NL8103751A - 7-beta-(alfa-syn-methoxyimino-alfa-(2-aminothiazol-4yl)aceetamido)-3-((1,2,3-thiazol-5-ylthio)methyl)-3cefem-4-carbonzuur en alkylderivaten daarvan. - Google Patents

7-beta-(alfa-syn-methoxyimino-alfa-(2-aminothiazol-4yl)aceetamido)-3-((1,2,3-thiazol-5-ylthio)methyl)-3cefem-4-carbonzuur en alkylderivaten daarvan. Download PDF

Info

Publication number
NL8103751A
NL8103751A NL8103751A NL8103751A NL8103751A NL 8103751 A NL8103751 A NL 8103751A NL 8103751 A NL8103751 A NL 8103751A NL 8103751 A NL8103751 A NL 8103751A NL 8103751 A NL8103751 A NL 8103751A
Authority
NL
Netherlands
Prior art keywords
compound
formula
methyl
syn
ylthio
Prior art date
Application number
NL8103751A
Other languages
English (en)
Dutch (nl)
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NL8103751A publication Critical patent/NL8103751A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8103751A 1980-08-11 1981-08-10 7-beta-(alfa-syn-methoxyimino-alfa-(2-aminothiazol-4yl)aceetamido)-3-((1,2,3-thiazol-5-ylthio)methyl)-3cefem-4-carbonzuur en alkylderivaten daarvan. NL8103751A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17688980A 1980-08-11 1980-08-11
US17688980 1980-08-11
US06/281,438 US4399132A (en) 1980-08-11 1981-07-08 7-Beta-[alpha-syn-methoxyimino-alpha-(2-aminothiazol-4-yl)-acetamido]-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid and C1 -C6 alkyl derivatives thereof
US28143881 1981-07-08

Publications (1)

Publication Number Publication Date
NL8103751A true NL8103751A (nl) 1982-03-01

Family

ID=26872715

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8103751A NL8103751A (nl) 1980-08-11 1981-08-10 7-beta-(alfa-syn-methoxyimino-alfa-(2-aminothiazol-4yl)aceetamido)-3-((1,2,3-thiazol-5-ylthio)methyl)-3cefem-4-carbonzuur en alkylderivaten daarvan.

Country Status (25)

Country Link
US (1) US4399132A (ja)
JP (1) JPS5759895A (ja)
KR (1) KR840002163B1 (ja)
AR (1) AR228869A1 (ja)
AT (1) AT389639B (ja)
AU (1) AU545895B2 (ja)
BE (1) BE889913A (ja)
CA (1) CA1175417A (ja)
CH (1) CH648561A5 (ja)
DD (1) DD202164A5 (ja)
DE (1) DE3130404A1 (ja)
DK (1) DK155945C (ja)
FI (1) FI74020C (ja)
FR (1) FR2488258A1 (ja)
GB (1) GB2083461B (ja)
GR (1) GR75676B (ja)
HK (1) HK52089A (ja)
HU (1) HU185644B (ja)
IE (1) IE51486B1 (ja)
IL (1) IL63531A (ja)
NL (1) NL8103751A (ja)
NO (1) NO161566C (ja)
NZ (1) NZ197965A (ja)
PL (1) PL131457B1 (ja)
SE (1) SE452324B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60120886A (ja) * 1983-12-02 1985-06-28 Takeda Chem Ind Ltd セフェムカルボン酸のナトリウム塩の結晶
US4914091A (en) * 1984-04-02 1990-04-03 American Cyanamid Company Esters of cephalosporin derivitives
DE3775798D1 (de) 1986-03-19 1992-02-20 Banyu Pharma Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und antibakterielle mittel.
US4927922A (en) * 1986-07-08 1990-05-22 American Cyanamid Company 7β-(substituted)amino-3-substituted cephalosporanic acids and esters
EP0252473A3 (en) * 1986-07-08 1989-07-05 American Cyanamid Company 7 beta-(substituted) amino-3-substituted cephalosporanic acids and esters
US5066799A (en) * 1986-07-28 1991-11-19 American Cyanamid Company Intermediates for the preparation of aminothiazoloximino cephalosporins
EP0257275A3 (en) * 1986-07-28 1990-05-23 American Cyanamid Company Cephalosporin and penicillin derivatives
JPH01230547A (ja) * 1988-01-14 1989-09-14 Takeda Chem Ind Ltd ３−オキソ酪酸第三ブチルの製造法及びその用途
AT394196B (de) * 1990-01-22 1992-02-10 Biochemie Gmbh (6r,7r)-7-((2-(2-amino-4-thiazolyl) -2oxoacetamido)-3-(1,2,3-thiadiazol-5-yl)thiomethyl-3-cephem-4-carbons|urenitrat
CN105646538B (zh) * 2016-03-09 2018-04-24 上海宁瑞生化技术有限公司 一种头孢唑南的制备工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
JPS597717B2 (ja) * 1976-09-08 1984-02-20 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2760484C2 (ja) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2856404A1 (de) * 1978-12-28 1980-07-17 Dynamit Nobel Ag 1,2,3-thiadiazol-5-yl-thioglycolsaeure, deren derivate sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
DK155945C (da) 1989-12-04
IE51486B1 (en) 1987-01-07
ATA307683A (de) 1989-06-15
NO812701L (no) 1982-02-12
DK155945B (da) 1989-06-05
US4399132A (en) 1983-08-16
IL63531A (en) 1985-07-31
JPS6141517B2 (ja) 1986-09-16
DK355081A (da) 1982-02-12
NZ197965A (en) 1984-03-16
FI74020C (fi) 1987-12-10
HU185644B (en) 1985-03-28
PL131457B1 (en) 1984-11-30
FI812470L (fi) 1982-02-12
AU545895B2 (en) 1985-08-08
FR2488258A1 (fr) 1982-02-12
HK52089A (en) 1989-07-07
NO161566C (no) 1989-08-30
IE811811L (en) 1982-02-11
SE8104771L (sv) 1982-02-12
GR75676B (ja) 1984-08-02
DE3130404C2 (ja) 1990-07-19
BE889913A (fr) 1982-02-10
KR840002163B1 (ko) 1984-11-24
GB2083461A (en) 1982-03-24
SE452324B (sv) 1987-11-23
AU7384881A (en) 1982-02-18
FR2488258B1 (ja) 1984-08-24
AT389639B (de) 1990-01-10
GB2083461B (en) 1984-04-11
IL63531A0 (en) 1981-11-30
DE3130404A1 (de) 1982-06-16
NO161566B (no) 1989-05-22
CA1175417A (en) 1984-10-02
CH648561A5 (ja) 1985-03-29
DD202164A5 (de) 1983-08-31
FI74020B (fi) 1987-08-31
AR228869A1 (es) 1983-04-29
PL232568A1 (en) 1983-06-06
JPS5759895A (en) 1982-04-10
KR830006311A (ko) 1983-09-20

Similar Documents

Publication Publication Date Title
CS209878B2 (en) Method of making the new alcyloxime derivatives of the 7-/2-(2-amino-4-thiazolyl)acetamido/cephalosporan acid
DK159156B (da) Analogifremgangsmaade til fremstilling af (2-(2-aminothiazol-4-yl)-2-(0-substitueret)-oxyiminoacetamido)-7-cephalosporan-syre og fysiologisk acceptable salte deraf
JPS6127989A (ja) セフアロスポリン化合物の製法
NL8103751A (nl) 7-beta-(alfa-syn-methoxyimino-alfa-(2-aminothiazol-4yl)aceetamido)-3-((1,2,3-thiazol-5-ylthio)methyl)-3cefem-4-carbonzuur en alkylderivaten daarvan.
NL8203806A (nl) Door een pyraziniumgroep gesubstitueerde cefalosporinen.
CS236798B2 (en) Processing of cefalosporine
US4018921A (en) Substituted phenylglycylcephalosporins
US4576938A (en) Cephalosporin compound and process for preparing the same
KR100696422B1 (ko) 항생물질로서 사이클릭 아미노구아니딘 치환체를 가진세팔로스포린
US4117125A (en) 7-Acylamino-3-[1-[2-(carboxymethylamino]ethyl) tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
US3953439A (en) Substituted phenylglycylcephalosporins
US4311842A (en) Cephalosporin compounds
US4144241A (en) 5-Sulfomethyl-1,3,4-thiadiazole-2-thiol
US4092480A (en) Intermediates for preparing substituted phenylglycylcephalosporins
IL46040A (en) 7(5,6-dihydro-1,4-dithin or oxathiin acetamido) cephalosporanic acid derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
US4201781A (en) Substituted 7[s-oxopyrido[2,3-d]pyrimidine carboxamido acetamido]cephalosporins
US4044047A (en) Intermediates for preparing substituted phenylglycylcephalosporins
US4283398A (en) Cephalosporins
US4088761A (en) 3-[(1,3-Dithiin-5-yl)-acetamido]-cephalosporins and antibacterial compositions containing them
US4013764A (en) Pharmaceutical compositions comprising substituted phenylglycylcephalosporins and methods of treating bacterial infections
US4022895A (en) Substituted phenylglycylcephalosporins
JPS58210093A (ja) セフアロスポリン抗生物質
JPS60163816A (ja) 抗菌剤
JPS63264488A (ja) セファロスポリン化合物
CS209879B2 (cs) Způsob výroby nových alkyloximových derivátů kyseliny 7- [ 2- (2-amíno-4-thiazolyljacetamido] cefalosporanové

Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed