MXPA04003936A - Cristal en forma alfa o en forma beta de derivado de acetanilida. - Google Patents

Cristal en forma alfa o en forma beta de derivado de acetanilida.

Info

Publication number
MXPA04003936A
MXPA04003936A MXPA04003936A MXPA04003936A MXPA04003936A MX PA04003936 A MXPA04003936 A MX PA04003936A MX PA04003936 A MXPA04003936 A MX PA04003936A MX PA04003936 A MXPA04003936 A MX PA04003936A MX PA04003936 A MXPA04003936 A MX PA04003936A
Authority
MX
Mexico
Prior art keywords
crystal
alpha
useful
acetanilide
form crystal
Prior art date
Application number
MXPA04003936A
Other languages
English (en)
Inventor
Maruyama Tatsuya
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19148268&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA04003936(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of MXPA04003936A publication Critical patent/MXPA04003936A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

Cristales novedosos utiles como un material de partida para un remedio de la diabetes. Estos son cristales en forma a y en forma ?? de (R) -2-(2-aminotiazol) -4-il) -4Æ-(2-((2 -hidroxi-2 -feniletil)amino) etil)acetamida. El cristal en forma a no tiene higroscopicidad, tiene estabilidad que hace al cristal utilizable en un medicamento, y es util para la sintesis en masas en la produccion industrial el cristal en forma ?? tiene higroscopicidad relativamente baja y es util tambien como un intermediario para el cristal en forma a.
MXPA04003936A 2001-10-30 2002-10-29 Cristal en forma alfa o en forma beta de derivado de acetanilida. MXPA04003936A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001332914 2001-10-30
PCT/JP2002/011217 WO2003037881A1 (fr) 2001-10-30 2002-10-29 Cristal a forme $g(a) ou $g(b) d'un derive acetanilinide

Publications (1)

Publication Number Publication Date
MXPA04003936A true MXPA04003936A (es) 2004-06-18

Family

ID=19148268

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04003936A MXPA04003936A (es) 2001-10-30 2002-10-29 Cristal en forma alfa o en forma beta de derivado de acetanilida.

Country Status (17)

Country Link
US (2) US7342117B2 (es)
EP (3) EP1932838A3 (es)
JP (1) JP3800220B2 (es)
KR (1) KR100908796B1 (es)
CN (1) CN1243740C (es)
AU (1) AU2002344419C1 (es)
BR (1) BRPI0213570B8 (es)
CA (1) CA2464068C (es)
ES (1) ES2404071T3 (es)
HU (1) HU230481B1 (es)
MX (1) MXPA04003936A (es)
NO (1) NO326965B1 (es)
PL (1) PL218982B1 (es)
RU (1) RU2303033C2 (es)
TW (1) TW200300020A (es)
WO (1) WO2003037881A1 (es)
ZA (1) ZA200403044B (es)

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KR20200117091A (ko) 2019-04-02 2020-10-14 제이투에이치바이오텍 (주) 미라베그론 전구체 약물 화합물 및 이의 과민성 방광 질환의 치료 또는 개선을 위한 의약 용도
CN110590699B (zh) * 2019-09-29 2022-11-15 广东先强药业有限公司 一种米拉贝隆的精制方法
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CN113816864B (zh) * 2020-06-18 2024-03-29 南京正大天晴制药有限公司 一种(r)-2-羟基-n-[2-(4-氨基苯基)乙基]-2-苯乙胺的制备方法
CN114539182B (zh) * 2020-11-24 2024-08-09 威智医药股份有限公司 转晶溶剂及其应用和米拉贝隆α晶型的制备方法
CN114539084B (zh) * 2020-11-24 2024-04-02 威智医药股份有限公司 米拉贝隆及其中间体的制备方法
KR20220081033A (ko) 2020-12-08 2022-06-15 주식회사 한서켐 미라베그론 α형 결정의 제조방법
CN112574137A (zh) * 2021-01-19 2021-03-30 南京美瑞制药有限公司 一种α晶型米拉贝隆的制备方法
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Also Published As

Publication number Publication date
KR20050040837A (ko) 2005-05-03
US20050004190A1 (en) 2005-01-06
US7982049B2 (en) 2011-07-19
PL369874A1 (en) 2005-05-02
NO326965B1 (no) 2009-03-23
EP1932838A2 (en) 2008-06-18
US7342117B2 (en) 2008-03-11
KR100908796B1 (ko) 2009-07-22
EP1932838A3 (en) 2008-07-30
PL218982B1 (pl) 2015-02-27
RU2303033C2 (ru) 2007-07-20
HUP0401665A1 (hu) 2004-11-29
HU230481B1 (hu) 2016-07-28
BRPI0213570B8 (pt) 2021-05-25
EP2298752B1 (en) 2013-03-27
CN1575287A (zh) 2005-02-02
BR0213570A (pt) 2004-10-26
US20080214633A1 (en) 2008-09-04
CA2464068A1 (en) 2003-05-08
NO20042227L (no) 2004-05-28
CA2464068C (en) 2007-10-16
JP3800220B2 (ja) 2006-07-26
ZA200403044B (en) 2005-06-29
EP1440969A4 (en) 2005-01-19
KR100908796B9 (ko) 2024-07-17
JPWO2003037881A1 (ja) 2005-02-17
BRPI0213570B1 (pt) 2018-02-27
EP1440969A1 (en) 2004-07-28
EP2298752A1 (en) 2011-03-23
AU2002344419C1 (en) 2024-02-01
WO2003037881A1 (fr) 2003-05-08
CN1243740C (zh) 2006-03-01
AU2002344419B2 (en) 2007-12-13
ES2404071T3 (es) 2013-05-23
HUP0401665A3 (en) 2008-05-28
TWI322805B (es) 2010-04-01
RU2004116313A (ru) 2005-03-27
TW200300020A (en) 2003-05-01

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