NL194982C - Neutrofiel-activerende factor (NAF) in geïsoleerde vorm, werkwijze voor het bereiden van NAF, expressievector met een codering voor NAF en een NAF bevattend farmaceutisch preparaat. - Google Patents

Neutrofiel-activerende factor (NAF) in geïsoleerde vorm, werkwijze voor het bereiden van NAF, expressievector met een codering voor NAF en een NAF bevattend farmaceutisch preparaat. Download PDF

Info

Publication number
NL194982C
NL194982C NL8820928A NL8820928A NL194982C NL 194982 C NL194982 C NL 194982C NL 8820928 A NL8820928 A NL 8820928A NL 8820928 A NL8820928 A NL 8820928A NL 194982 C NL194982 C NL 194982C
Authority
NL
Netherlands
Prior art keywords
naf
lys
glu
leu
arg
Prior art date
Application number
NL8820928A
Other languages
English (en)
Dutch (nl)
Other versions
NL8820928A (nl
Original Assignee
Novartis Ag
Kocher Theodor Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27263673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL194982(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878727053A external-priority patent/GB8727053D0/en
Priority claimed from GB888805070A external-priority patent/GB8805070D0/en
Priority claimed from GB888825258A external-priority patent/GB8825258D0/en
Application filed by Novartis Ag, Kocher Theodor Inst filed Critical Novartis Ag
Publication of NL8820928A publication Critical patent/NL8820928A/nl
Application granted granted Critical
Publication of NL194982C publication Critical patent/NL194982C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5421—IL-8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NL8820928A 1987-11-19 1988-11-12 Neutrofiel-activerende factor (NAF) in geïsoleerde vorm, werkwijze voor het bereiden van NAF, expressievector met een codering voor NAF en een NAF bevattend farmaceutisch preparaat. NL194982C (nl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB878727053A GB8727053D0 (en) 1987-11-19 1987-11-19 Neutrophil-activating factor(naf)
GB888805070A GB8805070D0 (en) 1988-03-03 1988-03-03 Neutrophil-activating factor(naf)
GB8805070 1988-10-28
GB8825258 1988-10-28
GB888825258A GB8825258D0 (en) 1988-10-28 1988-10-28 Neutrophil-activating factor
GB8727053 1988-10-28

Publications (2)

Publication Number Publication Date
NL8820928A NL8820928A (nl) 1989-10-02
NL194982C true NL194982C (nl) 2003-04-10

Family

ID=27263673

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8820928A NL194982C (nl) 1987-11-19 1988-11-12 Neutrofiel-activerende factor (NAF) in geïsoleerde vorm, werkwijze voor het bereiden van NAF, expressievector met een codering voor NAF en een NAF bevattend farmaceutisch preparaat.

Country Status (23)

Country Link
US (1) US6383479B1 (fr)
JP (1) JP3133305B2 (fr)
KR (1) KR890701625A (fr)
AT (1) ATA901588A (fr)
AU (1) AU622125B2 (fr)
BE (1) BE1001817A5 (fr)
CH (1) CH680001A5 (fr)
DE (2) DE3890998T1 (fr)
DK (1) DK354389A (fr)
ES (1) ES2014546A6 (fr)
FI (1) FI893474A (fr)
FR (1) FR2623400B1 (fr)
GB (1) GB2223225B (fr)
GR (1) GR880100775A (fr)
HU (1) HU205617B (fr)
IL (1) IL88404A0 (fr)
IT (1) IT1224574B (fr)
NL (1) NL194982C (fr)
NZ (1) NZ226990A (fr)
PL (1) PL275881A1 (fr)
PT (1) PT89026B (fr)
SE (1) SE8902507D0 (fr)
WO (1) WO1989004836A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652338A (en) 1988-03-16 1997-07-29 The United States Of America As Represented By The Department Of Health And Human Services Neutrophil chemotactic factor
EP0423193A4 (en) * 1988-07-07 1991-10-16 United States Government, As Represented By The Department Of Health & Human Services A method of treating diseases caused by immunodeficiency states by administering human neutrophil chemotactic factor to human
WO1990001338A1 (fr) * 1988-08-15 1990-02-22 Brigham And Women's Hospital Inhibiteur d'adhesion de leucocytes
KR100197110B1 (ko) * 1988-08-29 1999-06-15 로버트 란만 활성 사람 호중구 화학주성 인자 폴리펩티드의 제조방법
JP2844260B2 (ja) * 1988-11-10 1999-01-06 ステファン チャールズ マックケイブ シャワーヘッド組立体
US5241049A (en) * 1989-12-22 1993-08-31 Zymogenetics, Inc. Neutrophil chemoattractants
US5079228A (en) * 1990-02-05 1992-01-07 Board Of Regents, The University Of Texas System Peptide inhibitors of neutrophil activating factor induced chemotaxis
IE913192A1 (en) * 1990-09-12 1992-02-25 Scripps Research Inst Active site of interleukin-8: polypeptide analogs and¹antibodies
WO1993001826A1 (fr) * 1991-07-19 1993-02-04 East Carolina University Methode de traitement de l'asthme
US5401651A (en) * 1991-10-16 1995-03-28 Walz; Alfred DNA encoding ENA-78, a neutrophil activating factor
GB9124775D0 (en) * 1991-11-21 1992-01-15 Medical Res Council Cervical ripening
US5665346A (en) * 1991-12-04 1997-09-09 Research Corporation Technologies, Inc. Human interleukin-8 analogs
GB9807721D0 (en) * 1998-04-08 1998-06-10 Chiron Spa Antigen
CN114391095A (zh) * 2019-06-27 2022-04-22 比纳瑞有限责任公司 适用于即时(poc)诊断测试绝对嗜中性粒细胞功能(anf)的即时(poc)测量的全血和体液中吞噬性白细胞的基于氧化酶的化学发光测定

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3737703A1 (de) * 1987-11-06 1989-05-18 Ferring Arzneimittel Gmbh Neutrophilen aktivierendes polypeptid, verfahren zu dessen herstellung sowie dessen verwendung als arzneimittel und diagnostikum
US5652338A (en) * 1988-03-16 1997-07-29 The United States Of America As Represented By The Department Of Health And Human Services Neutrophil chemotactic factor
EP0413818B1 (fr) 1988-05-02 1994-12-28 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY of the DEPARTMENT OF HEALTH AND HUMAN SERVICES Procede de production d'un polypeptide du facteur chimiotactique neutrophile humain
WO1990001338A1 (fr) 1988-08-15 1990-02-22 Brigham And Women's Hospital Inhibiteur d'adhesion de leucocytes
AU4665689A (en) * 1989-12-11 1991-07-18 Wallac Oy Elastic scintillator material

Also Published As

Publication number Publication date
FI893474A0 (fi) 1989-07-18
IL88404A0 (en) 1989-06-30
ES2014546A6 (es) 1990-07-16
FR2623400A1 (fr) 1989-05-26
GB2223225B (en) 1992-07-08
GR880100775A (el) 1994-03-31
US6383479B1 (en) 2002-05-07
WO1989004836A1 (fr) 1989-06-01
AU2716288A (en) 1989-06-14
FI893474A (fi) 1989-07-18
FR2623400B1 (fr) 1995-06-23
NZ226990A (en) 1991-10-25
AU622125B2 (en) 1992-04-02
NL8820928A (nl) 1989-10-02
BE1001817A5 (fr) 1990-03-13
HUT52551A (en) 1990-07-28
SE8902507L (sv) 1989-07-11
SE8902507D0 (sv) 1989-07-11
HU886790D0 (en) 1990-01-28
JPH02502825A (ja) 1990-09-06
DK354389A (da) 1989-09-19
PT89026A (pt) 1988-12-01
IT8848572A0 (it) 1988-11-18
IT1224574B (it) 1990-10-04
PL275881A1 (en) 1989-07-24
DE3890998B4 (de) 2008-01-03
GB2223225A (en) 1990-04-04
JP3133305B2 (ja) 2001-02-05
HU205617B (en) 1992-05-28
GB8913271D0 (en) 1989-12-06
KR890701625A (ko) 1989-12-21
CH680001A5 (fr) 1992-05-29
PT89026B (pt) 1993-02-26
DK354389D0 (da) 1989-07-18
ATA901588A (de) 1994-07-15
DE3890998T1 (de) 1991-02-21

Similar Documents

Publication Publication Date Title
NL194982C (nl) Neutrofiel-activerende factor (NAF) in geïsoleerde vorm, werkwijze voor het bereiden van NAF, expressievector met een codering voor NAF en een NAF bevattend farmaceutisch preparaat.
KR920010225B1 (ko) 인간암괴사인자 및 그를 코우드하는 dna의 제법
JP2553829B2 (ja) 組換えコロニー刺激因子−１
AU2005323392B2 (en) Use of IL-22 for the treatment of conditions of metabolic disorders
EP0256843A1 (fr) Expression de G-CSF et des mutéines de celui-ci et leur utilisation
JP2667193B2 (ja) 二機能性タンパク質
JPH02194A (ja) ヒト血清アルブミンのｎ‐未端を含有するポリペプチド
DK163187B (da) Fremgangsmaader til fremstilling af humant immuninterferon (gamma-interferon) samt dna-fragmenter, rekombinante klonings- og udtrykkelsesvektorer og rekombinante mikroorganismer og cellekulturer til anvendelse herved
JPH01501283A (ja) 新規な型のコロニー刺激因子―１
WO2003062273A2 (fr) Traitement medical
ITFI940106A1 (it) Molecola ibrida di formula gm-csf-l-epo o epo-l-gm-csf per la stimolaz ione eritropoietica
JPH0866194A (ja) ヒト腫瘍壊死因子ミューテインをコードする遺伝子
JPH09512423A (ja) エラスターゼ阻害活性を有するα−１−アンチキモトリプシンアナログ
KR20030034238A (ko) 다발성 경화증의 치료에서 사용되는 케모킨 변이체
JPS635099A (ja) 新規なポリペプチド、その製法及び用途
US5306627A (en) Process for producing a human neutrophil chemotactic factor peptide and a recombinant expression vector for the said polypeptide
Gonnelli et al. Purification and characterization of two leaf polypeptide inhibitors of leaf protease from alfalfa (Medicago sativa)
Gase et al. Critical role of the C-terminus in the biological activities of human tumour necrosis factor-alpha
JP2696316B2 (ja) ヒルジンの発現のためのベクター、形質転換細胞及びヒルジンの製造方法
KR100525348B1 (ko) 내열 안정성 안티트롬빈 변이체
EP0686194A1 (fr) Facteurs de croissance de la famille de l'harp, procede d'obtention et applications
EP0609242A1 (fr) Nouvelle proteine inhibitrice de la thrombine provenant de tiques.
CA2524270A1 (fr) Procede de production d'un facteur chimiotactique a domaine n-terminal modifie
JPH1156368A (ja) 猫トロンボポエチンの活性を有する因子
Zang et al. A novel thrombopoietin–stem‐cell factor fusion protein possesses enhanced potential in stimulating megakaryocyte proliferation and differentiation

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: THEODOR KOCHER INSTITUT;NOVARTIS AG

NP1 Patent granted (not automatically)
V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20081112