MX337357B - Excipiente para tableteado a base de lactosa y celulosa. - Google Patents

Excipiente para tableteado a base de lactosa y celulosa.

Info

Publication number
MX337357B
MX337357B MX2011002950A MX2011002950A MX337357B MX 337357 B MX337357 B MX 337357B MX 2011002950 A MX2011002950 A MX 2011002950A MX 2011002950 A MX2011002950 A MX 2011002950A MX 337357 B MX337357 B MX 337357B
Authority
MX
Mexico
Prior art keywords
lactose
cellulose
tableting aid
based tableting
aid
Prior art date
Application number
MX2011002950A
Other languages
English (en)
Other versions
MX2011002950A (es
Inventor
Eugen Schwarz
Gernot Warnke
Vera Fichtner
Original Assignee
Molkerei Meggle Wasserburg Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41413349&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX337357(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Molkerei Meggle Wasserburg Gmbh & Co Kg filed Critical Molkerei Meggle Wasserburg Gmbh & Co Kg
Publication of MX2011002950A publication Critical patent/MX2011002950A/es
Publication of MX337357B publication Critical patent/MX337357B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

La presente invención se refiere a un proceso para producir un granulado a base de lactosa y celulosa (derivado), un granulado que se obtiene por el proceso y su uso como un excipiente para tableteado.
MX2011002950A 2008-09-19 2009-09-21 Excipiente para tableteado a base de lactosa y celulosa. MX337357B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008047910A DE102008047910A1 (de) 2008-09-19 2008-09-19 Tablettierhilfsstoff auf Laktose- und Cellulosebasis
PCT/EP2009/062203 WO2010031866A1 (de) 2008-09-19 2009-09-21 Tablettierhilfsstoff auf laktose- und cellulosebasis

Publications (2)

Publication Number Publication Date
MX2011002950A MX2011002950A (es) 2011-08-03
MX337357B true MX337357B (es) 2016-02-29

Family

ID=41413349

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011002950A MX337357B (es) 2008-09-19 2009-09-21 Excipiente para tableteado a base de lactosa y celulosa.

Country Status (13)

Country Link
US (1) US8663684B2 (es)
EP (1) EP2344197B1 (es)
KR (1) KR101661256B1 (es)
CN (1) CN102202691B (es)
BR (1) BRPI0918530B1 (es)
CA (1) CA2737380C (es)
DE (1) DE102008047910A1 (es)
ES (1) ES2624231T3 (es)
MX (1) MX337357B (es)
NZ (1) NZ592331A (es)
UA (1) UA102865C2 (es)
WO (1) WO2010031866A1 (es)
ZA (1) ZA201101982B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008047910A1 (de) 2008-09-19 2010-03-25 Molkerei Meggle Wasserburg Gmbh & Co. Kg Tablettierhilfsstoff auf Laktose- und Cellulosebasis
CN102258495B (zh) * 2011-07-13 2013-01-30 石家庄四药有限公司 头孢丙烯片及其制备方法
PL2797581T3 (pl) * 2011-12-27 2020-10-05 Amgen (Europe) GmbH Formulacje (+)-2-[1-(3-etoksy-4-metoksy-fenylo)-2-metanosulfonylo-etylo]- 4acetyloaminoizoindolino-1,3-dionu
NZ747657A (en) 2012-11-02 2019-12-20 Murray And Poole Entpr Ltd Treatment or prevention of cardiovascular events via the administration of a colchicine derivative
MY198452A (en) 2013-04-16 2023-08-29 Murray And Poole Enterprises Ltd Sustained-release formulations of colchicine and methods of using same
CN114504559B (zh) * 2022-03-01 2023-05-05 安徽山河药用辅料股份有限公司 一种药用辅料乳糖纤维素共处理物的制备方法
WO2024060048A1 (zh) * 2022-09-21 2024-03-28 浙江汉脉医药科技有限公司 糖类缓释组合物及其制备方法

Family Cites Families (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3045488A1 (de) 1980-12-03 1982-07-01 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von stabilisierten kallikreinhaltigen tabletten
DE3505433A1 (de) * 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
DE3506276C1 (de) 1985-02-22 1986-04-24 Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring Direkttablettiermittel
DD249186A1 (de) 1986-05-26 1987-09-02 Univ Halle Wittenberg Herstellungsverfahren einer neuen glibenclamid-arzneiform mit hoher bioverfuegbarkeit
EP0610848B1 (de) 1993-02-11 1997-05-21 Hoechst Aktiengesellschaft Verfahren zur Herstellung von dichtgesinterten keramischen Bauteilen aus Siliziumnitrid mit hoher mechanischer Festigkeit
CZ289649B6 (cs) 1994-07-22 2002-03-13 Krka, Tovarna Zdravil. P.O. Pevné lékové formy se spolehlivým uvolňováním aktivní sloľky alprazolamu a způsob jejich přípravy
DE19602757A1 (de) 1996-01-26 1997-07-31 Boehringer Mannheim Gmbh Feste Instant-Release-Darreichungsformen und Verfahren zu ihrer Herstellung
AU2068797A (en) 1996-01-29 1997-08-20 Edward Mendell Co. Inc. Sustained release excipient
US5762961A (en) 1996-02-09 1998-06-09 Quadrant Holdings Cambridge Ltd. Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof
CA2274832A1 (en) * 1996-12-12 1998-06-18 Dds Drug Delivery Service Gesellschaft Zur Forderung Der Forschung In Ph Armazeutischer Technologie Und Biopharmazie Mbh Preparation in form of a matrix material-auxiliary agent compound containing optionally an active substance
DE19651734C2 (de) 1996-12-12 1999-05-12 Dds Drug Delivery Service Ges Zubereitung in Form eines Polymer-Hilfsstoff-Compounds und/oder eines Polymer-Wirkstoff-Compounds und Verfahren zu dessen Herstellung sowie dessen Verwendung zur Herstellung von Tabletten und/oder anderen größeren Matrixeinheiten
DE19749897C1 (de) 1997-11-12 1999-08-26 Dds Drug Delivery Service Ges Zubereitung in Form eines Lipid-Hilfsstoff-Compounds und/oder eines Lipid-Wirkstoff-Compounds und Verfahren zu dessen Herstellung sowie dessen Verwendung zur Herstellung von Tabletten und/oder anderen größeren Matrixeinheiten
CA2209868C (en) 1997-08-15 2001-08-14 Bernard Charles Sherman Pharmaceutical compositions comprising cefuroxime axetil
EE200000186A (et) 1997-11-03 2001-04-16 Janssen Pharmaceutica N.V. Osake, selliste osakeste valmistamismeetod ja kasutamine, farmatseutiline doosivorm ja selle valmistamismeetod, tahke dispersioon ja farmatseutiline pakend
US6168805B1 (en) 1998-05-07 2001-01-02 Endo Pharmaceuticals, Inc. Aqueous process for manufacturing paroxetine solid dispersions
PE20000559A1 (es) 1998-05-27 2000-07-05 Merck & Co Inc Formulacion de tabletas comprimidas de efavirenz
EP1332757B1 (en) 1998-05-27 2012-06-13 Merck Sharp & Dohme Corp. Efavirenz compressed tablet formulation
MA26693A1 (fr) 1998-09-28 2004-12-20 Glaxo Group Ltd Compositions pour administration par voie buccale
EP1124541B1 (de) 1998-09-30 2003-11-26 Basf Aktiengesellschaft Verwendung von wasserlöslichen oder wasserdispergierbaren polyether-haltigen pfropfpolymerisaten als überzugsmittel, bindemittel und/oder filmbildender hilfsstoff in pharmazeutischen darreichungsformen
US20040013613A1 (en) 2001-05-18 2004-01-22 Jain Rajeev A Rapidly disintegrating solid oral dosage form
ID29270A (id) 1998-11-20 2001-08-16 Rtp Pharma Inc Partikel-partikel mikro yang distabilkan oleh fosfolipid yang dapat menyebar
US6716453B1 (en) 1999-05-20 2004-04-06 Verion, Inc. Method for increasing the active loading of compressible composition forms
CZ20014379A3 (cs) 1999-06-11 2002-08-14 Ranbaxy Laboratories Limited Kompozice k maskování chuti a způsob její přípravy
UA72922C2 (uk) 1999-08-03 2005-05-16 Ліллі Айкос Ллк ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ З <font face="Symbol">b</font>-КАРБОЛІНОМ (ВАРІАНТИ) ТА СПОСІБ ЛІКУВАННЯ СЕКСУАЛЬНОЇ ДИСФУНКЦІЇ
US6419956B1 (en) 1999-12-30 2002-07-16 Ancile Pharmaceuticals Odor-masking coating for a pharmaceutical preparation
DE50100265D1 (de) 2000-03-23 2003-07-03 Basf Drucksysteme Gmbh Verwendung von Pfropfcopolymeren zur Herstellung lasergravierbarer Reliefdruckelementen
US6761901B1 (en) 2000-05-02 2004-07-13 Enzrel Inc. Liposome drug delivery
US6316029B1 (en) 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
US20020001617A1 (en) 2000-05-26 2002-01-03 Chang-Hyun Lee Rapidly disintegrating tablet and process for the manufacture thereof
US6413590B1 (en) 2000-05-31 2002-07-02 Rexam Graphics Inc. Glossy ink jet medium
JP3415835B2 (ja) 2000-06-30 2003-06-09 山之内製薬株式会社 口腔内速崩壊錠およびその製造法
ES2215696T3 (es) 2000-07-13 2004-10-16 Vitatene, S.A. Metodo para la produccion de una formulacion dispersable en agua que contiene carotenoides.
DE60036205T2 (de) 2000-07-27 2008-05-21 Roquette Frères Granulat bestehend aus Stärke und Laktose
IN192750B (es) 2000-12-15 2004-05-15 Ranbaxy Lab Ltd
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
US6610326B2 (en) 2001-02-16 2003-08-26 Andrx Corporation Divalproex sodium tablets
SE0101329D0 (sv) 2001-04-12 2001-04-12 Astrazeneca Ab Pharmaceutical formulation
WO2002100407A1 (en) 2001-06-12 2002-12-19 Smartrix Technologies Inc. Itraconazole granulations: pharmaceutical formulations for oral administration and method of preparing same
US20040241247A1 (en) 2001-09-04 2004-12-02 Sheskey Paul J Process for dispersing a fluid in solid particles
JP2005506323A (ja) 2001-09-05 2005-03-03 ベクトゥラ・リミテッド 経口送達用機能性散剤
DE10152351B4 (de) 2001-10-18 2005-09-22 Schering Ag Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat
US6753017B2 (en) 2001-11-07 2004-06-22 Jrs Pharma Lp Process for preparing dry extracts
WO2003048666A1 (en) 2001-11-29 2003-06-12 Penwest Pharmaceutical Company Process for co-spray drying liquid herbal extracts with dry silicified mcc
US20030206978A1 (en) 2001-11-29 2003-11-06 Bob Sherwood Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose
US7179488B2 (en) 2001-11-29 2007-02-20 Bob Sherwood Process for co-spray drying liquid herbal extracts with dry silicified MCC
EP1509204A4 (en) 2001-11-29 2005-07-13 Rettenmaier & Soehne Gmbh & Co AGGLOMERATED PARTICLES WITH AN ACTIVE SUBSTANCE PREPARED WITH MELTED MICROCRYSTALLINE CELLULOSE
EP1467745A2 (en) 2002-01-10 2004-10-20 Lupin Limited Herbal composition for treating various disorders including psoriasis, a process for preparation thereof and method for treatment of such disorders
DE10207427A1 (de) 2002-02-21 2003-09-04 Basf Ag Schnelllöslicher Filmüberzug basierend auf Polyvinylalkohol-Polyether-Pfropfcopolymeren in Kombination mit Hydroxy-, Amid-, oder Esterfunktionen enthaltenden Komponenten
ES2327034T3 (es) 2002-03-26 2009-10-23 Euro-Celtique S.A. Composiciones recubiertas con gel de liberacion sostenida.
WO2003086343A2 (en) 2002-04-05 2003-10-23 Cadila Healthcare Limited Fast disintegrating oral dosage forms
MY128945A (en) * 2002-04-16 2007-03-30 Kowa Co Solid dispersion composition
NZ537253A (en) 2002-05-22 2007-09-28 Boehringer Ingelheim Pharma Coated pharmaceutical compositions containing flibanserin polymorph A
US20040037869A1 (en) 2002-08-16 2004-02-26 Douglas Cleverly Non-animal product containing veterinary formulations
GB0219516D0 (en) 2002-08-21 2002-10-02 Phoqus Ltd Fast dissolving and taste masked oral dosage form comprising sildenafil
US20040097484A1 (en) 2002-11-14 2004-05-20 Marc Cantillion Once a day galantamine pharmaceutical compositions and methods of use
EP1575604B1 (en) 2002-12-19 2006-12-06 Council Of Scientific And Industrial Research Antiulcer herbal composition(s)
JP2006513238A (ja) 2002-12-19 2006-04-20 ファルマシア・コーポレーション 吸湿性薬物を含む非‐吸湿性製剤
CN100339127C (zh) 2002-12-30 2007-09-26 科学和工业研究委员会 止咳、镇咳和润喉草药制剂的研制
EP1594479A1 (en) 2003-01-31 2005-11-16 Ranbaxy Laboratories Limited Stable oral benzimidazole compositions and processes for their preparation
WO2004082664A1 (en) 2003-03-21 2004-09-30 Ranbaxy Laboratories Limited Water-soluble tablets of metformin
WO2004089343A1 (en) 2003-04-09 2004-10-21 Ranbaxy Laboratories Limited Water soluble tablets
KR100503949B1 (ko) 2003-04-28 2005-07-26 주식회사유한양행 염산 온단세트론의 쓴맛을 효과적으로 은폐한 경구용 구강속붕해정 조성물
DE10319450A1 (de) 2003-04-30 2004-11-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung des Telmisartan Natriumsalzes
EP1648411A4 (en) 2003-07-10 2010-03-10 Glaxosmithkline Llc PHARMACEUTICAL COMPOSITIONS
TW200507882A (en) 2003-07-17 2005-03-01 Kyowa Hakko Kogyo Kk Solid formulations
WO2005009407A2 (en) 2003-07-29 2005-02-03 Ranbaxy Laboratories Limited Oral pharmaceutical formulations of olanzapine
KR100604034B1 (ko) 2003-10-08 2006-07-24 주식회사유한양행 암로디핀 유리염기를 함유한 구강 속붕해정 및 그의 조성물
WO2005041941A2 (en) 2003-11-03 2005-05-12 Zentiva, A.S. Valsartan containing formulation
WO2005051489A2 (en) 2003-11-28 2005-06-09 Ranbaxy Laboratories Limited Fast dissolving solid oral dosage forms of galanthamine
US20050142193A1 (en) 2003-12-31 2005-06-30 Lijuan Tang Galantamine formulations
US20050191349A1 (en) 2003-12-31 2005-09-01 Garth Boehm Galantamine formulations
US20060222677A1 (en) 2004-01-14 2006-10-05 Bianca Baroli Method of protecting sensitive molecules from a photo-polymerizing environment
WO2005082330A2 (en) 2004-02-19 2005-09-09 Ranbaxy Laboratories Limited Co-precipitated amorphous cefditoren pivoxil and dosage forms comprising the same
WO2005082331A2 (en) 2004-02-26 2005-09-09 Ranbaxy Laboratories Limited Extended release tablets of clarithromycin
CA2569964A1 (en) 2004-06-10 2005-12-29 Duramed Pharmaceuticals, Inc. Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same
WO2005123041A1 (en) 2004-06-18 2005-12-29 Yuhan Corporation Oral dispersible tablet composition of amoxycillin and/or clavulanic acid comprising a surface-modified sodium bicarbonate
US20060127479A1 (en) 2004-10-08 2006-06-15 Natrajan Kumaraperumal Solvent free taste masked pharmaceutical compositions
WO2006101536A1 (en) 2004-11-04 2006-09-28 Akina, Inc. Fast-melting tablets having taste-masking and sustained release properties
US20060159747A1 (en) 2004-12-17 2006-07-20 Boehringer Ingelheim International Gmbh Telmisartan and hydrochlorothiazide combination therapy
CA2601755C (en) 2005-02-03 2014-07-29 Nycomed Pharma As Melt granulation of a composition containing a calcium-containing compound
BRPI0606187A2 (pt) 2005-02-25 2009-06-09 Hoffmann La Roche comprimidos com capacidade de dispersão da substáncia do fármaco melhorada
GB0504203D0 (en) 2005-03-01 2005-04-06 Novartis Ag Organic compounds
WO2006113631A2 (en) 2005-04-18 2006-10-26 Rubicon Research Pvt. Ltd. Bioenhanced compositions
US20070014853A1 (en) 2005-07-15 2007-01-18 Ilan Zalit Pharmaceutical dosage form containing novel pharmaceutical granulate
JP2009511627A (ja) 2005-10-17 2009-03-19 マリンクロッド・インコーポレイテッド 錠剤マトリックスにおけるゾルピデムの多形転移
UA95093C2 (uk) 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
PL1842534T3 (pl) 2006-02-24 2012-05-31 Teva Pharma Tabletki bursztynianu metoprololu o przedłużonym uwalnianiu oraz sposoby ich wytwarzania
WO2007096906A2 (en) 2006-02-27 2007-08-30 Panacea Biotec Ltd. Novel buccoadhesive compositions and process of preparation thereof
GB0610570D0 (en) 2006-05-27 2006-07-05 Pliva Istrazivanje I Razvoj D Novel formulation
US20100297226A1 (en) * 2006-06-01 2010-11-25 Dexcel Pharma Technologies Ltd. Multiple unit pharmaceutical formulation
US8568785B2 (en) 2006-07-19 2013-10-29 Asahi Kasei Chemicals Corporation Process for producing spherical base granule comprising easily water-soluble drug
CN100438917C (zh) * 2006-07-20 2008-12-03 山东聊城阿华制药有限公司 一种微晶纤维素乳糖的制备方法
DE102008047910A1 (de) 2008-09-19 2010-03-25 Molkerei Meggle Wasserburg Gmbh & Co. Kg Tablettierhilfsstoff auf Laktose- und Cellulosebasis

Also Published As

Publication number Publication date
US8663684B2 (en) 2014-03-04
WO2010031866A1 (de) 2010-03-25
CA2737380C (en) 2017-04-11
CN102202691A (zh) 2011-09-28
DE102008047910A8 (de) 2010-07-08
ES2624231T3 (es) 2017-07-13
KR20110063549A (ko) 2011-06-10
CA2737380A1 (en) 2010-03-25
ZA201101982B (en) 2011-11-30
MX2011002950A (es) 2011-08-03
NZ592331A (en) 2012-10-26
US20110207826A1 (en) 2011-08-25
UA102865C2 (ru) 2013-08-27
EP2344197B1 (de) 2017-04-05
EP2344197A1 (de) 2011-07-20
BRPI0918530B1 (pt) 2019-06-04
KR101661256B1 (ko) 2016-09-30
BRPI0918530A2 (pt) 2015-12-08
CN102202691B (zh) 2014-03-26
DE102008047910A1 (de) 2010-03-25

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