MX363403B - Inmumoensayo con interferencia suprimida para la deteccion de anticuerpos anti-farmacos en muestras de suero. - Google Patents
Inmumoensayo con interferencia suprimida para la deteccion de anticuerpos anti-farmacos en muestras de suero.Info
- Publication number
- MX363403B MX363403B MX2015016389A MX2015016389A MX363403B MX 363403 B MX363403 B MX 363403B MX 2015016389 A MX2015016389 A MX 2015016389A MX 2015016389 A MX2015016389 A MX 2015016389A MX 363403 B MX363403 B MX 363403B
- Authority
- MX
- Mexico
- Prior art keywords
- drug antibody
- tracer
- capture
- immunoassay
- suppressed
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Oncology (AREA)
- Mycology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13175091 | 2013-07-04 | ||
| PCT/EP2014/063891 WO2015000865A1 (en) | 2013-07-04 | 2014-07-01 | Interference-suppressed immunoassay to detect anti-drug antibodies in serum samples |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015016389A MX2015016389A (es) | 2016-04-11 |
| MX363403B true MX363403B (es) | 2019-03-22 |
Family
ID=48703341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015016389A MX363403B (es) | 2013-07-04 | 2014-07-01 | Inmumoensayo con interferencia suprimida para la deteccion de anticuerpos anti-farmacos en muestras de suero. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10168326B2 (enExample) |
| EP (1) | EP3017303B1 (enExample) |
| JP (2) | JP6563910B2 (enExample) |
| KR (1) | KR102248581B1 (enExample) |
| CN (1) | CN105378480B (enExample) |
| BR (1) | BR112015032960B1 (enExample) |
| CA (1) | CA2913687C (enExample) |
| MX (1) | MX363403B (enExample) |
| RU (1) | RU2674996C2 (enExample) |
| WO (1) | WO2015000865A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2401040A (en) | 2003-04-28 | 2004-11-03 | Chugai Pharmaceutical Co Ltd | Method for treating interleukin-6 related diseases |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| US20110117087A1 (en) | 2009-10-26 | 2011-05-19 | Reinhard Franze | Method for the production of a glycosylated immunoglobulin |
| KR101933197B1 (ko) | 2010-11-08 | 2018-12-27 | 제넨테크, 인크. | 피하 투여용 항―ｉｌ―6 수용체 항체 |
| EP4137816B1 (en) * | 2014-02-11 | 2025-03-19 | Genzyme Corporation | Assays for detecting the presence or amount of an anti-drug antibody |
| WO2017102786A1 (en) * | 2015-12-16 | 2017-06-22 | F. Hoffmann-La Roche Ag | Three-step acid dissociation enzyme linked immunosorbent (tadelis) assay |
| JP7376361B2 (ja) * | 2017-03-07 | 2023-11-08 | エフ． ホフマン－ラ ロシュ アーゲー | 免疫調節マクロライドのための安定な配合物 |
| CN110997727B (zh) * | 2017-08-08 | 2025-03-18 | 豪夫迈·罗氏有限公司 | 用于确定微型猪样品中抗药物抗体的方法 |
| JP7161534B2 (ja) * | 2017-11-29 | 2022-10-26 | エフ．ホフマン－ラ ロシュ アーゲー | 標的による干渉が抑制された抗薬物抗体アッセイ |
| BR112020022912A2 (pt) | 2018-07-10 | 2021-02-23 | Regeneron Pharmaceuticals, Inc. | métodos para mitigar a interferência de alvo de fármaco em um imunoensaio de anticorpo antifármaco (ada) |
| EP3969907B1 (en) * | 2019-05-13 | 2025-09-24 | F. Hoffmann-La Roche AG | Interference-suppressed pharmacokinetic immunoassay |
| EP4085251B1 (en) * | 2020-01-02 | 2024-07-31 | F. Hoffmann-La Roche AG | Method for determining the amount of a therapeutic antibody in the brain |
| CN113495141A (zh) * | 2020-03-20 | 2021-10-12 | 迈克生物股份有限公司 | 2019新型冠状病毒IgM抗体检测试剂盒 |
| JP7525762B2 (ja) * | 2020-05-18 | 2024-07-31 | ビオシオン インコーポレイテッド | Ｉｌ６ｒに結合する抗体及びその使用 |
| KR102626197B1 (ko) * | 2020-11-19 | 2024-01-18 | 바디텍메드(주) | 항 약물 항체의 수준을 정확하게 정량화하는 방법 |
| JP7062803B1 (ja) | 2021-03-31 | 2022-05-06 | 積水メディカル株式会社 | 抗薬物抗体測定方法 |
| CN114047343B (zh) * | 2022-01-13 | 2022-05-31 | 美迪西普亚医药科技(上海)有限公司 | 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用 |
| AU2024216670A1 (en) * | 2023-02-07 | 2025-07-31 | F. Hoffmann-La Roche Ag | Method for the detection of anti-aav particle antibodies |
| GB2643845A (en) * | 2023-04-20 | 2026-03-04 | Xentria Inc | Methods for detecting an anti-drug antibody (ADA) against an anti-TNF alpha antibody |
| CN120761634B (zh) * | 2025-09-02 | 2025-12-05 | 宁波熙宁检测技术有限公司 | 一种针对多特异性单克隆抗体药物的ada检测方法 |
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| RU2505603C2 (ru) | 2007-09-26 | 2014-01-27 | Чугаи Сейяку Кабусики Кайся | Антитело против рецептора il-6 |
| BRPI0817482B8 (pt) | 2007-10-02 | 2021-05-25 | Chugai Pharmaceutical Co Ltd | uso de um anticorpo do receptor da interleucina-6 (il-6) no tratamento da doença do enxerto versus hospedeiro (gvhd) |
| PL2202307T5 (pl) | 2007-10-15 | 2021-10-04 | Chugai Seiyaku Kabushiki Kaisha | Sposób wytwarzania przeciwciała |
| AU2008337904B2 (en) | 2007-12-15 | 2014-02-13 | F. Hoffmann-La Roche Ag | Distinguishing assay |
| PE20091174A1 (es) | 2007-12-27 | 2009-08-03 | Chugai Pharmaceutical Co Ltd | Formulacion liquida con contenido de alta concentracion de anticuerpo |
| DE102008005523A1 (de) | 2008-01-23 | 2009-07-30 | Robert Bosch Gmbh | Kraftstoffinjektor |
| CA2717614A1 (en) | 2008-03-11 | 2009-09-17 | Genentech, Inc. | Antibodies with enhanced adcc function |
| DE102008013899A1 (de) | 2008-03-12 | 2009-09-17 | F. Hoffmann-La Roche Ag | Verfahren zur Herstellung rekombinanter Proteine bei konstantem Gehalt von pCO2 im Medium |
| TW201503898A (zh) | 2008-06-05 | 2015-02-01 | Chugai Pharmaceutical Co Ltd | 神經浸潤抑制劑 |
| US8323649B2 (en) | 2008-11-25 | 2012-12-04 | Alderbio Holdings Llc | Antibodies to IL-6 and use thereof |
| SG178190A1 (en) | 2009-07-31 | 2012-03-29 | Shin Maeda | Cancer metastasis inhibitor |
| US20110053223A1 (en) | 2009-08-14 | 2011-03-03 | Robert Bayer | Cell culture methods to make antibodies with enhanced adcc function |
| US20110117087A1 (en) | 2009-10-26 | 2011-05-19 | Reinhard Franze | Method for the production of a glycosylated immunoglobulin |
| WO2011128096A1 (en) | 2010-04-16 | 2011-10-20 | Roche Diagnostics Gmbh | Polymorphism markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment |
| JP5904552B2 (ja) | 2010-05-28 | 2016-04-13 | 国立研究開発法人国立がん研究センター | 膵癌治療剤 |
| RS63800B1 (sr) | 2010-05-28 | 2022-12-30 | Chugai Pharmaceutical Co Ltd | Poboljšanje antitumorskog odgovora t ćelije |
| WO2011154139A2 (en) | 2010-06-07 | 2011-12-15 | Roche Diagnostics Gmbh | Gene expression markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment |
| KR101933197B1 (ko) | 2010-11-08 | 2018-12-27 | 제넨테크, 인크. | 피하 투여용 항―ｉｌ―6 수용체 항체 |
| CN103889555B (zh) | 2011-09-01 | 2018-10-26 | 中外制药株式会社 | 通过超滤制备包含高度浓缩的抗体的组合物的方法 |
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2014
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- 2014-07-01 RU RU2016101730A patent/RU2674996C2/ru active
- 2014-07-01 EP EP14734471.7A patent/EP3017303B1/en active Active
- 2014-07-01 KR KR1020157037229A patent/KR102248581B1/ko active Active
- 2014-07-01 MX MX2015016389A patent/MX363403B/es unknown
- 2014-07-01 WO PCT/EP2014/063891 patent/WO2015000865A1/en not_active Ceased
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2016
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2018
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| KR102248581B1 (ko) | 2021-05-06 |
| CA2913687A1 (en) | 2015-01-08 |
| HK1217759A1 (zh) | 2017-01-20 |
| JP2019207246A (ja) | 2019-12-05 |
| JP6761085B2 (ja) | 2020-09-23 |
| BR112015032960A8 (pt) | 2019-12-31 |
| CN105378480B (zh) | 2018-06-12 |
| JP6563910B2 (ja) | 2019-08-21 |
| CN105378480A (zh) | 2016-03-02 |
| RU2674996C2 (ru) | 2018-12-14 |
| US10168326B2 (en) | 2019-01-01 |
| US10761091B2 (en) | 2020-09-01 |
| WO2015000865A1 (en) | 2015-01-08 |
| BR112015032960B1 (pt) | 2021-01-05 |
| US20160313322A1 (en) | 2016-10-27 |
| MX2015016389A (es) | 2016-04-11 |
| US20190094216A1 (en) | 2019-03-28 |
| EP3017303B1 (en) | 2018-01-03 |
| KR20160029034A (ko) | 2016-03-14 |
| RU2016101730A3 (enExample) | 2018-05-15 |
| EP3017303A1 (en) | 2016-05-11 |
| RU2016101730A (ru) | 2017-08-09 |
| CA2913687C (en) | 2022-12-13 |
| JP2016530495A (ja) | 2016-09-29 |
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