MX2021003330A - Bacteria dise?ada por ingenieria genetica que comprende una trayectoria de fermentacion que genera energia. - Google Patents

Bacteria dise?ada por ingenieria genetica que comprende una trayectoria de fermentacion que genera energia.

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Publication number
MX2021003330A
MX2021003330A MX2021003330A MX2021003330A MX2021003330A MX 2021003330 A MX2021003330 A MX 2021003330A MX 2021003330 A MX2021003330 A MX 2021003330A MX 2021003330 A MX2021003330 A MX 2021003330A MX 2021003330 A MX2021003330 A MX 2021003330A
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energy
genetically engineered
engineered bacterium
fermentation pathway
buk
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MX2021003330A
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English (en)
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James Bruce Yarnton Haycock Behrendorff
Alexander Paul Mueller
Michael Kopke
Ryan Edward Hill
Rasmus Overgaard Jensen
Darmawi Juminaga
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Lanzatech Nz Inc
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Publication of MX2021003330A publication Critical patent/MX2021003330A/es

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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract

La presente invención se refiere a una bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía y métodos relacionados a esta. En particular, la invención proporciona una bacteria que comprende una fosfato butiriltransferasa (Ptb) y una butirato cinasa (Buk) (Ptb-Buk) que actúa en sustratos no nativos para producir una amplia variedad de productos e intermediarios. En ciertas modalidades, la invención se refiere a la introducción de Ptb-Buk en un microorganismo que se fija a C1 capaz de producir productos a partir de un sustrato gaseoso.
MX2021003330A 2015-10-13 2018-04-13 Bacteria dise?ada por ingenieria genetica que comprende una trayectoria de fermentacion que genera energia. MX2021003330A (es)

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US201562240850P 2015-10-13 2015-10-13

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MX2021003330A true MX2021003330A (es) 2021-05-14

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ID=58499646

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Application Number Title Priority Date Filing Date
MX2023003058A MX2023003058A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2018004642A MX2018004642A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2022003568A MX2022003568A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2021003330A MX2021003330A (es) 2015-10-13 2018-04-13 Bacteria dise?ada por ingenieria genetica que comprende una trayectoria de fermentacion que genera energia.

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MX2023003058A MX2023003058A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2018004642A MX2018004642A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2022003568A MX2022003568A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.

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US (3) US9738875B2 (es)
EP (2) EP3901267A1 (es)
JP (2) JP6905518B2 (es)
KR (2) KR20210037002A (es)
CN (2) CN108884467A (es)
AU (2) AU2016339989B2 (es)
BR (1) BR112018007338A2 (es)
CA (6) CA3001596C (es)
EA (2) EA201890952A1 (es)
MX (4) MX2023003058A (es)
MY (1) MY194651A (es)
WO (1) WO2017066498A1 (es)
ZA (5) ZA201802346B (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA40644A (fr) * 2014-09-17 2016-03-24 Global Bioenergies Procédés pour produire de l'acide 3-hydroxy-3-méthylbutyrique
WO2016210384A2 (en) 2015-06-25 2016-12-29 Synlogic, Inc. Bacteria engineered to treat metabolic diseases
MY194651A (en) * 2015-10-13 2022-12-09 Lanzatech Nz Inc Genetically engineered bacterium for the production of isobutylene
GB201603915D0 (en) * 2016-03-07 2016-04-20 Chain Biotechnology Ltd Method and microbes for the production of chiral compounds
EP3464559A4 (en) 2016-05-14 2020-02-12 Lanzatech, Inc. MODIFIED ALDEHYDE / FERREDOXIN OXYDOREDUCTASE MICROORGANISM AND RELATED METHODS
WO2018098349A1 (en) 2016-11-22 2018-05-31 The Penn State Research Foundation Devices and methods for generating electrical current from methane
CN107177609B (zh) * 2017-05-15 2020-12-11 大连理工大学 一种fruB基因过表达的重组梭菌、其构建方法及应用
CN107083406B (zh) * 2017-05-27 2021-02-02 浙江华睿生物技术有限公司 (r)-3-羟基丁酸的生产方法
US11634733B2 (en) * 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
PT3679149T (pt) 2017-09-08 2022-09-05 Lanzatech Inc Processos para produção de metabolitos usando substratos contendo c1 ricos em hidrogénio
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
EA202090833A1 (ru) * 2017-09-28 2020-07-16 Ланцатек, Инк. Нокауты в генах микроорганизмов вуда-льюнгдаля
EP3719121A4 (en) * 2017-11-30 2021-12-15 Toray Industries, Inc. GENE-MODIFIED MICROORGANISM FOR THE PRODUCTION OF 3-HYDROXYADIPIC ACID, -HYDROMUCONIC ACID AND / OR ADIPIC ACID AND THE MANUFACTURING METHOD FOR THESE CHEMICAL PRODUCTS
AU2018393075B2 (en) 2017-12-19 2024-03-21 Lanzatech, Inc. Microorganisms and methods for the biological production of ethylene glycol
EP3743520A4 (en) * 2018-01-23 2021-11-10 Lanzatech, Inc. TWO-STAGE FERMENTATION PROCESS FOR MANUFACTURING A PRODUCT
US11661613B2 (en) 2018-02-01 2023-05-30 Inv Nylon Chemicals Americas, Llc Methods and materials for the biosynthesis of hydroxy fatty acid anions and/or derivatives thereof and/or compounds related thereto
CN111683731B (zh) 2018-02-12 2022-09-02 朗泽科技有限公司 用于提高碳转化效率的工艺
ES2960999T3 (es) 2018-04-20 2024-03-07 Lanzatech Inc Proceso de fermentación para producir etanol
CN109251940B (zh) * 2018-10-30 2020-10-16 浙江华睿生物技术有限公司 一种产β-羟基-β-甲基丁酸工程菌的构建方法
SG11202105051SA (en) 2018-11-19 2021-06-29 Lanzatech Inc Integration of fermentation and gasification
KR20210100749A (ko) 2019-02-08 2021-08-17 란자테크, 인크. 유사한 비등점 생성물의 회수 방법
US20220145336A1 (en) 2019-03-20 2022-05-12 Global Bioenergies Means and methods for producing isobutene from acetyl-coa
FR3096373A1 (fr) * 2019-05-24 2020-11-27 IFP Energies Nouvelles Outil genetique optimisé pour modifier les bacteries
KR20210134988A (ko) 2019-07-11 2021-11-11 란자테크, 인크. 가스 이용률을 최적화하는 방법
US20220258100A1 (en) * 2019-07-16 2022-08-18 San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation Products of manufacture and methods for methane capturing using biofiltration
CN112280723B (zh) * 2019-07-23 2022-08-19 清华大学 联产1,3-丙二醇和1,3-丁二醇的重组菌及其应用
CN112280722B (zh) * 2019-07-23 2022-03-08 清华大学 用于生产光学纯1,3-丁二醇的重组菌及其应用
JP7376041B2 (ja) * 2019-09-11 2023-11-08 公益財団法人地球環境産業技術研究機構 形質転換体及びそれを用いる1,3-ブタンジオールの製造方法
CN111089914A (zh) * 2019-11-07 2020-05-01 河北首朗新能源科技有限公司 微生物发酵生产乙醇中代谢物的高效液相检测方法
CN114846050A (zh) * 2019-12-23 2022-08-02 希欧生物清洁有限公司 新型生物塑料
JP7475598B2 (ja) 2020-03-04 2024-04-30 大阪瓦斯株式会社 1,3-ブタンジオールの製造方法
CN111220762A (zh) * 2020-03-24 2020-06-02 河北首朗新能源科技有限公司 一种乙醇梭菌蛋白中有机物的含量的检测方法及应用
US20210340579A1 (en) * 2020-04-29 2021-11-04 Lanzatech, Inc. FERMENTATIVE PRODUCTION OF ß-KETOADIPATE FROM GASEOUS SUBSTRATES
BR112022024652B1 (pt) 2020-06-06 2024-01-16 Lanzatech, Inc Micro-organismo geneticamente modificado, e, método para a produção de um produto
KR20230042416A (ko) * 2020-09-25 2023-03-28 란자테크, 인크. 재조합 미생물 및 이의 용도
KR102443037B1 (ko) 2020-10-23 2022-09-14 한국과학기술연구원 에탄올을 포함하는 합성 가스로부터 2,3-부탄디올 제조용 배지 조성물 및 이를 이용한 2,3-부탄디올 생산 방법
CN116348603B (zh) 2021-02-08 2024-07-02 朗泽科技有限公司 重组微生物及其用途
CN115369048B (zh) * 2021-05-17 2023-10-20 华东理工大学 一种产玉米黄质的解脂耶氏酵母基因工程菌及其构建方法和应用
TW202307202A (zh) 2021-08-06 2023-02-16 美商朗澤科技有限公司 用於改良乙二醇之生物產生的微生物及方法
EP4279586A4 (en) 2022-04-06 2024-02-28 Shenzhen Bluepha Biosciences Co., Ltd. MODIFIED MICROORGANISM EXPRESSING AN ACETOACETYL REDUCTASE COENZYME VARIANT AND METHOD FOR INCREASING PHA YIELD
CN116121218B (zh) * 2022-04-06 2023-11-24 深圳蓝晶生物科技有限公司 表达乙酰乙酰辅酶a还原酶变体的工程化微生物及提高pha产量的方法

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593886A (en) 1992-10-30 1997-01-14 Gaddy; James L. Clostridium stain which produces acetic acid from waste gases
UA72220C2 (uk) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання
CN1217001C (zh) * 2002-01-04 2005-08-31 清华大学 一种生产d-(-)-3-羟基丁酸的方法
ZA200802682B (en) * 2005-09-29 2009-09-30 Du Pont Fermentive production of four carbon alcohols
NZ546496A (en) 2006-04-07 2008-09-26 Lanzatech New Zealand Ltd Gas treatment process
US7704723B2 (en) 2006-08-31 2010-04-27 The Board Of Regents For Oklahoma State University Isolation and characterization of novel clostridial species
NZ553984A (en) 2007-03-19 2009-07-31 Lanzatech New Zealand Ltd Alcohol production process
KR101114918B1 (ko) * 2007-08-09 2012-02-15 주식회사 엘지화학 재조합 미생물을 이용한 광학활성(s)-3-하이드록시부탄산 및(s)-3-하이드록시부티레이트 에스테르의 제조방법
KR101042242B1 (ko) * 2007-09-07 2011-06-17 한국과학기술원 1,4-부탄디올 생성능을 가지는 변이체 및 이를 이용한1,4-부탄디올의 제조방법
CN101918538B (zh) 2007-11-13 2013-01-30 兰扎泰克新西兰有限公司 一种厌氧菌及其用途
SI2265709T1 (en) * 2008-03-27 2018-03-30 Genomatica, Inc. MICROORGANISMS FOR PREPARATION OF ADYPIC ACID AND OTHER COMPOUNDS
NZ589632A (en) 2008-06-09 2013-03-28 Lanzatech New Zealand Ltd Production of butanediol by anaerobic microbial fermentation
EP2304040B1 (fr) 2008-07-04 2017-09-06 Scientist of Fortune S.A. Production d'alcenes par decarboxylation enzymatique d'acides 3-hydroxy-alcanoïques
WO2010022763A1 (en) * 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
MY161071A (en) * 2008-12-30 2017-04-14 Danisco Us Inc Methods of producing isoprene and a co-product
KR20120068021A (ko) * 2009-09-09 2012-06-26 게노마티카 인코포레이티드 아이소프로판올과 1차 알콜, 다이올 및 산과의 공동 생산을 위한 미생물 및 방법
EP2295593A1 (en) 2009-09-15 2011-03-16 Philippe Marliere Method for the enymatic production of 3-hydroxy-3-methylbutyric acid from acetone and acetyl-CoA
US8268607B2 (en) * 2009-12-10 2012-09-18 Genomatica, Inc. Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
EP2336341A1 (en) 2009-12-21 2011-06-22 Philippe Marliere Method for producing an alkene comprising the step of converting an alcohol by an enzymatic dehydration step
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
WO2011112103A1 (en) 2010-03-10 2011-09-15 Lanzatech New Zealand Limited Acid production by fermentation
WO2012024522A2 (en) 2010-08-19 2012-02-23 Lanzatech New Zealand Limited A process for producing chemicals using microbial fermentation of substrates comprising carbon monoxide
EP2609206A4 (en) 2010-08-26 2014-07-09 Lanzatech New Zealand Ltd PROCESS FOR THE PRODUCTION OF ETHANOL AND ETHYLENE BY FERMENTATION
US20110236941A1 (en) 2010-10-22 2011-09-29 Lanzatech New Zealand Limited Recombinant microorganism and methods of production thereof
US8271519B2 (en) 2010-11-01 2012-09-18 Sas Institute Inc. Systems and methods for fast remote data access from a spreadsheet
KR102121886B1 (ko) 2011-02-25 2020-06-15 란자테크 뉴질랜드 리미티드 재조합 미생물 및 이의 용도
US9365868B2 (en) * 2011-02-25 2016-06-14 Lanzatech New Zealand Limited Fermentation process for producing isopropanol using a recombinant microorganism
PL2753700T3 (pl) 2011-09-08 2020-07-27 Lanzatech New Zealand Limited Sposób fermentacji
CA2862790C (en) 2012-01-31 2016-09-27 Lanzatech New Zealand Limited A recombinant carboxydotrophic acetogenic microorganism and uses thereof in microbial fermentation
US9994878B2 (en) 2012-05-30 2018-06-12 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
US20130323820A1 (en) * 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
WO2013185123A1 (en) 2012-06-08 2013-12-12 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
US9347076B2 (en) 2012-06-21 2016-05-24 Lanzatech New Zealand Limited Recombinant microorganisms that make biodiesel
CN105051179B (zh) 2012-08-28 2018-06-15 朗泽科技新西兰有限公司 重组微生物和其用途
US8787096B1 (en) 2013-01-16 2014-07-22 Qualcomm Incorporated N-well switching circuit
EP2813575A1 (de) * 2013-06-14 2014-12-17 Evonik Industries AG Verfahren zur Herstellung von organischen Verbindungen aus Knallgas und CO2 über Acetoacetyl-CoA als Zwischenprodukt
PL3077501T3 (pl) * 2013-12-03 2022-01-31 Genomatica, Inc. Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa
JP2016538869A (ja) 2013-12-03 2016-12-15 ランザテク・ニュージーランド・リミテッド ケトンの生成のための微生物及び方法
US10364418B2 (en) * 2013-12-31 2019-07-30 Global Bioenergies 3-hydroxyisovalerate (HIV) synthase variants
JP2017525380A (ja) 2014-09-03 2017-09-07 グローバル・バイオエナジーズ アセチルCoAからアルケンを生成する組換え微生物
MY194651A (en) * 2015-10-13 2022-12-09 Lanzatech Nz Inc Genetically engineered bacterium for the production of isobutylene

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