MA41553A - Sulfonylurées, composés apparentés, et leur utilisation - Google Patents
Sulfonylurées, composés apparentés, et leur utilisationInfo
- Publication number
- MA41553A MA41553A MA041553A MA41553A MA41553A MA 41553 A MA41553 A MA 41553A MA 041553 A MA041553 A MA 041553A MA 41553 A MA41553 A MA 41553A MA 41553 A MA41553 A MA 41553A
- Authority
- MA
- Morocco
- Prior art keywords
- related compounds
- sulphonylurides
- nlrp3 inflammasome
- compounds
- useful
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 108091008099 NLRP3 inflammasome Proteins 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 229940100389 Sulfonylurea Drugs 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/56—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
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- A61K31/18—Sulfonamides
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/4164—1,3-Diazoles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
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- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07D207/38—2-Pyrrolones
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Abstract
La présente invention concerne certaines sulfonylurées et des composés apparentés qui ont des propriétés avantageuses et présentent une activité utile dans l'inhibition de l'activation de l'inflammasome nlrp3. Ces composés sont utiles dans le traitement d'un large éventail de troubles dans lesquels le processus d'inflammation, ou plus spécifiquement l'inflammasome nlrp3, ont été impliqués comme facteur clé.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2015900507A AU2015900507A0 (en) | 2015-02-16 | Sulfonylureas and related compounds and use of same | |
EP16751821.6A EP3259253B1 (fr) | 2015-02-16 | 2016-02-16 | Sulfonylurées, composés apparentés, et leur utilisation |
PCT/AU2016/050103 WO2016131098A1 (fr) | 2015-02-16 | 2016-02-16 | Sulfonylurées, composés apparentés, et leur utilisation |
Publications (2)
Publication Number | Publication Date |
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MA41553A true MA41553A (fr) | 2017-12-27 |
MA41553B1 MA41553B1 (fr) | 2020-04-30 |
Family
ID=56691944
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA47440A MA47440B1 (fr) | 2015-02-16 | 2016-02-16 | Sulfonylurées, composés apparentés, et leur utilisation |
MA41553A MA41553B1 (fr) | 2015-02-16 | 2016-02-16 | Sulfonylurées, composés apparentés, et leur utilisation |
MA056473A MA56473A (fr) | 2015-02-16 | 2016-02-16 | Sulfonylurées, composés apparentés, et leur utilisation |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA47440A MA47440B1 (fr) | 2015-02-16 | 2016-02-16 | Sulfonylurées, composés apparentés, et leur utilisation |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA056473A MA56473A (fr) | 2015-02-16 | 2016-02-16 | Sulfonylurées, composés apparentés, et leur utilisation |
Country Status (31)
Country | Link |
---|---|
US (3) | US10538487B2 (fr) |
EP (3) | EP3259253B1 (fr) |
JP (2) | JP6929792B2 (fr) |
KR (1) | KR20170109678A (fr) |
CN (3) | CN113563264A (fr) |
AU (3) | AU2016222278B2 (fr) |
BR (1) | BR112017017610A2 (fr) |
CA (1) | CA2975192A1 (fr) |
CL (2) | CL2017002097A1 (fr) |
CY (1) | CY1122832T1 (fr) |
DK (2) | DK3259253T3 (fr) |
ES (2) | ES2777626T3 (fr) |
HK (1) | HK1249501A1 (fr) |
HR (2) | HRP20200214T1 (fr) |
HU (1) | HUE055755T2 (fr) |
IL (2) | IL273065B2 (fr) |
LT (2) | LT3578547T (fr) |
MA (3) | MA47440B1 (fr) |
MD (1) | MD3259253T2 (fr) |
ME (1) | ME03737B (fr) |
MX (2) | MX2017010528A (fr) |
MY (2) | MY197094A (fr) |
NZ (2) | NZ772349A (fr) |
PE (2) | PE20180160A1 (fr) |
PL (2) | PL3578547T3 (fr) |
PT (2) | PT3578547T (fr) |
RS (2) | RS60048B1 (fr) |
RU (1) | RU2739356C2 (fr) |
SG (2) | SG10202002599XA (fr) |
SI (2) | SI3578547T1 (fr) |
WO (1) | WO2016131098A1 (fr) |
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