MX375019B - Membrana de hidrogel para prevención de la adhesión. - Google Patents

Membrana de hidrogel para prevención de la adhesión.

Info

Publication number
MX375019B
MX375019B MX2015007410A MX2015007410A MX375019B MX 375019 B MX375019 B MX 375019B MX 2015007410 A MX2015007410 A MX 2015007410A MX 2015007410 A MX2015007410 A MX 2015007410A MX 375019 B MX375019 B MX 375019B
Authority
MX
Mexico
Prior art keywords
membrane
adhesion prevention
hydrogel membrane
bioresorption
hyaluronate
Prior art date
Application number
MX2015007410A
Other languages
English (en)
Other versions
MX2015007410A (es
Inventor
Christine E Schmidt
Sarah M Mayes
Scott A Zawko
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Publication of MX2015007410A publication Critical patent/MX2015007410A/es
Publication of MX375019B publication Critical patent/MX375019B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
    • C08J5/18—Manufacture of films or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
    • A61F2002/009—Special surfaces of prostheses, e.g. for improving ingrowth for hindering or preventing attachment of biological tissue
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/04—Alginic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2405/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2401/00 or C08J2403/00
    • C08J2405/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Manufacturing & Machinery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)

Abstract

Una membrana biocompatible comprendida de alginato e hialuronato. La membrana puede ser usada para evitar la cicatrización indeseable después dela cirugía. La adherencia del tejido y la velocidad de biorresorción de la membrana pueden ser modificadas a través de un estímulo externo que comprende un agente secuestrante y un modificador de la viscosidad.
MX2015007410A 2012-12-11 2013-12-11 Membrana de hidrogel para prevención de la adhesión. MX375019B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261735852P 2012-12-11 2012-12-11
US201361807629P 2013-04-02 2013-04-02
US201361814944P 2013-04-23 2013-04-23
PCT/US2013/074388 WO2014093489A2 (en) 2012-12-11 2013-12-11 Hydrogel membrane for adhesion prevention

Publications (2)

Publication Number Publication Date
MX2015007410A MX2015007410A (es) 2015-12-15
MX375019B true MX375019B (es) 2025-03-06

Family

ID=50935077

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015007410A MX375019B (es) 2012-12-11 2013-12-11 Membrana de hidrogel para prevención de la adhesión.

Country Status (9)

Country Link
US (4) US9662424B2 (es)
EP (3) EP3505197B1 (es)
JP (7) JP6242910B2 (es)
KR (1) KR101766679B1 (es)
CN (1) CN104981259B (es)
BR (2) BR112015013711B8 (es)
CA (1) CA2894658C (es)
MX (1) MX375019B (es)
WO (1) WO2014093489A2 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8668863B2 (en) 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
JP6242910B2 (ja) 2012-12-11 2017-12-06 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 癒着防止のためのハイドロゲル膜
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
EP3485921B1 (en) * 2016-07-13 2025-07-23 Mochida Pharmaceutical Co., Ltd. Adhesion-preventing composition
CN106784406B (zh) 2016-12-28 2018-09-25 深圳市华星光电技术有限公司 一种oled器件的制备方法
WO2018164358A1 (ko) * 2017-03-07 2018-09-13 (주)진우바이오 히알루론산염 필름의 제조방법 및 이로부터 제조된 히알루론산염 필름
WO2018165327A1 (en) 2017-03-08 2018-09-13 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
JP6939607B2 (ja) * 2017-03-27 2021-09-22 Jsr株式会社 組成物およびその用途
CN109125814B (zh) * 2017-06-15 2021-11-09 上海微创医疗器械（集团）有限公司 防粘连膜及其制备方法
CN107823699B (zh) * 2017-11-17 2021-03-30 陕西慧康生物科技有限责任公司 止血防粘连膜及其制备方法
EP3741400B1 (en) * 2018-01-15 2026-03-11 Mochida Pharmaceutical Co., Ltd. Anti-adhesion composition
JP7071641B2 (ja) * 2018-10-18 2022-05-19 日本電信電話株式会社 積層体、積層体の製造方法および形状制御デバイス
US12576190B2 (en) 2019-08-15 2026-03-17 Axogen Corporation Tissue repair membrane adapted for adhesion and lubrication, and methods for preparing the same
EP4091813A4 (en) 2020-01-16 2023-03-29 FUJIFILM Corporation BIOLOGICAL MUCOSA MODEL, AND METHOD FOR EVALUATING RETENTION PROPERTIES OF MUCOSA PROTECTIVE AGENT
US20230293782A1 (en) * 2020-07-31 2023-09-21 Mochida Pharmaceutical Co., Ltd. Composition for preventing adhesion
EP3957311A1 (en) * 2020-08-20 2022-02-23 Assistance Publique, Hopitaux De Paris Alginate hydrogel and new composition derived therefrom for the treatment of ectopic calcifications
CN112826987A (zh) * 2021-01-27 2021-05-25 青岛琛蓝海洋生物工程有限公司 一种防粘连凝胶及其制备方法
WO2022172790A1 (ja) * 2021-02-10 2022-08-18 株式会社 資生堂 化粧料
CN113144048A (zh) * 2021-04-30 2021-07-23 佳木斯大学 一种治疗痛风性关节肿痛的中药外用贴剂及其制备方法
BE1029964B1 (fr) 2021-11-26 2023-06-27 Michel Heymans Kit à utiliser dans le traitement des cicatrices humaines
WO2025043025A2 (en) * 2023-08-21 2025-02-27 Board Of Regents, The University Of Texas System Methods for the synthesis of nanosheet membranes

Family Cites Families (204)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
US4196070A (en) 1977-12-12 1980-04-01 Nuclepore Corporation Method for forming microporous fluorocarbon polymer sheet and product
US4818542A (en) 1983-11-14 1989-04-04 The University Of Kentucky Research Foundation Porous microspheres for drug delivery and methods for making same
US6030958A (en) 1987-09-18 2000-02-29 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US4937270A (en) 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US5017229A (en) 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US6174999B1 (en) 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6610669B1 (en) 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
IT1248666B (it) 1990-05-30 1995-01-26 Fidia Spa Gel in forma di film autosupportanti altamente idrati, processo per laloro preparazione e impiego nella terapia di lesioni e/o patologie cutanee
US5204331A (en) * 1990-06-29 1993-04-20 Santen Pharmaceutical Co., Ltd. Composition for debridement of retained lens materials
GR920100122A (el) 1991-04-05 1993-03-16 Ethicon Inc Πολυσακχαρίτες οι οποίοι περιέχουν καρβοξύλιο με σταυροειδείς δεσμούς δια την πρόληψιν της προσφύσεως.
US5605938A (en) 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
JP2628229B2 (ja) 1991-10-15 1997-07-09 エフ エム シー コーポレーション β−１，３−グルカン多糖類、それを含む組成物、およびその製造と使用
IL103442A (en) 1991-10-18 1998-01-04 Ethicon Inc Installs the adhesive buffer
IT1254170B (it) 1991-12-18 1995-09-11 Mini Ricerca Scient Tecnolog Membrane composite per la rigenerazione guidata di tessuti
US7060287B1 (en) 1992-02-11 2006-06-13 Bioform Inc. Tissue augmentation material and method
US7968110B2 (en) 1992-02-11 2011-06-28 Merz Aesthetics, Inc. Tissue augmentation material and method
US5312333A (en) 1992-04-03 1994-05-17 United States Surgical Corporation Endoscopic material delivery device
US20040138329A1 (en) 1992-04-20 2004-07-15 Board Of Regents Of The University Of Texas System Gels for encapsulation of biological materials
US5266326A (en) 1992-06-30 1993-11-30 Pfizer Hospital Products Group, Inc. In situ modification of alginate
JPH06100468A (ja) 1992-09-25 1994-04-12 Kibun Food Chemifa Co Ltd 徐放性組成物
US5292525A (en) * 1992-10-14 1994-03-08 Merck & Co., Inc. Method and composition for removing an alginate from a cutaneous substrate
CA2114290C (en) 1993-01-27 2006-01-10 Nagabushanam Totakura Post-surgical anti-adhesion device
US5531716A (en) 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
ATE277640T1 (de) 1994-03-07 2004-10-15 Dow Chemical Co Bioaktive und/oder gezielte dendrimere-konjugate enthaltend genetisches material
US5981825A (en) 1994-05-13 1999-11-09 Thm Biomedical, Inc. Device and methods for in vivo culturing of diverse tissue cells
GB9413931D0 (en) 1994-07-11 1994-08-31 C V Lab Ltd Alginate fabric, method of preparation and use
GB9414304D0 (en) 1994-07-15 1994-09-07 C V Lab Ltd Fibres, manufacture and use
US5834029A (en) 1994-07-20 1998-11-10 Cytotherapeutics, Inc. Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment
US5531735A (en) 1994-09-27 1996-07-02 Hercules Incorporated Medical devices containing triggerable disintegration agents
US6294202B1 (en) 1994-10-06 2001-09-25 Genzyme Corporation Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers
US5563186A (en) 1994-11-21 1996-10-08 Thompson; Ronald G. Crosslinked alginate-based gels for matrix conformance
US20020131933A1 (en) 1996-01-16 2002-09-19 Yves Delmotte Biopolymer membrane and methods for its preparation
US5750585A (en) 1995-04-04 1998-05-12 Purdue Research Foundation Super absorbent hydrogel foams
US6150581A (en) 1995-06-07 2000-11-21 United States Surgical Corporation Chitosan/alginate anti-adhesion barrier
CA2224253A1 (en) 1995-06-09 1996-12-27 Martin J. Macphee Chitin hydrogels, methods of their production and use
EP0844891A4 (en) 1995-08-11 2004-05-06 Dow Chemical Co HYPER COMBED POLYMER CONJUGATES
BR9610996A (pt) 1995-08-29 1999-07-13 Fidia Advanced Biopolymers Srl Biomateriais para prevenção de ades es pós-cirúrgicas compreendendo derivados de ácidos hialurônico
US5855613A (en) 1995-10-13 1999-01-05 Islet Sheet Medical, Inc. Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change
US5684051A (en) 1996-04-24 1997-11-04 Hercules Incorporated Medical devices with improved elastic response
IL118376A0 (en) 1996-05-22 1996-09-12 Univ Ben Gurion Polysaccharide sponges for cell culture and transplantation
EP0907721A1 (en) 1996-05-28 1999-04-14 Brown University Research Foundation Hyaluronan based biodegradable scaffolds for tissue repair
US6500777B1 (en) 1996-06-28 2002-12-31 Ethicon, Inc. Bioresorbable oxidized cellulose composite material for prevention of postsurgical adhesions
US6060534A (en) 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
US6368356B1 (en) 1996-07-11 2002-04-09 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
US5866554A (en) 1996-07-19 1999-02-02 Shalaby; Shalaby W. Compositions for prevention of inflammation and adhesion formation and uses thereof
ES2317657T3 (es) 1996-09-19 2009-04-16 The Regents Of The University Of Michigan Polimeros que contienen polisacaridos tales como alginatos o alginatos modificados.
EP1806367A3 (en) 1996-09-19 2007-11-28 The Regents Of The University Of Michigan Polymers containing polysaccharides such as alginates or modified alginates
US7009034B2 (en) 1996-09-23 2006-03-07 Incept, Llc Biocompatible crosslinked polymers
US5863551A (en) 1996-10-16 1999-01-26 Organogel Canada Ltee Implantable polymer hydrogel for therapeutic uses
FR2755613B1 (fr) 1996-11-13 1999-01-08 Precis Produit de pansement a matrice d'alginate de calcium et son procede de fabrication
US5993661A (en) 1997-04-14 1999-11-30 The Research Foundation Of State University Of New York Macroporous or microporous filtration membrane, method of preparation and use
US5984948A (en) 1997-04-14 1999-11-16 Hasson; Harrith M. Device for closing an opening in tissue and method of closing a tissue opening using the device
US6281341B1 (en) 1997-04-30 2001-08-28 Biomm, Inc. & University Of Miami Hetero-polysaccharide conjugate and methods of making and using the same
US6271278B1 (en) 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
US6869938B1 (en) 1997-06-17 2005-03-22 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
JP2001520274A (ja) 1997-10-17 2001-10-30 アドバンスト・メディカル・ソリューションズ・リミテッド 発泡材料
US6410044B1 (en) 1998-03-19 2002-06-25 Surmodics, Inc. Crosslinkable macromers
US6007833A (en) 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
ATE502670T1 (de) 1998-08-14 2011-04-15 Incept Llc Apparat für die in-situ-bildung von hydrogelen
US6514534B1 (en) 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
US7347850B2 (en) 1998-08-14 2008-03-25 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
US6841153B1 (en) 1998-10-02 2005-01-11 University Of Florida Prevention of adhesions
JP4267106B2 (ja) * 1998-10-15 2009-05-27 株式会社クラレ 癒着防止用材料
US6977231B1 (en) 1999-01-21 2005-12-20 Nipro Corporation Suturable adhesion-preventing membrane
IL144597A0 (en) 1999-02-03 2002-05-23 Powderject Res Ltd Hydrogel particle formulations
DE19909214A1 (de) 1999-03-03 2000-09-07 Basf Ag Wasserabsorbierende, schaumförmige, vernetzte Polymerisate mit verbesserter Verteilungswirkung, Verfahren zu ihrer Herstellung und ihre Verwendung
US6767928B1 (en) 1999-03-19 2004-07-27 The Regents Of The University Of Michigan Mineralization and biological modification of biomaterial surfaces
AU776009B2 (en) 1999-04-09 2004-08-26 Regents Of The University Of Michigan, The Preparing porous hydrogel products
CA2377544C (en) 1999-07-28 2008-09-23 United States Surgical Corporation Hyaluronic acid anti-adhesion barrier
US6566345B2 (en) 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
CA2394653A1 (en) 2000-01-05 2001-07-12 Novartis Ag Hydrogels
JP2001212224A (ja) 2000-02-04 2001-08-07 Toyobo Co Ltd 創傷被覆材
US6521223B1 (en) 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
US6638917B1 (en) 2000-02-25 2003-10-28 Scimed Life Systems, Inc. Reducing adhesion
US6629997B2 (en) 2000-03-27 2003-10-07 Kevin A. Mansmann Meniscus-type implant with hydrogel surface reinforced by three-dimensional mesh
US6497887B1 (en) 2000-04-13 2002-12-24 Color Access, Inc. Membrane delivery system
JP2001340375A (ja) * 2000-05-31 2001-12-11 Toyobo Co Ltd 創傷被覆材
US6991652B2 (en) 2000-06-13 2006-01-31 Burg Karen J L Tissue engineering composite
CA2416126C (en) 2000-07-28 2011-07-05 Anika Therapeutics, Inc. Bioabsorbable composites of derivatized hyaluronic acid
US6599526B2 (en) 2000-08-18 2003-07-29 The University Of North Texas Health Science Center At Fort Worth Pericardial anti-adhesion patch
GB0103330D0 (en) 2001-02-10 2001-03-28 Surgical Innovations Ltd Laparoscopic gel applicator
US6913765B2 (en) 2001-03-21 2005-07-05 Scimed Life Systems, Inc. Controlling resorption of bioresorbable medical implant material
US6608117B1 (en) 2001-05-11 2003-08-19 Nanosystems Research Inc. Methods for the preparation of cellular hydrogels
US7201917B2 (en) 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
JP3805654B2 (ja) 2001-08-29 2006-08-02 株式会社ネクスト 止血・癒着防止性のバイオポリマーの微細粒子
US7347988B2 (en) 2001-11-15 2008-03-25 University Of North Texas Synthesis, uses and compositions of crystal hydrogels
US7629388B2 (en) 2001-11-20 2009-12-08 William Marsh Rice University Synthesis and characterization of biodegradable cationic poly(propylene fumarate-co-ethylene glycol) copolymer hydrogels modified with agmatine for enhanced cell adhesion
JP3796165B2 (ja) * 2001-11-20 2006-07-12 株式会社クラレ 癒着防止材
TWI255224B (en) 2002-01-09 2006-05-21 Novartis Ag Polymeric articles having a lubricious coating and method for making the same
US20050107868A1 (en) 2002-03-28 2005-05-19 JAPAN as represented by President of NATIONAL & CARDIOVASCULAR CENTER Scaffold for tissue engineering, artificial blood vessel, cuff, and biological implant covering member
WO2003089506A1 (en) 2002-04-22 2003-10-30 Purdue Research Foundation Hydrogels having enhanced elasticity and mechanical strength properties
DE10223310A1 (de) 2002-05-24 2003-12-11 Biotronik Mess & Therapieg Verfahren zum Beschichten von Implantaten mit einer Polysaccharid-Lage
JP2004041586A (ja) * 2002-07-15 2004-02-12 Fujimori Kogyo Co Ltd 生体適合性材料およびその製造方法
US7572894B2 (en) 2002-11-01 2009-08-11 Trustees Of Tufts College Templated native silk smectic gels
WO2004044281A2 (en) 2002-11-12 2004-05-27 The Regents Of The University Of California Nano-porous fibers and protein membranes
US7083697B2 (en) 2002-12-30 2006-08-01 Boston Scientific Scimed, Inc. Porous spun polymeric structures and method of making same
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
US8097273B2 (en) 2003-04-10 2012-01-17 Teijin Limited Biodegradable film having honeycomb structure
WO2005000402A2 (en) 2003-05-15 2005-01-06 University Of Utah Research Foundation Anti-adhesion composites and methods os use thereof
SE0301592D0 (sv) 2003-05-28 2003-05-28 Amersham Biosciences Ab Electrophoretic support
WO2005017009A1 (en) 2003-08-15 2005-02-24 The Texas A & M University System Hydrolytically stable isoelectric hydrogel compositions
AU2004268013B2 (en) 2003-08-29 2011-05-12 Mayo Foundation For Medical Education And Research Hydrogel porogens for fabricating biodegradable scaffolds
AU2004269196B2 (en) 2003-09-03 2010-03-04 Shmuel Bukshpan Methods and apparatus for rapid crystallization of biomolecules
US7235295B2 (en) 2003-09-10 2007-06-26 Laurencin Cato T Polymeric nanofibers for tissue engineering and drug delivery
US20130211320A1 (en) 2003-10-07 2013-08-15 Nawar Alkhamesi System and method for delivering an anti-adhesive substance to a body cavity
DE502004003914D1 (de) 2003-12-19 2007-07-05 Basf Ag Quellbare hydrogelbildende polymere mit geringem feinstaubanteil
WO2005077013A2 (en) 2004-02-06 2005-08-25 Georgia Tech Research Corporation Surface directed cellular attachment
US8277831B2 (en) 2004-02-17 2012-10-02 Advanced Technologies And Regenerative Medicine, Llc. Drug-enhanced adhesion prevention
JP2007529280A (ja) 2004-03-17 2007-10-25 ジェンザイム・コーポレーション 癒着防止スプレー
BRPI0510042B8 (pt) 2004-04-20 2021-06-22 Genzyme Corp implante semelhante à malha cirúrgica
US8030070B2 (en) 2004-04-28 2011-10-04 Sanofi Pasteur Vaxdesign Corp. Artificial lymphoid tissue equivalent
US7855074B2 (en) 2004-04-28 2010-12-21 Vaxdesign Corp. Artificial immune system: methods for making and use
US7758654B2 (en) 2004-05-20 2010-07-20 Kensey Nash Corporation Anti-adhesion device
WO2005120701A1 (en) 2004-06-07 2005-12-22 Mcmaster University Stable composite material comprising supported porous gels
ITRM20040318A1 (it) 2004-06-28 2004-09-28 Univ Palermo Idrogeli di acido ialuronico e alfa, beta-poliaspartilidrazide e loro applicazioni in campo biomedico e farmaceutico.
EP1778144B1 (en) 2004-08-17 2011-01-19 Tyco Healthcare Group LP Anti-adhesion barrier
US8663625B2 (en) 2004-10-15 2014-03-04 Cornell Research Foundation Diffusively permeable monolithic biomaterial with embedded microfluidic channels
US7252832B1 (en) 2004-12-13 2007-08-07 Biomet Sports Medicine, Inc. Composite collagen material and method of forming same
US20060233852A1 (en) 2005-04-19 2006-10-19 Promethean Surgical Devices Prosthetic for tissue reinforcement
AU2006244714A1 (en) 2005-05-13 2006-11-16 Protista Biotechnology Ab Macroporous hydrogels, their preparation and their use
WO2007016622A2 (en) 2005-08-02 2007-02-08 Wright Medical Technolody, Inc. Gel composition for inhibiting cellular adhesion
KR100785378B1 (ko) 2005-09-05 2007-12-14 주식회사 바이오레인 다층구조의 유착방지제
US7989505B2 (en) 2005-09-23 2011-08-02 University Of North Texas Synthesis of columnar hydrogel colloidal crystals in water-organic solvent mixture
EP3028677A1 (en) 2005-12-14 2016-06-08 Anika Therapeutics Inc. Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid
CA2633954A1 (en) * 2005-12-14 2007-06-21 Anika Therapeutics, Inc. Meniscal implant of hyaluronic acid derivatives for treatment of meniscal defects
US20100273667A1 (en) 2006-02-10 2010-10-28 The Regents Of The University Of Michigan Cell culture well-plates having inverted colloidal crystal scaffolds
US9028872B2 (en) * 2006-03-01 2015-05-12 Fmc Corporation Gelled composite
US8110242B2 (en) 2006-03-24 2012-02-07 Zimmer, Inc. Methods of preparing hydrogel coatings
US20080069857A1 (en) 2006-04-12 2008-03-20 Yoon Yeo Compositions And Methods For Inhibiting Adhesions
FI119177B (fi) * 2006-05-05 2008-08-29 Bioretec Oy Bioabsorboituva, muotoutuva fiksaatiomateriaali ja -implantti
US7833284B2 (en) 2006-06-28 2010-11-16 The Cleveland Clinic Foundation Anti-adhesion membrane
CA2686927A1 (en) 2006-07-06 2008-01-06 Abbott Respiratory Llc Superporous hydrogels for heavy-duty applications
EP2081964A4 (en) * 2006-10-12 2012-07-11 Univ Johns Hopkins ALGINATE AND ALGINATLYASE COMPOSITIONS AND USE METHOD
WO2008076339A2 (en) 2006-12-15 2008-06-26 Drexel University Multilayer films
US20080182012A1 (en) 2007-01-31 2008-07-31 Motorola, Inc. Micro fuel cell having macroporous metal current collectors
JP5059787B2 (ja) 2007-02-06 2012-10-31 帝人株式会社 セルロース誘導体およびその製造方法
US7504286B2 (en) 2007-03-28 2009-03-17 Advanced Micro Devices, Inc. Semiconductor memory devices and methods for fabricating the same
AU2008256864A1 (en) 2007-05-23 2008-12-04 Allergan, Inc. Coated hyaluronic acid particles
WO2008157280A1 (en) * 2007-06-13 2008-12-24 Fmc Corporation Implantable degradable biopolymer fiber devices
US7998380B2 (en) 2007-07-13 2011-08-16 Wisconsin Alumni Research Foundation Method of fabricating a tissue engineering scaffold
US20090062233A1 (en) 2007-08-09 2009-03-05 Xin Ji Modified starch material of biocompatible hemostasis
US20120070473A1 (en) 2007-08-17 2012-03-22 Anhese Llc Apparatus and Method for Reducing the Occurrence of Post-Surgical Adhesions
US8075908B2 (en) 2007-08-17 2011-12-13 Anhese Llc Apparatus and method for reducing the occurrence of post-surgical adhesions
CN104874007A (zh) 2007-08-28 2015-09-02 奥塔哥创新有限公司 手术用水凝胶
US7919542B2 (en) 2007-11-12 2011-04-05 Zimmer Spine, Inc. Phase separated, branched, copolymer hydrogel
JP2011507665A (ja) 2007-12-31 2011-03-10 アクラレント インコーポレイテッド 粘膜組織包帯剤及び使用方法
EP2082755A1 (de) * 2008-01-16 2009-07-29 CellMed AG Monolithische in-situ vernetzte Alginatimplantate
US8668863B2 (en) * 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
US20090294049A1 (en) 2008-06-02 2009-12-03 Medtronic Vascular, Inc. Biodegradable Adhesive Hydrogels
US20100015231A1 (en) 2008-07-17 2010-01-21 E.I. Du Pont De Nemours And Company Low swell, long-lived hydrogel sealant
US8551136B2 (en) 2008-07-17 2013-10-08 Actamax Surgical Materials, Llc High swell, long-lived hydrogel sealant
US20100055158A1 (en) * 2008-08-28 2010-03-04 Tyco Healthcare Group Lp Environmentally Activated Compositions, Articles and Methods
US20110212501A1 (en) * 2008-09-12 2011-09-01 The Brigham And Women's Hospital, Inc. 3-dimensional multi-layered hydrogels and methods of making the same
FR2937857B1 (fr) 2008-10-30 2015-04-03 Brothier Lab Membrane chirurgicale antiadherence
US8927521B2 (en) 2008-11-10 2015-01-06 University of Pittsburgh—of the Commonwealth System of Higher Education Cyclic adenosine monophosphates for reducing the formation of adhesions
US9622481B2 (en) 2009-01-23 2017-04-18 Kane Biotech Inc. Biofilm-removing antimicrobial compositions and uses thereof
JP5724108B2 (ja) * 2009-04-22 2015-05-27 メドスキン ソリューションズ ドクター ズベラック アーゲーＭｅｄＳｋｉｎ Ｓｏｌｕｔｉｏｎｓ Ｄｒ．Ｓｕｗｅｌａｃｋ ＡＧ 凍結乾燥組成物
HRP20190940T1 (hr) 2009-06-15 2019-09-20 Cartiheal (2009) Ltd. Čvrsti oblici za popravak tkiva
US9592108B2 (en) 2009-07-29 2017-03-14 Covidien Lp System and method of laparoscopic use of hemostatic patch
BR112012009266A2 (pt) 2009-10-21 2016-05-31 Bayer Materialscience Ag hidrogel biodegradável
KR20090130277A (ko) 2009-11-29 2009-12-22 이정삼 단일공을 통한 복강경하 탈장수술에 이용되는 특수 인공막
JP5591995B2 (ja) 2010-03-30 2014-09-17 イストセル，エセ．エレ． ウォートンジェリー臍帯由来の新規の生体材料
BR112012025557A2 (pt) 2010-04-22 2016-06-28 Teijin Ltd hidrogel, e, método para fabricar um hidrogel
WO2012024339A1 (en) * 2010-08-16 2012-02-23 Mast Biosurgery Ag Anti-adhesion alginate barrier of variable absorbance
WO2012048283A1 (en) * 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
JP5999567B2 (ja) 2010-10-20 2016-09-28 ディーエスエム アイピー アセッツ ビー．ブイ． ペンダント型親水性物質を有する生分解性組成物および関連デバイス
CN103189078A (zh) 2010-10-29 2013-07-03 汇美迪斯有限公司 含有透明质酸和l-精氨酸的抗粘连剂
CN102475691B (zh) 2010-11-30 2014-04-16 中国科学院大连化学物理研究所 海藻酸盐-壳聚糖酰基衍生物微胶囊及其制备和应用
WO2012082581A2 (en) 2010-12-13 2012-06-21 Richard Massen Hernia mesh apparatus and method
US8597264B2 (en) 2011-03-24 2013-12-03 Kci Licensing, Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
US8404256B2 (en) 2011-05-06 2013-03-26 The University Of Memphis Research Foundation Biomaterial composite composition and method of use
WO2012165462A1 (ja) 2011-05-31 2012-12-06 国立大学法人 東京大学 ハイドロゲル及びその製造方法
TW201325618A (zh) 2011-08-30 2013-07-01 Mast Biosurgery Ag 可作為外科屏障之聚乳酸／褐藻酸鹽複合物
KR101507301B1 (ko) 2011-10-28 2015-04-01 주식회사 제닉 점착성 하이드로겔 조성물 및 이를 이용한 점착성 하이드로겔 시트의 제조방법
WO2013090145A1 (en) 2011-12-13 2013-06-20 Boston Scientific Scimed, Inc. Decalcifying heart valve
KR101330652B1 (ko) 2012-02-28 2013-11-18 (주)시지바이오 성장인자 담지 가능한 유착방지용 고분자 조성물
DE102012104530A1 (de) 2012-05-25 2013-11-28 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Verwendung einer biokompatiblen Zusammensetzung
US9421221B2 (en) 2012-11-12 2016-08-23 Warsaw Orthopedic, Inc. Compositions and methods for inhibiting adhesion formation
JP6242910B2 (ja) 2012-12-11 2017-12-06 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 癒着防止のためのハイドロゲル膜
KR102078334B1 (ko) 2013-02-28 2020-02-18 아이큐어 주식회사 시트리스 하이드로겔 필름 및 그 이의 제조 방법
US20150064143A1 (en) 2013-09-04 2015-03-05 Industry-University Cooperation Foundation Hanyang University Ionically cross-linkable alginate-grafted hyaluronate compound
WO2018056937A2 (en) 2016-07-29 2018-03-29 Karaca Esra Nanofibrous adhesion barrier
CN109715222A (zh) 2016-09-30 2019-05-03 东丽株式会社 防粘连材料
KR101985368B1 (ko) 2016-11-24 2019-09-03 비엘테크 주식회사 보습력이 우수한 하이드로겔 조성물 및 이를 이용한 시트
KR102142720B1 (ko) 2018-02-06 2020-08-07 (주)현우테크 점착성이 우수한 유착 방지 필름
CN108969392A (zh) 2018-08-22 2018-12-11 泉州三欣新材料科技有限公司 一种具有吸附重金属功能的组合物和应用
WO2020051920A1 (zh) 2018-09-15 2020-03-19 深圳先进技术研究院 一种可控双向三维形变水凝胶薄膜及其制备方法和柔性微电极阵列
CN109294002B (zh) 2018-09-15 2021-05-04 深圳先进技术研究院 一种可控双向三维形变水凝胶薄膜及其制备方法和柔性微电极阵列
US12403157B2 (en) 2019-03-05 2025-09-02 Medcura, Inc. System and method to reduce tissue ororgan adhesion
BR112022009955A2 (pt) 2019-12-13 2022-08-09 Massachusetts Inst Technology Barreiras de tecido sintético e seus usos
EP4114479A4 (en) 2020-03-02 2024-04-03 Sporogenics Pte. Ltd. ADHESIVE BARRIER COMPOSITION, METHOD OF PREPARING AND USE THEREOF
KR102409731B1 (ko) 2020-04-03 2022-06-15 한양대학교 산학협력단 이중 가교된 자가치유 하이드로젤
US20230293782A1 (en) 2020-07-31 2023-09-21 Mochida Pharmaceutical Co., Ltd. Composition for preventing adhesion
EP3957311A1 (en) 2020-08-20 2022-02-23 Assistance Publique, Hopitaux De Paris Alginate hydrogel and new composition derived therefrom for the treatment of ectopic calcifications
KR102388506B1 (ko) 2021-06-14 2022-04-20 (주)씨앤엘디 유착방지용 조성물
KR102388509B1 (ko) 2021-06-14 2022-04-20 (주)씨앤엘디 점막 부착성과 팽윤성이 우수한 필름 형태의 유착방지용 조성물
WO2023019143A1 (en) 2021-08-09 2023-02-16 Gel4Med, Inc. Films formed from self-assembling peptide hydrogels
CN113813448B (zh) 2021-10-08 2022-12-06 大连大学附属中山医院 一种含有类软骨陷窝结构的硬度可调水凝胶支架
CN114984300B (zh) 2022-05-30 2023-08-01 浙江大学 一种强韧抗菌水凝胶敷料及其制备方法
CN116019973B (zh) 2023-01-18 2025-03-07 东南大学 基于纳米酶复合体的纳米杂化双网络水凝胶及其制备方法与应用

Also Published As

Publication number Publication date
US9662424B2 (en) 2017-05-30
JP6686195B2 (ja) 2020-04-22
BR112015013711B8 (pt) 2019-10-22
US20150320915A1 (en) 2015-11-12
KR101766679B1 (ko) 2017-08-09
US10850011B2 (en) 2020-12-01
EP3505197B1 (en) 2023-09-06
JP2019081004A (ja) 2019-05-30
EP2931327A2 (en) 2015-10-21
US20170252491A1 (en) 2017-09-07
EP2931327B1 (en) 2019-02-13
CN104981259B (zh) 2017-03-08
AU2013359344A1 (en) 2015-07-23
CN104981259A (zh) 2015-10-14
BR112015013774A2 (pt) 2017-07-11
EP2931327A4 (en) 2016-08-03
US10272184B2 (en) 2019-04-30
WO2014093489A2 (en) 2014-06-19
JP7263459B2 (ja) 2023-04-24
JP6946506B2 (ja) 2021-10-06
JP7615201B2 (ja) 2025-01-16
CA2894658A1 (en) 2014-06-19
MX2015007410A (es) 2015-12-15
BR112015013711B1 (pt) 2019-08-27
JP2022001268A (ja) 2022-01-06
JP6538139B2 (ja) 2019-07-03
US20190216987A1 (en) 2019-07-18
KR20150095775A (ko) 2015-08-21
EP4253454A2 (en) 2023-10-04
JP2016502874A (ja) 2016-02-01
JP6242910B2 (ja) 2017-12-06
JP2023090744A (ja) 2023-06-29
JP2018020213A (ja) 2018-02-08
JP2020114442A (ja) 2020-07-30
WO2014093489A3 (en) 2014-10-16
US12453804B2 (en) 2025-10-28
US20230173144A1 (en) 2023-06-08
CA2894658C (en) 2017-07-04
EP4253454A3 (en) 2024-01-03
JP2025060921A (ja) 2025-04-10
EP3505197A1 (en) 2019-07-03

Similar Documents

Publication Publication Date Title
MX2015007410A (es) Membrana de hidrogel para prevencion de la adhesion.
WO2013106385A3 (en) System and methods for determining tissue elasticity
EP2777726A3 (en) Medical devices
BR112012009287A2 (pt) dispositivo de embolização feito de polímero expansível
BR112013021127B8 (pt) Dispositivo de implante afastador de válvula nasal bioabsorvível
BR112015022161A2 (pt) implante intraocular contendo prostamida
GB201101429D0 (en) Drug delivery system
PT2173324T (pt) Gel injetável de ácido hialurónico para tratamento de degenerescências articulares
MX360833B (es) Formulacion acuosa esteril inyectable basada en acido hialuronico reticulado e hidroxiapatita para uso para estético.
BR112013024968A2 (pt) composição farmacêutica, e, método de tratamento de uma convulsão
SG10201806020VA (en) Electroactive bioadhesive compositions
BR112014029349A2 (pt) métodos, sistemas e dispositivos para administração de fármacos e oclusão vascular
FR3008885B1 (fr) Dispositif chirurgical notamment pour la pose de prothese de cordage mitrale
EP3067074A4 (en) Biomaterial having enhanced rubber properties through natural cross-linkage of collagen and hyaluronic acid, preparing method thereof, and using method thereof
EP3291747A4 (en) BIOKOMPATIBLE BIOMEDICAL OCCLUSION DEVICE
TN2015000520A1 (en) Pharmaceutical compositions comprising collagen and sodium hyaluronate
BR112014024448A2 (pt) composição, e, métodos para reduzir a viscosidade de um gel de polissacarídeo e para tratamento de uma formação subterrânea
MX2015011283A (es) Composicion inyectable de colageno polimerizable in situ.
MX2016014050A (es) Combinacion de un acido hialuronico y un polisacarido sulfatado.
EP2818172A4 (en) TLR4 MEDIUM, TISSUE HOMEOSTAT, HEPATOCYTE GROWTH FACTOR INDUCTOR, TISSUE-DISAPPEARING AGENT, AND SIRTUINE INDUCTOR WITH HYALURONIC ACID FRAGMENTS AS ACTIVE AGENTS THEREOF
WO2018213842A3 (en) Elestomeric fibrous hybrid scaffold for in vitro and in vivo formation
EP3706664A4 (en) EYE SURGICAL INJECTOR SYSTEM
MY175743A (en) Combination treatment comprising sulphated glycosaminoglycans for inducing labor
PL2288744T3 (pl) Połączenie błony i hydrożelu na bazie chitozanu i jego zastosowania w chirurgii
BR112012029747A2 (pt) composição de tratamento da pele, método para fornecer um efeito antimicrobiano para a pele e utilização de uma composição

Legal Events

Date Code Title Description
FG Grant or registration