MX356269B - Uso de anticuerpos anti-cgrp y fragmentos de anticuerpo para prevenir o inhibir la fotofobia o aversion a la luz en sujetos en necesidad de los mismos, especialmente pacientes con migraña. - Google Patents

Uso de anticuerpos anti-cgrp y fragmentos de anticuerpo para prevenir o inhibir la fotofobia o aversion a la luz en sujetos en necesidad de los mismos, especialmente pacientes con migraña.

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Publication number
MX356269B
MX356269B MX2013013533A MX2013013533A MX356269B MX 356269 B MX356269 B MX 356269B MX 2013013533 A MX2013013533 A MX 2013013533A MX 2013013533 A MX2013013533 A MX 2013013533A MX 356269 B MX356269 B MX 356269B
Authority
MX
Mexico
Prior art keywords
cgrp
photophobia
antibodies
fragments
subjects
Prior art date
Application number
MX2013013533A
Other languages
English (en)
Other versions
MX2013013533A (es
Inventor
Robert Kovacevich Brian
F Garcia-Martinez Leon
A Latham John
F Russo Andrew
A Kaiser Eric
Recober Ana
Kuburas Adisa
C Raddant Ann
T L Smith Jeffrey
Original Assignee
Alderbio Holdings Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alderbio Holdings Llc filed Critical Alderbio Holdings Llc
Publication of MX2013013533A publication Critical patent/MX2013013533A/es
Publication of MX356269B publication Critical patent/MX356269B/es

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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
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Abstract

La presente invención se refiere a usos de un anticuerpo relacionado con el gen dela calcitonina (CGRP) o fragmento del anticuerpo para inhibir la fotofobia asociada a CGRP.
MX2013013533A 2011-05-20 2012-05-21 Uso de anticuerpos anti-cgrp y fragmentos de anticuerpo para prevenir o inhibir la fotofobia o aversion a la luz en sujetos en necesidad de los mismos, especialmente pacientes con migraña. MX356269B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161488660P 2011-05-20 2011-05-20
US201161496860P 2011-06-14 2011-06-14
PCT/US2012/038875 WO2012162257A2 (en) 2011-05-20 2012-05-21 Use of anti-cgrp antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers

Publications (2)

Publication Number Publication Date
MX2013013533A MX2013013533A (es) 2014-09-04
MX356269B true MX356269B (es) 2018-05-21

Family

ID=47175058

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013013533A MX356269B (es) 2011-05-20 2012-05-21 Uso de anticuerpos anti-cgrp y fragmentos de anticuerpo para prevenir o inhibir la fotofobia o aversion a la luz en sujetos en necesidad de los mismos, especialmente pacientes con migraña.

Country Status (16)

Country Link
US (3) US9708393B2 (es)
EP (2) EP2709663B1 (es)
JP (4) JP6374789B2 (es)
KR (2) KR101965461B1 (es)
CN (3) CN108014334B (es)
AU (3) AU2012258980B8 (es)
BR (1) BR112013029959A8 (es)
CA (2) CA2836800A1 (es)
CY (1) CY2022019I2 (es)
DK (1) DK2709663T3 (es)
EA (1) EA034747B1 (es)
IL (1) IL229434B (es)
MX (1) MX356269B (es)
NZ (1) NZ732970A (es)
SG (1) SG194973A1 (es)
WO (1) WO2012162257A2 (es)

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