ES2496092T3 - El uso de amisulprida para tratar náuseas y vómitos posoperatorios - Google Patents

El uso de amisulprida para tratar náuseas y vómitos posoperatorios Download PDF

Info

Publication number
ES2496092T3
ES2496092T3 ES11709793.1T ES11709793T ES2496092T3 ES 2496092 T3 ES2496092 T3 ES 2496092T3 ES 11709793 T ES11709793 T ES 11709793T ES 2496092 T3 ES2496092 T3 ES 2496092T3
Authority
ES
Spain
Prior art keywords
amisulpride
vomiting
postoperative nausea
treat postoperative
treat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11709793.1T
Other languages
English (en)
Inventor
Julian Clive Gilbert
Robert William Gristwood
Nicola Cooper
Gabriel Fox
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acacia Pharma Ltd
Original Assignee
Acacia Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42136792&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2496092(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Acacia Pharma Ltd filed Critical Acacia Pharma Ltd
Application granted granted Critical
Publication of ES2496092T3 publication Critical patent/ES2496092T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Amisulprida para su uso en la terapia de náuseas y vómitos posoperatorios.

Description

imagen1
imagen2
imagen3
imagen4
imagen5
imagen6

Claims (1)

  1. imagen1
ES11709793.1T 2010-03-11 2011-03-10 El uso de amisulprida para tratar náuseas y vómitos posoperatorios Active ES2496092T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1004020.2A GB201004020D0 (en) 2010-03-11 2010-03-11 New therapeutic use
GB201004020 2010-03-11
PCT/GB2011/050472 WO2011110854A2 (en) 2010-03-11 2011-03-10 The use of amisulpride as an anti-emetic

Publications (1)

Publication Number Publication Date
ES2496092T3 true ES2496092T3 (es) 2014-09-18

Family

ID=42136792

Family Applications (3)

Application Number Title Priority Date Filing Date
ES14173186.9T Active ES2665418T3 (es) 2010-03-11 2011-03-10 Uso de amisulprida para tratar náuseas y vómitos inducidos por opiáceos
ES11709793.1T Active ES2496092T3 (es) 2010-03-11 2011-03-10 El uso de amisulprida para tratar náuseas y vómitos posoperatorios
ES12188047.0T Active ES2496099T3 (es) 2010-03-11 2011-03-10 El uso de amisulprida para el tratamiento de náuseas y vómitos inducidos por la quimioterapia

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES14173186.9T Active ES2665418T3 (es) 2010-03-11 2011-03-10 Uso de amisulprida para tratar náuseas y vómitos inducidos por opiáceos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES12188047.0T Active ES2496099T3 (es) 2010-03-11 2011-03-10 El uso de amisulprida para el tratamiento de náuseas y vómitos inducidos por la quimioterapia

Country Status (27)

Country Link
US (11) US9084765B2 (es)
EP (3) EP2544657B1 (es)
JP (2) JP5886213B2 (es)
KR (1) KR101738201B1 (es)
CN (1) CN102892407B (es)
AU (1) AU2011225898B2 (es)
BR (1) BR112012022746B1 (es)
CA (1) CA2792392C (es)
CY (3) CY1115487T1 (es)
DK (3) DK2567690T3 (es)
EA (1) EA030335B1 (es)
ES (3) ES2665418T3 (es)
GB (1) GB201004020D0 (es)
HK (1) HK1179152A1 (es)
HR (3) HRP20140744T1 (es)
HU (1) HUE037088T2 (es)
IL (1) IL221746A (es)
LT (1) LT2796171T (es)
MX (3) MX370629B (es)
NO (1) NO2796171T3 (es)
NZ (1) NZ602279A (es)
PL (3) PL2796171T3 (es)
PT (3) PT2567690E (es)
RS (3) RS53466B (es)
SI (3) SI2796171T1 (es)
SM (2) SMT201400126B (es)
WO (1) WO2011110854A2 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201004020D0 (en) 2010-03-11 2010-04-21 Acacia Pharma Ltd New therapeutic use
CN104435861A (zh) * 2014-12-22 2015-03-25 济南伟传信息技术有限公司 一种治疗妊娠剧吐的茶
GB201506116D0 (en) * 2015-04-10 2015-05-27 Acacia Pharma Ltd Kit and combination therapy for nausea and vomiting
WO2017040848A1 (en) 2015-09-02 2017-03-09 California Institute Of Technology Method and apparatus for the spectroscopic detection of low concentrations of hydrogen sulfide gas
GB201618425D0 (en) 2016-11-01 2016-12-14 Acacia Pharma Ltd method
GB201702250D0 (en) * 2017-02-10 2017-03-29 Acacia Pharma Ltd Method
WO2019113084A1 (en) 2017-12-05 2019-06-13 Sunovion Pharmaceuticals Inc. Crystal forms and production methods thereof
BR112020011189A2 (pt) 2017-12-05 2020-11-17 Sunovion Pharmaceuticals Inc. misturas não racêmicas e usos das mesmas
WO2020247603A1 (en) * 2019-06-04 2020-12-10 Sunovion Pharmaceuticals Inc. Modified release formulations and uses thereof
US11160758B2 (en) 2019-06-04 2021-11-02 Sunovion Pharmaceuticals Inc. Modified release formulations and uses thereof
MX2023000283A (es) 2020-07-06 2023-02-09 Acacia Pharma Ltd Terapia de nausea y vomito post-operatorio.
WO2023179542A1 (en) 2022-03-21 2023-09-28 Gasherbrum Bio , Inc. 5,8-dihydro-1,7-naphthyridine derivatives as glp-1 agonists for the treatment of diabetes
WO2023198140A1 (en) 2022-04-14 2023-10-19 Gasherbrum Bio, Inc. Heterocyclic glp-1 agonists
WO2024125602A1 (en) 2022-12-15 2024-06-20 Gasherbrum Bio, Inc. Salts and solid forms of a compound having glp-1 agonist activity
WO2024138048A1 (en) 2022-12-22 2024-06-27 Gasherbrum Bio, Inc. Heterocyclic glp-1 agonists
WO2024131869A1 (en) 2022-12-22 2024-06-27 Gasherbrum Bio, Inc. Heterocyclic glp-1 agonists
WO2024169952A1 (en) 2023-02-16 2024-08-22 Gasherbrum Bio, Inc. Heterocyclic glp-1 agonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2415099A1 (fr) * 1978-01-20 1979-08-17 Ile De France Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes
US6169094B1 (en) * 1998-07-14 2001-01-02 Sanofi-Synthelabo Compositions of (S) (-)-amisulpride
DE10163421A1 (de) * 2001-12-21 2003-07-31 Gruenenthal Gmbh Verwendung von (+)-(1S,2S)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)phenol als Antiemetikum
DE102005013726A1 (de) * 2005-03-22 2006-09-28 Grünenthal GmbH Transdermale therapeutische Systeme mit verbesserter Verträglichkeit
GB0506800D0 (en) * 2005-04-04 2005-05-11 Merck Sharp & Dohme New uses
WO2007067714A2 (en) * 2005-12-08 2007-06-14 The Mclean Hospital Corporation Treatment of sequelae of psychiatric disorders
BRPI0707324A2 (pt) 2006-01-27 2011-05-03 Eurand Inc sistemas de fornecimento de fármaco compreendendo agente de bloqueio de serotonina 5-ht3 seletivo fracamente básico e ácidos orgánicos
WO2007096489A1 (fr) * 2006-02-17 2007-08-30 Trimaran Limited Nouvelles compositions pharmaceutiques destinees a optimiser des traitements de substitution et elargir la pharmacopee au traitement global des addictions
US7825156B2 (en) * 2007-02-02 2010-11-02 Copharms Method of treating bipolar depression with a benzamide derivative
ES2620672T3 (es) * 2008-01-09 2017-06-29 Charleston Laboratories, Inc. Comprimidos de doble capa que comprenden oxicodona y prometazina
US8138169B2 (en) * 2008-04-11 2012-03-20 Comgenrx, Inc. Combination therapy for bipolar disorder
GB201004020D0 (en) 2010-03-11 2010-04-21 Acacia Pharma Ltd New therapeutic use

Also Published As

Publication number Publication date
EP2796171B1 (en) 2018-01-31
US20200093792A1 (en) 2020-03-26
RS53466B (en) 2014-12-31
SMT201400127B (it) 2015-05-05
EP2544657B1 (en) 2014-07-16
KR101738201B1 (ko) 2017-05-19
PT2796171T (pt) 2018-04-24
PL2796171T3 (pl) 2018-07-31
WO2011110854A3 (en) 2011-11-10
AU2011225898B2 (en) 2014-07-03
MX2019015396A (es) 2020-02-07
US20180353473A1 (en) 2018-12-13
HRP20140745T1 (hr) 2014-09-26
US20170087128A1 (en) 2017-03-30
US20220296570A1 (en) 2022-09-22
EP2567690B1 (en) 2014-07-16
US20180042896A1 (en) 2018-02-15
BR112012022746B1 (pt) 2021-09-28
JP2013522181A (ja) 2013-06-13
DK2567690T3 (da) 2014-08-11
HK1179152A1 (zh) 2013-09-27
CN102892407A (zh) 2013-01-23
PT2544657E (pt) 2014-09-03
EP2796171A1 (en) 2014-10-29
RS53467B (en) 2014-12-31
EP2567690A1 (en) 2013-03-13
NO2796171T3 (es) 2018-06-30
RS57032B1 (sr) 2018-05-31
US20140147517A1 (en) 2014-05-29
CN102892407B (zh) 2016-03-23
MX2012010411A (es) 2012-11-30
US20230144973A1 (en) 2023-05-11
EA201290833A1 (ru) 2013-09-30
IL221746A (en) 2017-03-30
JP5886213B2 (ja) 2016-03-16
PL2567690T3 (pl) 2014-11-28
DK2544657T3 (da) 2014-08-11
JP2016028090A (ja) 2016-02-25
SI2796171T1 (en) 2018-05-31
JP6279526B2 (ja) 2018-02-14
CA2792392A1 (en) 2011-09-15
AU2011225898A1 (en) 2012-10-04
EP2544657A2 (en) 2013-01-16
US20150335616A1 (en) 2015-11-26
ES2665418T3 (es) 2018-04-25
SI2567690T1 (sl) 2014-12-31
WO2011110854A2 (en) 2011-09-15
ES2496099T3 (es) 2014-09-18
US10525033B2 (en) 2020-01-07
CY1115485T1 (el) 2017-01-04
EA030335B1 (ru) 2018-07-31
US9545426B2 (en) 2017-01-17
LT2796171T (lt) 2018-05-10
HUE037088T2 (hu) 2018-08-28
BR112012022746A2 (pt) 2016-07-05
US8686019B2 (en) 2014-04-01
HRP20180436T1 (hr) 2018-05-04
SMT201400126B (it) 2015-05-05
US9084765B2 (en) 2015-07-21
US9119836B2 (en) 2015-09-01
PT2567690E (pt) 2014-09-03
US20210228543A1 (en) 2021-07-29
US10085970B2 (en) 2018-10-02
CY1115487T1 (el) 2017-01-04
SI2544657T1 (sl) 2014-12-31
CA2792392C (en) 2018-06-19
US20130022688A1 (en) 2013-01-24
US20130022689A1 (en) 2013-01-24
MX370629B (es) 2019-12-18
GB201004020D0 (en) 2010-04-21
DK2796171T3 (en) 2018-05-07
HRP20140744T1 (hr) 2014-09-26
NZ602279A (en) 2014-08-29
CY1120170T1 (el) 2018-12-12
KR20130045241A (ko) 2013-05-03
US9889118B2 (en) 2018-02-13
PL2544657T3 (pl) 2014-10-31

Similar Documents

Publication Publication Date Title
ES2496092T3 (es) El uso de amisulprida para tratar náuseas y vómitos posoperatorios
ES2502472T3 (es) Composición adhesiva para su uso en un inmunosensor
ECSP24031979A (es) Compuestos terapéuticamente activos y sus métodos de uso
ES2661582T3 (es) Efecto antiinflamatorio de la celulosa microfibrilada
ES2665917T3 (es) Endoxifeno para su uso en el tratamiento del cáncer
CL2012003281A1 (es) Uso de compuestos específicos estimuladores y/o activadores de sgc; formulacion farmaceutica que comprende dichos compuestos; kit que comprende los compuestos, y uso para la prevencion y/o tratamiento de la esclerosis sistematica.
GT201300320A (es) Terapia de combinación que comprende un inhibidor de cdk4/6 y un inhibidor de pi3k para el uso en el tratamiento de cáncer.
CL2008001633A1 (es) Compuestos derivados de pirrolidin-3-carboxamida; composición farmacéutica; y uso comominhibidores de erk para el tratamiento del cancer.
CL2008002042A1 (es) Compuestos derivados de heterociclos nitrogenados enlazados; y su uso en el tratamiento de la diabetes y desordenes metabolicos.
ES2486615A2 (es) Formulación, resina o extruido para conformar una estructura celular aislante, polimérica y no aromática, artículo y material que se obtiene, recipiente conformado y proceso de obtención.
ES2488407T3 (es) Preparación farmacéutica que contiene lipasa de origen bacteriano
CL2013000018A1 (es) Compuestos derivados de indolizina , su procedimiento de preparacion; composicion farmaceutica; y uso en el tratamiento del cancer, entre otros.
ES2620754T3 (es) Uso de 5-androstano (alquil)-3,5,6-triol en la preparación de fármacos neuroprotectores
IT1392903B1 (it) Composizione comprendente un'associazione di principi attivi per uso nel trattamento topico della calvizie
CL2012002173A1 (es) Combinacion de al menos un estimulador o activador de la sgc con un inhibidor de la pde5; formulacion farmaceutica; y uso para el tratamiento de la fibrosis quistica.
GT201000047A (es) Mejoras en compuestos organicos o relacionadas con los mismos
BR112013001423A2 (pt) método, método in vitro, uso e kit útil para realizar o método
CL2012002887A1 (es) Combinación farmacéutica que comprende compuestos derivados de 2,3-dihidroimidazo[1,2-c]quinazolina sustituida, compuestos derivados de n-(2-arilamino)arilsulfonamida y opcionalmente otros agentes farmacéuticos adicionales; kit faramacéutico; método de tratamiento; y su uso para el tratamiento o la profilaxis del cáncer.
ES2508165T3 (es) Lactoferrina y sustancia blanca
ES2482168T3 (es) Uso de opioides del grupo de la metadona para el tratamiento de pacientes con cáncer resistente
ES2629309T3 (es) Formulaciones de tratamiento de la mucositis inducida por terapia antitumoral o inmunosupresora
ES2642085T3 (es) Procedimientos anaeróbicos de tratamiento de lodos
CL2012001757A1 (es) Compuestos derivados de 8-hidroxiquinolina-7-carboxamida; composicion farmaceutica; y su uso en el tratamiento de infecciones micoticas.
TW200716653A (en) Azolopyridin-2-one derivatives as inhibitors of lipases and phospholipases
DOP2010000361A (es) Dronedarona para la prevencion de la cardioversion