|
US8124759B2
(en)
*
|
2007-05-09 |
2012-02-28 |
Abbott Laboratories |
Inhibitors of protein kinases
|
|
AU2008251555B2
(en)
|
2007-05-10 |
2012-08-30 |
Biocryst Pharmaceuticals, Inc. |
Tetrahydrofuro [3 4-D] dioxolane compounds for use in the treatment of viral infections and cancer
|
|
TW200942243A
(en)
|
2008-03-05 |
2009-10-16 |
Biocryst Pharm Inc |
Antiviral therapeutic agents
|
|
US20090247750A1
(en)
*
|
2008-03-28 |
2009-10-01 |
Biocryst Pharmaceuticals, Inc. |
Process for preparing nucleoside analogs
|
|
WO2009132123A1
(en)
|
2008-04-23 |
2009-10-29 |
Gilead Sciences, Inc. |
Carba-nucleoside analogs for antiviral treatment
|
|
WO2010002877A2
(en)
*
|
2008-07-03 |
2010-01-07 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
|
KR101724759B1
(ko)
|
2009-02-10 |
2017-04-07 |
길리애드 사이언시즈, 인코포레이티드 |
항바이러스 치료를 위한 카르바-뉴클레오시드 유사체
|
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
NZ599404A
(en)
*
|
2009-09-21 |
2014-02-28 |
Gilead Sciences Inc |
Processes and intermediates for the preparation of 1’-substituted carba-nucleoside analogs
|
|
US8455451B2
(en)
|
2009-09-21 |
2013-06-04 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
EP3150608B1
(en)
*
|
2009-09-21 |
2019-04-10 |
Gilead Sciences, Inc. |
2' -fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
EP2552922A1
(en)
|
2010-03-31 |
2013-02-06 |
Bristol-Myers Squibb Company |
Substituted pyrrolotriazines as protein kinase inhibitors
|
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
|
EP2596004B1
(en)
|
2010-07-19 |
2014-09-10 |
Gilead Sciences, Inc. |
Methods for the preparation of diasteromerically pure phosphoramidate prodrugs
|
|
EP2595980B1
(en)
|
2010-07-22 |
2014-09-03 |
Gilead Sciences, Inc. |
Methods and compounds for treating paramyxoviridae virus infections
|
|
TW201305185A
(zh)
|
2010-09-13 |
2013-02-01 |
Gilead Sciences Inc |
用於抗病毒治療之2’-氟取代之碳-核苷類似物
|
|
EP2619206A1
(en)
|
2010-09-20 |
2013-07-31 |
Gilead Sciences, Inc. |
2' -fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
US8877731B2
(en)
|
2010-09-22 |
2014-11-04 |
Alios Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
|
US8754114B2
(en)
|
2010-12-22 |
2014-06-17 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
|
|
EP2697241B1
(en)
|
2011-04-13 |
2019-06-12 |
Gilead Sciences, Inc. |
1'-substituted pyrimidine n-nucleoside analogs for antiviral treatment
|
|
CA2840518A1
(en)
|
2011-07-01 |
2013-01-10 |
Bayer Intellectual Property Gmbh |
Hydroxymethylaryl-substituted pyrrolotriazines as alk1 inhibitors
|
|
WO2013039920A1
(en)
|
2011-09-12 |
2013-03-21 |
Idenix Pharmaceuticals, Inc. |
Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
|
|
CA2752008A1
(en)
|
2011-09-13 |
2013-03-13 |
Universite De Montreal |
Combination therapy using ribavirin as elf4e inhibitor
|
|
CA3107640A1
(en)
|
2011-12-22 |
2013-06-27 |
Janssen Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof and their use in ameliorating or treating a disease or condition associated with viral infections
|
|
ES2621217T3
(es)
|
2012-03-13 |
2017-07-03 |
Gilead Sciences, Inc. |
Análogos de carba-nucleósido 2'-sustituidos para tratamiento antivírico
|
|
USRE48171E1
(en)
|
2012-03-21 |
2020-08-25 |
Janssen Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
US9441007B2
(en)
|
2012-03-21 |
2016-09-13 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
AR090699A1
(es)
|
2012-04-18 |
2014-12-03 |
Biocryst Pharm Inc |
Compuestos inhibidores de la actividad de la arn polimerasa viral
|
|
EP3176170B1
(en)
|
2012-06-13 |
2018-11-14 |
Incyte Holdings Corporation |
Substituted tricyclic compounds as fgfr inhibitors
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
MX2015005949A
(es)
*
|
2012-11-16 |
2015-09-08 |
Biocryst Pharm Inc |
Nucleosidos que contienen aza-azucar antiviral.
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
SG10201708520YA
(en)
|
2013-04-19 |
2017-12-28 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
CN105829333A
(zh)
|
2013-10-11 |
2016-08-03 |
艾丽奥斯生物制药有限公司 |
取代的核苷、核苷酸及其类似物
|
|
UA119050C2
(uk)
|
2013-11-11 |
2019-04-25 |
Ґілеад Саєнсиз, Інк. |
ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
|
|
WO2015143712A1
(en)
|
2014-03-28 |
2015-10-01 |
Merck Sharp & Dohme Corp. |
4'-substituted nucleoside reverse transcriptase inhibitors
|
|
TWI678369B
(zh)
|
2014-07-28 |
2019-12-01 |
美商基利科學股份有限公司 |
用於治療呼吸道合胞病毒感染之噻吩並[3,2-d]嘧啶、呋喃並[3,2-d]嘧啶及吡咯並[3,2-d]嘧啶化合物類
|
|
TWI673283B
(zh)
|
2014-08-21 |
2019-10-01 |
美商基利科學股份有限公司 |
2’-氯胺基嘧啶酮及嘧啶二酮核苷類
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
WO2016064957A1
(en)
|
2014-10-22 |
2016-04-28 |
Bristol-Myers Squibb Company |
Bicyclic heteroaryl amine compounds as pi3k inhibitors
|
|
ES2749679T3
(es)
|
2014-10-22 |
2020-03-23 |
Bristol Myers Squibb Co |
Compuestos de pirrolotriazina amina sustituidos como inhibidores de PI3k
|
|
TWI767201B
(zh)
*
|
2014-10-29 |
2022-06-11 |
美商基利科學股份有限公司 |
絲狀病毒科病毒感染之治療
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
MX373169B
(es)
|
2015-02-20 |
2020-04-24 |
Incyte Holdings Corp |
Heterociclos bicíclicos como inhibidores de receptores del factor de crecimiento fibroblástico (fgfr).
|
|
MX2017011386A
(es)
|
2015-03-06 |
2018-04-26 |
Atea Pharmaceuticals Inc |
NUCLEÓTIDOS DE PURINA ß-D-2'-DEOXI-2'A-FLUORO-2'-ß-C-SUSTITUIDOS-2 - MODIFICADOS-N6- SUSTITUIDOS PARA EL TRATAMIENTO DEL VIRUS DE LA HEPATITIS C.
|
|
CN104876935B
(zh)
*
|
2015-05-18 |
2017-04-19 |
南方医科大学 |
2‑氨基吡咯并[1,2‑f][1,2,4]三嗪类化合物、合成方法及应用
|
|
ES2909419T3
(es)
|
2015-09-16 |
2022-05-06 |
Gilead Sciences Inc |
Métodos para el tratamiento de infecciones por coronaviridae
|
|
RU2720811C2
(ru)
|
2015-09-23 |
2020-05-13 |
Мерк Шарп И Доум Лимитед |
4'-замещенные нуклеозидные ингибиторы обратной транскриптазы и их получение
|
|
CN108883167A
(zh)
|
2016-03-09 |
2018-11-23 |
加州大学洛杉矶分校港口医学中心生物医学研究所 |
用于预防和治疗外阴阴道念珠菌病的方法和药剂盒
|
|
WO2017156262A1
(en)
*
|
2016-03-09 |
2017-09-14 |
Alios Biopharma, Inc. |
Acyclic antivirals
|
|
MX2018011792A
(es)
|
2016-03-28 |
2019-07-04 |
Incyte Corp |
Compuestos de pirrolotriazina como inhibidores de tyro3, axl y mer (tam).
|
|
WO2018013937A1
(en)
|
2016-07-14 |
2018-01-18 |
Atea Pharmaceuticals, Inc. |
Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
|
RS62943B1
(sr)
|
2016-09-07 |
2022-03-31 |
Atea Pharmaceuticals Inc |
2’-supstituisani-n6-supstituisani purinski nukleotidi za lečenje bolesti izazvanih rnk virusima
|
|
US11617753B2
(en)
|
2016-11-10 |
2023-04-04 |
Oyagen, Inc. |
Methods of treating and inhibiting Ebola virus infection
|
|
IL288737B
(en)
|
2017-02-01 |
2022-09-01 |
Atea Pharmaceuticals Inc |
Hemisulfate nucleotide salt for treatment of hepatitis c virus
|
|
CN110869028B
(zh)
|
2017-03-14 |
2023-01-20 |
吉利德科学公司 |
治疗猫冠状病毒感染的方法
|
|
WO2018204198A1
(en)
|
2017-05-01 |
2018-11-08 |
Gilead Sciences, Inc. |
Crystalline forms of (s) 2 ethylbutyl 2 (((s) (((2r,3s,4r,5r) 5 (4 aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy) phosphoryl)amino)propanoate
|
|
CN107056775A
(zh)
*
|
2017-05-24 |
2017-08-18 |
佛山科学技术学院 |
丙型肝炎病毒ns5b聚合酶抑制剂
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
US10675296B2
(en)
|
2017-07-11 |
2020-06-09 |
Gilead Sciences, Inc. |
Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections
|
|
US11040975B2
(en)
|
2017-12-08 |
2021-06-22 |
Merck Sharp & Dohme Corp. |
Carbocyclic nucleoside reverse transcriptase inhibitors
|
|
TW202012001A
(zh)
|
2018-04-10 |
2020-04-01 |
美商亞堤製藥公司 |
C型肝炎病毒(hcv)感染硬化之患者的治療
|
|
BR112020022373A2
(pt)
|
2018-05-04 |
2021-02-02 |
Incyte Corporation |
sais de um inibidor de fgfr
|
|
CR20240498A
(es)
|
2018-05-04 |
2025-01-08 |
Incyte Corp |
FORMAS SÓLIDAS DE UN INHIBIDOR DE FGFR Y PROCESOS PARA PREPARARLAS (Divisional EXP. 2020-0590)
|
|
CA3122410A1
(en)
|
2018-12-12 |
2020-06-18 |
Janssen Biopharma, Inc. |
Cyclopentyl nucleoside analogs as anti-virals
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021067374A1
(en)
|
2019-10-01 |
2021-04-08 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
JOP20220083A1
(ar)
|
2019-10-14 |
2023-01-30 |
Incyte Corp |
حلقات غير متجانسة ثنائية الحلقة كمثبطات لـ fgfr
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
EP4069696A1
(en)
|
2019-12-04 |
2022-10-12 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
PE20221504A1
(es)
|
2019-12-04 |
2022-09-30 |
Incyte Corp |
Derivados de un inhibidor de fgfr
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
KR20220132608A
(ko)
|
2020-01-27 |
2022-09-30 |
길리애드 사이언시즈, 인코포레이티드 |
SARS CoV-2 감염증을 치료하기 위한 방법
|
|
US11738025B2
(en)
|
2020-02-04 |
2023-08-29 |
Oyagen, Inc. |
Method for treating coronavirus infections
|
|
CN113214262B
(zh)
*
|
2020-02-05 |
2023-07-07 |
华创合成制药股份有限公司 |
一种含有胍基的化合物及其制备方法和用途
|
|
TWI791193B
(zh)
|
2020-02-18 |
2023-02-01 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
AR121356A1
(es)
|
2020-02-18 |
2022-05-11 |
Gilead Sciences Inc |
Compuestos antivirales
|
|
TWI794742B
(zh)
|
2020-02-18 |
2023-03-01 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
TWI874791B
(zh)
|
2020-02-18 |
2025-03-01 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
US10874687B1
(en)
|
2020-02-27 |
2020-12-29 |
Atea Pharmaceuticals, Inc. |
Highly active compounds against COVID-19
|
|
TWI890963B
(zh)
|
2020-03-12 |
2025-07-21 |
美商基利科學股份有限公司 |
1'-氰基核苷之製備方法
|
|
WO2021207049A1
(en)
|
2020-04-06 |
2021-10-14 |
Gilead Sciences, Inc. |
Inhalation formulations of 1'-cyano substituted carbanucleoside analogs
|
|
EP4157272B1
(en)
|
2020-05-29 |
2025-07-02 |
Gilead Sciences, Inc. |
Remdesivir for the treatment of viral infections
|
|
IL299202A
(en)
|
2020-06-24 |
2023-02-01 |
Gilead Sciences Inc |
1'-cyano nucleoside analogs and uses thereof
|
|
EP4183792A4
(en)
*
|
2020-07-14 |
2024-03-20 |
Sichuan University |
NITROGEN-CONTAINING 3-DESOXY-2-KETONE ACID DERIVATIVE, PRODUCTION PROCESS THEREOF AND USE THEREOF
|
|
KR20250111239A
(ko)
|
2020-08-27 |
2025-07-22 |
길리애드 사이언시즈, 인코포레이티드 |
바이러스 감염 치료를 위한 화합물 및 방법
|
|
EP4323405A1
(en)
|
2021-04-12 |
2024-02-21 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
|
US11697666B2
(en)
|
2021-04-16 |
2023-07-11 |
Gilead Sciences, Inc. |
Methods of preparing carbanucleosides using amides
|
|
JP2024522188A
(ja)
|
2021-06-09 |
2024-06-11 |
インサイト・コーポレイション |
Fgfr阻害剤としての三環式ヘテロ環
|
|
EP4352059A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
JP2024525164A
(ja)
|
2021-06-17 |
2024-07-10 |
アテア ファーマシューティカルズ, インコーポレイテッド |
有利な抗hcv併用療法
|
|
US12116380B2
(en)
|
2021-08-18 |
2024-10-15 |
Gilead Sciences, Inc. |
Phospholipid compounds and methods of making and using the same
|
|
KR20240050362A
(ko)
|
2021-08-20 |
2024-04-18 |
시오노기 앤드 컴파니, 리미티드 |
바이러스 증식 억제 작용을 갖는 뉴클레오사이드 유도체 및 그들의 프로드러그
|
|
KR20240154647A
(ko)
|
2022-03-02 |
2024-10-25 |
길리애드 사이언시즈, 인코포레이티드 |
바이러스성 감염 치료를 위한 화합물 및 방법
|
|
US12357577B1
(en)
|
2024-02-02 |
2025-07-15 |
Gilead Sciences, Inc. |
Pharmaceutical formulations and uses thereof
|