NL301257I2 - cedazuridine of een farmaceutisch aanvaardbaar zout daarvan en decitabine - Google Patents

cedazuridine of een farmaceutisch aanvaardbaar zout daarvan en decitabine

Info

Publication number
NL301257I2
NL301257I2 NL301257C NL301257C NL301257I2 NL 301257 I2 NL301257 I2 NL 301257I2 NL 301257 C NL301257 C NL 301257C NL 301257 C NL301257 C NL 301257C NL 301257 I2 NL301257 I2 NL 301257I2
Authority
NL
Netherlands
Prior art keywords
cedazuridine
decitabine
pharmaceutically acceptable
acceptable salt
salt
Prior art date
Application number
NL301257C
Other languages
English (en)
Dutch (nl)
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40251685&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL301257(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NL301257I2 publication Critical patent/NL301257I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NL301257C 2007-10-16 2023-12-27 cedazuridine of een farmaceutisch aanvaardbaar zout daarvan en decitabine NL301257I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98039707P 2007-10-16 2007-10-16
PCT/US2008/080163 WO2009052287A1 (en) 2007-10-16 2008-10-16 2 ' -flu0r0-2 ' -deoxytetrahydrouridines as cytidine deaminase inhibitors

Publications (1)

Publication Number Publication Date
NL301257I2 true NL301257I2 (nl) 2025-11-06

Family

ID=40251685

Family Applications (2)

Application Number Title Priority Date Filing Date
NL301257C NL301257I2 (nl) 2007-10-16 2023-12-27 cedazuridine of een farmaceutisch aanvaardbaar zout daarvan en decitabine
NL301256C NL301256I2 (nl) 2007-10-16 2023-12-27 cedazuridine, of een farmaceutisch aanvaardbaar zout daarvan

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL301256C NL301256I2 (nl) 2007-10-16 2023-12-27 cedazuridine, of een farmaceutisch aanvaardbaar zout daarvan

Country Status (39)

Country Link
US (4) US8268800B2 (enExample)
EP (2) EP2447272B1 (enExample)
JP (2) JP5496899B2 (enExample)
KR (1) KR101543049B1 (enExample)
CN (1) CN101827856B (enExample)
AT (1) ATE548374T1 (enExample)
BR (1) BRPI0818672B8 (enExample)
CA (1) CA2702274C (enExample)
CO (1) CO6270330A2 (enExample)
CR (1) CR11427A (enExample)
CY (3) CY1112781T1 (enExample)
DK (1) DK2207786T3 (enExample)
EA (1) EA018757B1 (enExample)
EC (1) ECSP10010095A (enExample)
ES (2) ES2384011T3 (enExample)
FI (2) FIC20230039I1 (enExample)
FR (2) FR23C1052I2 (enExample)
GT (1) GT201000088A (enExample)
HR (1) HRP20120419T1 (enExample)
HU (2) HUS2300044I1 (enExample)
IL (1) IL204732A (enExample)
JO (1) JO2778B1 (enExample)
LT (2) LTPA2023539I1 (enExample)
ME (1) ME00997B (enExample)
MX (1) MX2010004109A (enExample)
MY (1) MY147970A (enExample)
NI (1) NI201000055A (enExample)
NL (2) NL301257I2 (enExample)
NO (2) NO2023047I1 (enExample)
NZ (1) NZ584229A (enExample)
PL (1) PL2207786T3 (enExample)
PT (1) PT2207786E (enExample)
RS (1) RS52323B (enExample)
SA (1) SA08290661B1 (enExample)
SI (1) SI2207786T1 (enExample)
TW (1) TWI445539B (enExample)
UA (1) UA99476C2 (enExample)
WO (1) WO2009052287A1 (enExample)
ZA (1) ZA201002178B (enExample)

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Publication number Publication date
US8618075B2 (en) 2013-12-31
KR101543049B1 (ko) 2015-08-07
AU2008312435A8 (en) 2014-07-24
SA08290661B1 (ar) 2012-06-10
GT201000088A (es) 2012-03-13
US8268800B2 (en) 2012-09-18
CA2702274C (en) 2015-12-29
BRPI0818672A2 (pt) 2015-04-14
JP2014177455A (ja) 2014-09-25
ATE548374T1 (de) 2012-03-15
US20090137521A1 (en) 2009-05-28
NL301256I1 (enExample) 2024-01-03
FR23C1052I1 (fr) 2024-01-26
NZ584229A (en) 2012-06-29
EP2207786B1 (en) 2012-03-07
CO6270330A2 (es) 2011-04-20
JO2778B1 (en) 2014-03-15
ES2384011T3 (es) 2012-06-28
FR23C1051I2 (fr) 2025-02-07
EP2447272B1 (en) 2017-02-01
US20140186335A1 (en) 2014-07-03
FIC20230040I1 (fi) 2023-12-22
BRPI0818672B8 (pt) 2021-05-25
ES2616566T3 (es) 2017-06-13
BRPI0818672B1 (pt) 2020-10-20
LTPA2023539I1 (enExample) 2024-02-26
MX2010004109A (es) 2010-08-10
HRP20120419T1 (hr) 2012-07-31
LTC2207786I2 (enExample) 2025-09-10
JP2011500713A (ja) 2011-01-06
TW200924786A (en) 2009-06-16
NI201000055A (es) 2010-08-13
NO2023048I1 (en) 2023-12-21
IL204732A0 (en) 2010-11-30
LTPA2023538I1 (enExample) 2024-02-26
KR20100091978A (ko) 2010-08-19
NL301256I2 (nl) 2024-01-11
TWI445539B (zh) 2014-07-21
CN101827856A (zh) 2010-09-08
US20120289475A1 (en) 2012-11-15
NO2023047I1 (no) 2023-12-21
AU2008312435B2 (en) 2014-04-17
CN101827856B (zh) 2013-02-06
FIC20230039I1 (fi) 2023-12-22
US8951987B2 (en) 2015-02-10
CY2023029I1 (el) 2024-02-16
FR23C1051I1 (fr) 2024-01-26
DK2207786T3 (da) 2012-06-18
EP2207786A1 (en) 2010-07-21
AU2008312435A1 (en) 2009-04-23
FR23C1052I2 (fr) 2025-02-07
RS52323B (sr) 2012-12-31
CY1112781T1 (el) 2016-02-10
ZA201002178B (en) 2011-05-25
US9567363B2 (en) 2017-02-14
CA2702274A1 (en) 2009-04-23
MY147970A (en) 2013-02-28
UA99476C2 (en) 2012-08-27
EA018757B1 (ru) 2013-10-30
US20150210730A1 (en) 2015-07-30
IL204732A (en) 2013-07-31
PT2207786E (pt) 2012-05-28
EA201000642A1 (ru) 2010-10-29
HUS2300044I1 (hu) 2024-01-28
HK1146410A1 (en) 2011-06-03
CY2023028I1 (el) 2024-02-16
JP5859588B2 (ja) 2016-02-10
ME00997B (me) 2012-10-20
PL2207786T3 (pl) 2012-09-28
WO2009052287A1 (en) 2009-04-23
ECSP10010095A (es) 2010-07-30
HUS2300045I1 (hu) 2024-01-28
SI2207786T1 (sl) 2012-10-30
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CR11427A (es) 2010-08-16
JP5496899B2 (ja) 2014-05-21

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