MA32731B1 - Céphalosporine possédant un groupe catéchol - Google Patents
Céphalosporine possédant un groupe catécholInfo
- Publication number
- MA32731B1 MA32731B1 MA33798A MA33798A MA32731B1 MA 32731 B1 MA32731 B1 MA 32731B1 MA 33798 A MA33798 A MA 33798A MA 33798 A MA33798 A MA 33798A MA 32731 B1 MA32731 B1 MA 32731B1
- Authority
- MA
- Morocco
- Prior art keywords
- similar
- catéchol
- cephalosporine
- group
- bond
- Prior art date
Links
- HOKIDJSKDBPKTQ-UHFFFAOYSA-N 3-(acetyloxymethyl)-7-[(5-amino-5-carboxypentanoyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C(NC(=O)CCCC(N)C(O)=O)C12 HOKIDJSKDBPKTQ-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D505/10—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D505/12—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 substituted in position 7
- C07D505/14—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 substituted in position 7 with hetero atoms directly attached in position 7
- C07D505/16—Nitrogen atoms
- C07D505/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D505/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D505/24—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by doubly-bound nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/06—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00 containing at least one condensed beta-lactam ring system, provided for by groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00, e.g. a penem or a cepham system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
L'INVENTION PORTE SUR UN COMPOSÉ DE CÉPHÈME REPRÉSENTÉ PAR LA FORMULE (I) [DANS LAQUELLE X REPRÉSENTE N, CH OU C-CL ; T REPRÉSENTE S OU SIMILAIRE ; A ET G REPRÉSENTENT INDÉPENDAMMENT UN ALKYLÈNE INFÉRIEUR OU SIMILAIRE ; B REPRÉSENTE UNE SIMPLE LIAISON OU SIMILAIRE ; D REPRÉSENTE UNE SIMPLE LIAISON, -NR7-CO-, -CO-NR7-, 'NR7-CO-NR7- OU SIMILAIRE ; E REPRÉSENTE UN ALKYLÈNE INFÉRIEUR QUI PEUT ÊTRE SUBSTITUÉ ; F REPRÉSENTE UNE SIMPLE LIAISON OU UN PHÉNYLÈNE QUI PEUT ÊTRE SUBSTITUÉ ; R3, R4, R5 ET R6 REPRÉSENTENT CHACUN INDÉPENDAMMENT UN HYDROGÈNE, UN HALOGÈNE, UN NITRILE OU 'OR8 ; R8 REPRÉSENTE UN HYDROGÈNE OU SIMILAIRE ; ET UN GROUPE REPRÉSENTÉ PAR LA FORMULE (II) REPRÉSENTE UN GROUPE AMMONIUM QUATERNAIRE MONOCYCLIQUE OU À CYCLES CONDENSÉS SATURÉ OU INSATURÉ QUI POSSÈDE AU MOINS UN ATOME N ET QUI PEUT ÊTRE SUBSTITUÉ, LA LIGNE TIRETÉE REPRÉSENTANT UNE LIAISON DANS LE CYCLE], UN ESTER DU COMPOSÉ DE CÉPHÈME, UN PRODUIT PROTÉGÉ DU COMPOSÉ DE CÉPHÈME DANS LEQUEL UN GROUPE AMINO, SITUÉ SUR LE NOYAU DANS LA CHAÎNE DU CÔTÉ DE LA POSITION 7, EST PROTÉGÉ, UN SEL PHARMACEUTIQUEMENT ACCEPTABLE DU COMPOSÉ DE CÉPHÈME, DE L'ESTER OU DU PRODUIT PROTÉGÉ, OU UN SOLVATE DU COMPOSÉ DE CÉPHÈME, DE L'ESTER, DU PRODUIT PROTÉGÉ OU DU SEL PHARMACEUTIQUEMENT ACCEPTABLE, QUI PRÉSENTE UN LARGE SPECTRE ANTIBACTÉRIEN ET EN PARTICULIER QUI PRÉSENTE UNE ACTIVITÉ ANTIBACTÉRIENNE PUISSANTE VIS-À-VIS DE BACTÉRIES À GRAM NÉGATIF PRODUISANT DE LA ß-LACTAMASE. L'INVENTION PORTE ÉGALEMENT SUR UNE COMPOSITION PHARMACEUTIQUE RENFERMANT LE COMPOSÉ DE CÉPHÈME, L'ESTER, LE PRODUIT PROTÉGÉ, LE SEL PHARMACEUTIQUEMENT ACCEPTABLE OU LE SOLVATE.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008280828 | 2008-10-31 | ||
PCT/JP2009/068400 WO2010050468A1 (fr) | 2008-10-31 | 2009-10-27 | Céphalosporine possédant un groupe catéchol |
Publications (1)
Publication Number | Publication Date |
---|---|
MA32731B1 true MA32731B1 (fr) | 2011-10-02 |
Family
ID=42128829
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA33798A MA32731B1 (fr) | 2008-10-31 | 2011-04-29 | Céphalosporine possédant un groupe catéchol |
Country Status (38)
Country | Link |
---|---|
US (1) | US9238657B2 (fr) |
EP (2) | EP2960244B1 (fr) |
JP (2) | JP5498393B2 (fr) |
KR (1) | KR101655961B1 (fr) |
CN (1) | CN102203100B (fr) |
AU (1) | AU2009310959B2 (fr) |
BR (1) | BRPI0921701B8 (fr) |
CA (1) | CA2736953C (fr) |
CL (1) | CL2011000939A1 (fr) |
CO (1) | CO6331443A2 (fr) |
CR (1) | CR20110144A (fr) |
CY (2) | CY1118536T1 (fr) |
DK (1) | DK2960244T3 (fr) |
EA (1) | EA019520B1 (fr) |
ES (2) | ES2564836T3 (fr) |
FI (1) | FIC20200039I1 (fr) |
FR (1) | FR20C1050I2 (fr) |
HR (1) | HRP20161408T1 (fr) |
HU (2) | HUE031802T2 (fr) |
IL (1) | IL211720A (fr) |
LT (2) | LT2960244T (fr) |
MA (1) | MA32731B1 (fr) |
ME (1) | ME02666B (fr) |
MX (1) | MX2011004636A (fr) |
MY (1) | MY155655A (fr) |
NL (1) | NL301067I2 (fr) |
NO (1) | NO2020035I1 (fr) |
NZ (1) | NZ591728A (fr) |
PE (1) | PE20120010A1 (fr) |
PL (1) | PL2960244T3 (fr) |
PT (1) | PT2960244T (fr) |
RS (1) | RS55365B1 (fr) |
SI (1) | SI2960244T1 (fr) |
SM (1) | SMT201600397B (fr) |
TW (1) | TWI535727B (fr) |
UA (1) | UA105190C2 (fr) |
WO (1) | WO2010050468A1 (fr) |
ZA (1) | ZA201102024B (fr) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2935651A1 (fr) | 2007-10-09 | 2009-04-16 | Gladius Pharmaceuticals Corporation | Inhibiteurs de beta-lactamase a large spectre |
PL2960244T3 (pl) | 2008-10-31 | 2017-03-31 | Shionogi & Co., Ltd. | Cefalosporyna mająca grupę katecholową |
US8883773B2 (en) | 2010-04-05 | 2014-11-11 | Shionogi & Co., Ltd. | Cephem compound having pseudo-catechol group |
CA2795322A1 (fr) | 2010-04-05 | 2011-10-13 | Shionogi & Co., Ltd. | Compose de cepheme comprenant un groupe catechol |
WO2011136268A1 (fr) * | 2010-04-28 | 2011-11-03 | 塩野義製薬株式会社 | Nouveaux dérivés de céphème |
CN103502218B (zh) | 2011-03-04 | 2016-08-17 | 生命科技公司 | 用于缀合生物分子的化合物和方法 |
KR101719556B1 (ko) * | 2011-03-30 | 2017-03-24 | 주식회사 레고켐 바이오사이언스 | 신규한 세파로스포린 유도체 및 이를 함유하는 의약 조성물 |
US9334289B2 (en) * | 2011-04-28 | 2016-05-10 | Shionogi & Co., Ltd. | Cephem compound having catechol or pseudo-catechol structure |
WO2013002215A1 (fr) | 2011-06-27 | 2013-01-03 | 塩野義製薬株式会社 | Composé de céphème comportant un groupe pyridinium |
TWI547496B (zh) * | 2011-10-04 | 2016-09-01 | 葛蘭素集團公司 | 抗菌化合物 |
US9290515B2 (en) | 2011-10-04 | 2016-03-22 | Shionogi & Co., Ltd | Cephem derivative having catechol group |
EP2912040A4 (fr) | 2012-10-29 | 2016-06-01 | Shionogi & Co | Procédés de production d'intermédiaires de composés de type 2-alkylcephem |
UY35103A (es) * | 2012-10-29 | 2014-05-30 | Glaxo Group Ltd | Compuestos de cefem 2-sustituidos |
US20150344502A1 (en) * | 2012-12-26 | 2015-12-03 | Shionogi & Co., Ltd. | Cephem compound |
ES2800603T3 (es) | 2013-09-09 | 2021-01-04 | Merck Sharp & Dohme | Tratamiento de infecciones con ceftolozano/tazobactam en sujetos con insuficiencia renal |
CU24441B1 (es) | 2014-03-24 | 2019-09-04 | Novartis Ag | Compuestos orgánicos de monobactam para el tratamiento de infecciones bacterianas |
JP6377570B2 (ja) * | 2014-04-28 | 2018-08-22 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | 2−置換セフェム化合物を含有する医薬組成物 |
WO2015191907A1 (fr) | 2014-06-11 | 2015-12-17 | VenatoRx Pharmaceuticals, Inc. | Inhibiteurs de bêta-lactamases |
JP6783497B2 (ja) * | 2014-09-04 | 2020-11-11 | 塩野義製薬株式会社 | セファロスポリン誘導体の中間体およびその製造方法 |
KR102284990B1 (ko) * | 2014-09-04 | 2021-08-04 | 시오노기세야쿠 가부시키가이샤 | 세팔로스포린 유도체의 염, 그의 결정성 고체 및 그의 제조 방법 |
KR101935186B1 (ko) * | 2014-09-04 | 2019-01-03 | 시오노기세야쿠 가부시키가이샤 | 카테콜기를 갖는 세팔로스포린류를 함유하는 제제 |
JP2018521021A (ja) | 2015-06-11 | 2018-08-02 | バジリア・ファルマスーチカ・インターナショナル・アーゲーBasilea Pharmaceutica International Ag | 排出ポンプ阻害剤及びその治療的使用 |
ES2817537T3 (es) | 2015-09-23 | 2021-04-07 | Novartis Ag | Sales y formas sólidas de un antibiótico monobactámico |
KR102135230B1 (ko) * | 2015-12-10 | 2020-07-17 | 나에자-알지엠 파마슈티칼스 유엘씨 | 세펨 화합물, 그의 제조 및 용도 |
ES2881776T3 (es) | 2016-03-08 | 2021-11-30 | Novartis Ag | Compuestos tricíclicos útiles para tratar las infecciones por ortomixovirus |
WO2017216765A1 (fr) * | 2016-06-17 | 2017-12-21 | Wockhardt Limited | Compositions anti-bactériennes |
JOP20170169A1 (ar) | 2016-08-29 | 2019-01-30 | Novartis Ag | مركبات بيريدازين ثلاثية الحلقة مندمجة تفيد في علاج العدوى بفيروس أورثوميكسو |
US11267826B2 (en) | 2017-05-26 | 2022-03-08 | VenatoRx Pharmaceuticals, Inc. | Penicillin-binding protein inhibitors |
WO2018227178A1 (fr) * | 2017-06-09 | 2018-12-13 | Fob Synthesis, Inc. | Composés de carbapenem et compositions pour le traitement d'infections bactériennes |
WO2019026004A2 (fr) | 2017-08-02 | 2019-02-07 | Novartis Ag | Processus chimique de préparation d'antibiotique monobactame et de ses intermédiaires |
IL305957A (en) | 2018-02-28 | 2023-11-01 | Novartis Ag | History 5-Dion and related compounds as inhibitors of orthomyxovirus replication for the treatment of influenza |
WO2020184399A1 (fr) * | 2019-03-08 | 2020-09-17 | 塩野義製薬株式会社 | Composition pharmaceutique antibactérienne |
CN114401970A (zh) * | 2019-09-06 | 2022-04-26 | 纳布里瓦治疗有限责任公司 | 铁载体头孢菌素缀合物及其用途 |
CA3165565A1 (fr) * | 2020-01-22 | 2021-07-29 | Jian Huang | Compose cephalosporine antibacterien et son application pharmaceutique |
TW202220663A (zh) | 2020-07-28 | 2022-06-01 | 日商鹽野義製藥股份有限公司 | 含有具有鄰苯二酚基之頭孢菌素類的凍結乾燥製劑及其製造方法 |
TW202241913A (zh) * | 2021-01-12 | 2022-11-01 | 大陸商上海森輝醫藥有限公司 | 一種頭孢類抗菌化合物及其製備方法 |
CN113698365A (zh) * | 2021-08-30 | 2021-11-26 | 成都大学 | 一种头孢地尔侧链的制备方法 |
Family Cites Families (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL47168A (en) | 1974-05-09 | 1979-07-25 | Toyama Chemical Co Ltd | Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same |
JPS57118588A (en) | 1981-11-26 | 1982-07-23 | Toyama Chem Co Ltd | Novel cephalosporin |
DE3207840A1 (de) | 1982-03-04 | 1983-09-15 | Hoechst Ag, 6230 Frankfurt | "cephalosporinderivate und verfahren zu ihrer herstellung" |
DE3470314D1 (en) | 1983-01-21 | 1988-05-11 | Beecham Group Plc | Beta-lactam antibacterial agents |
NO165842C (no) | 1984-04-23 | 1991-04-17 | Takeda Chemical Industries Ltd | Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser. |
EP0168177A3 (fr) | 1984-06-28 | 1987-04-01 | Pfizer Limited | Céphalosporines antibiotiques |
NO166283C (no) | 1985-03-01 | 1991-06-26 | Takeda Chemical Industries Ltd | Analogifremgangsmaate for fremstilling av terapeutisk aktive 7beta-(2-(5-amino-1,2,4-tiadiazol-3-yl)-2(z)-substituertoksyiminoacetamido)-3-(heterocyclylmetyl)-3-cefem-4-karboksylsyrederivater. |
JPH068300B2 (ja) * | 1985-08-02 | 1994-02-02 | 萬有製薬株式会社 | 新規セフアロスポリン誘導体 |
EP0211656A3 (fr) | 1985-08-10 | 1988-03-09 | Beecham Group Plc | Dérivés de céphalosporine, procédé pour leur préparation et les compositions pharmaceutiques les contenant |
JPH07107069B2 (ja) * | 1985-09-03 | 1995-11-15 | 大塚化学株式会社 | セフアロスポリン化合物の新規誘導体、その製造法及び該誘導体を含有する医薬組成物 |
CA1299564C (fr) * | 1985-09-03 | 1992-04-28 | Akihiro Shimabayashi | Derive de la cephalosporine |
JPS62158291A (ja) * | 1986-01-07 | 1987-07-14 | Sagami Chem Res Center | セフアロスポリン誘導体 |
ATE92927T1 (de) | 1986-04-14 | 1993-08-15 | Banyu Pharma Co Ltd | 1-carboxy-1-vinyloxyiminoaminothiazolcephalosporin-derivate und deren herstellung. |
DE3750411T2 (de) | 1986-04-14 | 1995-03-16 | Banyu Pharma Co Ltd | Cephalosporinderivate, Verfahren zu ihrer Herstellung und antibakterielle Präparate. |
IE61679B1 (en) | 1987-08-10 | 1994-11-16 | Fujisawa Pharmaceutical Co | Water-soluble antibiotic composition and water-soluble salts of new cephem compounds |
GB8719875D0 (en) | 1987-08-22 | 1987-09-30 | Beecham Group Plc | Compounds |
JPH0228185A (ja) | 1988-04-14 | 1990-01-30 | Tanabe Seiyaku Co Ltd | セファロスポリン化合物及びその合成中間体 |
US5149803A (en) * | 1988-05-10 | 1992-09-22 | Imperial Chemical Industries Plc | Intermediates for cephalosporin compounds |
GB8811055D0 (en) | 1988-05-10 | 1988-06-15 | Ici Plc | Antibiotic compounds |
US5244890A (en) | 1988-06-06 | 1993-09-14 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
PH25965A (en) | 1988-06-06 | 1992-01-13 | Fujisawa Pharmaceutical Co | New cephem compounds which have antimicrobial activities |
GB8813945D0 (en) | 1988-06-13 | 1988-07-20 | Fujisawa Pharmaceutical Co | New cephem compounds & process for preparation thereof |
GB8817653D0 (en) | 1988-07-25 | 1988-09-01 | Fujisawa Pharmaceutical Co | New cephem compounds & processes for preparation thereof |
CA2005787A1 (fr) | 1988-12-29 | 1990-06-29 | Masao Wada | Composes de cephalosporine |
JPH02275886A (ja) | 1988-12-29 | 1990-11-09 | Tanabe Seiyaku Co Ltd | セファロスポリン化合物及びその製法 |
US5143910A (en) | 1989-09-07 | 1992-09-01 | Shionogi & Co., Ltd. | Piperaziniocephalosporins |
GB9005246D0 (en) | 1990-03-08 | 1990-05-02 | Fujisawa Pharmaceutical Co | New cephem compounds and processes for preparation thereof |
US5095012A (en) | 1990-08-23 | 1992-03-10 | Bristol-Myers Squibb Company | Antibiotic c-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof |
US5126336A (en) * | 1990-08-23 | 1992-06-30 | Bristol-Myers Squibb Company | Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof |
US5234920A (en) | 1990-08-23 | 1993-08-10 | Bristol-Myers Squibb Company | Antibiotic C-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof |
US5194433A (en) * | 1990-11-13 | 1993-03-16 | Bristol-Myers Squibb Company | Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof |
GB9111406D0 (en) | 1991-05-28 | 1991-07-17 | Fujisawa Pharmaceutical Co | New cephem compounds and processes for preparation thereof |
GB9118672D0 (en) | 1991-08-30 | 1991-10-16 | Fujisawa Pharmaceutical Co | New cephem compounds and processes for preparation thereof |
EP0628562A1 (fr) | 1993-06-10 | 1994-12-14 | Roussel Uclaf | Céphalosporines comportant en position 7 un radical oxymino substitué, leurs intermédiaires, leurs procédé de préparation et leur application comme médicaments |
WO1999033839A1 (fr) | 1997-12-26 | 1999-07-08 | Cheil Jedang Corporation | Composes derives du cepheme, procede de production associe et composition antibacterienne les contenant |
US6815451B2 (en) | 2001-03-27 | 2004-11-09 | Actelion Pharmaceuticals Ltd. | 1,2,3,4-Tetrahydroisoquinolines derivatives as urotensin II receptor antagonists |
JP2003078440A (ja) | 2001-08-30 | 2003-03-14 | Kyocera Corp | 高周波スイッチ回路 |
TW200305422A (en) | 2002-03-18 | 2003-11-01 | Shionogi & Co | Broad spectrum cefem compounds |
US6713625B2 (en) | 2002-05-23 | 2004-03-30 | Orchid Chemicals & Pharmaceuticals Ltd. | Process for the preparation of cefditoren using the thioester of thiazolylacetic acid |
JP4892926B2 (ja) | 2005-10-25 | 2012-03-07 | 宇部興産株式会社 | スルホン化芳香族ブロック共重合体の製造方法 |
TW200637559A (en) | 2005-03-29 | 2006-11-01 | Shionogi & Co | 3-propenylcefem derivative |
JP4557859B2 (ja) | 2005-09-29 | 2010-10-06 | 富士通株式会社 | 周波数分割多重送受信装置及び送受信方法 |
WO2007096740A2 (fr) | 2006-02-20 | 2007-08-30 | Orchid Research Laboratories Limited | Nouvelles céphalosporines |
WO2007119511A1 (fr) * | 2006-03-16 | 2007-10-25 | Astellas Pharma Inc. | Composés de céphem et leur utilisation en tant qu'agents antimicrobiens |
PL2960244T3 (pl) | 2008-10-31 | 2017-03-31 | Shionogi & Co., Ltd. | Cefalosporyna mająca grupę katecholową |
US8883773B2 (en) | 2010-04-05 | 2014-11-11 | Shionogi & Co., Ltd. | Cephem compound having pseudo-catechol group |
CA2795322A1 (fr) | 2010-04-05 | 2011-10-13 | Shionogi & Co., Ltd. | Compose de cepheme comprenant un groupe catechol |
WO2011136268A1 (fr) | 2010-04-28 | 2011-11-03 | 塩野義製薬株式会社 | Nouveaux dérivés de céphème |
-
2009
- 2009-10-27 PL PL15175084T patent/PL2960244T3/pl unknown
- 2009-10-27 ME MEP-2016-246A patent/ME02666B/fr unknown
- 2009-10-27 PT PT151750841T patent/PT2960244T/pt unknown
- 2009-10-27 NZ NZ591728A patent/NZ591728A/xx unknown
- 2009-10-27 ES ES09823578.1T patent/ES2564836T3/es active Active
- 2009-10-27 EP EP15175084.1A patent/EP2960244B1/fr active Active
- 2009-10-27 RS RS20160919A patent/RS55365B1/sr unknown
- 2009-10-27 EP EP09823578.1A patent/EP2341053B1/fr active Active
- 2009-10-27 MX MX2011004636A patent/MX2011004636A/es active IP Right Grant
- 2009-10-27 PE PE2011000941A patent/PE20120010A1/es active IP Right Grant
- 2009-10-27 KR KR1020117012300A patent/KR101655961B1/ko active IP Right Grant
- 2009-10-27 MY MYPI2011001201A patent/MY155655A/en unknown
- 2009-10-27 ES ES15175084.1T patent/ES2602969T3/es active Active
- 2009-10-27 JP JP2010535799A patent/JP5498393B2/ja active Active
- 2009-10-27 EA EA201170632A patent/EA019520B1/ru unknown
- 2009-10-27 CA CA2736953A patent/CA2736953C/fr active Active
- 2009-10-27 WO PCT/JP2009/068400 patent/WO2010050468A1/fr active Application Filing
- 2009-10-27 SI SI200931549A patent/SI2960244T1/sl unknown
- 2009-10-27 LT LTEP15175084.1T patent/LT2960244T/lt unknown
- 2009-10-27 UA UAA201106802A patent/UA105190C2/ru unknown
- 2009-10-27 HU HUE15175084A patent/HUE031802T2/en unknown
- 2009-10-27 US US13/063,878 patent/US9238657B2/en active Active
- 2009-10-27 BR BRPI0921701A patent/BRPI0921701B8/pt active IP Right Grant
- 2009-10-27 CN CN200980143827.5A patent/CN102203100B/zh active Active
- 2009-10-27 AU AU2009310959A patent/AU2009310959B2/en active Active
- 2009-10-27 DK DK15175084.1T patent/DK2960244T3/en active
- 2009-10-30 TW TW098136792A patent/TWI535727B/zh active
-
2011
- 2011-03-14 IL IL211720A patent/IL211720A/en active IP Right Grant
- 2011-03-17 ZA ZA2011/02024A patent/ZA201102024B/en unknown
- 2011-03-18 CR CR20110144A patent/CR20110144A/es unknown
- 2011-04-27 CL CL2011000939A patent/CL2011000939A1/es unknown
- 2011-04-29 MA MA33798A patent/MA32731B1/fr unknown
- 2011-05-02 CO CO11053320A patent/CO6331443A2/es active IP Right Grant
-
2013
- 2013-12-16 JP JP2013259499A patent/JP2014065732A/ja active Pending
-
2016
- 2016-10-27 HR HRP20161408TT patent/HRP20161408T1/hr unknown
- 2016-11-07 SM SM201600397T patent/SMT201600397B/it unknown
- 2016-11-16 CY CY20161101180T patent/CY1118536T1/el unknown
-
2020
- 2020-10-13 NL NL301067C patent/NL301067I2/nl unknown
- 2020-10-15 FR FR20C1050C patent/FR20C1050I2/fr active Active
- 2020-10-15 LT LTPA2020530C patent/LTPA2020530I1/lt unknown
- 2020-10-16 CY CY2020034C patent/CY2020034I2/el unknown
- 2020-10-19 FI FIC20200039C patent/FIC20200039I1/fi unknown
- 2020-10-21 HU HUS2000042C patent/HUS2000042I1/hu unknown
- 2020-10-21 NO NO2020035C patent/NO2020035I1/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA32731B1 (fr) | Céphalosporine possédant un groupe catéchol | |
MY153910A (en) | BICYCLIC y-AMINO ACID DERIVATIVE | |
CY1112705T1 (el) | Συντηγμενες κυκλικες ενωσεις | |
TW200626559A (en) | Anilino-pyrimidine analogs | |
UA105185C2 (uk) | Піроли | |
ECSP099091A (es) | Profarmaco de compuesto de cinamida | |
EA201070246A1 (ru) | Циклические аминные соединения | |
NZ627878A (en) | P2x4 receptor antagonist | |
MY169043A (en) | New dihydroquinoline-2-one derivatives | |
CY1113716T1 (el) | Νεα μεθοδος συνθεσης της αγομελατινης | |
CO6680665A2 (es) | Derivados de 5-yodo-triazol | |
TW201129552A (en) | Salt and photoresist composition containing the same | |
EA201171328A1 (ru) | Производное замещенного изохинолина | |
MX2014013074A (es) | Compuestos de n- (tetrazol-5-il) - y n- (triazol-5-il) arilcarboxamida sustituidos y su uso como herbicidas. | |
MY169267A (en) | New aryl-quinoline derivatives | |
EP2575815A4 (fr) | Inhibiteurs du transporteur 1 de la glycine, procédés de fabrication associés, et utilisations associées | |
UA117151C2 (uk) | N-ациліміногетероциклічні сполуки | |
EA200900946A1 (ru) | Новый способ синтеза агомелатина | |
MA32956B1 (fr) | Derives de 5-amino-2-(1-hydroxyethyl)-tetrahydropyrane | |
MY161134A (en) | Piperazine compound having a pgds inhibitory effect | |
ATE500212T1 (de) | Bisphenol monoester | |
MY160882A (en) | Biocidal composition and method | |
MX2013005753A (es) | Nuevos derivados de biaril amida. | |
TW201129532A (en) | Salt and photoresist composition containing the same | |
CY1111573T1 (el) | Νεα μεθοδος συνθεσης της αγομελατινης |