MX338210B - Formas cristalinas de 5-cloro-n2-(2-isopropoxi-5-metil-4-piperidin -4-il-fenil)-n4-[2- (propan-2-sulfonil)-fenil]-pirimidin-2,4-diami na. - Google Patents

Formas cristalinas de 5-cloro-n2-(2-isopropoxi-5-metil-4-piperidin -4-il-fenil)-n4-[2- (propan-2-sulfonil)-fenil]-pirimidin-2,4-diami na.

Info

Publication number
MX338210B
MX338210B MX2013006952A MX2013006952A MX338210B MX 338210 B MX338210 B MX 338210B MX 2013006952 A MX2013006952 A MX 2013006952A MX 2013006952 A MX2013006952 A MX 2013006952A MX 338210 B MX338210 B MX 338210B
Authority
MX
Mexico
Prior art keywords
phenyl
crystalline forms
isopropoxy
diamine
chloro
Prior art date
Application number
MX2013006952A
Other languages
English (en)
Spanish (es)
Other versions
MX2013006952A (es
Inventor
Lili Feng
Piotr H Karpinski
Liladhar Murlidhar Waykole
Baoqing Gong
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45464892&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX338210(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2013006952A publication Critical patent/MX2013006952A/es
Publication of MX338210B publication Critical patent/MX338210B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Hydrogenated Pyridines (AREA)
MX2013006952A 2010-12-17 2011-12-15 Formas cristalinas de 5-cloro-n2-(2-isopropoxi-5-metil-4-piperidin -4-il-fenil)-n4-[2- (propan-2-sulfonil)-fenil]-pirimidin-2,4-diami na. MX338210B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201061424194P 2010-12-17 2010-12-17
PCT/US2011/065030 WO2012082972A1 (en) 2010-12-17 2011-12-15 Crystalline forms of 5-chloro-n2-(2-isopropoxy-5-methyl-4-piperidin-4-yl-phenyl)-n4[2-(propane-2-sulfonyl)-phenyl]-pyrimidine-2,4-diamine

Publications (2)

Publication Number Publication Date
MX2013006952A MX2013006952A (es) 2013-07-15
MX338210B true MX338210B (es) 2016-04-07

Family

ID=45464892

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013006952A MX338210B (es) 2010-12-17 2011-12-15 Formas cristalinas de 5-cloro-n2-(2-isopropoxi-5-metil-4-piperidin -4-il-fenil)-n4-[2- (propan-2-sulfonil)-fenil]-pirimidin-2,4-diami na.

Country Status (36)

Country Link
US (2) US9309229B2 (OSRAM)
EP (3) EP3453708B8 (OSRAM)
JP (1) JP5916752B2 (OSRAM)
KR (4) KR20190022903A (OSRAM)
CN (7) CN112125884A (OSRAM)
AR (2) AR084309A1 (OSRAM)
AU (1) AU2011343775B2 (OSRAM)
BR (1) BR112013015000A2 (OSRAM)
CA (1) CA2821102C (OSRAM)
CL (1) CL2013001723A1 (OSRAM)
CO (1) CO6801792A2 (OSRAM)
CY (2) CY1119474T1 (OSRAM)
DK (2) DK3121171T3 (OSRAM)
EC (1) ECSP13012770A (OSRAM)
ES (3) ES2696526T3 (OSRAM)
GT (1) GT201300153A (OSRAM)
HR (2) HRP20171477T1 (OSRAM)
HU (1) HUE041845T2 (OSRAM)
IL (1) IL226474A (OSRAM)
LT (2) LT3121171T (OSRAM)
MA (1) MA34771B1 (OSRAM)
MX (1) MX338210B (OSRAM)
MY (2) MY177742A (OSRAM)
NZ (1) NZ610713A (OSRAM)
PE (1) PE20140698A1 (OSRAM)
PH (1) PH12013501254A1 (OSRAM)
PL (2) PL2651918T3 (OSRAM)
PT (2) PT3121171T (OSRAM)
RS (1) RS57771B1 (OSRAM)
RU (2) RU2746159C2 (OSRAM)
SG (2) SG10201510082XA (OSRAM)
SI (2) SI3121171T1 (OSRAM)
TN (1) TN2013000216A1 (OSRAM)
TW (2) TWI576343B (OSRAM)
WO (1) WO2012082972A1 (OSRAM)
ZA (1) ZA201303599B (OSRAM)

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CN105294650A (zh) * 2014-08-01 2016-02-03 江苏奥赛康药业股份有限公司 一种Ceritinib化合物及其药物组合物
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WO2017152858A1 (zh) * 2016-03-11 2017-09-14 苏州晶云药物科技有限公司 色瑞替尼的晶型及其制备方法
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GB201915618D0 (en) 2019-10-28 2019-12-11 Univ Oslo ALK inhibitors for treatment of ALK-negative cancer and antibody-mediated diseases
EP4092021B1 (en) * 2020-01-17 2025-11-12 Xuanzhu Biopharmaceutical Co., Ltd. Crystal form of polycyclic anaplastic lymphoma kinase inhibitor
MX2022011768A (es) * 2020-03-30 2022-10-18 Jiangsu Yahong Meditech Co Ltd Forma cristalina del profarmaco de nitroxolina, la composicion farmaceutica que la contiene, y el metodo de preparacion y aplicacion de la misma.
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EP3328848A1 (en) 2015-07-28 2018-06-06 Zentiva, K.S. Solid forms of ceritinib free base
CN105061397B (zh) 2015-08-07 2018-01-02 武汉英普瑞医药科技有限公司 一种色瑞替尼的c型晶型及其制备方法与应用

Also Published As

Publication number Publication date
KR102325775B1 (ko) 2021-11-12
PH12013501254A1 (en) 2016-07-29
CL2013001723A1 (es) 2013-12-27
AR122395A2 (es) 2022-09-07
RS57771B1 (sr) 2018-12-31
TN2013000216A1 (en) 2014-11-10
DK3121171T3 (en) 2018-12-10
MY164810A (en) 2018-01-30
CN112125884A (zh) 2020-12-25
TWI576344B (zh) 2017-04-01
US9309229B2 (en) 2016-04-12
JP5916752B2 (ja) 2016-05-11
CN106008462A (zh) 2016-10-12
LT3121171T (lt) 2018-11-12
CA2821102A1 (en) 2012-06-21
PT3121171T (pt) 2018-11-27
TW201307299A (zh) 2013-02-16
IL226474A (en) 2016-03-31
RU2016136823A (ru) 2018-12-11
DK2651918T3 (en) 2017-10-23
WO2012082972A1 (en) 2012-06-21
GT201300153A (es) 2014-06-09
MY177742A (en) 2020-09-23
PL2651918T3 (pl) 2017-12-29
HRP20181737T1 (hr) 2018-12-28
JP2013545812A (ja) 2013-12-26
ES2696526T3 (es) 2019-01-16
CN107056751A (zh) 2017-08-18
CY1119474T1 (el) 2018-04-04
EP2651918B1 (en) 2017-07-12
SG10201510082XA (en) 2016-01-28
EP2651918A1 (en) 2013-10-23
CA2821102C (en) 2019-06-11
MA34771B1 (fr) 2013-12-03
CN114989139A (zh) 2022-09-02
MX2013006952A (es) 2013-07-15
ES2643016T3 (es) 2017-11-21
BR112013015000A2 (pt) 2016-08-09
TWI576343B (zh) 2017-04-01
EP3453708B8 (en) 2022-03-16
SG190856A1 (en) 2013-07-31
RU2016136823A3 (OSRAM) 2020-02-06
CY1121017T1 (el) 2019-12-11
RU2746159C2 (ru) 2021-04-08
KR20180032680A (ko) 2018-03-30
PE20140698A1 (es) 2014-06-11
KR20190022903A (ko) 2019-03-06
US20130274279A1 (en) 2013-10-17
ZA201303599B (en) 2014-02-26
EP3453708A1 (en) 2019-03-13
US20160175305A1 (en) 2016-06-23
PL3121171T3 (pl) 2019-01-31
CN106831716A (zh) 2017-06-13
SI3121171T1 (sl) 2018-11-30
IL226474A0 (en) 2013-07-31
CO6801792A2 (es) 2013-11-29
ECSP13012770A (es) 2013-10-31
HUE041845T2 (hu) 2019-05-28
LT2651918T (lt) 2017-10-10
PT2651918T (pt) 2017-10-17
EP3121171A1 (en) 2017-01-25
KR20130130022A (ko) 2013-11-29
KR20200039021A (ko) 2020-04-14
ES2905973T3 (es) 2022-04-12
EP3121171B1 (en) 2018-08-15
SI2651918T1 (sl) 2017-10-30
RU2013132947A (ru) 2015-01-27
EP3453708B1 (en) 2021-10-27
CN104262324A (zh) 2015-01-07
RU2599785C2 (ru) 2016-10-20
AU2011343775A1 (en) 2013-07-18
RU2599785C3 (ru) 2019-04-24
HRP20171477T1 (hr) 2017-11-17
AR084309A1 (es) 2013-05-08
AU2011343775B2 (en) 2015-12-03
TW201629021A (zh) 2016-08-16
CN103282359A (zh) 2013-09-04
NZ610713A (en) 2014-10-31

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