MX370217B - Composicion inyectable de colageno polimerizable in situ. - Google Patents
Composicion inyectable de colageno polimerizable in situ.Info
- Publication number
- MX370217B MX370217B MX2015011283A MX2015011283A MX370217B MX 370217 B MX370217 B MX 370217B MX 2015011283 A MX2015011283 A MX 2015011283A MX 2015011283 A MX2015011283 A MX 2015011283A MX 370217 B MX370217 B MX 370217B
- Authority
- MX
- Mexico
- Prior art keywords
- injectable
- collagen composition
- acid soluble
- soluble collagen
- situ polymerizable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/505—Stabilizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/95—Involves in-situ formation or cross-linking of polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
Abstract
La presente invención se refiere a una composición inyectable de colágeno soluble en ácido, caracterizada porque comprende, una solución neutralizada que comprende el colágeno soluble en ácido, EDTA y un poliol, en donde dicha composición es inyectable a un pH neutralizado, y en donde dicho colágeno soluble en ácido sufre fibrillogénesis tras la exposición a fluidos con contenido iónico para formar una matriz de fibrillas de colágeno opaco.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361851119P | 2013-03-04 | 2013-03-04 | |
PCT/US2014/020217 WO2014138021A1 (en) | 2013-03-04 | 2014-03-04 | Injectable in situ polymerizable collagen composition |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015011283A MX2015011283A (es) | 2016-04-04 |
MX370217B true MX370217B (es) | 2019-12-05 |
Family
ID=51491854
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015011283A MX370217B (es) | 2013-03-04 | 2014-03-04 | Composicion inyectable de colageno polimerizable in situ. |
Country Status (13)
Country | Link |
---|---|
US (2) | US10111981B2 (es) |
EP (1) | EP2964184B1 (es) |
JP (1) | JP6382854B2 (es) |
KR (1) | KR20150126647A (es) |
CN (1) | CN105209005B (es) |
AU (1) | AU2014226064B2 (es) |
BR (1) | BR112015021146B1 (es) |
CA (1) | CA2901753C (es) |
EA (1) | EA201591621A1 (es) |
ES (1) | ES2678875T3 (es) |
IL (1) | IL240566B (es) |
MX (1) | MX370217B (es) |
WO (1) | WO2014138021A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2019448466A1 (en) * | 2019-05-27 | 2021-12-23 | Datum Dental Ltd. | Collagen compositions and uses thereof |
US20230119502A1 (en) * | 2020-03-30 | 2023-04-20 | Northeastern University | Collagen Nucleation Inhibitors |
CN111374940A (zh) * | 2020-04-13 | 2020-07-07 | 宁波赛缪斯生物科技有限公司 | 一种可原位聚合的胶原注射剂及其使用方法 |
WO2022237900A1 (en) * | 2021-05-13 | 2022-11-17 | Shanghai Qisheng Biological Preparation Co., Ltd. | Derivatized or rapidly polymerizing collagen compositions for tissue augmentation containing non-resorbable or slowly resorbable polymers |
WO2023030435A1 (en) * | 2021-09-01 | 2023-03-09 | Shanghai Qisheng Biological Preparation Co., Ltd. | Cartilage regeneration using injectable, in situ polymerizable collagen compositions containing chondrocytes or stem cells |
Family Cites Families (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3949073A (en) * | 1974-11-18 | 1976-04-06 | The Board Of Trustees Of Leland Stanford Junior University | Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution |
US4488911A (en) | 1975-10-22 | 1984-12-18 | Luck Edward E | Non-antigenic collagen and articles of manufacture |
US4424208A (en) * | 1982-01-11 | 1984-01-03 | Collagen Corporation | Collagen implant material and method for augmenting soft tissue |
US4582640A (en) | 1982-03-08 | 1986-04-15 | Collagen Corporation | Injectable cross-linked collagen implant material |
JPS6028936A (ja) * | 1983-07-27 | 1985-02-14 | Koken:Kk | アテロコラ−ゲン水溶液およびその製造方法 |
US5037377A (en) * | 1984-11-28 | 1991-08-06 | Medtronic, Inc. | Means for improving biocompatibility of implants, particularly of vascular grafts |
US4642117A (en) | 1985-03-22 | 1987-02-10 | Collagen Corporation | Mechanically sheared collagen implant material and method |
US4992226A (en) | 1985-03-28 | 1991-02-12 | Collagen Corporation | Method of making molds with xenogeneic collagen/mineral preparations for bone repair |
US5436135A (en) | 1985-09-02 | 1995-07-25 | Pasteur Merieux Serums Et Vaccins | New preparation of placenta collagen, their extraction method and their applications |
US4803075A (en) | 1986-06-25 | 1989-02-07 | Collagen Corporation | Injectable implant composition having improved intrudability |
US4969912A (en) * | 1988-02-18 | 1990-11-13 | Kelman Charles D | Human collagen processing and autoimplant use |
US5162430A (en) | 1988-11-21 | 1992-11-10 | Collagen Corporation | Collagen-polymer conjugates |
US5510418A (en) | 1988-11-21 | 1996-04-23 | Collagen Corporation | Glycosaminoglycan-synthetic polymer conjugates |
US5475052A (en) | 1988-11-21 | 1995-12-12 | Collagen Corporation | Collagen-synthetic polymer matrices prepared using a multiple step reaction |
US5306500A (en) | 1988-11-21 | 1994-04-26 | Collagen Corporation | Method of augmenting tissue with collagen-polymer conjugates |
US5800541A (en) | 1988-11-21 | 1998-09-01 | Collagen Corporation | Collagen-synthetic polymer matrices prepared using a multiple step reaction |
WO1993002639A1 (en) | 1991-08-06 | 1993-02-18 | Autogenesis Technologies, Inc. | Injectable collagen-based compositions for making intraocular lens |
AU3665693A (en) | 1992-02-28 | 1993-09-13 | Collagen Corporation | High concentration homogenized collagen compositions |
US5492135A (en) * | 1992-09-09 | 1996-02-20 | Devore; Dale P. | Collagen modulators for use in photoablation excimer laser keratectomy |
CA2140053C (en) | 1994-02-09 | 2000-04-04 | Joel S. Rosenblatt | Collagen-based injectable drug delivery system and its use |
CA2146090C (en) | 1994-05-10 | 1998-11-24 | Mark E. Mitchell | Apparatus and method of mixing materials in a sterile environment |
US5699810A (en) * | 1994-11-10 | 1997-12-23 | Pallikaris; Ioannis G. | Procedure for removal of soft eye tissue |
US5900245A (en) | 1996-03-22 | 1999-05-04 | Focal, Inc. | Compliant tissue sealants |
US6833408B2 (en) | 1995-12-18 | 2004-12-21 | Cohesion Technologies, Inc. | Methods for tissue repair using adhesive materials |
EP1704878B1 (en) | 1995-12-18 | 2013-04-10 | AngioDevice International GmbH | Crosslinked polymer compositions and methods for their use |
AU6662698A (en) | 1997-02-20 | 1998-09-09 | Gregory S. Keller | Augmentation and repair of dermal, subcutaneous, and vocal cord tissue defects |
WO1998057678A2 (en) | 1997-06-18 | 1998-12-23 | Cohesion Technologies, Inc. | Compositions containing thrombin and microfibrillar collagen |
EP1059943B1 (en) | 1998-03-06 | 2004-12-01 | Biosepra Medical Inc. | Implantable particles for tissue bulking and the treatment of gastroesophageal reflux disease, urinary incontinence, and skin wrinkles |
BR0008787A (pt) | 1999-02-12 | 2001-11-06 | Collagenesis Inc | Sistema à base de colágeno injetável para aplicação de células ou agentes terapêuticos |
WO2000047114A1 (en) | 1999-02-12 | 2000-08-17 | Collagenesis, Inc. | Injectable collagen-based delivery system for bone morphogenic proteins |
US6312725B1 (en) | 1999-04-16 | 2001-11-06 | Cohesion Technologies, Inc. | Rapid gelling biocompatible polymer composition |
US6592794B1 (en) | 1999-09-28 | 2003-07-15 | Organogenesis Inc. | Process of making bioengineered collagen fibrils |
AU1658601A (en) | 1999-11-15 | 2001-05-30 | The Texas A & M University System | Wound sealant formed in situ |
US6682760B2 (en) | 2000-04-18 | 2004-01-27 | Colbar R&D Ltd. | Cross-linked collagen matrices and methods for their preparation |
AU2002220396A1 (en) * | 2000-11-15 | 2002-05-27 | Bio Syntech Canada Inc | Filler composition for soft tissue augmentation and reconstructive surgery |
US20030181371A1 (en) | 2001-12-28 | 2003-09-25 | Angiotech Pharmaceuticals, Inc. | Compositions and methods of using collajolie |
WO2004047622A2 (en) | 2002-11-26 | 2004-06-10 | Crosscart, Inc. | Substantially non-immunogenic injectable collagen |
CN1310946C (zh) * | 2002-12-18 | 2007-04-18 | 和康生物科技股份有限公司 | 注射性胶原蛋白的制备方法及其产品 |
EP1594558A1 (en) | 2003-01-31 | 2005-11-16 | Zimmer Orthobiologics, Inc. | Hydrogel compositions comprising nucleus pulposus tissue |
WO2004073759A1 (en) | 2003-02-19 | 2004-09-02 | Aventis Pharmaceuticals Holdings Inc. | Composition and method for intradermal soft tissue augmentation |
IL155866A0 (en) | 2003-05-12 | 2003-12-23 | Yissum Res Dev Co | Responsive polymeric system |
US20050208095A1 (en) | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
CN101080246A (zh) | 2004-04-28 | 2007-11-28 | 安希奥设备国际有限责任公司 | 用于形成交联生物材料的组合物和系统及关联的制备方法与用途 |
EP1773417A1 (en) | 2004-06-23 | 2007-04-18 | Angiotech Pharmaceuticals (US), Inc. | Methods and crosslinked polymer compositions for cartilage repair |
US7597687B2 (en) | 2004-10-29 | 2009-10-06 | Spinal Restoration, Inc. | Injection of fibrin sealant including an anesthetic in spinal applications |
US7244270B2 (en) | 2004-09-16 | 2007-07-17 | Evera Medical | Systems and devices for soft tissue augmentation |
US20060100138A1 (en) | 2004-11-10 | 2006-05-11 | Olsen David R | Implantable collagen compositions |
WO2006086607A2 (en) * | 2005-02-10 | 2006-08-17 | Emory University | Novel proteins with enhanced functionality and methods of making novel proteins using circular permutation |
CA2610928A1 (en) * | 2005-06-10 | 2006-12-21 | Celgene Corporation | Human placental collagen compositions, processes for their preparation, methods of their use and kits comprising the compositions |
EP1926504B1 (en) | 2005-09-21 | 2010-01-13 | SurModics, Inc. | In situ occluding compositions ncluding natural biodegradable polysaccharides |
EP1996243B1 (en) | 2006-01-11 | 2014-04-23 | HyperBranch Medical Technology, Inc. | Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices |
ATE522231T1 (de) * | 2006-06-30 | 2011-09-15 | Univ Kyoto | Dünnfilm-multilokular-struktur mit kollagen, diese enthaltendes material zur geweberegeneration und herstellungsverfahren dafür |
WO2008036393A1 (en) | 2006-09-21 | 2008-03-27 | Purdue Research Foundation | Collagen preparation and method of isolation |
EP2184995A4 (en) | 2007-08-03 | 2012-02-29 | Univ Massachusetts Medical | COMPOSITE MATERIALS FOR BIOMEDICAL APPLICATIONS |
EP2033689A1 (en) | 2007-08-22 | 2009-03-11 | Italfarmacia S.r.l. | Injectable dermatological composition for treatment of the wrinkles |
CA2707649A1 (en) | 2007-11-02 | 2009-05-07 | Genzyme Corporation | Methods of augmenting or repairing soft tissue |
EP2229147A2 (en) | 2007-12-03 | 2010-09-22 | The Johns Hopkins University | Methods of synthesis and use of chemospheres |
JP5739668B2 (ja) | 2008-02-13 | 2015-06-24 | ハイパーブランチ メディカル テクノロジー, インコーポレイテッド | 調節可能な分解速度を有する架橋ポリアルキレンイミンヒドロゲル |
US9393267B2 (en) | 2009-02-19 | 2016-07-19 | University Of Southern California | Gel delivery system for tissue repair |
US7964704B2 (en) | 2009-07-27 | 2011-06-21 | Life Fusion, Llc | Preparation of high purity collagen |
EP2499167A4 (en) | 2009-11-09 | 2013-07-10 | Univ Drexel | COMPOSITIONS AND METHODS FOR TREATING AN ILLNESS OR MALFUNCTION IN SOFT TISSUE |
CA2807376A1 (en) | 2010-08-02 | 2012-02-09 | Euclid Systems Corporation | Collagen-based implants for sustained delivery of drugs |
WO2012167249A2 (en) * | 2011-06-02 | 2012-12-06 | Indiana University Research And Technology Corporation | Materials and methods for controlling vasculogenesis from endothelial colony forming cells |
US9782457B2 (en) * | 2011-10-07 | 2017-10-10 | Tissue Repair Company | Flowable formulations for tissue repair and regeneration |
-
2014
- 2014-03-04 KR KR1020157027248A patent/KR20150126647A/ko not_active Application Discontinuation
- 2014-03-04 BR BR112015021146-1A patent/BR112015021146B1/pt active IP Right Grant
- 2014-03-04 JP JP2015561530A patent/JP6382854B2/ja active Active
- 2014-03-04 AU AU2014226064A patent/AU2014226064B2/en not_active Expired - Fee Related
- 2014-03-04 US US14/430,741 patent/US10111981B2/en active Active
- 2014-03-04 ES ES14759906.2T patent/ES2678875T3/es active Active
- 2014-03-04 CN CN201480025240.5A patent/CN105209005B/zh active Active
- 2014-03-04 CA CA2901753A patent/CA2901753C/en active Active
- 2014-03-04 EA EA201591621A patent/EA201591621A1/ru unknown
- 2014-03-04 WO PCT/US2014/020217 patent/WO2014138021A1/en active Application Filing
- 2014-03-04 MX MX2015011283A patent/MX370217B/es active IP Right Grant
- 2014-03-04 EP EP14759906.2A patent/EP2964184B1/en active Active
-
2015
- 2015-08-13 IL IL240566A patent/IL240566B/en active IP Right Grant
-
2018
- 2018-10-18 US US16/164,052 patent/US11235089B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2014226064A1 (en) | 2015-10-15 |
IL240566A0 (en) | 2015-09-24 |
BR112015021146A2 (pt) | 2020-03-10 |
WO2014138021A1 (en) | 2014-09-12 |
US10111981B2 (en) | 2018-10-30 |
US20190046686A1 (en) | 2019-02-14 |
MX2015011283A (es) | 2016-04-04 |
AU2014226064B2 (en) | 2018-11-01 |
US20150367029A1 (en) | 2015-12-24 |
CA2901753C (en) | 2023-08-22 |
IL240566B (en) | 2020-05-31 |
ES2678875T3 (es) | 2018-08-20 |
JP2016510610A (ja) | 2016-04-11 |
JP6382854B2 (ja) | 2018-08-29 |
EP2964184A4 (en) | 2016-12-07 |
CN105209005A (zh) | 2015-12-30 |
CA2901753A1 (en) | 2014-09-12 |
EA201591621A1 (ru) | 2015-12-30 |
BR112015021146B1 (pt) | 2020-06-30 |
EP2964184A1 (en) | 2016-01-13 |
KR20150126647A (ko) | 2015-11-12 |
US11235089B2 (en) | 2022-02-01 |
EP2964184B1 (en) | 2018-05-09 |
CN105209005B (zh) | 2019-03-12 |
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