EA200700345A1 - Обогащённое антитело для выявления микобактериальной инфекции, способы применения и диагностические тесты, применяющие такое антитело - Google Patents

Обогащённое антитело для выявления микобактериальной инфекции, способы применения и диагностические тесты, применяющие такое антитело

Info

Publication number
EA200700345A1
EA200700345A1 EA200700345A EA200700345A EA200700345A1 EA 200700345 A1 EA200700345 A1 EA 200700345A1 EA 200700345 A EA200700345 A EA 200700345A EA 200700345 A EA200700345 A EA 200700345A EA 200700345 A1 EA200700345 A1 EA 200700345A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibody
enriched
identification
methods
application
Prior art date
Application number
EA200700345A
Other languages
English (en)
Other versions
EA013228B1 (ru
Inventor
Владимир А. Кульчин
Елена В. Молокова
Джиль Л. Керрик
Original Assignee
Чемоджен, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Чемоджен, Инк. filed Critical Чемоджен, Инк.
Publication of EA200700345A1 publication Critical patent/EA200700345A1/ru
Publication of EA013228B1 publication Critical patent/EA013228B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Популяция обогащенных антител, высокоспецифичных к антигену поверхностного полисахарида микобактерий. В родственном воплощении, антитело обогащают путем индуцирования в окружении, которое поддерживает антигенно-активный антиген. Данные антитела могут использоваться в иммунореактивном окружении для выявления наличия микобактериальной инфекции в образце, взятом из субъекта.
EA200700345A 2004-07-20 2005-07-20 Способ получения обогащённого поликлонального антитела, высокоспецифичного к антигену поверхностного полисахарида липоарабиноманнана микобактерий, и способы его применения EA013228B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58941904P 2004-07-20 2004-07-20
PCT/US2005/025875 WO2006012413A1 (en) 2004-07-20 2005-07-20 Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same

Publications (2)

Publication Number Publication Date
EA200700345A1 true EA200700345A1 (ru) 2007-08-31
EA013228B1 EA013228B1 (ru) 2010-04-30

Family

ID=35432542

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700345A EA013228B1 (ru) 2004-07-20 2005-07-20 Способ получения обогащённого поликлонального антитела, высокоспецифичного к антигену поверхностного полисахарида липоарабиноманнана микобактерий, и способы его применения

Country Status (15)

Country Link
US (3) US7335480B2 (ru)
EP (1) EP1771475B1 (ru)
JP (1) JP4948402B2 (ru)
CN (1) CN101014622B (ru)
AP (1) AP2316A (ru)
AT (1) ATE500272T1 (ru)
AU (1) AU2005267111B2 (ru)
BR (1) BRPI0513596B8 (ru)
CA (1) CA2574432C (ru)
DE (1) DE602005026665D1 (ru)
EA (1) EA013228B1 (ru)
MX (1) MX2007000916A (ru)
UA (1) UA92721C2 (ru)
WO (1) WO2006012413A1 (ru)
ZA (1) ZA200700525B (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11273220B2 (en) 2016-02-10 2022-03-15 Rutgers, The State University Of New Jersey Anti-LAM and anti-PIM6/LAM monoclonal antibodies for diagnosis and treatment of Mycobacterium tuberculosis infections

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006012413A1 (en) 2004-07-20 2006-02-02 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
WO2008067497A2 (en) * 2006-11-29 2008-06-05 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
US20100317037A1 (en) * 2009-06-16 2010-12-16 Sina Biotechnical Co. Detection of Mycobacterium Tuberculosis Bacilli
US9315566B2 (en) 2011-01-24 2016-04-19 National University Of Singapore Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
US10830760B2 (en) 2017-12-20 2020-11-10 General Electric Company Device for rapid detection of tuberculosis-lipoarabinomannan (TB-LAM) with enhanced sensitivity
US10837962B2 (en) 2017-12-20 2020-11-17 General Electric Company Method and associated device for rapid detection of target biomolecules with enhanced sensitivity
US20210302424A1 (en) * 2018-07-19 2021-09-30 Rutgers, The State University Of New Jersey Methods for dual detection and differentiation of infection by mycobacterium tuberculosis complex and nontuberculous mycobacteria
WO2020045625A1 (ja) 2018-08-31 2020-03-05 富士フイルム株式会社 イムノクロマトグラフキットおよび結核菌の検出方法
CN111234026A (zh) * 2020-02-21 2020-06-05 首都医科大学附属北京胸科医院 特异性结合脂阿拉伯甘露聚糖的单克隆抗体及其在分枝杆菌检测中的应用

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
WO1992014155A1 (en) * 1991-02-12 1992-08-20 Dynagen, Inc. Monoclonal antibodies directed towards mycobacterial antigens
US6214789B1 (en) * 1993-03-12 2001-04-10 Xoma Corporation Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products
US5756327A (en) * 1994-09-13 1998-05-26 Cubist Pharmaceuticals, Inc. Recombinant mycobacterial isoleucyl-tRNA synthetase genes, tester strains and assays
AU1750197A (en) 1996-01-17 1997-08-11 Trustees Of Boston University Mycobacterium antigens and methods for their detection
GB9605083D0 (en) * 1996-03-11 1996-05-08 Royal Ordnance Plc Howitzer anchor spade
SE9600949D0 (sv) * 1996-03-12 1996-03-12 Stefan Svenson Method of diagnosing a mycobacterial disease and immunoassay kit
US6545130B2 (en) * 1997-06-04 2003-04-08 Albert Einstein College Of Medicine Of Yeshiva University Monoclonal antibodies to mycobacterium tuberculosis and a modified ELISA assay
ES2329651T3 (es) * 2000-03-01 2009-11-30 Binax, Inc. Metodo para detectar la presencia de una bacteria objetivo y un antigeno de carbohidrato de la misma.
US20040038201A1 (en) * 2002-01-22 2004-02-26 Whitehead Institute For Biomedical Research Diagnostic and therapeutic applications for biomarkers of infection
WO2006012413A1 (en) * 2004-07-20 2006-02-02 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
WO2008067497A2 (en) 2006-11-29 2008-06-05 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11273220B2 (en) 2016-02-10 2022-03-15 Rutgers, The State University Of New Jersey Anti-LAM and anti-PIM6/LAM monoclonal antibodies for diagnosis and treatment of Mycobacterium tuberculosis infections
US11707525B2 (en) 2016-02-10 2023-07-25 Rutgers, The State University Of New Jersey Anti-LAM and anti-PIM6/LAM monoclonal antibodies for diagnosis and treatment of Mycobacterium tuberculosis infections

Also Published As

Publication number Publication date
CA2574432A1 (en) 2006-02-02
WO2006012413A1 (en) 2006-02-02
BRPI0513596A (pt) 2008-05-13
EA013228B1 (ru) 2010-04-30
JP4948402B2 (ja) 2012-06-06
JP2008507544A (ja) 2008-03-13
EP1771475A1 (en) 2007-04-11
AU2005267111A1 (en) 2006-02-02
ZA200700525B (en) 2008-09-25
US20060127406A1 (en) 2006-06-15
BRPI0513596B8 (pt) 2021-07-27
BRPI0513596B1 (pt) 2018-02-06
AP2316A (en) 2011-11-04
EP1771475B1 (en) 2011-03-02
UA92721C2 (ru) 2010-12-10
US8057797B2 (en) 2011-11-15
CN101014622A (zh) 2007-08-08
DE602005026665D1 (de) 2011-04-14
MX2007000916A (es) 2007-07-09
US20080213806A1 (en) 2008-09-04
AU2005267111B2 (en) 2011-03-03
US7615222B2 (en) 2009-11-10
CA2574432C (en) 2015-05-26
ATE500272T1 (de) 2011-03-15
US20100210823A1 (en) 2010-08-19
CN101014622B (zh) 2011-12-28
US7335480B2 (en) 2008-02-26
AP2007003884A0 (en) 2007-02-28

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