MX2022003568A - Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía. - Google Patents

Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.

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Publication number
MX2022003568A
MX2022003568A MX2022003568A MX2022003568A MX2022003568A MX 2022003568 A MX2022003568 A MX 2022003568A MX 2022003568 A MX2022003568 A MX 2022003568A MX 2022003568 A MX2022003568 A MX 2022003568A MX 2022003568 A MX2022003568 A MX 2022003568A
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Mexico
Prior art keywords
energy
genetically engineered
engineered bacterium
fermentation pathway
buk
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Application number
MX2022003568A
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English (en)
Inventor
James Bruce Yarnton Haycock Behrendorff
Alexander Paul Mueller
Michael Kopke
Ryan Edward Hill
Rasmus Overgaard Jensen
Darmawi Juminaga
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Lanzatech Nz Inc
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Publication date
Application filed by Lanzatech Nz Inc filed Critical Lanzatech Nz Inc
Publication of MX2022003568A publication Critical patent/MX2022003568A/es

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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
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    • C12Y102/07—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with an iron-sulfur protein as acceptor (1.2.7)
    • C12Y102/07005—Aldehyde ferredoxin oxidoreductase (1.2.7.5)
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    • C12Y203/01008—Phosphate acetyltransferase (2.3.1.8)
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    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
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Abstract

La presente invención se refiere a una bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía y métodos relacionados a esta. En particular, la invención proporciona una bacteria que comprende una fosfato butiriltransferasa (Ptb) y una butirato cinasa (Buk) (Ptb-Buk) que actúa en sustratos no nativos para producir una amplia variedad de productos e intermediarios. En ciertas modalidades, la invención se refiere a la introducción de Ptb-Buk en un microorganismo que se fija a C1 capaz de producir productos a partir de un sustrato gaseoso.
MX2022003568A 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía. MX2022003568A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562240850P 2015-10-13 2015-10-13
PCT/US2016/056926 WO2017066498A1 (en) 2015-10-13 2016-10-13 Genetically engineered bacterium comprising energy-generating fermentation pathway

Publications (1)

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MX2022003568A true MX2022003568A (es) 2023-06-13

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MX2023003058A MX2023003058A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2018004642A MX2018004642A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2022003568A MX2022003568A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2021003330A MX2021003330A (es) 2015-10-13 2018-04-13 Bacteria dise?ada por ingenieria genetica que comprende una trayectoria de fermentacion que genera energia.

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MX2023003058A MX2023003058A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2018004642A MX2018004642A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.

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US (3) US9738875B2 (es)
EP (2) EP3362567A4 (es)
JP (2) JP6905518B2 (es)
KR (2) KR20210037002A (es)
CN (2) CN108884467A (es)
AU (2) AU2016339989B2 (es)
BR (1) BR112018007338A2 (es)
CA (6) CA3151149C (es)
EA (2) EA202190729A1 (es)
MX (4) MX2023003058A (es)
MY (1) MY194651A (es)
WO (1) WO2017066498A1 (es)
ZA (5) ZA201802346B (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA40644A (fr) * 2014-09-17 2016-03-24 Global Bioenergies Procédés pour produire de l'acide 3-hydroxy-3-méthylbutyrique
US11291693B2 (en) 2015-06-25 2022-04-05 Synlogic Operating Company, Inc. Bacteria engineered to treat metabolic diseases
EP3362567A4 (en) * 2015-10-13 2019-03-27 Lanzatech New Zealand Limited GENETICALLY MODIFIED BACTERIUM COMPRISING AN ENERGY-EFFICIENT FERMENTATION PATHWAY
GB201603915D0 (en) * 2016-03-07 2016-04-20 Chain Biotechnology Ltd Method and microbes for the production of chiral compounds
JP7502029B2 (ja) 2016-05-14 2024-06-18 ランザテク，インコーポレイテッド 修飾されたアルデヒド：フェレドキシンオキシドレダクターゼ活性を有する微生物および関連方法
US11539066B2 (en) 2016-11-22 2022-12-27 The Penn State Research Foundation Devices and methods for generating electrical current from methane
CN107177609B (zh) * 2017-05-15 2020-12-11 大连理工大学 一种fruB基因过表达的重组梭菌、其构建方法及应用
CN107083406B (zh) * 2017-05-27 2021-02-02 浙江华睿生物技术有限公司 (r)-3-羟基丁酸的生产方法
WO2019006255A1 (en) * 2017-06-30 2019-01-03 Invista North America S.A.R.L. METHODS, MATERIALS, SYNTHETIC HOSTS AND REAGENTS FOR HYDROCARBON BIOSYNTHESIS AND DERIVATIVES
MY193827A (en) 2017-09-08 2022-10-27 Lanzatech Inc Processes and systems for metabolite production using hydrogen rich c1-containing substrates
BR112020005108A2 (pt) * 2017-09-28 2020-09-15 Lanzatech, Inc. bactéria wood-ljungdahl de ocorrência não natural, e, método de produção de um produto
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
EP3719121A4 (en) * 2017-11-30 2021-12-15 Toray Industries, Inc. GENE-MODIFIED MICROORGANISM FOR THE PRODUCTION OF 3-HYDROXYADIPIC ACID, -HYDROMUCONIC ACID AND / OR ADIPIC ACID AND THE MANUFACTURING METHOD FOR THESE CHEMICAL PRODUCTS
EP3728614A4 (en) 2017-12-19 2021-11-24 Lanzatech, Inc. MICROORGANISMS AND METHODS FOR THE BIOLOGICAL MANUFACTURING OF EHTYLENE GLYCOL
WO2019147702A1 (en) * 2018-01-23 2019-08-01 Lanzatech, Inc. Two-step fermenation process for production of a product
WO2019152753A1 (en) * 2018-02-01 2019-08-08 Invista Textiles (U.K.) Limited Methods and materials for the biosynthesis of beta hydroxy fatty acid anions and/or derivatives thereof and/or compounds related thereto
JP7273834B2 (ja) 2018-02-12 2023-05-15 ランザテク，インコーポレイテッド 炭素変換効率を改善するためのプロセス
CN111918957A (zh) 2018-04-20 2020-11-10 朗泽科技有限公司 间歇电解流
CN109251940B (zh) * 2018-10-30 2020-10-16 浙江华睿生物技术有限公司 一种产β-羟基-β-甲基丁酸工程菌的构建方法
SG11202105051SA (en) 2018-11-19 2021-06-29 Lanzatech Inc Integration of fermentation and gasification
CA3129223C (en) 2019-02-08 2023-07-11 Lanzatech, Inc. Process for recovering close boiling products
EP3942058A1 (en) 2019-03-20 2022-01-26 Global Bioenergies Improved means and methods for producing isobutene from acetyl-coa
FR3096373A1 (fr) * 2019-05-24 2020-11-27 IFP Energies Nouvelles Outil genetique optimisé pour modifier les bacteries
EP3997235A4 (en) 2019-07-11 2024-05-08 Lanzatech, Inc. PROCESSES FOR OPTIMIZING GAS USE
US20220258100A1 (en) * 2019-07-16 2022-08-18 San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation Products of manufacture and methods for methane capturing using biofiltration
CN112280723B (zh) * 2019-07-23 2022-08-19 清华大学 联产1,3-丙二醇和1,3-丁二醇的重组菌及其应用
CN112280722B (zh) * 2019-07-23 2022-03-08 清华大学 用于生产光学纯1,3-丁二醇的重组菌及其应用
JP7376041B2 (ja) * 2019-09-11 2023-11-08 公益財団法人地球環境産業技術研究機構 形質転換体及びそれを用いる１，３－ブタンジオールの製造方法
CN111089914A (zh) * 2019-11-07 2020-05-01 河北首朗新能源科技有限公司 微生物发酵生产乙醇中代谢物的高效液相检测方法
WO2021130128A1 (en) * 2019-12-23 2021-07-01 Co2Bioclean Gmbh Novel bioplastics
JP7475598B2 (ja) 2020-03-04 2024-04-30 大阪瓦斯株式会社 １，３－ブタンジオールの製造方法
CN111220762A (zh) * 2020-03-24 2020-06-02 河北首朗新能源科技有限公司 一种乙醇梭菌蛋白中有机物的含量的检测方法及应用
MX2022013570A (es) * 2020-04-29 2022-11-30 Lanzatech Inc Produccion fermentativa de b-cetoadipato a partir de sustratos gaseosos.
CA3180978C (en) 2020-06-06 2024-02-06 Ching LEANG Microorganism with knock-in at acetolactate decarboxylase gene locus
JP2023542338A (ja) * 2020-09-25 2023-10-06 ランザテク，インコーポレイテッド 組換え微生物及びそのための使用
KR102443037B1 (ko) 2020-10-23 2022-09-14 한국과학기술연구원 에탄올을 포함하는 합성 가스로부터 2,3-부탄디올 제조용 배지 조성물 및 이를 이용한 2,3-부탄디올 생산 방법
CA3195088C (en) 2021-02-08 2024-04-23 Fungmin Liew Recombinant microorganisms and their use in the production of 3-hydroxypropionate [3-hp]
CN115369048B (zh) * 2021-05-17 2023-10-20 华东理工大学 一种产玉米黄质的解脂耶氏酵母基因工程菌及其构建方法和应用
TW202307202A (zh) 2021-08-06 2023-02-16 美商朗澤科技有限公司 用於改良乙二醇之生物產生的微生物及方法
CN116376856B (zh) * 2022-04-06 2023-11-03 深圳蓝晶生物科技有限公司 表达乙酰乙酰辅酶a还原酶变体的工程化微生物及提高pha产量的方法
EP4279586A4 (en) 2022-04-06 2024-02-28 Shenzhen Bluepha Biosciences Co., Ltd. MODIFIED MICROORGANISM EXPRESSING AN ACETOACETYL REDUCTASE COENZYME VARIANT AND METHOD FOR INCREASING PHA YIELD

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593886A (en) 1992-10-30 1997-01-14 Gaddy; James L. Clostridium stain which produces acetic acid from waste gases
UA72220C2 (uk) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання
CN1217001C (zh) * 2002-01-04 2005-08-31 清华大学 一种生产d－(－)－3－羟基丁酸的方法
CN101432434B (zh) * 2005-09-29 2015-03-11 布特马斯先进生物燃料公司 4碳醇的发酵生产
NZ546496A (en) 2006-04-07 2008-09-26 Lanzatech New Zealand Ltd Gas treatment process
US7704723B2 (en) 2006-08-31 2010-04-27 The Board Of Regents For Oklahoma State University Isolation and characterization of novel clostridial species
NZ553984A (en) 2007-03-19 2009-07-31 Lanzatech New Zealand Ltd Alcohol production process
KR101114918B1 (ko) * 2007-08-09 2012-02-15 주식회사 엘지화학 재조합 미생물을 이용한 광학활성（ｓ）-3-하이드록시부탄산 및（ｓ）-3-하이드록시부티레이트 에스테르의 제조방법
KR101042242B1 (ko) * 2007-09-07 2011-06-17 한국과학기술원 1,4-부탄디올 생성능을 가지는 변이체 및 이를 이용한1,4-부탄디올의 제조방법
BRPI0820556B1 (pt) 2007-11-13 2016-03-22 Lanzatech New Zealand Ltd bactéria e métodos para uso das mesmas
ES2656790T3 (es) * 2008-03-27 2018-02-28 Genomatica, Inc. Microorganismos para la producción de ácido adípico y otros compuestos
EA018720B1 (ru) 2008-06-09 2013-10-30 Ланзатек Нью Зиленд Лимитед Способ получения бутандиола с помощью анаэробной микробной ферментации
PT2304040T (pt) 2008-07-04 2017-11-21 Scientist Of Fortune Sa Produção de alcenos por descarboxilação enzimática de ácidos 3-hidroxi-alcanoicos
WO2010022763A1 (en) 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
EP2382312A2 (en) * 2008-12-30 2011-11-02 Danisco US Inc. Methods of producing isoprene and a co-product
MX2012003025A (es) * 2009-09-09 2012-06-27 Genomatica Inc Microorganismos y metodos para la co-produccion de isopropanol con alcoholes, dioles y acidos primarios.
EP2295593A1 (en) 2009-09-15 2011-03-16 Philippe Marliere Method for the enymatic production of 3-hydroxy-3-methylbutyric acid from acetone and acetyl-CoA
SG181607A1 (en) * 2009-12-10 2012-07-30 Genomatica Inc Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
EP2336341A1 (en) 2009-12-21 2011-06-22 Philippe Marliere Method for producing an alkene comprising the step of converting an alcohol by an enzymatic dehydration step
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US20120040421A1 (en) 2010-03-10 2012-02-16 Lanza Tech New Zealand Limited Acid production by fermentation
WO2012024522A2 (en) 2010-08-19 2012-02-23 Lanzatech New Zealand Limited A process for producing chemicals using microbial fermentation of substrates comprising carbon monoxide
EP2609206A4 (en) 2010-08-26 2014-07-09 Lanzatech New Zealand Ltd PROCESS FOR THE PRODUCTION OF ETHANOL AND ETHYLENE BY FERMENTATION
US20110236941A1 (en) 2010-10-22 2011-09-29 Lanzatech New Zealand Limited Recombinant microorganism and methods of production thereof
US8271519B2 (en) 2010-11-01 2012-09-18 Sas Institute Inc. Systems and methods for fast remote data access from a spreadsheet
US9365868B2 (en) 2011-02-25 2016-06-14 Lanzatech New Zealand Limited Fermentation process for producing isopropanol using a recombinant microorganism
MY168208A (en) * 2011-02-25 2018-10-15 Lanzatech New Zealand Ltd Recombinant microorganisms and uses therefor
ES2788510T3 (es) 2011-09-08 2020-10-21 Lanzatech New Zealand Ltd Proceso de fermentación
ES2583203T3 (es) 2012-01-31 2016-09-19 Lanzatech New Zealand Limited Microorganismos recombinantes y métodos de uso de los mismos
CN104508136A (zh) 2012-05-30 2015-04-08 新西兰郎泽科技公司 重组微生物及其用途
US20130323820A1 (en) 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
JP6381525B2 (ja) 2012-06-08 2018-08-29 ランザテク・ニュージーランド・リミテッド 組換え微生物およびその使用
US9347076B2 (en) 2012-06-21 2016-05-24 Lanzatech New Zealand Limited Recombinant microorganisms that make biodiesel
CA2882276C (en) 2012-08-28 2016-11-01 Lanzatech New Zealand Limited Recombinant microorganisms expressing a stereospecific diol dehydratase enzyme
US8787096B1 (en) 2013-01-16 2014-07-22 Qualcomm Incorporated N-well switching circuit
EP2813575A1 (de) * 2013-06-14 2014-12-17 Evonik Industries AG Verfahren zur Herstellung von organischen Verbindungen aus Knallgas und CO2 über Acetoacetyl-CoA als Zwischenprodukt
WO2015084633A1 (en) * 2013-12-03 2015-06-11 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
US20150152445A1 (en) 2013-12-03 2015-06-04 Lanzatech New Zealand Limited Microorganisms and methods for the production of ketones
AU2014375396A1 (en) 2013-12-31 2016-06-09 Global Bioenergies 3-hydroxyisovalerate (HIV) synthase variants
US20170283809A1 (en) 2014-09-03 2017-10-05 Global Bioenergies Recombinant microorganism producing alkenes from acetyl-coa
EP3362567A4 (en) * 2015-10-13 2019-03-27 Lanzatech New Zealand Limited GENETICALLY MODIFIED BACTERIUM COMPRISING AN ENERGY-EFFICIENT FERMENTATION PATHWAY

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