MEP42708A - Method for producing powdery formulations - Google Patents

Method for producing powdery formulations

Info

Publication number
MEP42708A
MEP42708A MEP-427/08A MEP42708A MEP42708A ME P42708 A MEP42708 A ME P42708A ME P42708 A MEP42708 A ME P42708A ME P42708 A MEP42708 A ME P42708A
Authority
ME
Montenegro
Prior art keywords
producing powdery
powdery formulations
formulations
producing
preparation
Prior art date
Application number
MEP-427/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Georg Boeck
Michael Walz
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26007343&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MEP42708(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE2001138022 external-priority patent/DE10138022A1/de
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MEP42708A publication Critical patent/MEP42708A/xx
Publication of ME02762B publication Critical patent/ME02762B/me

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)

Abstract

Pronalazak se odnosi na nov postupak za pripremanje preparata u obliku praha za inhaliranje.
MEP-2008-427A 2000-10-12 2001-10-09 Postupak za pripremanje preparata u obliku praha ME02762B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10050635 2000-10-12
DE2001138022 DE10138022A1 (de) 2001-08-10 2001-08-10 Verfahren zur Herstellung von Pulverformulierungen
PCT/EP2001/011636 WO2002030390A2 (de) 2000-10-12 2001-10-09 Verfahren zur herstellung von pulverformulierungen

Publications (2)

Publication Number Publication Date
MEP42708A true MEP42708A (en) 2011-02-10
ME02762B ME02762B (me) 2011-05-10

Family

ID=26007343

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2008-427A ME02762B (me) 2000-10-12 2001-10-09 Postupak za pripremanje preparata u obliku praha

Country Status (40)

Country Link
US (2) US6585959B2 (hr)
EP (1) EP1326585B2 (hr)
JP (2) JP4986369B2 (hr)
KR (1) KR100849837B1 (hr)
CN (1) CN1269470C (hr)
AR (1) AR034166A1 (hr)
AT (1) ATE319422T1 (hr)
AU (2) AU2002218220B2 (hr)
BG (1) BG66194B1 (hr)
BR (1) BR0114316A (hr)
CA (1) CA2425005C (hr)
CY (1) CY1105037T1 (hr)
CZ (1) CZ300022B6 (hr)
DE (1) DE50109178D1 (hr)
DK (1) DK1326585T4 (hr)
EA (1) EA004689B1 (hr)
EE (1) EE05146B1 (hr)
EG (1) EG24478A (hr)
ES (1) ES2259046T5 (hr)
HK (1) HK1060522A1 (hr)
HR (1) HRP20030277B1 (hr)
HU (1) HU229512B1 (hr)
IL (2) IL154919A0 (hr)
ME (1) ME02762B (hr)
MX (1) MXPA03003219A (hr)
MY (1) MY155912A (hr)
NO (1) NO333719B1 (hr)
NZ (1) NZ525781A (hr)
PE (1) PE20020424A1 (hr)
PL (1) PL204733B1 (hr)
PT (1) PT1326585E (hr)
RS (1) RS50495B (hr)
SA (1) SA01220518B1 (hr)
SI (1) SI1326585T2 (hr)
SK (1) SK285841B6 (hr)
TW (1) TWI283180B (hr)
UA (1) UA75375C2 (hr)
UY (1) UY26960A1 (hr)
WO (1) WO2002030390A2 (hr)
ZA (1) ZA200301349B (hr)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1292281B1 (de) * 2000-10-12 2004-09-08 Boehringer Ingelheim Pharma GmbH & Co.KG Neue tiotropium-haltige inhalationspulver
US6443152B1 (en) * 2001-01-12 2002-09-03 Becton Dickinson And Company Medicament respiratory delivery device
EP1397134A2 (en) * 2001-05-25 2004-03-17 Boehringer Ingelheim Pharma GmbH & Co.KG Combination of a dopamine d2-receptor agonist and tiotropium or a derivative therof for treating obstructive airways
US20030070679A1 (en) * 2001-06-01 2003-04-17 Boehringer Ingelheim Pharma Kg Capsules containing inhalable tiotropium
US20030008001A1 (en) * 2001-06-13 2003-01-09 Boehringer Ingelheim Pharma Kg Process for cleaning hard gelatine capsules
US20030018019A1 (en) * 2001-06-23 2003-01-23 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
DE10141377A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Aufstreuverfahren zur Herstellung von Pulverformulierungen
DE10141376A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Inhalationspulvern
US7309707B2 (en) * 2002-03-20 2007-12-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament
US7244415B2 (en) * 2002-03-28 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations of an anhydrate
NZ536277A (en) * 2002-04-04 2006-03-31 Boehringer Ingelheim Pharma Powder formulations containing tiotropium suitable for inhalation
GB0219513D0 (en) 2002-08-21 2002-10-02 Norton Healthcare Ltd Inhalation compositions including coarse carrier
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
JP4744876B2 (ja) * 2002-08-21 2011-08-10 ノートン・ヘルスケアー リミテッド 乾燥粉末吸入組成物の製造方法
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
EP1599209B1 (en) * 2002-08-21 2011-08-17 Norton Healthcare Limited Inhalation composition
DE10255387A1 (de) * 2002-11-28 2004-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Tiotropium-haltige Pulverformulierung für die Inhalation
US7763280B2 (en) 2002-11-28 2010-07-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing powder formulation for inhalation
DE10351663A1 (de) * 2002-12-20 2004-07-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverförmige Arzneimittel enthaltend ein Tiotropiumsalz und Salmeterolxinafoat
DE10317461A1 (de) 2003-04-16 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US7462367B2 (en) 2003-07-11 2008-12-09 Boehringer Ingelheim International Gmbh Anticholinergic powder formulations for inhalation
DE10331350A1 (de) * 2003-07-11 2005-01-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierungen für die Inhalation enthaltend ein neues Anticholinergikum
US9345664B2 (en) 2003-09-02 2016-05-24 Norton Healthcare Ltd Process for preparing a medicament
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
EP2083007B1 (de) 2003-11-03 2013-04-24 Boehringer Ingelheim International Gmbh Tiotropiumsalze, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittelformulierungen
SI1682541T1 (sl) 2003-11-03 2010-06-30 Boehringer Ingelheim Int Postopek za pripravo tiotropijevih soli
BRPI0417097A (pt) * 2003-12-03 2007-03-13 Microdrug Ag inalador de pó seco de dose previamente medida para medicamentos sensìveis à umidade
DE102004048389A1 (de) 2004-10-01 2006-04-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
RU2007133547A (ru) 2005-02-10 2009-03-20 Глаксо Груп Лимитед (GB) Способы получения лактозы с использованием методов предварительной сортировки и приготовляемые из нее фармацевтические композиции
GB0507835D0 (en) * 2005-04-18 2005-05-25 Solexa Ltd Method and device for nucleic acid sequencing using a planar wave guide
SI1881980T1 (sl) 2005-05-02 2012-12-31 Boehringer Ingelheim International Gmbh Nove kristalinične oblike tiotropijevega bromida
DE102005059602A1 (de) 2005-12-14 2007-06-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Mikronisierung
ES2569359T3 (es) 2007-07-06 2016-05-10 Vectura Delivery Devices Limited Inhalador
EP2264042B1 (en) * 2007-07-27 2012-07-18 Cargill, Incorporated Micronization of polyols
EP2082768A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhaler
EP2082766A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Blister Strip Coil Forming
EP2082771A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhaler
EP2082767A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhaler
EP2082772A1 (en) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhaler
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
EP2662116B1 (en) 2008-05-09 2022-09-21 Nuvaira, Inc. Systems and assemblies for treating a bronchial tree
CN102119238B (zh) * 2008-07-24 2014-05-28 乔治洛德方法研究和开发液化空气有限公司 沉积含过渡金属的膜的方法
TWI491416B (zh) 2008-12-24 2015-07-11 Daiichi Sankyo Co Ltd 吸入用乾燥粉末醫藥組成物
GB0918450D0 (en) 2009-10-21 2009-12-09 Innovata Ltd Composition
CN112089394A (zh) 2009-10-27 2020-12-18 努瓦拉公司 具有可冷却的能量发射组件的递送装置
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
WO2011060200A1 (en) 2009-11-11 2011-05-19 Innovative Pulmonary Solutions, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
EP2575786B1 (en) 2010-06-03 2017-11-15 Sima Patent ve Lisanslama Hizmetleri Ltd.Sti. Process for dry powder formulations
TR201007251A2 (tr) * 2010-09-01 2012-03-21 Bi̇lgi̇ç Mahmut Kalsiyum kanal blokörü formülasyonu.
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
WO2016005443A1 (en) 2014-07-09 2016-01-14 Arven Ilac Sanayi Ve Ticaret A.S. A process for the preparation of formulations for inhalation
ES2776208T3 (es) 2015-12-03 2020-07-29 Tiefenbacher Alfred E Gmbh & Co Kg Procedimiento de mezcladura de polvo seco
EP3826620A4 (en) * 2018-07-12 2023-03-08 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi INHALATION COMPOSITIONS CONTAINING DOPAMINE GONISTS
WO2022146255A1 (en) * 2020-12-31 2022-07-07 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi A process for the preparation of dry powder compositions for inhalation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
US3957965A (en) 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
US3860618A (en) 1967-08-08 1975-01-14 Philip Saxton Hartley Chromone
BE891013A (fr) 1980-11-05 1982-05-05 Fisons Ltd Compositions pharmaceutique
JPS60150823A (ja) * 1984-01-17 1985-08-08 Satake Eng Co Ltd 穀物混合装置
JPH0439388A (ja) * 1990-06-04 1992-02-10 Teijin Ltd 土砂と繊維状物との混合方法
DE4140689B4 (de) * 1991-12-10 2007-11-22 Boehringer Ingelheim Kg Inhalationspulver und Verfahren zu ihrer Herstellung
JPH06198156A (ja) * 1993-01-06 1994-07-19 Nagasaki Pref Gov 噴霧積層混合器
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
GB9322014D0 (en) 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9404945D0 (en) 1994-03-15 1994-04-27 Glaxo Group Ltd Pharmaceutical composition
DE4425255A1 (de) * 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
CA2347856C (en) * 1998-11-13 2009-02-17 Jago Research Ag Dry powder for inhalation
GB9902689D0 (en) 1999-02-08 1999-03-31 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
AU1822002A (en) 2002-04-22
SK4372003A3 (en) 2003-07-01
CN1469733A (zh) 2004-01-21
EE05146B1 (et) 2009-04-15
ES2259046T3 (es) 2006-09-16
KR20030051706A (ko) 2003-06-25
AR034166A1 (es) 2004-02-04
HUP0301268A3 (en) 2005-05-30
CA2425005C (en) 2008-08-05
IL154919A (en) 2011-01-31
HK1060522A1 (en) 2004-08-13
NO333719B1 (no) 2013-09-02
WO2002030390A3 (de) 2002-06-27
EP1326585B1 (de) 2006-03-08
CY1105037T1 (el) 2010-03-03
TWI283180B (en) 2007-07-01
MY155912A (en) 2015-12-15
DK1326585T4 (da) 2011-01-10
MXPA03003219A (es) 2004-12-03
JP2009197025A (ja) 2009-09-03
BG107673A (bg) 2003-11-28
HRP20030277A2 (en) 2005-02-28
BR0114316A (pt) 2003-08-26
SI1326585T2 (sl) 2011-01-31
SK285841B6 (sk) 2007-09-06
US6585959B2 (en) 2003-07-01
DE50109178D1 (de) 2006-05-04
USRE38912E1 (en) 2005-12-06
ES2259046T5 (es) 2011-02-28
NO20031692L (no) 2003-06-06
CZ300022B6 (cs) 2009-01-14
HUP0301268A2 (hu) 2003-10-28
EE200300170A (et) 2003-06-16
EA200300429A1 (ru) 2003-10-30
YU27403A (sh) 2006-03-03
PT1326585E (pt) 2006-05-31
NZ525781A (en) 2004-11-26
JP2004510806A (ja) 2004-04-08
EP1326585B2 (de) 2010-09-29
WO2002030390A2 (de) 2002-04-18
RS50495B (sr) 2010-03-02
DK1326585T3 (da) 2006-05-22
US20020106332A1 (en) 2002-08-08
SI1326585T1 (sl) 2006-06-30
CN1269470C (zh) 2006-08-16
NO20031692D0 (no) 2003-04-11
PE20020424A1 (es) 2002-07-02
JP4986369B2 (ja) 2012-07-25
UA75375C2 (en) 2006-04-17
PL362511A1 (en) 2004-11-02
HRP20030277B1 (hr) 2011-09-30
ATE319422T1 (de) 2006-03-15
BG66194B1 (bg) 2012-01-31
CA2425005A1 (en) 2003-04-04
PL204733B1 (pl) 2010-02-26
UY26960A1 (es) 2002-06-20
KR100849837B1 (ko) 2008-08-01
EA004689B1 (ru) 2004-06-24
IL154919A0 (en) 2003-10-31
ZA200301349B (en) 2004-06-30
SA01220518B1 (ar) 2006-12-10
EG24478A (en) 2009-08-03
HU229512B1 (en) 2014-01-28
ME02762B (me) 2011-05-10
AU2002218220B2 (en) 2006-06-15
EP1326585A2 (de) 2003-07-16

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