathy |
US10406118B2 (en) | 2007-02-26 | 2019-09-10 | Jon Lundberg | Use of nitrites and nitrates and compositions containing these |
CN101229148A (zh) | 2007-12-28 | 2008-07-30 | 天津医科大学 | 硝酸甘油口腔(舌下)崩解片的制剂及其制备方法 |
DE102008005484A1 (de) | 2008-01-22 | 2009-07-23 | Schaper, Wolfgang, Dr. | Induktion und Förderung der Arteriogenese |
PL2098249T3 (pl) | 2008-03-05 | 2013-03-29 | Rivopharm Sa | Nośniki o zwiększonej trwałości dla nikorandylu |
US20100184870A1 (en) * | 2008-03-14 | 2010-07-22 | Rolf Groteluschen | Long-term stable pharmaceutical preparation containing the active ingredient glycerol trinitrate |
DE202008007318U1 (de) | 2008-03-14 | 2008-07-31 | G. Pohl-Boskamp Gmbh & Co. Kg | Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat |
WO2010011650A1 (en) * | 2008-07-21 | 2010-01-28 | Imi International Medical Innovations (D/B/A Procris Pharmaceuticals) | Stable water-based topical pharmaceutical creams and methods of making and using same |
CA3130908A1 (en) | 2009-06-30 | 2010-12-30 | Mallinckrodt Hospital Products IP Limited | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
EP2600837A1 (en) * | 2010-08-03 | 2013-06-12 | G. Pohl-Boskamp GmbH & Co. KG | Use of glyceryl trinitrate for treating hematomas |
-
2011
- 2011-08-03 EP EP11745927.1A patent/EP2600837A1/en not_active Withdrawn
- 2011-08-03 US US13/813,685 patent/US20130121930A1/en not_active Abandoned
- 2011-08-03 AU AU2011287948A patent/AU2011287948B2/en not_active Ceased
- 2011-08-03 PL PL11748571.4T patent/PL2467128T3/pl unknown
- 2011-08-03 ES ES11748571.4T patent/ES2582309T3/es active Active
- 2011-08-03 WO PCT/EP2011/003888 patent/WO2012016690A1/en active Application Filing
- 2011-08-03 EP EP11748571.4A patent/EP2467128B1/en not_active Not-in-force
- 2011-08-03 EP EP15002812.4A patent/EP2990032A1/en not_active Withdrawn
- 2011-08-03 CA CA2806636A patent/CA2806636C/en not_active Expired - Fee Related
- 2011-08-03 US US13/813,676 patent/US9180109B2/en not_active Expired - Fee Related
- 2011-08-03 WO PCT/EP2011/003890 patent/WO2012016691A1/en active Application Filing
-
2015
- 2015-09-30 US US14/870,870 patent/US9693983B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US9180109B2 (en) | 2015-11-10 |
EP2600837A1 (en) | 2013-06-12 |
US20130129638A1 (en) | 2013-05-23 |
WO2012016690A1 (en) | 2012-02-09 |
EP2467128A1 (en) | 2012-06-27 |
PL2467128T3 (pl) | 2016-10-31 |
AU2011287948B2 (en) | 2014-11-06 |
CA2806636C (en) | 2018-01-23 |
CA2806636A1 (en) | 2012-02-09 |
WO2012016691A1 (en) | 2012-02-09 |
US20160213637A1 (en) | 2016-07-28 |
US9693983B2 (en) | 2017-07-04 |
AU2011287948A1 (en) | 2013-02-07 |
US20130121930A1 (en) | 2013-05-16 |
EP2990032A1 (en) | 2016-03-02 |
EP2467128B1 (en) | 2016-04-13 |
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