MX9604434A - Productos farmaceuticos y medicamentos para la prevencion y el tratamiento de disfunciones endoteliales. - Google Patents
Productos farmaceuticos y medicamentos para la prevencion y el tratamiento de disfunciones endoteliales.Info
- Publication number
- MX9604434A MX9604434A MX9604434A MX9604434A MX9604434A MX 9604434 A MX9604434 A MX 9604434A MX 9604434 A MX9604434 A MX 9604434A MX 9604434 A MX9604434 A MX 9604434A MX 9604434 A MX9604434 A MX 9604434A
- Authority
- MX
- Mexico
- Prior art keywords
- medicaments
- prevention
- treatment
- pharmaceutical preparations
- endothelial dysfunction
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invencion describe la utilizacion de compuestos liberadores o transmisores de monoxido de nitrogeno, de estimuladores de la formacion endogena de nonoxido de nitrogeno, así como de estimuladores de la guanilatociclasa para la prevencion, el tratamiento y la correccion de disfunciones enodteliales y de enfermedades que van acompañadas de dichas disfunciones o que son ocasionadas por las mismas, así como la utilizacion de los mencionadas compuestos para la fabricacion de productos farmacéuticos para los campos de aplicacion mencionados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4410997A DE4410997A1 (de) | 1994-03-30 | 1994-03-30 | Pharmazeutische Zubereitungen und Arzneistoffe zur Prävention und Behandlung endothelialer Dysfunktionen |
PCT/DE1995/000421 WO1995026725A1 (de) | 1994-03-30 | 1995-03-28 | Pharmazeutische zubereitingen und arzneistoffe zur prävention und behandlung endothelialer dysfunktion |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9604434A true MX9604434A (es) | 1997-12-31 |
Family
ID=6514213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9604434A MX9604434A (es) | 1994-03-30 | 1995-03-28 | Productos farmaceuticos y medicamentos para la prevencion y el tratamiento de disfunciones endoteliales. |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0752858A1 (es) |
JP (1) | JPH09510979A (es) |
CN (1) | CN1150387A (es) |
BG (1) | BG63073B1 (es) |
CA (1) | CA2186783A1 (es) |
CZ (1) | CZ283696A3 (es) |
DE (2) | DE4410997A1 (es) |
EE (1) | EE9600139A (es) |
FI (1) | FI963883A0 (es) |
HU (1) | HU220165B (es) |
IS (1) | IS4365A (es) |
LT (1) | LT4310B (es) |
LV (1) | LV11666B (es) |
MX (1) | MX9604434A (es) |
NO (1) | NO964102L (es) |
PL (1) | PL316528A1 (es) |
SI (1) | SI9520047A (es) |
SK (1) | SK121896A3 (es) |
WO (1) | WO1995026725A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9423868D0 (en) * | 1994-11-25 | 1995-01-11 | Wellcome Found | Compounds for use in medicine |
DE19654895C2 (de) * | 1996-02-07 | 2000-07-27 | Sanol Arznei Schwarz Gmbh | Detektionsverfahren |
DE19604361C2 (de) * | 1996-02-07 | 1999-01-14 | Sanol Arznei Schwarz Gmbh | Verwendung gasdichter Primärpackmittel für pharmazeutische Zusammensetzungen |
DE19726812A1 (de) * | 1997-06-25 | 1999-01-07 | Isis Pharma Gmbh | Neue Derivate des Pentaerythrits, deren Herstellung und Verwendung sowie Intermediate zur Synthese derselben |
US5958926A (en) * | 1996-11-01 | 1999-09-28 | Nitromed, Inc. | Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses |
USRE37234E1 (en) | 1996-11-01 | 2001-06-19 | Nitromed, Inc. | Nitrosated and nitrosylated phosphodiestrase inhibitor compounds, compositions and their uses |
US6331543B1 (en) | 1996-11-01 | 2001-12-18 | Nitromed, Inc. | Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use |
DE19745622A1 (de) * | 1997-10-16 | 1999-04-22 | Isis Pharma Gmbh | Neue Salpetersäureester des Pentaerythrits |
ZA989356B (en) * | 1997-10-16 | 1998-11-16 | Isis Pharma Gmbh | Pharmaceutical preparations |
DK1023067T4 (da) * | 1997-10-17 | 2011-12-12 | Ark Therapeutics Ltd | Anvendelse af inhibitorer af renin-angiotensin-systemet til behandling af hypoxi eller svækket metabolisk funktion |
US6472425B1 (en) | 1997-10-31 | 2002-10-29 | Nitromed, Inc. | Methods for treating female sexual dysfunctions |
AU5503199A (en) * | 1998-06-24 | 2000-01-10 | Alpharma-Isis Gmbh And Co. Kg | Analytic substrates and antioxidative agents |
AU7365900A (en) | 1999-09-08 | 2001-04-10 | Nitromed, Inc. | Methods of treating and preventing congestive heart failure with hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate |
US7235237B2 (en) | 1999-10-29 | 2007-06-26 | Nitromed, Inc. | Methods of treating vascular diseases characterized by nitric oxide insufficiency |
US7537785B2 (en) | 1999-10-29 | 2009-05-26 | Nitromed, Inc. | Composition for treating vascular diseases characterized by nitric oxide insufficiency |
JP2003514020A (ja) | 1999-10-29 | 2003-04-15 | ニトロメド インコーポレーテッド | 酸化窒素不足により特徴付けられる血管疾患の治療法 |
US7708989B2 (en) | 1999-10-29 | 2010-05-04 | Nitromed, Inc. | Methods of treating vascular diseases characterized by nitric oxide insufficiency |
ES2258365B1 (es) * | 2003-10-03 | 2007-12-01 | Lacer, S.A. | Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos. |
WO2008124505A2 (en) * | 2007-04-05 | 2008-10-16 | Ironwood Pharmaceuticals,Inc. | Soluble guanylate cyclase (sgc) modulators for treatment of lipid related disorders |
NZ603884A (en) * | 2010-05-27 | 2014-06-27 | Merck Sharp & Dohme | Soluble guanylate cyclase activators |
RU2467748C1 (ru) * | 2011-08-08 | 2012-11-27 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" | Производное 3-(2,2,2-триметилгидразиний)пропионата - глицинат 3-(2,2,2-триметилгидразиний)пропионат калия, обладающее эндотелиопротекторной активностью |
JP5360939B2 (ja) * | 2011-09-28 | 2013-12-04 | 国立大学法人徳島大学 | ニトロソニフェジピン誘導体を有効成分とする動脈硬化症治療剤 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR984523A (fr) * | 1949-02-10 | 1951-07-06 | Phosphate de trinitro-triéthanolamine et procédé de préparation | |
DE1695897C3 (de) * | 1966-07-04 | 1979-02-15 | Takeda Chemical Industries Ltd | N-Acyl-sydnonimine, deren Salze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
GB1356374A (en) * | 1971-04-29 | 1974-06-12 | American Home Prod | Mononitrate esters of 1,3 3,6-dianhydro-d-glucitol |
US3886186A (en) * | 1971-04-29 | 1975-05-27 | American Home Prod | Mononitrate esters of 1,4:3,6-dianhydro-d-glucitol |
DE2532124C3 (de) * | 1975-07-18 | 1979-04-19 | Cassella Ag, 6000 Frankfurt | Verfahren zur Herstellung von 4-Amino-morpholin |
US4200640A (en) * | 1976-04-02 | 1980-04-29 | Chugai Seiyaku Kabushiki Kaisha | Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use |
DE2623800C3 (de) * | 1976-05-28 | 1978-11-23 | Sanol Schwarz-Monheim Gmbh, 4000 Duesseldorf | Obersättigte wässerige Isosorbiddinitrat-Lösung, Herstellungsverfahren und Verwendung |
US4065488A (en) * | 1977-02-24 | 1977-12-27 | American Home Products Corporation | Process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate |
DE2903927C2 (de) * | 1979-02-02 | 1981-03-12 | Sanol Schwarz-Monheim Gmbh, 4019 Monheim | Verfahren zur selektiven Herstellung von Isosorbid-5-nitrat |
DE3028873C2 (de) * | 1980-07-30 | 1983-10-27 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Herstellung von 1,4 zu 3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat) |
DE3102947A1 (de) * | 1981-01-29 | 1982-09-02 | Heinrich Mack Nachf., 7918 Illertissen | Verfahren zur herstellung von isosorbid-5-nitrat |
FR2500835A1 (fr) * | 1981-02-27 | 1982-09-03 | Poudres & Explosifs Ste Nale | Procede de synthese des mononitrates d'isosorbide |
DE3117612A1 (de) * | 1981-05-05 | 1982-11-25 | Cassella Ag, 6000 Frankfurt | Verfahren zur herstellung von isosorbid-5-nitrat |
DE3124410A1 (de) * | 1981-06-22 | 1983-01-05 | Heinrich Mack Nachf., 7918 Illertissen | Verfahren zur herstellung von isosorbid-2-nitrat |
JPS5910513A (ja) * | 1982-07-12 | 1984-01-20 | Nitto Electric Ind Co Ltd | 医薬製剤 |
DE3325652A1 (de) * | 1983-07-15 | 1985-01-24 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Feste, stabile isosorbid-5-mononitrat enthaltende arzneimittelzubereitungen und verfahren zu ihrer herstellung |
DE3328094A1 (de) * | 1983-08-04 | 1985-02-21 | H. Trommsdorff GmbH & Co, 5110 Alsdorf | Phlegmatisierte pharmazeutische zubereitung von explosionsfaehigen salpetersaeureestern |
DE3479800D1 (en) * | 1983-11-25 | 1989-10-26 | Toshin Chemical Co | A method for the preparation of isosorbide-5-nitrate and sodium isosorbide-5-nitrate hydrate as a precursor thereof |
DD244980A1 (de) * | 1985-12-18 | 1987-04-22 | Isis Chemie Zwickau Veb | Verfahren zur herstellung von n-morpholinoaminoacetonitril und dessen hydrochlorid |
DD293492A5 (de) * | 1987-11-26 | 1991-09-05 | Isis-Chemie Gmbh,De | Verfahren zur herstellung einer glyceroltrinitrat-arzneiform mit gleichmaessig verzoegerter arzneistofffreisetzung |
US5284872A (en) * | 1989-09-12 | 1994-02-08 | Schwarz Pharma Ag | Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof |
DE4007705C1 (es) * | 1990-03-10 | 1991-09-26 | G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De | |
DE4038203A1 (de) * | 1990-11-30 | 1992-06-04 | Kali Chemie Pharma Gmbh | Pharmazeutische spray-zubereitungen mit coronaraktiven wirkstoffen |
US5385937A (en) * | 1991-04-10 | 1995-01-31 | Brigham & Women's Hospital | Nitrosation of homocysteine as a method for treating homocysteinemia |
-
1994
- 1994-03-30 DE DE4410997A patent/DE4410997A1/de not_active Withdrawn
-
1995
- 1995-03-28 SI SI9520047A patent/SI9520047A/sl unknown
- 1995-03-28 EP EP95914275A patent/EP0752858A1/de not_active Withdrawn
- 1995-03-28 MX MX9604434A patent/MX9604434A/es not_active IP Right Cessation
- 1995-03-28 CA CA002186783A patent/CA2186783A1/en not_active Abandoned
- 1995-03-28 PL PL95316528A patent/PL316528A1/xx unknown
- 1995-03-28 CN CN95193401A patent/CN1150387A/zh active Pending
- 1995-03-28 SK SK1218-96A patent/SK121896A3/sk unknown
- 1995-03-28 WO PCT/DE1995/000421 patent/WO1995026725A1/de not_active Application Discontinuation
- 1995-03-28 DE DE19580261T patent/DE19580261D2/de not_active Expired - Lifetime
- 1995-03-28 CZ CZ962836A patent/CZ283696A3/cs unknown
- 1995-03-28 EE EE9600139A patent/EE9600139A/xx unknown
- 1995-03-28 JP JP7525343A patent/JPH09510979A/ja active Pending
- 1995-03-28 HU HU9602671A patent/HU220165B/hu not_active IP Right Cessation
-
1996
- 1996-09-19 LV LVP-96-378A patent/LV11666B/lv unknown
- 1996-09-25 IS IS4365A patent/IS4365A/is unknown
- 1996-09-27 NO NO964102A patent/NO964102L/no not_active Application Discontinuation
- 1996-09-27 FI FI963883A patent/FI963883A0/fi unknown
- 1996-10-22 LT LT96-148A patent/LT4310B/lt not_active IP Right Cessation
- 1996-10-22 BG BG100930A patent/BG63073B1/bg unknown
Also Published As
Publication number | Publication date |
---|---|
CN1150387A (zh) | 1997-05-21 |
HUT76676A (en) | 1997-10-28 |
HU220165B (hu) | 2001-11-28 |
BG100930A (en) | 1997-07-31 |
CZ283696A3 (cs) | 1998-03-18 |
EP0752858A1 (de) | 1997-01-15 |
JPH09510979A (ja) | 1997-11-04 |
LV11666A (lv) | 1997-02-20 |
EE9600139A (et) | 1997-04-15 |
NO964102D0 (no) | 1996-09-27 |
HU9602671D0 (en) | 1996-11-28 |
LT4310B (lt) | 1998-03-25 |
BG63073B1 (bg) | 2001-03-30 |
DE19580261D2 (de) | 1997-05-28 |
SK121896A3 (en) | 1998-10-07 |
WO1995026725A1 (de) | 1995-10-12 |
CA2186783A1 (en) | 1995-10-12 |
AU2134595A (en) | 1995-10-23 |
NO964102L (no) | 1996-09-27 |
FI963883A (fi) | 1996-09-27 |
SI9520047A (en) | 1997-06-30 |
IS4365A (is) | 1996-09-25 |
DE4410997A1 (de) | 1995-10-26 |
PL316528A1 (en) | 1997-01-20 |
FI963883A0 (fi) | 1996-09-27 |
LV11666B (en) | 1997-06-20 |
LT96148A (en) | 1997-12-29 |
AU698359B2 (en) | 1998-10-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
MM | Annulment or lapse due to non-payment of fees |