SI1881980T1 - Nove kristalinične oblike tiotropijevega bromida - Google Patents

Nove kristalinične oblike tiotropijevega bromida

Info

Publication number
SI1881980T1
SI1881980T1 SI200631474T SI200631474T SI1881980T1 SI 1881980 T1 SI1881980 T1 SI 1881980T1 SI 200631474 T SI200631474 T SI 200631474T SI 200631474 T SI200631474 T SI 200631474T SI 1881980 T1 SI1881980 T1 SI 1881980T1
Authority
SI
Slovenia
Prior art keywords
crystalline forms
tiotropium bromide
novel crystalline
novel
tiotropium
Prior art date
Application number
SI200631474T
Other languages
English (en)
Inventor
Mihaela Maria Pop
Houdayer Stephanie Mulder
Mimoun Lamkadmi
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36693210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1881980(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of SI1881980T1 publication Critical patent/SI1881980T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
SI200631474T 2005-05-02 2006-04-21 Nove kristalinične oblike tiotropijevega bromida SI1881980T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67680705P 2005-05-02 2005-05-02
EP06754794A EP1881980B1 (en) 2005-05-02 2006-04-21 Novel crystalline forms of tiotropium bromide
PCT/EP2006/061763 WO2006117299A2 (en) 2005-05-02 2006-04-21 Novel crystalline forms of tiotropium bromide

Publications (1)

Publication Number Publication Date
SI1881980T1 true SI1881980T1 (sl) 2012-12-31

Family

ID=36693210

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200631474T SI1881980T1 (sl) 2005-05-02 2006-04-21 Nove kristalinične oblike tiotropijevega bromida

Country Status (24)

Country Link
US (1) US7879871B2 (sl)
EP (2) EP2085396A3 (sl)
JP (1) JP5227790B2 (sl)
KR (1) KR20080012932A (sl)
CN (1) CN101166738B (sl)
AR (1) AR053599A1 (sl)
AU (1) AU2006243238B2 (sl)
BR (1) BRPI0609295A2 (sl)
CA (1) CA2606549A1 (sl)
DK (1) DK1881980T3 (sl)
ES (1) ES2393794T3 (sl)
HK (1) HK1114856A1 (sl)
IL (1) IL187055A (sl)
MX (1) MX2007013142A (sl)
NZ (1) NZ563596A (sl)
PE (1) PE20061438A1 (sl)
PL (1) PL1881980T3 (sl)
PT (1) PT1881980E (sl)
RU (1) RU2417224C2 (sl)
SI (1) SI1881980T1 (sl)
TW (1) TWI392674B (sl)
UY (1) UY29506A1 (sl)
WO (1) WO2006117299A2 (sl)
ZA (1) ZA200708048B (sl)

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CN101360744A (zh) * 2005-12-19 2009-02-04 西科尔公司 纯和稳定的噻托溴铵
PL1869035T5 (pl) * 2005-12-19 2016-01-29 Sicor Inc Nowa postać krystaliczna bromku tiotropium i proces jej wytwarzania
CN100999521B (zh) * 2006-01-13 2010-12-08 江苏正大天晴药业股份有限公司 结晶性抗胆碱药噻托溴铵
US20080051582A1 (en) 2006-07-10 2008-02-28 Sicor Inc. Process for the preparation of tiotropium bromide
EP1923393A1 (en) * 2006-11-17 2008-05-21 Boehringer Ingelheim Pharma GmbH & Co. KG Crystalline form of tiotropium bromide and urea
GB0716026D0 (en) * 2007-08-16 2007-09-26 Norton Healthcare Ltd An inhalable medicament
WO2009087419A1 (en) * 2008-01-10 2009-07-16 Generics [Uk] Limited Novel process for the preparation of scopine esters
MX2011004730A (es) * 2008-11-04 2011-05-30 Cipla Ltd Composicion farmaceutica en aerosol.
JP5650120B2 (ja) * 2008-11-04 2015-01-07 シプラ・リミテッド 低い結晶化度を有する臭化チオトロピウム
WO2010101538A2 (en) 2009-03-06 2010-09-10 Bilgic Mahmut New crystal forms
WO2011015883A1 (en) 2009-08-07 2011-02-10 Generics [Uk] Limited Dichloromethane solvate of tiotropium bromide and its use
JP5822831B2 (ja) 2009-08-07 2015-11-24 ジェネリクス・［ユーケー］・リミテッド チオトロピウム臭化物の無水物
TR201007108A2 (tr) * 2010-08-25 2012-03-21 B�Lg�� Mahmut Yeni tiotropyum bromür kristali ve üretim yöntemi.@
TR201102068A2 (tr) 2011-03-03 2012-09-21 Bi̇lgi̇ç Mahmut Tiotropyum bromür içeren kristal maddeler
TR201111589A2 (tr) * 2011-03-03 2012-09-21 Bi̇lgi̇ç Mahmut Tiotropyum bromür susuz kristal formu.
CZ304368B6 (cs) 2011-11-28 2014-04-02 Zentiva, K.S. Směsný solvát tiotropium bromidu a způsob jeho přípravy
GB201200525D0 (en) 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
PT106142B (pt) 2012-02-10 2014-07-18 Hovione Farmaci Ncia S A Processo para a preparação de brometo de tiotrópio
EP2897955B1 (en) * 2012-09-11 2019-11-06 Bilgic, Mahmut New tiotropium bromide crystalline form
RS55919B1 (sr) 2012-11-05 2017-09-29 Zentiva As Stabilizacija solvata tiotropijuma
WO2014165303A1 (en) 2013-04-01 2014-10-09 Pulmatrix, Inc. Tiotropium dry powders
EP2913332A1 (en) * 2014-02-27 2015-09-02 Euticals S.P.A. Crystalline form of tiotropium bromide with lactose
US10034866B2 (en) 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
EP3414243A1 (en) * 2016-02-11 2018-12-19 Sima Patent Ve Lisanslama Hizmetleri Ltd. STI Crystalline form of tiotropium bromide anhydrate
PT115583B (pt) 2019-06-17 2022-05-02 Hovione Farm S A Processo contínuo para a preparação de medicamentos anticolinérgicos

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US20020193392A1 (en) * 2000-11-13 2002-12-19 Christel Schmelzer Pharmaceutical compositions based on tiotropium salts of salts of salmeterol
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Also Published As

Publication number Publication date
CA2606549A1 (en) 2006-11-09
TWI392674B (zh) 2013-04-11
EP2085396A2 (en) 2009-08-05
AU2006243238B2 (en) 2012-05-24
CN101166738A (zh) 2008-04-23
UY29506A1 (es) 2006-11-30
KR20080012932A (ko) 2008-02-12
BRPI0609295A2 (pt) 2010-03-23
EP1881980A2 (en) 2008-01-30
WO2006117299A2 (en) 2006-11-09
PE20061438A1 (es) 2007-01-12
PT1881980E (pt) 2012-12-06
ES2393794T3 (es) 2012-12-28
RU2417224C2 (ru) 2011-04-27
PL1881980T3 (pl) 2013-01-31
AU2006243238A1 (en) 2006-11-09
JP5227790B2 (ja) 2013-07-03
ZA200708048B (en) 2008-10-29
AR053599A1 (es) 2007-05-09
EP1881980B1 (en) 2012-08-22
RU2007144521A (ru) 2009-06-10
US20070092453A1 (en) 2007-04-26
DK1881980T3 (da) 2012-10-01
IL187055A (en) 2012-09-24
IL187055A0 (en) 2008-02-09
WO2006117299A9 (en) 2006-12-28
EP2085396A3 (en) 2009-11-25
US7879871B2 (en) 2011-02-01
MX2007013142A (es) 2008-03-18
WO2006117299A3 (en) 2007-02-22
HK1114856A1 (en) 2008-11-14
TW200708513A (en) 2007-03-01
JP2008540366A (ja) 2008-11-20
CN101166738B (zh) 2011-06-01
NZ563596A (en) 2011-01-28

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