|
US8124759B2
(en)
*
|
2007-05-09 |
2012-02-28 |
Abbott Laboratories |
Inhibitors of protein kinases
|
|
AU2008251555B2
(en)
|
2007-05-10 |
2012-08-30 |
Biocryst Pharmaceuticals, Inc. |
Tetrahydrofuro [3 4-D] dioxolane compounds for use in the treatment of viral infections and cancer
|
|
TW200942243A
(en)
*
|
2008-03-05 |
2009-10-16 |
Biocryst Pharm Inc |
Antiviral therapeutic agents
|
|
US20090247750A1
(en)
*
|
2008-03-28 |
2009-10-01 |
Biocryst Pharmaceuticals, Inc. |
Process for preparing nucleoside analogs
|
|
HRP20130048T1
(hr)
|
2008-04-23 |
2013-02-28 |
Gilead Sciences, Inc. |
Karba-nukleozidni analozi za antivirusnu terapiju
|
|
EP2313102A2
(en)
|
2008-07-03 |
2011-04-27 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
|
CA2751277C
(en)
|
2009-02-10 |
2018-10-30 |
Gilead Sciences, Inc. |
Carba-nucleoside analogs for antiviral treatment
|
|
US8455451B2
(en)
|
2009-09-21 |
2013-06-04 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
AU2010295373B2
(en)
*
|
2009-09-21 |
2016-09-29 |
Gilead Sciences, Inc. |
2' -fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
WO2011035250A1
(en)
|
2009-09-21 |
2011-03-24 |
Gilead Sciences, Inc. |
Processes and intermediates for the preparation of 1'-substituted carba-nucleoside analogs
|
|
JP5752232B2
(ja)
|
2010-03-31 |
2015-07-22 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
プロテインキナーゼ阻害剤としての置換ピロロトリアジン化合物
|
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
|
EA025311B1
(ru)
|
2010-07-19 |
2016-12-30 |
Гайлид Сайэнсиз, Инк. |
Способы получения диастереомерно чистых фосфорамидатных пролекарств
|
|
ES2524356T3
(es)
*
|
2010-07-22 |
2014-12-05 |
Gilead Sciences, Inc. |
Métodos y compuestos para tratar infecciones provocadas por virus Paramyxoviridae
|
|
TW201305185A
(zh)
|
2010-09-13 |
2013-02-01 |
吉李德科學股份有限公司 |
用於抗病毒治療之2’-氟取代之碳-核苷類似物
|
|
PE20131165A1
(es)
|
2010-09-20 |
2013-10-14 |
Gilead Sciences Inc |
Analogos de carba-nucleosidos sustituidos con 2'-fluoro para tratamiento antiviral
|
|
EP2619215B1
(en)
|
2010-09-22 |
2018-09-05 |
Alios Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
ES2744587T3
(es)
|
2011-04-13 |
2020-02-25 |
Gilead Sciences Inc |
Análogos de N-nucleósido de pirimidina 1-sustituidos para un tratamiento antiviral
|
|
JP5955953B2
(ja)
|
2011-07-01 |
2016-07-20 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
Alk1阻害剤としてのヒドロキシメチルアリール−置換ピロロトリアジン
|
|
AR088441A1
(es)
|
2011-09-12 |
2014-06-11 |
Idenix Pharmaceuticals Inc |
Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales
|
|
CA2752008A1
(en)
|
2011-09-13 |
2013-03-13 |
Universite De Montreal |
Combination therapy using ribavirin as elf4e inhibitor
|
|
SG10201610936RA
(en)
|
2011-12-22 |
2017-02-27 |
Alios Biopharma Inc |
Substituted nucleosides, nucleotides and analogs thereof
|
|
KR102068856B1
(ko)
|
2012-03-13 |
2020-01-21 |
길리애드 사이언시즈, 인코포레이티드 |
항바이러스 치료를 위한 2'-치환된 카바-뉴클레오시드 유사체
|
|
USRE48171E1
(en)
|
2012-03-21 |
2020-08-25 |
Janssen Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
US9441007B2
(en)
|
2012-03-21 |
2016-09-13 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
AR090699A1
(es)
|
2012-04-18 |
2014-12-03 |
Biocryst Pharm Inc |
Compuestos inhibidores de la actividad de la arn polimerasa viral
|
|
LT3495367T
(lt)
|
2012-06-13 |
2021-02-25 |
Incyte Holdings Corporation |
Pakeistieji tricikliniai junginiai, kaip fgfr inhibitoriai
|
|
WO2014026125A1
(en)
|
2012-08-10 |
2014-02-13 |
Incyte Corporation |
Pyrazine derivatives as fgfr inhibitors
|
|
WO2014078778A2
(en)
*
|
2012-11-16 |
2014-05-22 |
Biocryst Pharmaceuticals, Inc. |
Antiviral azasugar-containing nucleosides
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
LT2986610T
(lt)
|
2013-04-19 |
2018-04-10 |
Incyte Holdings Corporation |
Bicikliniai heterociklai, kaip fgfr inhibitoriai
|
|
JP6562908B2
(ja)
|
2013-10-11 |
2019-08-21 |
ヤンセン バイオファーマ インク. |
置換ヌクレオシド、置換ヌクレオチドおよびその類似体
|
|
UA119050C2
(uk)
|
2013-11-11 |
2019-04-25 |
Ґілеад Саєнсиз, Інк. |
ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
|
|
WO2015143712A1
(en)
|
2014-03-28 |
2015-10-01 |
Merck Sharp & Dohme Corp. |
4'-substituted nucleoside reverse transcriptase inhibitors
|
|
TWI678369B
(zh)
|
2014-07-28 |
2019-12-01 |
美商基利科學股份有限公司 |
用於治療呼吸道合胞病毒感染之噻吩並[3,2-d]嘧啶、呋喃並[3,2-d]嘧啶及吡咯並[3,2-d]嘧啶化合物類
|
|
TWI673283B
(zh)
|
2014-08-21 |
2019-10-01 |
美商基利科學股份有限公司 |
2’-氯胺基嘧啶酮及嘧啶二酮核苷類
|
|
ES2807785T3
(es)
|
2014-10-22 |
2021-02-24 |
Bristol Myers Squibb Co |
Compuestos de heteroarilamina bicíclicos como inhibidores de pi3k
|
|
EP3209665B1
(en)
|
2014-10-22 |
2019-08-14 |
Bristol-Myers Squibb Company |
Substituted pyrrolotriazine amine compounds as pi3k inhibitors
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
TWI740546B
(zh)
*
|
2014-10-29 |
2021-09-21 |
美商基利科學股份有限公司 |
製備核糖苷的方法
|
|
SG11201706287PA
(en)
|
2015-02-20 |
2017-09-28 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
GEP20217282B
(en)
|
2015-03-06 |
2021-08-10 |
Atea Pharmaceuticals Inc |
β-D-2'-DEOXY-2'α-FLUORO-2'-β-C-SUBSTITUTED-2-MODIFIED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT
|
|
CN104876935B
(zh)
*
|
2015-05-18 |
2017-04-19 |
南方医科大学 |
2‑氨基吡咯并[1,2‑f][1,2,4]三嗪类化合物、合成方法及应用
|
|
HRP20220355T1
(hr)
|
2015-09-16 |
2022-05-13 |
Gilead Sciences, Inc. |
Postupci za liječenje infekcija coronaviridae
|
|
MX391226B
(es)
|
2015-09-23 |
2025-03-21 |
Merck Sharp & Dohme Llc |
Inhibidores de transcriptasa inversa de nucleosido 4'-substituido y preparaciones de los mismos.
|
|
AU2017231824B2
(en)
|
2016-03-09 |
2021-07-01 |
Alios Biopharma, Inc. |
Acyclic antivirals
|
|
WO2017155949A1
(en)
|
2016-03-09 |
2017-09-14 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Methods and kits for use in preventing and treating vulvovaginal candidiasis
|
|
CN114456176B
(zh)
|
2016-03-28 |
2024-08-30 |
因赛特公司 |
作为tam抑制剂的吡咯并三嗪化合物
|
|
WO2018013937A1
(en)
|
2016-07-14 |
2018-01-18 |
Atea Pharmaceuticals, Inc. |
Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
|
PT3512863T
(pt)
|
2016-09-07 |
2022-03-09 |
Atea Pharmaceuticals Inc |
Nucleótidos de purina 2'-substituídos-n6-substituídos para tratamento de vírus de rna
|
|
US11617753B2
(en)
|
2016-11-10 |
2023-04-04 |
Oyagen, Inc. |
Methods of treating and inhibiting Ebola virus infection
|
|
CN110248951B
(zh)
|
2017-02-01 |
2022-10-28 |
阿堤亚制药公司 |
用于治疗丙型肝炎病毒的核苷酸半硫酸盐
|
|
CN116036112A
(zh)
|
2017-03-14 |
2023-05-02 |
吉利德科学公司 |
治疗猫冠状病毒感染的方法
|
|
WO2018204198A1
(en)
|
2017-05-01 |
2018-11-08 |
Gilead Sciences, Inc. |
Crystalline forms of (s) 2 ethylbutyl 2 (((s) (((2r,3s,4r,5r) 5 (4 aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy) phosphoryl)amino)propanoate
|
|
CN107056775A
(zh)
*
|
2017-05-24 |
2017-08-18 |
佛山科学技术学院 |
丙型肝炎病毒ns5b聚合酶抑制剂
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
EP4512475A3
(en)
|
2017-07-11 |
2025-05-14 |
Gilead Sciences, Inc. |
Compositions comprising an rna polymerase inhibitor and cyclodextrin for treating viral infections
|
|
US11040975B2
(en)
|
2017-12-08 |
2021-06-22 |
Merck Sharp & Dohme Corp. |
Carbocyclic nucleoside reverse transcriptase inhibitors
|
|
WO2019200005A1
(en)
|
2018-04-10 |
2019-10-17 |
Atea Pharmaceuticals, Inc. |
Treatment of hcv infected patients with cirrhosis
|
|
MX2020011718A
(es)
|
2018-05-04 |
2021-02-15 |
Incyte Corp |
Formas solidas de un inhibidor de receptores del factor de crecimiento de fibroblastos (fgfr) y procesos para prepararlas.
|
|
ES3061844T3
(en)
|
2018-05-04 |
2026-04-07 |
Incyte Corp |
Salts of an fgfr inhibitor
|
|
AU2019398792A1
(en)
|
2018-12-12 |
2021-06-10 |
Janssen Biopharma, Inc. |
Cyclopentyl nucleoside analogs as anti-virals
|
|
US11628162B2
(en)
|
2019-03-08 |
2023-04-18 |
Incyte Corporation |
Methods of treating cancer with an FGFR inhibitor
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
US12122767B2
(en)
|
2019-10-01 |
2024-10-22 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
TWI891666B
(zh)
|
2019-10-14 |
2025-08-01 |
美商英塞特公司 |
作為fgfr抑制劑之雙環雜環
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
CA3163875A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
WO2021113462A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Derivatives of an fgfr inhibitor
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
AU2021214911A1
(en)
|
2020-01-27 |
2022-07-21 |
Gilead Sciences, Inc. |
Methods for treating SARS CoV-2 infections
|
|
US11738025B2
(en)
|
2020-02-04 |
2023-08-29 |
Oyagen, Inc. |
Method for treating coronavirus infections
|
|
CN113214262B
(zh)
*
|
2020-02-05 |
2023-07-07 |
华创合成制药股份有限公司 |
一种含有胍基的化合物及其制备方法和用途
|
|
TWI794742B
(zh)
|
2020-02-18 |
2023-03-01 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
TWI791193B
(zh)
|
2020-02-18 |
2023-02-01 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
TWI874791B
(zh)
|
2020-02-18 |
2025-03-01 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
AU2021224588B2
(en)
|
2020-02-18 |
2024-07-18 |
Gilead Sciences, Inc. |
Antiviral compounds
|
|
US10874687B1
(en)
|
2020-02-27 |
2020-12-29 |
Atea Pharmaceuticals, Inc. |
Highly active compounds against COVID-19
|
|
CN118994170A
(zh)
|
2020-03-12 |
2024-11-22 |
吉利德科学公司 |
制备1'-氰基核苷的方法
|
|
EP4132651B1
(en)
|
2020-04-06 |
2026-03-18 |
Gilead Sciences, Inc. |
Inhalation formulations of 1'-cyano substituted carbanucleoside analogs
|
|
ES3041698T3
(en)
|
2020-05-29 |
2025-11-13 |
Gilead Sciences Inc |
Remdesivir for the treatment of viral infections
|
|
CA3187821A1
(en)
|
2020-06-24 |
2021-12-30 |
Gilead Sciences, Inc. |
1'-cyano nucleoside analogs and uses thereof
|
|
US20230271993A1
(en)
*
|
2020-07-14 |
2023-08-31 |
Sichuan University |
3-deoxy-2-ketoaldonic acid nitrogen-containing derivative, preparation method thereof, and use thereof
|
|
WO2022047065A2
(en)
|
2020-08-27 |
2022-03-03 |
Gilead Sciences, Inc. |
Compounds and methods for treatment of viral infections
|
|
TW202304459A
(zh)
|
2021-04-12 |
2023-02-01 |
美商英塞特公司 |
包含fgfr抑制劑及nectin-4靶向劑之組合療法
|
|
JP7688152B2
(ja)
|
2021-04-16 |
2025-06-03 |
ギリアード サイエンシーズ, インコーポレイテッド |
アミドを使用してカルバヌクレオシドを調製する方法
|
|
EP4352060A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
JP2024522189A
(ja)
|
2021-06-09 |
2024-06-11 |
インサイト・コーポレイション |
Fgfr阻害剤としての三環式ヘテロ環
|
|
BR112023026356A2
(pt)
|
2021-06-17 |
2024-03-05 |
Atea Pharmaceuticals Inc |
Método para tratar vírus da hepatite c ou uma condição resultante de uma infecção por hepatite c, combinação, uso da combinação, composição farmacêutica, e, kit para o tratamento de vírus da hepatite c
|
|
JP7719954B2
(ja)
|
2021-08-18 |
2025-08-06 |
ギリアード サイエンシーズ, インコーポレイテッド |
リン脂質化合物並びにその製造方法及び使用方法
|
|
WO2023022216A1
(ja)
|
2021-08-20 |
2023-02-23 |
塩野義製薬株式会社 |
ウイルス増殖抑制作用を有するヌクレオシド誘導体及びそれらのプロドラッグ
|
|
TW202525810A
(zh)
|
2022-03-02 |
2025-07-01 |
美商基利科學股份有限公司 |
用於治療病毒感染的化合物及方法
|
|
US12357577B1
(en)
|
2024-02-02 |
2025-07-15 |
Gilead Sciences, Inc. |
Pharmaceutical formulations and uses thereof
|