HRP20140744T1 - Uporaba amisulprida za lijeäśenje post-operativne muäśnine i povraä†anja - Google Patents

Uporaba amisulprida za lijeäśenje post-operativne muäśnine i povraä†anja Download PDF

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Publication number
HRP20140744T1
HRP20140744T1 HRP20140744AT HRP20140744T HRP20140744T1 HR P20140744 T1 HRP20140744 T1 HR P20140744T1 HR P20140744A T HRP20140744A T HR P20140744AT HR P20140744 T HRP20140744 T HR P20140744T HR P20140744 T1 HRP20140744 T1 HR P20140744T1
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HR
Croatia
Prior art keywords
amisulpride
use according
vomiting
patient
operative nausea
Prior art date
Application number
HRP20140744AT
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English (en)
Inventor
Julian Clive Gilbert
Robert William Gristwood
Nicola Cooper
Gabriel Fox
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Acacia Pharma Limited
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42136792&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20140744(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Acacia Pharma Limited filed Critical Acacia Pharma Limited
Publication of HRP20140744T1 publication Critical patent/HRP20140744T1/hr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Claims (12)

1. Amisulprid za uporabu u liječenju post-operativne mučnine i povraćanja.
2. Amisulprid za uporabu prema zahtjevu 1, gdje liječeni bolesnik također dobiva i opijat.
3. Amisulprid za uporabu prema zahtjevu 2 gdje liječeni bolesnik također dobiva i morfij.
4. Amisulprid za uporabu prema bilo kojem od prethodnih zahtjeva, za primjenu intravenskom, intramuskularnom ili subkutanom injekcijom.
5. Amisulprid za uporabu prema bilo kojem od zahtjeva 1 do 3, za primjenu oralnim, transdermalnim, sublingvalnim putem ili inhalacijom.
6. Amisulprid za uporabu prema bilo kojem od prethodnih zahtjeva, gdje je liječeni bolesnik čovjek.
7. Amisulprid za uporabu prema bilo kojem od prethodnih zahtjeva, u obliku pojedinačne doze koja sadrži manje od 50 mg amisulprida.
8. Amisulprid za uporabu prema zahtjevu 7, gdje pojedinačna doza sadrži 1 do 35 mg amisulprida.
9. Amisulprid za uporabu prema zahtjevu 8, gdje se pojedinačna doza od 1 do 35 mg daje jednom ili dva puta na dan ljudskom bolesniku. .
10. Amisulprid za uporabu prema bilo kojem od prethodnih zahtjeva, za uporabu u kombinaciji s drugim antiemetikom.
11. Amisulprid za uporabu prema zahtjevu 10, gdje je taj drugi antiemetik 5HT3 antagonist.
12. Amisulprid za uporabu prema zahtjevu 11, gdje je 5HT3 antagonist ondansetron.
HRP20140744AT 2010-03-11 2014-08-01 Uporaba amisulprida za lijeäśenje post-operativne muäśnine i povraä†anja HRP20140744T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1004020.2A GB201004020D0 (en) 2010-03-11 2010-03-11 New therapeutic use
PCT/GB2011/050472 WO2011110854A2 (en) 2010-03-11 2011-03-10 The use of amisulpride as an anti-emetic

Publications (1)

Publication Number Publication Date
HRP20140744T1 true HRP20140744T1 (hr) 2014-09-26

Family

ID=42136792

Family Applications (3)

Application Number Title Priority Date Filing Date
HRP20140745AT HRP20140745T1 (hr) 2010-03-11 2014-08-01 Uporaba amisulprida za lijeäśenje kemoterapijom izazvane muäśnine i povraä†anja
HRP20140744AT HRP20140744T1 (hr) 2010-03-11 2014-08-01 Uporaba amisulprida za lijeäśenje post-operativne muäśnine i povraä†anja
HRP20180436TT HRP20180436T1 (hr) 2010-03-11 2018-03-14 Upotreba amisulprida u liječenju mučnine i povraćanja uzrokovanih opijatima

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HRP20140745AT HRP20140745T1 (hr) 2010-03-11 2014-08-01 Uporaba amisulprida za lijeäśenje kemoterapijom izazvane muäśnine i povraä†anja

Family Applications After (1)

Application Number Title Priority Date Filing Date
HRP20180436TT HRP20180436T1 (hr) 2010-03-11 2018-03-14 Upotreba amisulprida u liječenju mučnine i povraćanja uzrokovanih opijatima

Country Status (27)

Country Link
US (11) US9084765B2 (hr)
EP (3) EP2567690B1 (hr)
JP (2) JP5886213B2 (hr)
KR (1) KR101738201B1 (hr)
CN (1) CN102892407B (hr)
AU (1) AU2011225898B2 (hr)
BR (1) BR112012022746B1 (hr)
CA (1) CA2792392C (hr)
CY (3) CY1115485T1 (hr)
DK (3) DK2796171T3 (hr)
EA (1) EA030335B1 (hr)
ES (3) ES2496099T3 (hr)
GB (1) GB201004020D0 (hr)
HK (1) HK1179152A1 (hr)
HR (3) HRP20140745T1 (hr)
HU (1) HUE037088T2 (hr)
IL (1) IL221746A (hr)
LT (1) LT2796171T (hr)
MX (3) MX2012010411A (hr)
NO (1) NO2796171T3 (hr)
NZ (1) NZ602279A (hr)
PL (3) PL2796171T3 (hr)
PT (3) PT2796171T (hr)
RS (3) RS53466B (hr)
SI (3) SI2796171T1 (hr)
SM (2) SMT201400127B (hr)
WO (1) WO2011110854A2 (hr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201004020D0 (en) * 2010-03-11 2010-04-21 Acacia Pharma Ltd New therapeutic use
CN104435861A (zh) * 2014-12-22 2015-03-25 济南伟传信息技术有限公司 一种治疗妊娠剧吐的茶
GB201506116D0 (en) 2015-04-10 2015-05-27 Acacia Pharma Ltd Kit and combination therapy for nausea and vomiting
EP3344962A4 (en) 2015-09-02 2019-03-13 California Institute of Technology METHOD AND APPARATUS FOR SPECTROSCOPIC DETECTION OF LOW HYDROGEN SULFIDE CONCENTRATIONS GASEOUS
GB201618425D0 (en) * 2016-11-01 2016-12-14 Acacia Pharma Ltd method
GB201702250D0 (en) 2017-02-10 2017-03-29 Acacia Pharma Ltd Method
AU2018378348A1 (en) 2017-12-05 2020-06-18 Sunovion Pharmaceuticals Inc. Crystal forms and production methods thereof
WO2019113079A1 (en) 2017-12-05 2019-06-13 Sunovion Pharmaceuticals Inc. Nonracemic mixtures and uses thereof
US20220323409A1 (en) * 2019-06-04 2022-10-13 Sunovion Pharmaceuticals Inc. Modified release formulations and uses thereof
CA3142355A1 (en) 2019-06-04 2020-12-10 Sunovion Pharmaceuticals Inc. Modified release formulations and uses thereof
EP4175631A1 (en) 2020-07-06 2023-05-10 Acacia Pharma Ltd Therapy of post-operative nausea and vomiting
WO2023179542A1 (en) 2022-03-21 2023-09-28 Gasherbrum Bio , Inc. 5,8-dihydro-1,7-naphthyridine derivatives as glp-1 agonists for the treatment of diabetes
WO2023198140A1 (en) 2022-04-14 2023-10-19 Gasherbrum Bio, Inc. Heterocyclic glp-1 agonists

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US6169094B1 (en) * 1998-07-14 2001-01-02 Sanofi-Synthelabo Compositions of (S) (-)-amisulpride
DE10163421A1 (de) * 2001-12-21 2003-07-31 Gruenenthal Gmbh Verwendung von (+)-(1S,2S)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)phenol als Antiemetikum
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Also Published As

Publication number Publication date
US20130022689A1 (en) 2013-01-24
US10525033B2 (en) 2020-01-07
AU2011225898B2 (en) 2014-07-03
HRP20140745T1 (hr) 2014-09-26
DK2796171T3 (en) 2018-05-07
US9545426B2 (en) 2017-01-17
US20180353473A1 (en) 2018-12-13
BR112012022746A2 (pt) 2016-07-05
MX2019015396A (es) 2020-02-07
SMT201400127B (it) 2015-05-05
RS57032B1 (sr) 2018-05-31
EP2544657B1 (en) 2014-07-16
SI2567690T1 (sl) 2014-12-31
US20170087128A1 (en) 2017-03-30
EA201290833A1 (ru) 2013-09-30
US20230144973A1 (en) 2023-05-11
CY1120170T1 (el) 2018-12-12
ES2496092T3 (es) 2014-09-18
IL221746A (en) 2017-03-30
US20200093792A1 (en) 2020-03-26
US20150335616A1 (en) 2015-11-26
CA2792392C (en) 2018-06-19
SI2796171T1 (en) 2018-05-31
EP2567690A1 (en) 2013-03-13
NO2796171T3 (hr) 2018-06-30
NZ602279A (en) 2014-08-29
WO2011110854A2 (en) 2011-09-15
AU2011225898A1 (en) 2012-10-04
BR112012022746B1 (pt) 2021-09-28
PT2796171T (pt) 2018-04-24
KR101738201B1 (ko) 2017-05-19
US20220296570A1 (en) 2022-09-22
JP2013522181A (ja) 2013-06-13
MX2012010411A (es) 2012-11-30
US9889118B2 (en) 2018-02-13
JP6279526B2 (ja) 2018-02-14
ES2496099T3 (es) 2014-09-18
US20140147517A1 (en) 2014-05-29
EA030335B1 (ru) 2018-07-31
EP2544657A2 (en) 2013-01-16
KR20130045241A (ko) 2013-05-03
CN102892407A (zh) 2013-01-23
SI2544657T1 (sl) 2014-12-31
EP2567690B1 (en) 2014-07-16
US9119836B2 (en) 2015-09-01
CN102892407B (zh) 2016-03-23
CY1115485T1 (el) 2017-01-04
PT2567690E (pt) 2014-09-03
LT2796171T (lt) 2018-05-10
PL2796171T3 (pl) 2018-07-31
WO2011110854A3 (en) 2011-11-10
GB201004020D0 (en) 2010-04-21
EP2796171A1 (en) 2014-10-29
PL2544657T3 (pl) 2014-10-31
US20180042896A1 (en) 2018-02-15
JP5886213B2 (ja) 2016-03-16
RS53466B (en) 2014-12-31
US20130022688A1 (en) 2013-01-24
EP2796171B1 (en) 2018-01-31
DK2544657T3 (da) 2014-08-11
US10085970B2 (en) 2018-10-02
ES2665418T3 (es) 2018-04-25
CA2792392A1 (en) 2011-09-15
DK2567690T3 (da) 2014-08-11
RS53467B (en) 2014-12-31
JP2016028090A (ja) 2016-02-25
PL2567690T3 (pl) 2014-11-28
HK1179152A1 (zh) 2013-09-27
US8686019B2 (en) 2014-04-01
CY1115487T1 (el) 2017-01-04
PT2544657E (pt) 2014-09-03
SMT201400126B (it) 2015-05-05
US20210228543A1 (en) 2021-07-29
MX370629B (es) 2019-12-18
US9084765B2 (en) 2015-07-21
HRP20180436T1 (hr) 2018-05-04
HUE037088T2 (hu) 2018-08-28

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