|
US8124759B2
(en)
|
2007-05-09 |
2012-02-28 |
Abbott Laboratories |
Inhibitors of protein kinases
|
|
EP2155758B1
(en)
*
|
2007-05-10 |
2012-08-22 |
Biocryst Pharmaceuticals, Inc. |
Tetrahydrofuro[3,4-d]dioxolane compounds for use in the treatment of viral infections and cancer
|
|
TW200942243A
(en)
|
2008-03-05 |
2009-10-16 |
Biocryst Pharm Inc |
Antiviral therapeutic agents
|
|
US20090247750A1
(en)
*
|
2008-03-28 |
2009-10-01 |
Biocryst Pharmaceuticals, Inc. |
Process for preparing nucleoside analogs
|
|
CN102046626A
(zh)
|
2008-04-23 |
2011-05-04 |
吉里德科学公司 |
用于抗病毒治疗的carba-核苷类似物
|
|
EP2313102A2
(en)
|
2008-07-03 |
2011-04-27 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
|
AU2010213873B2
(en)
|
2009-02-10 |
2015-07-09 |
Gilead Sciences, Inc. |
Carba-nucleoside analogs for antiviral treatment
|
|
DK2480559T3
(da)
|
2009-09-21 |
2013-08-05 |
Gilead Sciences Inc |
Fremgangsmåder og mellemprodukter til fremstillingen af 1'-cyano-carbanukleosid-analoger
|
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
KR20180006499A
(ko)
*
|
2009-09-21 |
2018-01-17 |
길리애드 사이언시즈, 인코포레이티드 |
항바이러스 치료용 2'―플루오로 치환된 카바-뉴클레오사이드 유사체
|
|
US8455451B2
(en)
|
2009-09-21 |
2013-06-04 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
EP2552922A1
(en)
|
2010-03-31 |
2013-02-06 |
Bristol-Myers Squibb Company |
Substituted pyrrolotriazines as protein kinase inhibitors
|
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
|
PH12013500033A1
(en)
|
2010-07-19 |
2017-07-26 |
Gilead Sciences Inc |
Methods for the preparation of diasteromerically pure phosphoramidate prodrugs
|
|
MA34470B1
(fr)
|
2010-07-22 |
2013-08-01 |
Gilead Sciences Inc |
Procédés et composés pour traiter des infections à virus paramyxoviridae
|
|
TW201305185A
(zh)
*
|
2010-09-13 |
2013-02-01 |
Gilead Sciences Inc |
用於抗病毒治療之2’-氟取代之碳-核苷類似物
|
|
AU2011306066B2
(en)
|
2010-09-20 |
2015-01-29 |
Gilead Sciences, Inc. |
2' -fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
AU2011305652B2
(en)
|
2010-09-22 |
2016-10-20 |
Janssen Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
EP2697241B1
(en)
|
2011-04-13 |
2019-06-12 |
Gilead Sciences, Inc. |
1'-substituted pyrimidine n-nucleoside analogs for antiviral treatment
|
|
EA023775B1
(ru)
|
2011-07-01 |
2016-07-29 |
Байер Интеллектуэль Проперти Гмбх |
Гидроксиметиларилзамещенные пирролотриазины в качестве ингибиторов alk1
|
|
TW201329096A
(zh)
|
2011-09-12 |
2013-07-16 |
Idenix Pharmaceuticals Inc |
經取代羰氧基甲基磷酸醯胺化合物及用於治療病毒感染之藥學組成物
|
|
CA2752008A1
(en)
|
2011-09-13 |
2013-03-13 |
Universite De Montreal |
Combination therapy using ribavirin as elf4e inhibitor
|
|
SI2794627T1
(sl)
|
2011-12-22 |
2019-02-28 |
Alios Biopharma, Inc. |
Substituirani nukleozidi, nukleotidi in njihovi analogi
|
|
JP6242378B2
(ja)
|
2012-03-13 |
2017-12-06 |
ギリアード サイエンシーズ, インコーポレイテッド |
抗ウイルス処置のための2’−置換カルバヌクレオシド類似体
|
|
US9441007B2
(en)
|
2012-03-21 |
2016-09-13 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
USRE48171E1
(en)
|
2012-03-21 |
2020-08-25 |
Janssen Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
AR090699A1
(es)
|
2012-04-18 |
2014-12-03 |
Biocryst Pharm Inc |
Compuestos inhibidores de la actividad de la arn polimerasa viral
|
|
HUE042374T2
(hu)
|
2012-06-13 |
2019-06-28 |
Incyte Holdings Corp |
Szubsztituált triciklusos vegyületek mint FGFR inhibitorok
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
HK1212235A1
(en)
*
|
2012-11-16 |
2016-06-10 |
Biocryst Pharmaceuticals, Inc. |
Antiviral azasugar-containing nucleosides
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
KR102469849B1
(ko)
|
2013-04-19 |
2022-11-23 |
인사이트 홀딩스 코포레이션 |
Fgfr 저해제로서 이환식 헤테로사이클
|
|
JP6562908B2
(ja)
|
2013-10-11 |
2019-08-21 |
ヤンセン バイオファーマ インク. |
置換ヌクレオシド、置換ヌクレオチドおよびその類似体
|
|
UA119050C2
(uk)
|
2013-11-11 |
2019-04-25 |
Ґілеад Саєнсиз, Інк. |
ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
|
|
WO2015143712A1
(en)
|
2014-03-28 |
2015-10-01 |
Merck Sharp & Dohme Corp. |
4'-substituted nucleoside reverse transcriptase inhibitors
|
|
TWI678369B
(zh)
|
2014-07-28 |
2019-12-01 |
美商基利科學股份有限公司 |
用於治療呼吸道合胞病毒感染之噻吩並[3,2-d]嘧啶、呋喃並[3,2-d]嘧啶及吡咯並[3,2-d]嘧啶化合物類
|
|
TWI673283B
(zh)
|
2014-08-21 |
2019-10-01 |
美商基利科學股份有限公司 |
2’-氯胺基嘧啶酮及嘧啶二酮核苷類
|
|
WO2016064957A1
(en)
|
2014-10-22 |
2016-04-28 |
Bristol-Myers Squibb Company |
Bicyclic heteroaryl amine compounds as pi3k inhibitors
|
|
US10023576B2
(en)
|
2014-10-22 |
2018-07-17 |
Bristol-Myers Squibb Company |
Heteroaryl substituted pyrrolotriazine amine compounds as PI3K inhibitors
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
TWI767201B
(zh)
|
2014-10-29 |
2022-06-11 |
美商基利科學股份有限公司 |
絲狀病毒科病毒感染之治療
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
AU2016219822B2
(en)
|
2015-02-20 |
2020-07-09 |
Incyte Holdings Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
CN107427530B
(zh)
|
2015-03-06 |
2020-09-08 |
阿堤亚制药公司 |
用于HCV治疗的β-D-2’-脱氧-2’α-氟-2’-β-C-取代的-2-改性的-N6-取代的嘌呤核苷酸
|
|
CN104876935B
(zh)
*
|
2015-05-18 |
2017-04-19 |
南方医科大学 |
2‑氨基吡咯并[1,2‑f][1,2,4]三嗪类化合物、合成方法及应用
|
|
MX394858B
(es)
|
2015-09-16 |
2025-03-24 |
Gilead Sciences Inc |
Compuestos de formula i para usarse en el tratamiento de infecciones por virus arenaviridae y coronaviridae
|
|
RU2720811C2
(ru)
|
2015-09-23 |
2020-05-13 |
Мерк Шарп И Доум Лимитед |
4'-замещенные нуклеозидные ингибиторы обратной транскриптазы и их получение
|
|
CN108883167A
(zh)
|
2016-03-09 |
2018-11-23 |
加州大学洛杉矶分校港口医学中心生物医学研究所 |
用于预防和治疗外阴阴道念珠菌病的方法和药剂盒
|
|
AU2017231824B2
(en)
|
2016-03-09 |
2021-07-01 |
Alios Biopharma, Inc. |
Acyclic antivirals
|
|
PT3436461T
(pt)
|
2016-03-28 |
2024-01-23 |
Incyte Corp |
Compostos de pirrolotriazina como inibidores de tam
|
|
WO2018013937A1
(en)
|
2016-07-14 |
2018-01-18 |
Atea Pharmaceuticals, Inc. |
Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
|
AU2017324939B2
(en)
|
2016-09-07 |
2021-10-14 |
Atea Pharmaceuticals, Inc. |
2'-substituted-N6-substituted purine nucleotides for RNA virus treatment
|
|
CA3040540A1
(en)
|
2016-11-10 |
2018-05-17 |
Oyagen, Inc. |
Methods of treating and inhibiting ebola virus infection
|
|
US10519186B2
(en)
|
2017-02-01 |
2019-12-31 |
Atea Pharmaceuticals, Inc. |
Nucleotide hemi-sulfate salt for the treatment of hepatitis C virus
|
|
CA3056072C
(en)
|
2017-03-14 |
2022-08-23 |
Gilead Sciences, Inc. |
Methods of treating feline coronavirus infections
|
|
KR20190141747A
(ko)
|
2017-05-01 |
2019-12-24 |
길리애드 사이언시즈, 인코포레이티드 |
(S)-2-에틸부틸 2-(((S)-(((2R,3S,4R,5R)-5-(4-아미노피롤로[2,1-f] [1,2,4]트리아진-7-일)-5-시아노-3,4-디히드록시테트라히드로푸란-2-일)메톡시)(페녹시) 포스포릴)아미노)프로파노에이트의 결정질 형태
|
|
CN107056775A
(zh)
*
|
2017-05-24 |
2017-08-18 |
佛山科学技术学院 |
丙型肝炎病毒ns5b聚合酶抑制剂
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
EP4512475A3
(en)
|
2017-07-11 |
2025-05-14 |
Gilead Sciences, Inc. |
Compositions comprising an rna polymerase inhibitor and cyclodextrin for treating viral infections
|
|
US11040975B2
(en)
|
2017-12-08 |
2021-06-22 |
Merck Sharp & Dohme Corp. |
Carbocyclic nucleoside reverse transcriptase inhibitors
|
|
KR20200140865A
(ko)
|
2018-04-10 |
2020-12-16 |
아테아 파마슈티컬즈, 인크. |
간경변증을 갖는 hcv 감염 환자의 치료
|
|
EP4309737A3
(en)
|
2018-05-04 |
2024-03-27 |
Incyte Corporation |
Solid forms of an fgfr inhibitor and processes for preparing the same
|
|
EP3788046B1
(en)
|
2018-05-04 |
2025-12-10 |
Incyte Corporation |
Salts of an fgfr inhibitor
|
|
CA3122410A1
(en)
|
2018-12-12 |
2020-06-18 |
Janssen Biopharma, Inc. |
Cyclopentyl nucleoside analogs as anti-virals
|
|
US11628162B2
(en)
|
2019-03-08 |
2023-04-18 |
Incyte Corporation |
Methods of treating cancer with an FGFR inhibitor
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
US12122767B2
(en)
|
2019-10-01 |
2024-10-22 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021076602A1
(en)
|
2019-10-14 |
2021-04-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2021076728A1
(en)
|
2019-10-16 |
2021-04-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
KR20220131900A
(ko)
|
2019-12-04 |
2022-09-29 |
인사이트 코포레이션 |
Fgfr 억제제의 유도체
|
|
JP7720840B2
(ja)
|
2019-12-04 |
2025-08-08 |
インサイト・コーポレイション |
Fgfr阻害剤としての三環式複素環
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
AU2021214911A1
(en)
|
2020-01-27 |
2022-07-21 |
Gilead Sciences, Inc. |
Methods for treating SARS CoV-2 infections
|
|
US11738025B2
(en)
|
2020-02-04 |
2023-08-29 |
Oyagen, Inc. |
Method for treating coronavirus infections
|
|
CN113214262B
(zh)
*
|
2020-02-05 |
2023-07-07 |
华创合成制药股份有限公司 |
一种含有胍基的化合物及其制备方法和用途
|
|
TWI775313B
(zh)
|
2020-02-18 |
2022-08-21 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
AU2021224588B2
(en)
|
2020-02-18 |
2024-07-18 |
Gilead Sciences, Inc. |
Antiviral compounds
|
|
TWI791193B
(zh)
|
2020-02-18 |
2023-02-01 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
TWI883391B
(zh)
|
2020-02-18 |
2025-05-11 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
US10874687B1
(en)
|
2020-02-27 |
2020-12-29 |
Atea Pharmaceuticals, Inc. |
Highly active compounds against COVID-19
|
|
KR20220153619A
(ko)
|
2020-03-12 |
2022-11-18 |
길리애드 사이언시즈, 인코포레이티드 |
1'-시아노 뉴클레오사이드의 제조 방법
|
|
WO2021207049A1
(en)
|
2020-04-06 |
2021-10-14 |
Gilead Sciences, Inc. |
Inhalation formulations of 1'-cyano substituted carbanucleoside analogs
|
|
JP7664287B2
(ja)
|
2020-05-29 |
2025-04-17 |
ギリアード サイエンシーズ, インコーポレイテッド |
レムデシビル治療方法
|
|
AU2021296841B2
(en)
|
2020-06-24 |
2025-01-23 |
Gilead Sciences, Inc. |
1'-cyano nucleoside analogs and uses thereof
|
|
WO2022011554A1
(zh)
*
|
2020-07-14 |
2022-01-20 |
四川大学 |
3-去氧-2-酮糖酸含氮衍生物及其制备方法和用途
|
|
KR20250111239A
(ko)
|
2020-08-27 |
2025-07-22 |
길리애드 사이언시즈, 인코포레이티드 |
바이러스 감염 치료를 위한 화합물 및 방법
|
|
CA3215903A1
(en)
|
2021-04-12 |
2022-10-20 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
|
KR20230170745A
(ko)
|
2021-04-16 |
2023-12-19 |
길리애드 사이언시즈, 인코포레이티드 |
아미드를 사용한 카르바뉴클레오시드를 제조하는 방법
|
|
WO2022261159A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
EP4352059A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
CN117500494A
(zh)
|
2021-06-17 |
2024-02-02 |
阿堤亚制药公司 |
有利的抗hcv联合疗法
|
|
US12116380B2
(en)
|
2021-08-18 |
2024-10-15 |
Gilead Sciences, Inc. |
Phospholipid compounds and methods of making and using the same
|
|
US20250170155A1
(en)
|
2021-08-20 |
2025-05-29 |
Shionogi & Co., Ltd. |
Nucleoside derivatives and prodrugs thereof having viral growth inhibitory action
|
|
CA3244278A1
(en)
|
2022-03-02 |
2023-09-07 |
Gilead Sciences Inc |
COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS
|
|
US12357577B1
(en)
|
2024-02-02 |
2025-07-15 |
Gilead Sciences, Inc. |
Pharmaceutical formulations and uses thereof
|