WO2012134086A3 - 조직재생용 3차원 나노섬유 지지체 및 그 제조방법 - Google Patents

조직재생용 3차원 나노섬유 지지체 및 그 제조방법 Download PDF

Info

Publication number
WO2012134086A3
WO2012134086A3 PCT/KR2012/001925 KR2012001925W WO2012134086A3 WO 2012134086 A3 WO2012134086 A3 WO 2012134086A3 KR 2012001925 W KR2012001925 W KR 2012001925W WO 2012134086 A3 WO2012134086 A3 WO 2012134086A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
tissue repair
nanofiber scaffold
dimensional nanofiber
scaffold
Prior art date
Application number
PCT/KR2012/001925
Other languages
English (en)
French (fr)
Other versions
WO2012134086A2 (ko
Inventor
정성린
권일근
김천호
양대혁
이정복
박하나
Original Assignee
경희대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 경희대학교 산학협력단 filed Critical 경희대학교 산학협력단
Priority to US14/008,408 priority Critical patent/US9242024B2/en
Publication of WO2012134086A2 publication Critical patent/WO2012134086A2/ko
Publication of WO2012134086A3 publication Critical patent/WO2012134086A3/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/36—After-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/05—Alcohols; Metal alcoholates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/14—Polymer mixtures characterised by other features containing polymeric additives characterised by shape
    • C08L2205/16—Fibres; Fibrils
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Composite Materials (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Artificial Filaments (AREA)
  • Nonwoven Fabrics (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)

Abstract

본 발명은 조직재생용 지지체에 관한 것으로, 더욱 상세하게는 초음파 처리(ultra-sonication)를 통해 간단한 방법으로 두께와 다공도(porosity)를 증가시킬 수 있는 조직재생용 3차원 나노섬유 지지체 및 그 제조방법에 관한 것이다.
PCT/KR2012/001925 2011-03-29 2012-03-16 조직재생용 3차원 나노섬유 지지체 및 그 제조방법 WO2012134086A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US14/008,408 US9242024B2 (en) 2011-03-29 2012-03-16 Three-dimensional nanofiber scaffold for tissue repair and preparation method thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0028363 2011-03-29
KR20110028363A KR101186093B1 (ko) 2011-03-29 2011-03-29 조직재생용 3차원 나노섬유 지지체 및 그 제조방법

Publications (2)

Publication Number Publication Date
WO2012134086A2 WO2012134086A2 (ko) 2012-10-04
WO2012134086A3 true WO2012134086A3 (ko) 2013-01-03

Family

ID=46932056

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/001925 WO2012134086A2 (ko) 2011-03-29 2012-03-16 조직재생용 3차원 나노섬유 지지체 및 그 제조방법

Country Status (3)

Country Link
US (1) US9242024B2 (ko)
KR (1) KR101186093B1 (ko)
WO (1) WO2012134086A2 (ko)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101527469B1 (ko) * 2013-11-04 2015-06-11 연세대학교 산학협력단 다양한 삼차원 구조를 갖는 다공성 섬유 마이크로 구조체의 제조방법
US9132405B2 (en) 2014-02-12 2015-09-15 Ut-Battelle, Llc Method of synthesizing silica nanofibers using sound waves
KR101453796B1 (ko) * 2014-03-14 2014-10-27 동아대학교 산학협력단 나노-마이크로 하이브리드섬유 기반 세포배양 구조체 및 이를 포함하는 에세이칩
US11033659B2 (en) * 2014-09-29 2021-06-15 Board Of Regents Of The University Of Nebraska Nanofiber structures and methods of synthesis and use thereof
ES2584405A1 (es) * 2016-06-08 2016-09-27 Universitat Politècnica De València Compuesto no tejido bioelastómero
AU2017335828B2 (en) 2016-09-28 2023-07-13 Board Of Regents Of The University Of Nebraska Nanofiber structures and methods of use thereof
WO2018227078A1 (en) 2017-06-09 2018-12-13 Board Of Regents Of The University Of Nebraska Nanofiber structures and methods of use thereof
KR101947154B1 (ko) * 2017-06-23 2019-02-12 포항공과대학교 산학협력단 3차원 전기방사 스캐폴드 제조 방법 및 제조 장치
KR101943307B1 (ko) * 2017-06-29 2019-01-29 강원대학교산학협력단 높은 비표면적을 가지는 다공성 나노투과막 기반의 생체신호 측정용 생체전극 및 그의 제조방법
EP3684726A4 (en) * 2017-09-19 2021-06-30 Board of Regents of the University of Nebraska NANOFIBER STRUCTURES AND METHODS OF USING THEM
KR102199703B1 (ko) 2018-10-26 2021-01-11 계명대학교 산학협력단 3d 인쇄를 이용한 다층 바이오 스캐폴드 및 이를 제작하는 방법
KR102265451B1 (ko) * 2018-11-30 2021-06-15 한국생산기술연구원 3차원 섬유형 스캐폴드 및 이의 제조방법
KR102364168B1 (ko) 2019-12-05 2022-02-17 부산대학교 산학협력단 골조직 재생 지지체 및 이의 제조 방법
KR102125979B1 (ko) 2020-02-04 2020-06-25 주식회사 나노바이오시스템 섬유아세포 배양 지지체의 선택방법 및 체외 배양 방법
US20210246575A1 (en) * 2020-02-07 2021-08-12 University Of Georgia Research Foundation, Inc. Methods and devices for making nanofibers and nanofiber scaffolds
KR102499287B1 (ko) 2020-07-09 2023-02-10 전남대학교산학협력단 조직재생을 위한 기능성 플라즈마 멀티스케일 패치 개발
CN115282334A (zh) * 2022-01-10 2022-11-04 上海市第六人民医院 一种压电式氨基酸生物支架及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090034202A (ko) * 2007-10-02 2009-04-07 주식회사 에이엠오 식물성 천연 추출물 또는 식물성 천연 정유를 함유하는나노섬유 및 이의 제조방법
KR20090041271A (ko) * 2007-10-23 2009-04-28 재단법인서울대학교산학협력재단 조직공학용 나노섬유 지지체의 공극 구조 조절 방법 및그를 이용하여 제조된 조직공학용 지지체
KR20090127371A (ko) * 2007-03-29 2009-12-10 이 아이 듀폰 디 네모아 앤드 캄파니 용융 방사에 의한 나노섬유의 제조
KR20110009702A (ko) * 2008-05-13 2011-01-28 리써치 트라이앵글 인스티튜트 다공질 및 비다공질 나노구조체 및 이의 용도

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011107495A1 (en) * 2010-03-02 2011-09-09 Total Petrochemicals Research Feluy Nanocomposites with improved homogeneity

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090127371A (ko) * 2007-03-29 2009-12-10 이 아이 듀폰 디 네모아 앤드 캄파니 용융 방사에 의한 나노섬유의 제조
KR20090034202A (ko) * 2007-10-02 2009-04-07 주식회사 에이엠오 식물성 천연 추출물 또는 식물성 천연 정유를 함유하는나노섬유 및 이의 제조방법
KR20090041271A (ko) * 2007-10-23 2009-04-28 재단법인서울대학교산학협력재단 조직공학용 나노섬유 지지체의 공극 구조 조절 방법 및그를 이용하여 제조된 조직공학용 지지체
KR20110009702A (ko) * 2008-05-13 2011-01-28 리써치 트라이앵글 인스티튜트 다공질 및 비다공질 나노구조체 및 이의 용도

Also Published As

Publication number Publication date
US9242024B2 (en) 2016-01-26
US20140024760A1 (en) 2014-01-23
KR101186093B1 (ko) 2012-09-27
WO2012134086A2 (ko) 2012-10-04

Similar Documents

Publication Publication Date Title
WO2012134086A3 (ko) 조직재생용 3차원 나노섬유 지지체 및 그 제조방법
EP2774203B8 (en) Method for the preparation of catalyst-coated membranes
IL231769A (en) METHOD OF PRODUCING 4,4-DIPLORO-4,3-DIHYDROISOQUINOULIN DERIVATIVES
EP2694269A4 (en) LIGNIN COMPOSITIONS, METHODS FOR PRODUCING THE COMPOSITIONS, METHODS OF USING THE LIGNIN COMPOSITIONS, AND PRODUCTS COMPRISING THE SAME
EP2762499A4 (en) PROCESS FOR PRODUCING CELLULOSE NANOFIBERS
EP2665696A4 (en) PROCESS FOR THE PREPARATION OF 2,3,3,3-TETRAFLUOR-2-PROPENE
WO2013046060A9 (en) Paper and methods of making paper
EP2745919A4 (en) COMPOSITE SEMI-PERMEABLE MEMBRANE
EP2674034A4 (en) METHOD FOR PRODUCING CRYSTAL OIL AND CRYSTAL OIL PRODUCED BY THIS PROCESS
EP2730959A4 (en) OPTICAL CONNECTING ELEMENT, OPTICAL CONNECTING STRUCTURE AND METHOD FOR PRODUCING THE OPTICAL CONNECTING ELEMENT
EP2692739A4 (en) METHOD FOR PRODUCING CELLULOSE AFFAIRS
WO2014041560A3 (en) Process for the preparation of teneligliptin
EP2716396A4 (en) HOLLOWED CROPPED PLATE, MANUFACTURING PROCESS AND BURNER FOR A GAS TURBINE
EP2753738A4 (en) METHOD FOR PRODUCING FIBROUS YARN, FIBROUS YARN AND USE OF FIBROUS YARN
HK1206938A1 (en) Process for the preparation of 3-chloro-4,5,6-trifluoro- picolinonitrile 3--456--
EP2634378A4 (en) LOW PRESSURE STEAM TURBINE
EP2860050A4 (en) COUPLING STRUCTURE, COUPLING ELEMENT HAVING COUPLING STRUCTURE, AND METHOD FOR PRODUCING COUPLING ELEMENT HAVING COUPLING STRUCTURE
EP2662482A4 (en) FIBER CANVAS, PREPARATION METHOD THEREFOR, AND FILTER INCLUDING FIBER CANVAS
EP2894143A4 (en) METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE 2,3-DIHYDROFARNESAL
WO2011110624A3 (de) β-HYDROXYALKYLAMIDE, EIN VERFAHREN ZU IHRER HERSTELLUNG SOWIE DER VERWENDUNG
EP2698470A4 (en) METHOD FOR PRODUCING A FIBROUS AND FIBROUS MATERIAL
EP2851359A4 (en) PROCESS FOR PRODUCING 4,4 "-DIHIDROXY-M-TERPHENYLS
EP2876155A4 (en) PROCESS FOR THE PREPARATION OF 2,3-BANDANDIOL USING IMPROVED STRAINS OF RAOULTELLA PLANTICOLA
MX360870B (es) Catalizadores para la preparación de poliamida de moldeo, procedimiento para su preparación y su uso.
WO2013092672A3 (en) Method for recombinant production of labyrinthopeptins and functional derivatives thereof

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12764253

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 14008408

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 12764253

Country of ref document: EP

Kind code of ref document: A2