MX338707B - Compuestos heterociclicos activadores de proteina cinasa activada por 5'-amp (ampk) y metodos para emplearlos. - Google Patents

Compuestos heterociclicos activadores de proteina cinasa activada por 5'-amp (ampk) y metodos para emplearlos.

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Publication number
MX338707B
MX338707B MX2013000575A MX2013000575A MX338707B MX 338707 B MX338707 B MX 338707B MX 2013000575 A MX2013000575 A MX 2013000575A MX 2013000575 A MX2013000575 A MX 2013000575A MX 338707 B MX338707 B MX 338707B
Authority
MX
Mexico
Prior art keywords
methods
ampk
same
heterocyclic compounds
activating
Prior art date
Application number
MX2013000575A
Other languages
English (en)
Other versions
MX2013000575A (es
Inventor
Dane Goff
David Carroll
Rajinder Singh
Donald Payan
Simon Shaw
Yasumichi Hotoshi
Original Assignee
Rigel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44504240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX338707(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Publication of MX2013000575A publication Critical patent/MX2013000575A/es
Publication of MX338707B publication Critical patent/MX338707B/es

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Abstract

Se describen compuestos piridínicos sustituidos así como también composiciones farmacéuticas y métodos de empleo. Una modalidad es un compuesto con la estructura (ver Fórmula) donde E, J, T, el sistema anular denominado "B", T, R3, R4, w y x son como se definen en la presente. En ciertas modalidades, un compuesto que se describe en la presente activa la vía AMPK, y se puede emplear para tratar trastornos y afecciones relacionados con el metabolismo.
MX2013000575A 2010-07-29 2011-07-29 Compuestos heterociclicos activadores de proteina cinasa activada por 5'-amp (ampk) y metodos para emplearlos. MX338707B (es)

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US20120028954A1 (en) 2012-02-02
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US20130267702A1 (en) 2013-10-10
UA112061C2 (uk) 2016-07-25
US8791136B2 (en) 2014-07-29
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US9266856B2 (en) 2016-02-23
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