WO2012134086A3 - Three-dimensional nanofiber scaffold for tissue repair and preparation method thereof - Google Patents
Three-dimensional nanofiber scaffold for tissue repair and preparation method thereof Download PDFInfo
- Publication number
- WO2012134086A3 WO2012134086A3 PCT/KR2012/001925 KR2012001925W WO2012134086A3 WO 2012134086 A3 WO2012134086 A3 WO 2012134086A3 KR 2012001925 W KR2012001925 W KR 2012001925W WO 2012134086 A3 WO2012134086 A3 WO 2012134086A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- preparation
- tissue repair
- nanofiber scaffold
- dimensional nanofiber
- scaffold
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/36—After-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/05—Alcohols; Metal alcoholates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
- C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
- C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/14—Polymer mixtures characterised by other features containing polymeric additives characterised by shape
- C08L2205/16—Fibres; Fibrils
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Dispersion Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Artificial Filaments (AREA)
- Nonwoven Fabrics (AREA)
- Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
Abstract
The present invention relates to a scaffold for tissue repair, and more specifically to a three-dimensional nanofiber scaffold for tissue repair which can increase thickness and porosity of tissue using a simple method through ultra-sonication, and a preparation method thereof.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/008,408 US9242024B2 (en) | 2011-03-29 | 2012-03-16 | Three-dimensional nanofiber scaffold for tissue repair and preparation method thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2011-0028363 | 2011-03-29 | ||
KR20110028363A KR101186093B1 (en) | 2011-03-29 | 2011-03-29 | Fibrous 3-dimensional scaffold for tissue regeneration and method for manufacturing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012134086A2 WO2012134086A2 (en) | 2012-10-04 |
WO2012134086A3 true WO2012134086A3 (en) | 2013-01-03 |
Family
ID=46932056
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2012/001925 WO2012134086A2 (en) | 2011-03-29 | 2012-03-16 | Three-dimensional nanofiber scaffold for tissue repair and preparation method thereof |
Country Status (3)
Country | Link |
---|---|
US (1) | US9242024B2 (en) |
KR (1) | KR101186093B1 (en) |
WO (1) | WO2012134086A2 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101527469B1 (en) * | 2013-11-04 | 2015-06-11 | 연세대학교 산학협력단 | A Method for Fabrication of Porous fiber microstructure with various 3-dimensional Structures |
US9132405B2 (en) | 2014-02-12 | 2015-09-15 | Ut-Battelle, Llc | Method of synthesizing silica nanofibers using sound waves |
KR101453796B1 (en) * | 2014-03-14 | 2014-10-27 | 동아대학교 산학협력단 | Nano-micro hybridfiber-based cell culture construct and assay chip comprising the same |
CA2962927C (en) | 2014-09-29 | 2023-04-25 | Board Of Regents Of The University Of Nebraska | Nanofiber structures and methods of synthesis and use thereof |
ES2584405A1 (en) * | 2016-06-08 | 2016-09-27 | Universitat Politècnica De València | Non-woven bioelastomer compound (Machine-translation by Google Translate, not legally binding) |
AU2017335828B2 (en) | 2016-09-28 | 2023-07-13 | Board Of Regents Of The University Of Nebraska | Nanofiber structures and methods of use thereof |
US11738116B2 (en) | 2017-06-09 | 2023-08-29 | Board Of Regents Of The University Of Nebraska | Expanded nanofiber structures comprising electrospun nanofibers and a plurality of holes and methods of making and use thereof |
KR101947154B1 (en) * | 2017-06-23 | 2019-02-12 | 포항공과대학교 산학협력단 | Fabrication method and device for three-dimensional electrospun scaffold |
KR101943307B1 (en) * | 2017-06-29 | 2019-01-29 | 강원대학교산학협력단 | Flexible Bioelectrode based on Nanoporous Membrane with High Specific Surface Area for Bio-signal Acquisition And Manufacturing Method Thereof |
WO2019060393A1 (en) * | 2017-09-19 | 2019-03-28 | Board Of Regents Of The University Of Nebraska | Nanofiber structures and methods of use thereof |
KR102199703B1 (en) | 2018-10-26 | 2021-01-11 | 계명대학교 산학협력단 | Multi-layer bio-scaffold using 3D printing and method of manufacturing the same |
KR102265451B1 (en) * | 2018-11-30 | 2021-06-15 | 한국생산기술연구원 | 3-Dimensional fibrous scaffold, and method for preparing the same |
KR102364168B1 (en) | 2019-12-05 | 2022-02-17 | 부산대학교 산학협력단 | Scaffolds for bone regeneration and method for producing the same |
KR102125979B1 (en) | 2020-02-04 | 2020-06-25 | 주식회사 나노바이오시스템 | Cell culture scaffold for tissue regeneration and kit including the same |
US20210246575A1 (en) * | 2020-02-07 | 2021-08-12 | University Of Georgia Research Foundation, Inc. | Methods and devices for making nanofibers and nanofiber scaffolds |
KR102499287B1 (en) | 2020-07-09 | 2023-02-10 | 전남대학교산학협력단 | Plasma-assisted flexible multi-scale topographic patches for engineering cellular behavior and tissue regeneration |
CN115282334A (en) * | 2022-01-10 | 2022-11-04 | 上海市第六人民医院 | Piezoelectric type amino acid biological scaffold and preparation method thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20090034202A (en) * | 2007-10-02 | 2009-04-07 | 주식회사 에이엠오 | Nanofibers comprising naturalplant extract or naturalplant essential oil and method for producing the same |
KR20090041271A (en) * | 2007-10-23 | 2009-04-28 | 재단법인서울대학교산학협력재단 | Method of controlling pore structure of nanofirous scaffold for tissue engineering and scaffold using the same |
KR20090127371A (en) * | 2007-03-29 | 2009-12-10 | 이 아이 듀폰 디 네모아 앤드 캄파니 | Production of nanofibers by melt spinning |
KR20110009702A (en) * | 2008-05-13 | 2011-01-28 | 리써치 트라이앵글 인스티튜트 | Porous and non-porous nanostructures and application thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20130008542A (en) * | 2010-03-02 | 2013-01-22 | 토탈 리서치 앤드 테크놀로지 펠루이 | Nanocomposites with improved homogeneity |
-
2011
- 2011-03-29 KR KR20110028363A patent/KR101186093B1/en active IP Right Grant
-
2012
- 2012-03-16 US US14/008,408 patent/US9242024B2/en not_active Expired - Fee Related
- 2012-03-16 WO PCT/KR2012/001925 patent/WO2012134086A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20090127371A (en) * | 2007-03-29 | 2009-12-10 | 이 아이 듀폰 디 네모아 앤드 캄파니 | Production of nanofibers by melt spinning |
KR20090034202A (en) * | 2007-10-02 | 2009-04-07 | 주식회사 에이엠오 | Nanofibers comprising naturalplant extract or naturalplant essential oil and method for producing the same |
KR20090041271A (en) * | 2007-10-23 | 2009-04-28 | 재단법인서울대학교산학협력재단 | Method of controlling pore structure of nanofirous scaffold for tissue engineering and scaffold using the same |
KR20110009702A (en) * | 2008-05-13 | 2011-01-28 | 리써치 트라이앵글 인스티튜트 | Porous and non-porous nanostructures and application thereof |
Also Published As
Publication number | Publication date |
---|---|
WO2012134086A2 (en) | 2012-10-04 |
US20140024760A1 (en) | 2014-01-23 |
KR101186093B1 (en) | 2012-09-27 |
US9242024B2 (en) | 2016-01-26 |
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