BRPI0821747A8 - Método, ensaio imunocromatográfico e fita de teste imunocromatográfica para detecção do complexo de mycobacterium tuberculosis - Google Patents

Método, ensaio imunocromatográfico e fita de teste imunocromatográfica para detecção do complexo de mycobacterium tuberculosis

Info

Publication number
BRPI0821747A8
BRPI0821747A8 BRPI0821747A BRPI0821747A BRPI0821747A8 BR PI0821747 A8 BRPI0821747 A8 BR PI0821747A8 BR PI0821747 A BRPI0821747 A BR PI0821747A BR PI0821747 A BRPI0821747 A BR PI0821747A BR PI0821747 A8 BRPI0821747 A8 BR PI0821747A8
Authority
BR
Brazil
Prior art keywords
mycobacterium tuberculosis
immunochromatographic
detection
tuberculosis complex
assay
Prior art date
Application number
BRPI0821747A
Other languages
English (en)
Inventor
Namba Yasuharu
Original Assignee
Bl Co Ltd
Tauns Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bl Co Ltd, Tauns Co Ltd filed Critical Bl Co Ltd
Publication of BRPI0821747A2 publication Critical patent/BRPI0821747A2/pt
Publication of BRPI0821747A8 publication Critical patent/BRPI0821747A8/pt
Publication of BRPI0821747B1 publication Critical patent/BRPI0821747B1/pt
Publication of BRPI0821747B8 publication Critical patent/BRPI0821747B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/5695Mycobacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

MÉTODO, ENSAIO IMUNOCROMATOGRÁFICO E FITA DE TESTE IMUNOCROMATOGRÁFICA PARA DETECÇÃO DO COMPLEXO DE MYCOBACTERIUM TUBERCULOSIS A presente invenção refere-se a um método para detectar especificamente um antígeno da proteína MTP64 secretória complexoespecífica de Mycobacterium tuberculosis em uma amostra biológica, por meio do qual o diagnóstico da infecção com Mycobacterium tuberculosis é realizado rápida e seguramente com precisão mais alta que antes. Um anticorpo que reconhece um epitopo para a MPB64 localizado em qualquer uma das sequências de aminoácidos SEQ ID NOS: 2 a 4, particularmente um anticorpo monoclonal foi obtido. Deste modo, um imunoensaio utilizando o anticorpo, particularmente um imunoensaio do tipo sanduiche utilizando os primeiro e segundo anticorpos para a MPB64, particularmente um ensaio imunocromatográfico e uma fita de teste imunocromatográfica são fornecidos. Uma amostra biológica pode ser rapidamente submetida ao imunoensaio sem ficar em cultura ou após cultura por um período de tempo antes da bactéria do complexo Mycobacterium tuberculosis na amostra começar a crescer substancialmente. A amostra biológica pode ser pré-tratada através do tratamento para inativação de Mycobacterium tuberculosis, ou tratamento por dispersão ou solubilização.
BRPI0821747A 2007-12-28 2008-12-19 método, ensaio imunocromatográfico e fita de teste imunocromatográfica para detecção do complexo de mycobacterium tuberculosis BRPI0821747B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007-339376 2007-12-28
JP2007339376 2007-12-28
PCT/JP2008/073200 WO2009084481A1 (ja) 2007-12-28 2008-12-19 結核菌群の免疫検出法

Publications (4)

Publication Number Publication Date
BRPI0821747A2 BRPI0821747A2 (pt) 2015-06-16
BRPI0821747A8 true BRPI0821747A8 (pt) 2017-10-03
BRPI0821747B1 BRPI0821747B1 (pt) 2019-04-30
BRPI0821747B8 BRPI0821747B8 (pt) 2021-07-27

Family

ID=40824198

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0821747A BRPI0821747B8 (pt) 2007-12-28 2008-12-19 método, ensaio imunocromatográfico e fita de teste imunocromatográfica para detecção do complexo de mycobacterium tuberculosis

Country Status (8)

Country Link
US (1) US8541179B2 (pt)
EP (1) EP2226635B1 (pt)
JP (1) JP4943515B2 (pt)
CN (3) CN103123354B (pt)
BR (1) BRPI0821747B8 (pt)
HK (1) HK1152375A1 (pt)
RU (1) RU2473095C2 (pt)
WO (1) WO2009084481A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012088577A2 (pt) * 2010-12-29 2012-07-05 Universidade Federal De Minas Gerais - Ufmg Proteína recombinante de mycobacterium sp., teste imunodiagnóstico e vacina para tuberculose
ES2746565T3 (es) 2012-04-05 2020-03-06 Tauns Co Ltd Procedimiento y kit para la detección inmunológica de complejo de Mycobacterium tuberculosis
US8735091B2 (en) * 2012-05-17 2014-05-27 Biomerieux, Inc. Methods for inactivation and extraction of acid-fast bacteria for characterization and/or identification using mass spectrometry
JP6481192B2 (ja) * 2013-12-27 2019-03-13 地方独立行政法人大阪健康安全基盤研究所 クドア・セプテンプンクタータの迅速検出法
RU2594063C1 (ru) * 2015-04-27 2016-08-10 Федеральное государственное бюджетное научное учреждение "Центральный научно-исследовательский институт туберкулёза" Способ диагностики микобактерий туберкулёза
CN106526171A (zh) * 2015-09-11 2017-03-22 睿嘉生物科技股份有限公司 免疫检测套组
EP3225310A1 (fr) 2016-03-31 2017-10-04 Biomérieux Membranes d'analyse de dispositifs microfluidiques, réalisées en un matériau en fibre de verre
RU2645907C1 (ru) * 2016-09-07 2018-02-28 Общество с ограниченной ответственностью "Рикомед" Вязкость среды как инструмент контроля предела обнаружения иммунохроматографических тест-систем
US20210072235A1 (en) * 2017-12-22 2021-03-11 Sugentech, Inc. Method for diagnosing tuberculosis
CN108318694A (zh) * 2018-01-29 2018-07-24 厦门大学 一种采用免疫试纸条对抗原进行定量检测的方法
JP7403948B2 (ja) * 2018-10-31 2023-12-25 公益財団法人筑波メディカルセンター 試料の前処理方法
JP7395254B2 (ja) * 2019-02-25 2023-12-11 公益財団法人筑波メディカルセンター 微生物の検出方法
CN113789283A (zh) * 2021-10-20 2021-12-14 周玉美 一种快速培养结核分枝杆菌的培养基及其制备方法和应用
CN114813671B (zh) * 2022-04-06 2023-07-14 四川大学华西医院 基于金属离子和其纳米粒子选择性调控QDs和钙黄绿素荧光信号的分析方法及应用
CN114805586A (zh) * 2022-04-14 2022-07-29 天津华科泰生物技术有限公司 抗MxA单克隆抗体组合物及其应用

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JP2624759B2 (ja) * 1988-03-30 1997-06-25 味の素株式会社 Bcg菌由来のmpb64蛋白及びその製造法
JPH07110332A (ja) 1993-10-12 1995-04-25 Tetsuo Tomiyama 結核菌の検査試薬及び検出方法
US5658749A (en) * 1994-04-05 1997-08-19 Corning Clinical Laboratories, Inc. Method for processing mycobacteria
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US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6416962B1 (en) * 1995-11-20 2002-07-09 Kreatech Biotechnology B.V. Method and device for identifying a mycobacterium species responsible for a mycobacterial infection
JP4269006B2 (ja) 1997-09-30 2009-05-27 株式会社ビーエル 結核菌検出法
JP2001247094A (ja) * 2000-03-06 2001-09-11 Hisao Watanabe 熱風船
WO2002095411A1 (en) * 2001-05-18 2002-11-28 Virogates Aps A method of diagnosing or prognosticating major respiratory bacterial pathogens in a subject
CN1425775A (zh) * 2001-12-11 2003-06-25 李克生 结核抗体金标测试条及其制备方法
CN1312723C (zh) * 2003-06-18 2007-04-25 友达光电股份有限公司 等离子发光面板
JP2007316068A (ja) 2006-05-22 2007-12-06 Polaris Wireless Inc 無線端末の居場所の予測方法
CN100494352C (zh) * 2006-12-30 2009-06-03 华中农业大学 检测牛结核抗体的免疫胶体金试纸条及制备方法
JP4406656B2 (ja) * 2007-07-13 2010-02-03 株式会社ビーエル 結核菌検出法
CN101294964B (zh) 2007-11-27 2012-06-27 复旦大学附属华山医院 一种检测活动性结核病和结核潜伏感染的试剂和方法

Also Published As

Publication number Publication date
EP2226635A1 (en) 2010-09-08
WO2009084481A1 (ja) 2009-07-09
HK1152375A1 (en) 2012-02-24
RU2473095C2 (ru) 2013-01-20
CN103123353B (zh) 2014-11-12
BRPI0821747B8 (pt) 2021-07-27
CN101925819B (zh) 2013-06-12
BRPI0821747A2 (pt) 2015-06-16
CN103123354A (zh) 2013-05-29
CN103123353A (zh) 2013-05-29
US20100285506A1 (en) 2010-11-11
EP2226635A4 (en) 2012-07-04
EP2226635B1 (en) 2013-03-13
JP4943515B2 (ja) 2012-05-30
BRPI0821747B1 (pt) 2019-04-30
JPWO2009084481A1 (ja) 2011-05-19
US8541179B2 (en) 2013-09-24
CN101925819A (zh) 2010-12-22
RU2010131460A (ru) 2012-02-10
CN103123354B (zh) 2014-11-12

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: TAUNS CO., LTD. (JP)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 30/04/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 30/04/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/12/2008, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO