MX2019001469A - Tratamiento del cáncer usando un receptor de antígeno quimérico en combinación con un inhibidor de una molécula de macrófago pro- m2. - Google Patents

Tratamiento del cáncer usando un receptor de antígeno quimérico en combinación con un inhibidor de una molécula de macrófago pro- m2.

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Publication number
MX2019001469A
MX2019001469A MX2019001469A MX2019001469A MX2019001469A MX 2019001469 A MX2019001469 A MX 2019001469A MX 2019001469 A MX2019001469 A MX 2019001469A MX 2019001469 A MX2019001469 A MX 2019001469A MX 2019001469 A MX2019001469 A MX 2019001469A
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MX
Mexico
Prior art keywords
pro
inhibitor
combination
cancer
treatment
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Application number
MX2019001469A
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English (en)
Inventor
Gill Saar
Klichinsky Michael
Ruella Marco
Original Assignee
Novartis Ag
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Publication of MX2019001469A publication Critical patent/MX2019001469A/es

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Abstract

La invención proporciona invenciones y métodos para el tratamiento de enfermedades asociadas con la expresión de un antígeno, por ejemplo, un antígeno de tumo sólido o antígeno expresado en un tumor asociado con TAM y/o MDSC, mediante la administración de un linfocito T recombinante que comprende un CAR que se une a dicho antígeno, como se describe en el presente documento, en combinación con un inhibidor de una molécula de macrófago pro-M2, por ejemplo, descrita en el presente documento. La invención también proporciona kits y composiciones descritas en el presente documento.
MX2019001469A 2016-08-01 2017-08-01 Tratamiento del cáncer usando un receptor de antígeno quimérico en combinación con un inhibidor de una molécula de macrófago pro- m2. MX2019001469A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662369589P 2016-08-01 2016-08-01
PCT/US2017/044909 WO2018026819A2 (en) 2016-08-01 2017-08-01 Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule

Publications (1)

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MX2019001469A true MX2019001469A (es) 2019-10-02

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MX2019001469A MX2019001469A (es) 2016-08-01 2017-08-01 Tratamiento del cáncer usando un receptor de antígeno quimérico en combinación con un inhibidor de una molécula de macrófago pro- m2.

Country Status (13)

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US (1) US20190161542A1 (es)
EP (1) EP3490590A2 (es)
JP (2) JP2019527696A (es)
KR (1) KR20190036551A (es)
CN (1) CN110267677A (es)
AU (1) AU2017306267A1 (es)
BR (1) BR112019002035A2 (es)
CA (1) CA3032581A1 (es)
IL (1) IL264588A (es)
MX (1) MX2019001469A (es)
RU (1) RU2019105693A (es)
SG (1) SG11201900885VA (es)
WO (1) WO2018026819A2 (es)

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WO2018026819A2 (en) 2018-02-08
AU2017306267A1 (en) 2019-02-14
SG11201900885VA (en) 2019-02-27
CA3032581A1 (en) 2018-02-08
KR20190036551A (ko) 2019-04-04
US20190161542A1 (en) 2019-05-30
EP3490590A2 (en) 2019-06-05
JP2019527696A (ja) 2019-10-03
JP2022062040A (ja) 2022-04-19
RU2019105693A3 (es) 2021-04-26
WO2018026819A3 (en) 2018-03-08
CN110267677A (zh) 2019-09-20
BR112019002035A2 (pt) 2019-05-14
RU2019105693A (ru) 2020-09-01

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