MX6314E - Procedimiento microbiologico para la preparacion de monacolin k - Google Patents

Procedimiento microbiologico para la preparacion de monacolin k

Info

Publication number
MX6314E
MX6314E MX808652U MX865280U MX6314E MX 6314 E MX6314 E MX 6314E MX 808652 U MX808652 U MX 808652U MX 865280 U MX865280 U MX 865280U MX 6314 E MX6314 E MX 6314E
Authority
MX
Mexico
Prior art keywords
monacolin
preparation
microbiological procedure
microbiological
procedure
Prior art date
Application number
MX808652U
Other languages
English (en)
Inventor
Akira Endo
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of MX6314E publication Critical patent/MX6314E/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
MX808652U 1979-02-20 1980-02-20 Procedimiento microbiologico para la preparacion de monacolin k MX6314E (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54017856A JPS5925599B2 (ja) 1979-02-20 1979-02-20 新生理活性物質モナコリンkおよびその製造法

Publications (1)

Publication Number Publication Date
MX6314E true MX6314E (es) 1985-04-01

Family

ID=11955290

Family Applications (1)

Application Number Title Priority Date Filing Date
MX808652U MX6314E (es) 1979-02-20 1980-02-20 Procedimiento microbiologico para la preparacion de monacolin k

Country Status (27)

Country Link
JP (1) JPS5925599B2 (es)
KR (1) KR830002801B1 (es)
AT (1) AT373915B (es)
AU (1) AU532626B2 (es)
BE (1) BE881825A (es)
CA (1) CA1129794A (es)
CH (1) CH645890A5 (es)
DD (1) DD154494A5 (es)
DE (2) DE3006216C2 (es)
DK (2) DK149095C (es)
ES (1) ES488796A0 (es)
FI (1) FI66427C (es)
FR (1) FR2449685B1 (es)
GB (1) GB2046737B (es)
HU (1) HU182069B (es)
IE (1) IE49743B1 (es)
IT (1) IT1175260B (es)
MX (1) MX6314E (es)
NL (1) NL191540C (es)
NO (1) NO153974C (es)
NZ (1) NZ192919A (es)
PH (1) PH15145A (es)
PL (1) PL124304B1 (es)
SE (1) SE453301B (es)
SG (1) SG6784G (es)
SU (2) SU1158048A3 (es)
ZA (1) ZA80962B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55150898A (en) * 1979-05-11 1980-11-25 Sankyo Co Ltd Preparation of a new physiologically active substance mb-530b
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
JPS5621594A (en) * 1979-07-27 1981-02-28 Sankyo Co Ltd Mb-530b carboxylic acid metal salt and its preparation
PT72394B (en) * 1980-02-04 1982-09-06 Merck & Co Inc Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics
AU548996B2 (en) * 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives
JPH0692381B2 (ja) * 1980-03-31 1994-11-16 三共株式会社 Mb−530a誘導体
JPS56142236A (en) 1980-04-08 1981-11-06 Sankyo Co Ltd Ml-236a and mb-530a derivative
DK149080C (da) * 1980-06-06 1986-07-28 Sankyo Co Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre
JPS5835144A (ja) * 1981-08-27 1983-03-01 Sankyo Co Ltd Mb−530b誘導体およびその製造法
US4782084A (en) * 1987-06-29 1988-11-01 Merck & Co., Inc. HMG-COA reductase inhibitors
US4997848A (en) * 1987-10-27 1991-03-05 Sankyo Company, Limited Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
CA2062023A1 (en) 1992-02-10 1993-08-11 Jagroop S. Dahiya Novel fungal strains and use thereof in antibiotic production
EP0629184A1 (en) * 1992-03-04 1994-12-21 Fujisawa Pharmaceutical Co., Ltd. TETRALIN DERIVATIVES AS HMG-CoA REDUCTASE INHIBITORS
NZ247617A (en) 1992-05-15 1995-07-26 Sankyo Co Octahydronaphthalene oxime derivatives and pharmaceutical compositions
US6812007B1 (en) * 1992-11-04 2004-11-02 Keri Vilmos Process for the isolation and purification of mevinolin
HU210867B (en) * 1992-11-04 1995-10-30 Biogal Gyogyszergyar Method for extraction and purification of mevinolin from culture medium
SI9300303A (en) * 1993-06-08 1994-12-31 Krka Tovarna Zdravil Process for isolation of hypolipemic effective substance
US5409820A (en) * 1993-08-06 1995-04-25 Apotex, Inc. Process for the production of lovastatin using Coniothyrium fuckelii
US7238348B2 (en) 1996-09-30 2007-07-03 Beijing Peking University Wbl Corporation Ltd. Method of treatment of osteoporosis with compositions of red rice fermentation products
US6046022A (en) 1996-09-30 2000-04-04 Peking University Methods and compositions employing red rice fermentation products
CZ300153B6 (cs) 1998-03-20 2009-02-25 Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság Metabolicky kontrolovaný proces fermentace pri výrobe lovastatinové hydroxykyseliny
JP3740062B2 (ja) 2000-02-24 2006-01-25 テバ ジョジセルジャール レースベニュタールシャシャーグ 培養液の精製方法
PL357533A1 (en) 2000-03-03 2004-07-26 Plus Chemicals, S.A. A process for purifying lovastatin and simvastatin with reduced levels of dimeric impurities
KR20010095780A (ko) * 2000-04-12 2001-11-07 나가오카 마사시 배아 홍국
IN192861B (es) 2000-06-30 2004-05-22 Ranbaxy Lab Ltd
AU2002235885A1 (en) 2001-02-09 2002-08-28 Unilever N.V. Process for the preparation of one or more statins by fermentation
KR100379075B1 (en) 2002-03-07 2003-04-08 Jinis Biopharmaceuticals Co Method for producing low cholesterol animal food product and food product therefrom
KR20020093147A (ko) * 2002-05-30 2002-12-13 지니스생명공학 주식회사 성인병 예방 및 치료 보조제
KR100710500B1 (ko) 2005-05-18 2007-04-24 고려대학교 산학협력단 홍국균을 이용한 모나콜린 k 생산방법
EP2327682A1 (en) 2009-10-29 2011-06-01 KRKA, D.D., Novo Mesto Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
WO2010069593A1 (en) 2008-12-19 2010-06-24 Krka, D. D., Novo Mesto Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
RO128803A0 (ro) 2012-10-12 2013-09-30 Ion Gigel Fulga Compoziţie pentru tratamentul sau prevenirea dislipidemiilor
CN110331151A (zh) * 2019-04-11 2019-10-15 北京工商大学 紫色红曲菌mokH基因过表达菌株的构建方法
CN111297938A (zh) * 2020-03-11 2020-06-19 北京康立生医药技术开发有限公司 一种辅助降血脂组合物中洛伐他汀的检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (es) 1974-06-07 1981-03-18
JPS55150898A (en) * 1979-05-11 1980-11-25 Sankyo Co Ltd Preparation of a new physiologically active substance mb-530b
GR69216B (es) * 1979-06-15 1982-05-07 Merck & Co Inc

Also Published As

Publication number Publication date
FI66427C (fi) 1984-10-10
FR2449685A1 (fr) 1980-09-19
SG6784G (en) 1985-02-08
FI800506A (fi) 1980-08-21
AU532626B2 (en) 1983-10-06
DK149095C (da) 1986-06-16
SU1158048A3 (ru) 1985-05-23
DD154494A5 (de) 1982-03-24
JPS55111790A (en) 1980-08-28
HU182069B (en) 1983-12-28
SE8001339L (sv) 1980-08-21
DK73080A (da) 1980-08-21
DE3006216C2 (de) 1985-10-31
SE453301B (sv) 1988-01-25
ES8103171A1 (es) 1981-02-16
KR830002801B1 (ko) 1983-12-16
GB2046737B (en) 1983-01-12
PH15145A (en) 1982-08-24
PL222120A1 (es) 1980-10-20
NZ192919A (en) 1984-07-06
ZA80962B (en) 1981-03-25
GB2046737A (en) 1980-11-19
PL124304B1 (en) 1983-01-31
FI66427B (fi) 1984-06-29
IE800321L (en) 1980-08-20
ES488796A0 (es) 1981-02-16
DK21889A (da) 1989-01-18
IE49743B1 (en) 1985-12-11
IT8067262A0 (it) 1980-02-20
NL8001041A (nl) 1980-08-22
ATA92980A (de) 1983-07-15
SU969702A1 (ru) 1982-10-30
IT1175260B (it) 1987-07-01
AT373915B (de) 1984-03-12
FR2449685B1 (fr) 1985-06-28
NO153974C (no) 1986-06-25
NL191540B (nl) 1995-05-01
DK21889D0 (da) 1989-01-18
DK149095B (da) 1986-01-20
DE3051175C2 (es) 1989-12-21
AU5567380A (en) 1980-08-28
DE3006216A1 (de) 1980-09-04
BE881825A (fr) 1980-08-20
CA1129794A (en) 1982-08-17
KR830002030A (ko) 1983-05-21
NO153974B (no) 1986-03-17
NO800451L (no) 1980-08-21
NL191540C (nl) 1995-09-04
JPS5925599B2 (ja) 1984-06-19
CH645890A5 (de) 1984-10-31

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