MX2021009611A - Reduccion de los niveles o la actividad de las celulas t reguladoras sistemicas para el tratamiento de enfermedad y lesion del sistema nervioso central (snc). - Google Patents
Reduccion de los niveles o la actividad de las celulas t reguladoras sistemicas para el tratamiento de enfermedad y lesion del sistema nervioso central (snc).Info
- Publication number
- MX2021009611A MX2021009611A MX2021009611A MX2021009611A MX2021009611A MX 2021009611 A MX2021009611 A MX 2021009611A MX 2021009611 A MX2021009611 A MX 2021009611A MX 2021009611 A MX2021009611 A MX 2021009611A MX 2021009611 A MX2021009611 A MX 2021009611A
- Authority
- MX
- Mexico
- Prior art keywords
- disease
- cns
- injury
- treatment
- activity
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 208000027418 Wounds and injury Diseases 0.000 title abstract 2
- 230000006378 damage Effects 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000014674 injury Diseases 0.000 title abstract 2
- 230000009885 systemic effect Effects 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title 1
- 210000003289 regulatory T cell Anatomy 0.000 title 1
- 208000007400 Relapsing-Remitting Multiple Sclerosis Diseases 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 206010062016 Immunosuppression Diseases 0.000 abstract 1
- 208000036110 Neuroinflammatory disease Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000001363 autoimmune Effects 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
Classifications
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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Abstract
Se provee una composición farmacéutica que comprende un agente activo que causa la reducción del nivel de inmunosupresión sistémica en un individuo para su uso en el tratamiento de una enfermedad, trastorno, condición o lesión del sistema nervioso central que no incluye la enfermedad neuroinflamatoria autoinmune, esclerosis múltiple recurrente-remitente (RRMS); la composición farmacéutica es para administración mediante un régimen de dosificación que comprende por lo menos dos cursos de terapia, cada curso de terapia comprendiendo en secuencia una sesión de tratamiento seguida de una sesión de intervalo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461951783P | 2014-03-12 | 2014-03-12 | |
US201462030164P | 2014-07-29 | 2014-07-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021009611A true MX2021009611A (es) | 2021-09-08 |
Family
ID=53488381
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016011832A MX2016011832A (es) | 2014-03-12 | 2015-03-12 | Reduccion de los niveles o la actividad de las células t reguladoras sistémicas para el tratamiento de enfermedad y lesión del sistema nervioso central (snc). |
MX2018000466A MX2018000466A (es) | 2014-03-12 | 2016-07-13 | Reducción de niveles o de actividad de células t regulatorias sistémicas para el tratamiento de enfermedad y lesión del sistema nervioso central (snc). |
MX2021009611A MX2021009611A (es) | 2014-03-12 | 2016-09-12 | Reduccion de los niveles o la actividad de las celulas t reguladoras sistemicas para el tratamiento de enfermedad y lesion del sistema nervioso central (snc). |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016011832A MX2016011832A (es) | 2014-03-12 | 2015-03-12 | Reduccion de los niveles o la actividad de las células t reguladoras sistémicas para el tratamiento de enfermedad y lesión del sistema nervioso central (snc). |
MX2018000466A MX2018000466A (es) | 2014-03-12 | 2016-07-13 | Reducción de niveles o de actividad de células t regulatorias sistémicas para el tratamiento de enfermedad y lesión del sistema nervioso central (snc). |
Country Status (13)
Country | Link |
---|---|
US (16) | US10144778B2 (es) |
EP (1) | EP3116542A2 (es) |
JP (6) | JP6903432B2 (es) |
KR (4) | KR102248804B1 (es) |
CN (2) | CN114081946A (es) |
AU (5) | AU2015228372B2 (es) |
BR (2) | BR112016020919A2 (es) |
CA (3) | CA2942245C (es) |
IL (2) | IL256792B2 (es) |
MX (3) | MX2016011832A (es) |
NZ (2) | NZ747418A (es) |
RU (2) | RU2690670C2 (es) |
WO (2) | WO2015136541A2 (es) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108997498A (zh) | 2008-12-09 | 2018-12-14 | 霍夫曼-拉罗奇有限公司 | 抗-pd-l1抗体及它们用于增强t细胞功能的用途 |
PL3081576T3 (pl) | 2013-12-12 | 2020-03-31 | Shanghai Hengrui Pharmaceutical Co., Ltd. | Przeciwciało anty pd-1, jego fragment wiążący antygen i ich zastosowanie medyczne |
GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
US9394365B1 (en) * | 2014-03-12 | 2016-07-19 | Yeda Research And Development Co., Ltd | Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease |
NZ747418A (en) | 2014-03-12 | 2023-05-26 | Yeda Res & Dev | Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns |
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