MX338327B - Inhibidores de cdk. - Google Patents
Inhibidores de cdk.Info
- Publication number
- MX338327B MX338327B MX2013004681A MX2013004681A MX338327B MX 338327 B MX338327 B MX 338327B MX 2013004681 A MX2013004681 A MX 2013004681A MX 2013004681 A MX2013004681 A MX 2013004681A MX 338327 B MX338327 B MX 338327B
- Authority
- MX
- Mexico
- Prior art keywords
- cdk inhibitors
- cdk
- inhibitors
- formulae
- iii
- Prior art date
Links
- 229940043378 cyclin-dependent kinase inhibitor Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/499—Spiro-condensed pyrazines or piperazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40649810P | 2010-10-25 | 2010-10-25 | |
| PCT/US2011/057749 WO2012061156A1 (en) | 2010-10-25 | 2011-10-25 | Cdk inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013004681A MX2013004681A (es) | 2013-10-17 |
| MX338327B true MX338327B (es) | 2016-04-12 |
Family
ID=46024778
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013004681A MX338327B (es) | 2010-10-25 | 2011-10-25 | Inhibidores de cdk. |
| MX2020005498A MX385616B (es) | 2010-10-25 | 2011-10-25 | Inhibidores de cdk |
| MX2016004581A MX367795B (es) | 2010-10-25 | 2011-10-25 | Inhibidores de cdk. |
| MX2019010602A MX379532B (es) | 2010-10-25 | 2011-10-25 | Inhibidores de cdk. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020005498A MX385616B (es) | 2010-10-25 | 2011-10-25 | Inhibidores de cdk |
| MX2016004581A MX367795B (es) | 2010-10-25 | 2011-10-25 | Inhibidores de cdk. |
| MX2019010602A MX379532B (es) | 2010-10-25 | 2011-10-25 | Inhibidores de cdk. |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US8598186B2 (enExample) |
| EP (6) | EP3567042B1 (enExample) |
| JP (4) | JP5923509B2 (enExample) |
| KR (4) | KR102186969B1 (enExample) |
| CN (5) | CN103936745B (enExample) |
| AU (5) | AU2011323739B2 (enExample) |
| BR (1) | BR112013010018B1 (enExample) |
| CA (2) | CA2961937C (enExample) |
| CY (1) | CY1118004T1 (enExample) |
| DK (1) | DK2632467T3 (enExample) |
| ES (1) | ES2592515T3 (enExample) |
| HK (2) | HK1197067A1 (enExample) |
| HR (1) | HRP20161092T1 (enExample) |
| HU (1) | HUE030714T2 (enExample) |
| IL (5) | IL225940A0 (enExample) |
| LT (1) | LT2632467T (enExample) |
| MX (4) | MX338327B (enExample) |
| PL (1) | PL2632467T3 (enExample) |
| PT (1) | PT2632467T (enExample) |
| RS (1) | RS55135B1 (enExample) |
| RU (1) | RU2621674C2 (enExample) |
| SG (2) | SG10201508715YA (enExample) |
| SI (1) | SI2632467T1 (enExample) |
| SM (1) | SMT201600311B (enExample) |
| WO (1) | WO2012061156A1 (enExample) |
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| WO2010132725A2 (en) | 2009-05-13 | 2010-11-18 | The University Of North Carolina At Chapel Hill | Cyclin dependent kinase inhibitors and methods of use |
| US8691830B2 (en) | 2010-10-25 | 2014-04-08 | G1 Therapeutics, Inc. | CDK inhibitors |
| CN103501789A (zh) | 2010-11-17 | 2014-01-08 | 北卡罗来纳大学查珀尔希尔分校 | 通过抑制增殖性激酶cdk4和cdk6保护肾组织免于局部缺血 |
| EP2831080B1 (en) | 2012-03-29 | 2017-03-15 | Francis Xavier Tavares | Lactam kinase inhibitors |
| MY175254A (en) | 2012-04-26 | 2020-06-17 | G1 Therapeutics Inc | Synthesis of lactams |
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