NL8403634A - Nieuwe azabicyclische verbindingen en een werkwijze voor de bereiding daarvan. - Google Patents

Nieuwe azabicyclische verbindingen en een werkwijze voor de bereiding daarvan. Download PDF

Info

Publication number
NL8403634A
NL8403634A NL8403634A NL8403634A NL8403634A NL 8403634 A NL8403634 A NL 8403634A NL 8403634 A NL8403634 A NL 8403634A NL 8403634 A NL8403634 A NL 8403634A NL 8403634 A NL8403634 A NL 8403634A
Authority
NL
Netherlands
Prior art keywords
general formula
group
formula
optionally
azabicyclo
Prior art date
Application number
NL8403634A
Other languages
English (en)
Dutch (nl)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of NL8403634A publication Critical patent/NL8403634A/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NL8403634A 1983-11-30 1984-11-29 Nieuwe azabicyclische verbindingen en een werkwijze voor de bereiding daarvan. NL8403634A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU834096A HU190511B (en) 1983-11-30 1983-11-30 Process for preparing new azabicyclic compounds
HU409683 1983-11-30

Publications (1)

Publication Number Publication Date
NL8403634A true NL8403634A (nl) 1985-06-17

Family

ID=10966876

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8403634A NL8403634A (nl) 1983-11-30 1984-11-29 Nieuwe azabicyclische verbindingen en een werkwijze voor de bereiding daarvan.

Country Status (31)

Country Link
US (1) US4769373A (de)
JP (1) JPS60185766A (de)
AR (1) AR241492A1 (de)
AT (1) AT388730B (de)
AU (1) AU570285B2 (de)
BE (1) BE901174A (de)
CA (1) CA1280751C (de)
CH (1) CH663615A5 (de)
CS (1) CS273602B2 (de)
DD (1) DD231073A1 (de)
DE (1) DE3442365A1 (de)
DK (1) DK568584A (de)
EG (1) EG16845A (de)
ES (2) ES8604579A1 (de)
FI (1) FI80445C (de)
FR (1) FR2555580B1 (de)
GB (1) GB2150558B (de)
GR (1) GR81084B (de)
HU (1) HU190511B (de)
IL (1) IL73421A (de)
IT (1) IT1178638B (de)
MX (1) MX157611A (de)
NL (1) NL8403634A (de)
NO (1) NO165292C (de)
PH (1) PH19659A (de)
PL (2) PL142604B1 (de)
PT (1) PT79568B (de)
SE (1) SE460418B (de)
SU (1) SU1395141A3 (de)
YU (1) YU45681B (de)
ZA (1) ZA848721B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0525672D0 (en) * 2005-12-16 2006-01-25 Novartis Ag Organic compounds
CN111187210B (zh) * 2020-01-08 2022-05-03 成都中医药大学 一种热解型二萜生物碱化合物及其制备方法和用途
CN113149905B (zh) * 2021-02-24 2022-04-29 成都中医药大学 一种抗心律失常的化合物及其制药用途
CN113149906B (zh) * 2021-02-24 2022-05-17 成都中医药大学 一种抗心律失常药物及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1195746A (en) * 1967-06-07 1970-06-24 Yoshitomi Pharmaceutical 3-Azabicyclo [3,3,1] Nonane Derivatives
US3741973A (en) * 1967-09-11 1973-06-26 Upjohn Co Oxygenated 3-azabicyclo(3.3.1)nonanes
GB1393253A (en) * 1971-09-10 1975-05-07 Wyeth John & Brother Ltd 3-azabicyclo-3,3,1-nonanes

Also Published As

Publication number Publication date
CA1280751C (en) 1991-02-26
ZA848721B (en) 1985-06-26
CH663615A5 (de) 1987-12-31
FI80445C (fi) 1990-06-11
DD231073A1 (de) 1985-12-18
GB8428143D0 (en) 1984-12-12
SE8406046L (sv) 1985-05-31
IT8423805A0 (it) 1984-11-29
HU190511B (en) 1986-09-29
ES8606338A1 (es) 1986-04-01
YU200684A (en) 1987-10-31
NO844750L (no) 1985-05-31
PL254457A1 (en) 1987-03-23
DK568584D0 (da) 1984-11-29
PL250635A1 (en) 1985-11-05
IL73421A (en) 1987-12-31
DE3442365A1 (de) 1985-06-05
FI844480L (fi) 1985-05-31
GR81084B (en) 1985-03-29
FI80445B (fi) 1990-02-28
IT1178638B (it) 1987-09-09
BE901174A (fr) 1985-05-30
HUT35647A (en) 1985-07-29
PL144546B1 (en) 1988-06-30
FR2555580A1 (fr) 1985-05-31
NO165292C (no) 1991-01-23
SU1395141A3 (ru) 1988-05-07
AR241492A1 (es) 1992-07-31
DK568584A (da) 1985-05-31
MX157611A (es) 1988-12-05
SE460418B (sv) 1989-10-09
ATA352184A (de) 1989-01-15
SE8406046D0 (sv) 1984-11-29
ES548112A0 (es) 1986-04-01
CS273602B2 (en) 1991-03-12
PH19659A (en) 1986-06-09
AT388730B (de) 1989-08-25
PT79568A (en) 1984-12-01
EG16845A (en) 1990-12-30
AU3602984A (en) 1985-06-06
PL142604B1 (en) 1987-11-30
AU570285B2 (en) 1988-03-10
JPS60185766A (ja) 1985-09-21
PT79568B (en) 1986-09-11
US4769373A (en) 1988-09-06
GB2150558B (en) 1987-10-14
NO165292B (no) 1990-10-15
GB2150558A (en) 1985-07-03
YU45681B (sh) 1992-07-20
ES538069A0 (es) 1986-02-01
ES8604579A1 (es) 1986-02-01
CS920184A2 (en) 1990-08-14
FI844480A0 (fi) 1984-11-15
FR2555580B1 (fr) 1988-10-28

Similar Documents

Publication Publication Date Title
AU2001256509B2 (en) Cyclohexane derivatives and their use as therapeutic agents
US20020119973A1 (en) Chemokine receptor antagonists and methods of use therefor
US4879300A (en) Novel piperidine derivatives
EP2546256A2 (de) Verfahren zur Synthese von Zwischenprodukten der Herstellung von E1-aktivitätsaktivierenden Enzymhemmern
BG60472B2 (bg) Производни на 1-(циклохексил или циклохексенил)-4-арил-4- пиперидинкарбоксилова киселина
WO2000020390A1 (en) Monomeric and dimeric heterocycles, and therapeutic uses thereof
NL8403634A (nl) Nieuwe azabicyclische verbindingen en een werkwijze voor de bereiding daarvan.
EP2183219A2 (de) N-piperidin-4-ylmethyl-amidderivate und ihre verwendung als monoamin-neurotransmitter-wiederaufnahmehemmer
EP0657455A1 (de) Epi-epibatidinederivate, Verfahren und Zwischenprodukte für ihre Herstellung und Epi-epibatidine und die Epi-epibatidinederivate enthaltende Arzneimittel und/oder Epi-epibatidine und ihre Verwendung
JPH0352465B2 (de)
Diamond et al. Synthesis and properties of the analgesic DL-α-1, 3-dimethyl-4-phenyl-4-propionoxyazacycloheptane (Proheptazine)
CA1328106C (en) Anticholinergic compounds, pharmaceutical compositions and method of treatment
DE69818988T2 (de) 9,10-diazatryclo[4.2.11 2,5]decan- und 9,10-diazatricyclo[3.3.1.1 2,6]decanderive mit analgetischer wirkung
US4617305A (en) 4-alkylindolonaphthyridines and their therapeutical application
JP3047112B2 (ja) 置換アリールアミン類およびヘテロアリールアミン類、それらの製造方法、およびそれらの薬理組成物
CH644364A5 (de) 4-(naphthalinyloxy)piperidin-derivate.
HU191938B (en) Process for production of new derivatives of 9 and 11 nitro-apovincamin acid
AU645685B2 (en) New 1-amidooctahydropyrido(2,1-c)(1,4)oxazine compounds, processes for preparing these and pharmaceutical compositions containing them
SU1095878A3 (ru) Способ получени производных 1-(4-арилциклогексил)пиперидина или их фармацевтически пригодных солей или их стереоизомерных форм
RO115800B1 (ro) Derivat substituit de 1,4-dihidropiridina, procedeu de obtinere, intermediar in sinteza acestuia si compozitie care il contine
Lin et al. The synthesis of 4‐methyl‐2‐pyrrolidones and 3‐methyl‐1‐pyrrolidines and their mass spectral study
CS273650B2 (en) Preparation of new derivatives azabicyclo-/3,3,1/nonane
Nakatani et al. Synthesis of optically active bis (1-mesitylethyl) ethers.
Beitchman et al. New route to isogranatanine derivatives
IL44765A (en) 3-substituted 6,7-diaza-(3,2,2)-bicyclononane derivatives

Legal Events

Date Code Title Description
BV The patent application has lapsed