BRPI0513596B8 - método e kit para detectar uma infecção micobacteriana em uma amostra de um indivíduo de interesse por meio da detecção de antígeno micobacteriano - Google Patents

método e kit para detectar uma infecção micobacteriana em uma amostra de um indivíduo de interesse por meio da detecção de antígeno micobacteriano

Info

Publication number
BRPI0513596B8
BRPI0513596B8 BRPI0513596A BRPI0513596A BRPI0513596B8 BR PI0513596 B8 BRPI0513596 B8 BR PI0513596B8 BR PI0513596 A BRPI0513596 A BR PI0513596A BR PI0513596 A BRPI0513596 A BR PI0513596A BR PI0513596 B8 BRPI0513596 B8 BR PI0513596B8
Authority
BR
Brazil
Prior art keywords
detecting
mycobacterial
sample
antigen
individual
Prior art date
Application number
BRPI0513596A
Other languages
English (en)
Inventor
V Molokova Elena
L Kerrick Jill
A Koulchin Vladimir
Original Assignee
Chemogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemogen Inc filed Critical Chemogen Inc
Publication of BRPI0513596A publication Critical patent/BRPI0513596A/pt
Publication of BRPI0513596B1 publication Critical patent/BRPI0513596B1/pt
Publication of BRPI0513596B8 publication Critical patent/BRPI0513596B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

anticorpo enriquecido para detecção de infecção micobacteriana, métodos de uso e teste diagnóstico empregando o mesmo. a tecnologia revelada provê uma população de anticorpos enriquecidos, altamente específicos para um antígeno de um polissacarídeo de superfície de mycobacterium. em uma concretização correlata, o anticorpo é enriquecido por ter sumido em um ambiente que mantém o antígeno antigenicamente ativo. esses anticorpos podem ser empregados em um ambiente imunorreativo para detectar a presença de infecção micobacteriana em uma amostra de um indivíduo.
BRPI0513596A 2004-07-20 2005-07-20 método e kit para detectar uma infecção micobacteriana em uma amostra de um indivíduo de interesse por meio da detecção de antígeno micobacteriano BRPI0513596B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58941904P 2004-07-20 2004-07-20
US60/589,419 2004-07-20
PCT/US2005/025875 WO2006012413A1 (en) 2004-07-20 2005-07-20 Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same

Publications (3)

Publication Number Publication Date
BRPI0513596A BRPI0513596A (pt) 2008-05-13
BRPI0513596B1 BRPI0513596B1 (pt) 2018-02-06
BRPI0513596B8 true BRPI0513596B8 (pt) 2021-07-27

Family

ID=35432542

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513596A BRPI0513596B8 (pt) 2004-07-20 2005-07-20 método e kit para detectar uma infecção micobacteriana em uma amostra de um indivíduo de interesse por meio da detecção de antígeno micobacteriano

Country Status (15)

Country Link
US (3) US7335480B2 (pt)
EP (1) EP1771475B1 (pt)
JP (1) JP4948402B2 (pt)
CN (1) CN101014622B (pt)
AP (1) AP2316A (pt)
AT (1) ATE500272T1 (pt)
AU (1) AU2005267111B2 (pt)
BR (1) BRPI0513596B8 (pt)
CA (1) CA2574432C (pt)
DE (1) DE602005026665D1 (pt)
EA (1) EA013228B1 (pt)
MX (1) MX2007000916A (pt)
UA (1) UA92721C2 (pt)
WO (1) WO2006012413A1 (pt)
ZA (1) ZA200700525B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101014622B (zh) 2004-07-20 2011-12-28 凯默根公司 用于检测分枝杆菌感染的富集抗体，应用方法和应用其的诊断检测
WO2008067497A2 (en) * 2006-11-29 2008-06-05 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
US20100317037A1 (en) * 2009-06-16 2010-12-16 Sina Biotechnical Co. Detection of Mycobacterium Tuberculosis Bacilli
SG10201600531TA (en) 2011-01-24 2016-02-26 Univ Singapore Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
RU2732502C2 (ru) 2016-02-10 2020-09-18 Ратгерс, Де Стейт Юниверсити Оф Нью Джерси Новые моноклональные антитела к LAM и PIM6/LAM для диагностики и лечения инфекций, вызванных Mycobacterium tuberculosis
US10837962B2 (en) 2017-12-20 2020-11-17 General Electric Company Method and associated device for rapid detection of target biomolecules with enhanced sensitivity
US10830760B2 (en) 2017-12-20 2020-11-10 General Electric Company Device for rapid detection of tuberculosis-lipoarabinomannan (TB-LAM) with enhanced sensitivity
EP3823670A4 (en) * 2018-07-19 2022-04-20 Rutgers, the State University of New Jersey METHODS FOR COMBINED DETECTION AND DIFFERENTIATION OF INFECTION BY MYCOBACTERIUM TUBERCULOSIS COMPLEX AND NON-TUBERCULOSIS MYCOBACTERIA
EP3845903A4 (en) 2018-08-31 2021-11-24 FUJIFILM Corporation IMMUNOCHROMATOGRAPHY KIT AND METHOD OF DETECTION OF MYCOBACTERIUM TUBERCULOSIS
CN111234026A (zh) * 2020-02-21 2020-06-05 首都医科大学附属北京胸科医院 特异性结合脂阿拉伯甘露聚糖的单克隆抗体及其在分枝杆菌检测中的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1423892A (en) * 1991-02-12 1992-09-07 Colorado State University Research Foundation Monoclonal antibodies directed towards mycobacterial antigens
US6214789B1 (en) 1993-03-12 2001-04-10 Xoma Corporation Treatment of mycobacterial diseases by administration of bactericidal/permeability-increasing protein products
US5756327A (en) 1994-09-13 1998-05-26 Cubist Pharmaceuticals, Inc. Recombinant mycobacterial isoleucyl-tRNA synthetase genes, tester strains and assays
WO1997026007A1 (en) 1996-01-17 1997-07-24 Trustees Of Boston University Mycobacterium antigens and methods for their detection
GB9605083D0 (en) * 1996-03-11 1996-05-08 Royal Ordnance Plc Howitzer anchor spade
SE9600949D0 (sv) 1996-03-12 1996-03-12 Stefan Svenson Method of diagnosing a mycobacterial disease and immunoassay kit
US6545130B2 (en) * 1997-06-04 2003-04-08 Albert Einstein College Of Medicine Of Yeshiva University Monoclonal antibodies to mycobacterium tuberculosis and a modified ELISA assay
AU2001241867B2 (en) * 2000-03-01 2005-05-19 Binax, Inc. Method for detecting the presence of target bacteria or a target component carbohydrate antigen thereof
US20040038201A1 (en) 2002-01-22 2004-02-26 Whitehead Institute For Biomedical Research Diagnostic and therapeutic applications for biomarkers of infection
CN101014622B (zh) 2004-07-20 2011-12-28 凯默根公司 用于检测分枝杆菌感染的富集抗体，应用方法和应用其的诊断检测
WO2008067497A2 (en) 2006-11-29 2008-06-05 Chemogen, Inc. Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same

Also Published As

Publication number Publication date
US7335480B2 (en) 2008-02-26
EP1771475B1 (en) 2011-03-02
EP1771475A1 (en) 2007-04-11
ZA200700525B (en) 2008-09-25
US20080213806A1 (en) 2008-09-04
WO2006012413A1 (en) 2006-02-02
AU2005267111B2 (en) 2011-03-03
CA2574432A1 (en) 2006-02-02
ATE500272T1 (de) 2011-03-15
UA92721C2 (ru) 2010-12-10
JP2008507544A (ja) 2008-03-13
AP2007003884A0 (en) 2007-02-28
US20060127406A1 (en) 2006-06-15
CN101014622B (zh) 2011-12-28
US8057797B2 (en) 2011-11-15
CA2574432C (en) 2015-05-26
US7615222B2 (en) 2009-11-10
DE602005026665D1 (de) 2011-04-14
AU2005267111A1 (en) 2006-02-02
CN101014622A (zh) 2007-08-08
JP4948402B2 (ja) 2012-06-06
US20100210823A1 (en) 2010-08-19
BRPI0513596A (pt) 2008-05-13
BRPI0513596B1 (pt) 2018-02-06
EA200700345A1 (ru) 2007-08-31
AP2316A (en) 2011-11-04
EA013228B1 (ru) 2010-04-30
MX2007000916A (es) 2007-07-09

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06H Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette]

Free format text: REF. A RPI NO 2154 DE 17/04/2012. ANULACAO DA EXIGENCIA 6.6 POR TER SIDO INDEVIDA. REQUERENTE NAO APRESENTOU RESPOSTA A EXIGENCIA CONFORME DISPOE A RESOLUCAO 207 DE 24/04/2009, ENTRETANTO, A RESPOSTA CONSTA NO FORMULARIO DE DEPOSITO.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/07/2005, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 18A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2732 DE 16-05-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.