MA52202A - Compositions d'érénumab et utilisations de celles-ci - Google Patents
Compositions d'érénumab et utilisations de celles-ciInfo
- Publication number
- MA52202A MA52202A MA052202A MA52202A MA52202A MA 52202 A MA52202 A MA 52202A MA 052202 A MA052202 A MA 052202A MA 52202 A MA52202 A MA 52202A MA 52202 A MA52202 A MA 52202A
- Authority
- MA
- Morocco
- Prior art keywords
- erenumab
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N2030/022—Column chromatography characterised by the kind of separation mechanism
- G01N2030/027—Liquid chromatography
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862651651P | 2018-04-02 | 2018-04-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA52202A true MA52202A (fr) | 2021-02-17 |
Family
ID=66248665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA052202A MA52202A (fr) | 2018-04-02 | 2019-04-01 | Compositions d'érénumab et utilisations de celles-ci |
Country Status (19)
Country | Link |
---|---|
US (2) | US11407838B2 (fr) |
EP (1) | EP3774881A1 (fr) |
JP (2) | JP2021519790A (fr) |
KR (1) | KR20200139720A (fr) |
CN (1) | CN111954678A (fr) |
AR (1) | AR114722A1 (fr) |
AU (1) | AU2019246983A1 (fr) |
BR (1) | BR112020019882A2 (fr) |
CA (1) | CA3095899A1 (fr) |
CL (2) | CL2020002519A1 (fr) |
EA (1) | EA202092335A1 (fr) |
IL (1) | IL277663A (fr) |
MA (1) | MA52202A (fr) |
MX (1) | MX2020010320A (fr) |
PH (1) | PH12020551618A1 (fr) |
SA (1) | SA520420261B1 (fr) |
SG (1) | SG11202009629YA (fr) |
TW (1) | TWI847980B (fr) |
WO (1) | WO2019195185A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2023120561A1 (fr) * | 2021-12-22 | 2023-06-29 |
Family Cites Families (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
US4927762A (en) | 1986-04-01 | 1990-05-22 | Cell Enterprises, Inc. | Cell culture medium with antioxidant |
ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
WO1993019180A1 (fr) | 1992-03-17 | 1993-09-30 | Ciba-Geigy Ag | Anticorps produits par genie genetique |
ATE265466T1 (de) | 1994-08-16 | 2004-05-15 | Human Genome Sciences Inc | Calcitoninrezeptor |
US5785682A (en) | 1995-03-22 | 1998-07-28 | Abbott Laboratories | Pre-filled syringe drug delivery system |
WO1998003534A1 (fr) | 1996-07-23 | 1998-01-29 | Smithkline Beecham Corporation | Facteur composant du recepteur du peptide apparente au gene de la calcitonine (houdc44) |
US6255455B1 (en) | 1996-10-11 | 2001-07-03 | The Trustees Of The University Of Pennsylvania | Rh(D)-binding proteins and magnetically activated cell sorting method for production thereof |
DK1308456T3 (da) | 1998-05-06 | 2007-12-27 | Genentech Inc | Antistofoprensning ved ionbytterkromatografi |
ES2228052T3 (es) | 1998-06-01 | 2005-04-01 | Genentech, Inc. | Separacion demonomeros de anticuerpos de sus multimeros utilizando cromatografia de intercambio de iones. |
FR2821080B1 (fr) | 2001-02-20 | 2003-12-19 | Sanofi Synthelabo | Anticorps specifique de l'adrenomedulline humaine, composition pharmaceutique le contenant, ses applications therapeutiques |
EP1438325B1 (fr) | 2001-09-27 | 2009-12-30 | Merck & Co., Inc. | Molecules d'adn isolees codant un recepteur humanise du peptide lie au gene de la calcitonine, animaux transgeniques non humains associes et methodes d'analyse |
US7658924B2 (en) | 2001-10-11 | 2010-02-09 | Amgen Inc. | Angiopoietin-2 specific binding agents |
AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
US20040110170A1 (en) | 2002-05-18 | 2004-06-10 | The Regents Of The University Of California | Cloning and characterization of calcitonin gene related peptide receptors |
PL375536A1 (en) | 2002-08-12 | 2005-11-28 | Birkir Sveinsson | Use of cgrp antagonist compounds for treatment of psoriasis |
US20040176577A1 (en) | 2002-09-10 | 2004-09-09 | Eva Rojer | Immunoassays for specific determination of SCCA isoforms |
WO2004097421A2 (fr) | 2003-04-29 | 2004-11-11 | Bayer Healthcare Ag | Diagnostics et traitements destines a des maladies associees au recepteur de type recepteur calcitonine (calcrl) |
WO2005077072A2 (fr) | 2004-02-11 | 2005-08-25 | Amylin Pharmaceuticals, Inc. | Polypeptides hybrides presentant des proprietes pouvant etre choisies |
AU2005310305A1 (en) | 2004-10-22 | 2006-06-08 | Amgen Inc. | Methods for refolding polypeptides |
KR101370253B1 (ko) | 2004-10-22 | 2014-03-05 | 암젠 인크 | 재조합 항체의 재접힘 방법 |
US7423128B2 (en) | 2004-11-03 | 2008-09-09 | Amgen Fremont Inc. | Anti-properdin antibodies, and methods for making and using same |
CN105085678B (zh) | 2004-12-21 | 2019-05-07 | 阿斯利康公司 | 血管生成素-2的抗体及其应用 |
WO2006134692A1 (fr) | 2005-06-16 | 2006-12-21 | Univ Shinshu | Agent angiogénétique contenant de l’adrénoméduline comme principe actif |
GB0521139D0 (en) | 2005-10-18 | 2005-11-23 | Univ Sheffield | Therapeutic agent |
US8168592B2 (en) | 2005-10-21 | 2012-05-01 | Amgen Inc. | CGRP peptide antagonists and conjugates |
BRPI0618705B8 (pt) | 2005-11-14 | 2021-05-25 | Labrys Biologics Inc | anticorpos antagonistas humanizados direcionados contra peptídeo relacionado ao gene da calcitonina, composição farmacêutica e uso dos mesmos |
WO2007076336A1 (fr) | 2005-12-22 | 2007-07-05 | Eli Lilly And Company | Traitement de la migraine avec des anticorps anti-cgrp |
WO2008112004A2 (fr) | 2006-08-03 | 2008-09-18 | Astrazeneca Ab | ANTICORPS DIRIGÉS CONTRE αVβ6 ET LEURS UTILISATIONS |
GB0708002D0 (en) | 2007-04-25 | 2007-06-06 | Univ Sheffield | Antibodies |
MX2010009724A (es) | 2008-03-04 | 2010-09-28 | Pfizer Ltd | Procedimientos de tratamiento del dolor inflamatorio-. |
FR2934597B1 (fr) | 2008-07-31 | 2013-04-19 | Univ Aix Marseille Ii | Anticorps se liant aux recepteurs de l'adrenomedulline et leurs utilisations comme medicament. |
CA2737045C (fr) * | 2008-11-20 | 2017-11-14 | Bruce Kabakoff | Formulations de proteine therapeutique |
JO3382B1 (ar) | 2008-12-23 | 2019-03-13 | Amgen Inc | أجسام مضادة ترتبط مع مستقبل cgrp بشري |
BRPI1006519A2 (pt) * | 2009-03-06 | 2016-08-09 | Genentech Inc | formulação de anticorpos |
AU2010275774B2 (en) * | 2009-07-24 | 2016-03-31 | F. Hoffmann-La Roche Ag | Optimizing the production of antibodies |
RU2535074C2 (ru) | 2009-08-28 | 2014-12-10 | Лэйбрис Байолоджикс, Инк. | Способы лечения висцеральной боли путем введения антител-антагонистов, направленных против пептида, связанного с геном кальцитонина |
SG10201408384PA (en) | 2009-12-18 | 2015-01-29 | Novartis Ag | Wash solution and method for affinity chromatography |
JOP20190250A1 (ar) | 2010-07-14 | 2017-06-16 | Regeneron Pharma | صيغ مستقرة تحتوي على الأجسام المضادة لمضاد عامل نمو الأعصاب |
CA2836800A1 (fr) | 2011-05-20 | 2012-11-29 | Alderbio Holdings Llc | Utilisation d'anticorps et de fragments d'anticorps anti-cgrp dans la prevention ou l'inhibition de la photophobie ou de l'aversion a la lumiere chez des sujets qui en ont besoin, en particulier des personnes souffrant de migraines |
US9783570B2 (en) | 2011-07-01 | 2017-10-10 | Hoffmann-La Roche Inc. | Method for separation of monomeric polypeptides from aggregated polypeptides |
EP2788097A4 (fr) * | 2011-12-07 | 2015-09-09 | Amgen Inc | Séparation d'isoforme de disulfure d'igg2 |
PT2791176T (pt) * | 2011-12-15 | 2018-11-05 | Prestige Biopharma Pte Ltd | Um método de purificação de anticorpos |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013158279A1 (fr) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Procédés de purification de protéines pour réduire des espèces acides |
EP3683237A1 (fr) | 2013-03-15 | 2020-07-22 | Amgen Inc. | Anticorps anti-pac1 humains |
WO2015006686A1 (fr) * | 2013-07-12 | 2015-01-15 | Genentech, Inc. | Solution d'optimisation d'entrée de chromatographie d'échange d'ions |
US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
RS65360B1 (sr) | 2014-03-21 | 2024-04-30 | Teva Pharmaceuticals Int Gmbh | Antagonistička antitela specifična za peptid genski srodan kalcitoninu i postupci njihove upotrebe |
US10556945B2 (en) | 2014-03-21 | 2020-02-11 | Teva Pharmaceuticals International Gmbh | Antagonist antibodies directed against calcitonin gene-related peptide and methods using same |
JP6956631B2 (ja) | 2014-09-15 | 2021-11-02 | アムジェン インコーポレイテッド | 二重特異性抗cgrp受容体/pac1受容体抗原結合タンパク質及びその使用 |
JOP20200116A1 (ar) * | 2015-04-24 | 2017-06-16 | Amgen Inc | طرق لعلاج أو الوقاية من الصداع النصفي |
AR104847A1 (es) * | 2015-06-17 | 2017-08-16 | Lilly Co Eli | Formulación de anticuerpo anti-cgrp |
-
2019
- 2019-04-01 AU AU2019246983A patent/AU2019246983A1/en active Pending
- 2019-04-01 KR KR1020207030828A patent/KR20200139720A/ko unknown
- 2019-04-01 MX MX2020010320A patent/MX2020010320A/es unknown
- 2019-04-01 JP JP2020553476A patent/JP2021519790A/ja active Pending
- 2019-04-01 CA CA3095899A patent/CA3095899A1/fr active Pending
- 2019-04-01 AR ARP190100860A patent/AR114722A1/es unknown
- 2019-04-01 CN CN201980024813.5A patent/CN111954678A/zh active Pending
- 2019-04-01 EA EA202092335A patent/EA202092335A1/ru unknown
- 2019-04-01 EP EP19718933.5A patent/EP3774881A1/fr active Pending
- 2019-04-01 BR BR112020019882-0A patent/BR112020019882A2/pt unknown
- 2019-04-01 US US16/372,291 patent/US11407838B2/en active Active
- 2019-04-01 MA MA052202A patent/MA52202A/fr unknown
- 2019-04-01 SG SG11202009629YA patent/SG11202009629YA/en unknown
- 2019-04-01 WO PCT/US2019/025223 patent/WO2019195185A1/fr active Application Filing
- 2019-04-02 TW TW108111646A patent/TWI847980B/zh active
-
2020
- 2020-09-29 IL IL277663A patent/IL277663A/en unknown
- 2020-09-29 CL CL2020002519A patent/CL2020002519A1/es unknown
- 2020-10-01 SA SA520420261A patent/SA520420261B1/ar unknown
- 2020-10-01 PH PH12020551618A patent/PH12020551618A1/en unknown
-
2022
- 2022-06-28 US US17/852,077 patent/US20220348673A1/en active Pending
-
2023
- 2023-02-17 CL CL2023000491A patent/CL2023000491A1/es unknown
- 2023-05-08 JP JP2023076664A patent/JP2023103323A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CN111954678A (zh) | 2020-11-17 |
CA3095899A1 (fr) | 2019-10-10 |
AR114722A1 (es) | 2020-10-07 |
EP3774881A1 (fr) | 2021-02-17 |
US20190300617A1 (en) | 2019-10-03 |
TWI847980B (zh) | 2024-07-11 |
SA520420261B1 (ar) | 2024-05-23 |
CL2020002519A1 (es) | 2021-04-05 |
AU2019246983A1 (en) | 2020-10-29 |
MX2020010320A (es) | 2021-01-08 |
SG11202009629YA (en) | 2020-10-29 |
IL277663A (en) | 2020-11-30 |
US11407838B2 (en) | 2022-08-09 |
KR20200139720A (ko) | 2020-12-14 |
BR112020019882A2 (pt) | 2021-01-05 |
US20220348673A1 (en) | 2022-11-03 |
JP2023103323A (ja) | 2023-07-26 |
CL2023000491A1 (es) | 2023-10-13 |
EA202092335A1 (ru) | 2021-01-22 |
JP2021519790A (ja) | 2021-08-12 |
PH12020551618A1 (en) | 2021-08-16 |
TW202003572A (zh) | 2020-01-16 |
WO2019195185A1 (fr) | 2019-10-10 |
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