SMT201600397B - Cefalosporina avente un gruppo catecolo - Google Patents

Cefalosporina avente un gruppo catecolo

Info

Publication number
SMT201600397B
SMT201600397B SM201600397T SM201600397T SMT201600397B SM T201600397 B SMT201600397 B SM T201600397B SM 201600397 T SM201600397 T SM 201600397T SM 201600397 T SM201600397 T SM 201600397T SM T201600397 B SMT201600397 B SM T201600397B
Authority
SM
San Marino
Prior art keywords
catecolo
cephalosporin
group
catecolo group
Prior art date
Application number
SM201600397T
Other languages
English (en)
Inventor
Yasuhiro Nishitani
Kenji Yamawaki
Yusuke Takeoka
Hideki Sugimoto
Shinya Hisakawa
Toshiaki Aoki
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42128829&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201600397(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of SMT201600397B publication Critical patent/SMT201600397B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D505/10—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D505/12—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 substituted in position 7
    • C07D505/14—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 substituted in position 7 with hetero atoms directly attached in position 7
    • C07D505/16—Nitrogen atoms
    • C07D505/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D505/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D505/24—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by doubly-bound nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/06—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00 containing at least one condensed beta-lactam ring system, provided for by groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00, e.g. a penem or a cepham system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SM201600397T 2008-10-31 2016-11-07 Cefalosporina avente un gruppo catecolo SMT201600397B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008280828 2008-10-31

Publications (1)

Publication Number Publication Date
SMT201600397B true SMT201600397B (it) 2017-01-10

Family

ID=42128829

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201600397T SMT201600397B (it) 2008-10-31 2016-11-07 Cefalosporina avente un gruppo catecolo

Country Status (38)

Country Link
US (1) US9238657B2 (it)
EP (2) EP2341053B1 (it)
JP (2) JP5498393B2 (it)
KR (1) KR101655961B1 (it)
CN (1) CN102203100B (it)
AU (1) AU2009310959B2 (it)
BR (1) BRPI0921701B8 (it)
CA (1) CA2736953C (it)
CL (1) CL2011000939A1 (it)
CO (1) CO6331443A2 (it)
CR (1) CR20110144A (it)
CY (2) CY1118536T1 (it)
DK (1) DK2960244T3 (it)
EA (1) EA019520B1 (it)
ES (2) ES2602969T3 (it)
FI (1) FIC20200039I1 (it)
FR (1) FR20C1050I2 (it)
HR (1) HRP20161408T1 (it)
HU (2) HUE031802T2 (it)
IL (1) IL211720A (it)
LT (2) LT2960244T (it)
MA (1) MA32731B1 (it)
ME (1) ME02666B (it)
MX (1) MX2011004636A (it)
MY (1) MY155655A (it)
NL (1) NL301067I2 (it)
NO (1) NO2020035I1 (it)
NZ (1) NZ591728A (it)
PE (1) PE20120010A1 (it)
PL (1) PL2960244T3 (it)
PT (1) PT2960244T (it)
RS (1) RS55365B1 (it)
SI (1) SI2960244T1 (it)
SM (1) SMT201600397B (it)
TW (1) TWI535727B (it)
UA (1) UA105190C2 (it)
WO (1) WO2010050468A1 (it)
ZA (1) ZA201102024B (it)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8883772B2 (en) 2007-10-09 2014-11-11 Sopharmia, Inc. Broad spectrum beta-lactamase inhibitors
PE20120010A1 (es) * 2008-10-31 2012-02-07 Shionogi & Co Cefalosporinas que tienen un grupo catecol
US8883773B2 (en) 2010-04-05 2014-11-11 Shionogi & Co., Ltd. Cephem compound having pseudo-catechol group
US9145425B2 (en) * 2010-04-05 2015-09-29 Shionogi & Co., Ltd. Cephem compound having catechol group
JP5852562B2 (ja) * 2010-04-28 2016-02-03 塩野義製薬株式会社 新規なセフェム誘導体
US20150072396A1 (en) * 2011-03-04 2015-03-12 Life Technologies Corporation Compounds and Methods for Conjugation of Biomolecules
KR101719556B1 (ko) * 2011-03-30 2017-03-24 주식회사 레고켐 바이오사이언스 신규한 세파로스포린 유도체 및 이를 함유하는 의약 조성물
JP6006201B2 (ja) * 2011-04-28 2016-10-12 塩野義製薬株式会社 カテコールまたは擬似カテコール構造を有する新規セフェム化合物
WO2013002215A1 (ja) 2011-06-27 2013-01-03 塩野義製薬株式会社 ピリジニウム基を有するセフェム化合物
TWI547496B (zh) 2011-10-04 2016-09-01 葛蘭素集團公司 抗菌化合物
CN103958527A (zh) 2011-10-04 2014-07-30 盐野义制药株式会社 具有儿茶酚基团的头孢烯衍生物
CN104854113A (zh) 2012-10-29 2015-08-19 盐野义制药株式会社 2-烷基头孢烯化合物的中间体的生产方法
UY35103A (es) * 2012-10-29 2014-05-30 Glaxo Group Ltd Compuestos de cefem 2-sustituidos
US20150344502A1 (en) * 2012-12-26 2015-12-03 Shionogi & Co., Ltd. Cephem compound
AU2014233637A1 (en) 2013-09-09 2015-03-26 Merck Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
ES2719136T3 (es) 2014-03-24 2019-07-08 Novartis Ag Compuestos orgánicos de monobactam para el tratamiento de infecciones bacterianas
JP6377570B2 (ja) * 2014-04-28 2018-08-22 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ ２−置換セフェム化合物を含有する医薬組成物
KR102396753B1 (ko) 2014-06-11 2022-05-12 베나토알엑스 파마슈티컬스, 인크. 베타-락타마제 억제제
CN106661052B (zh) * 2014-09-04 2021-05-11 盐野义制药株式会社 头孢菌素衍生物的中间体及其制造方法
ES2893424T3 (es) * 2014-09-04 2022-02-09 Shionogi & Co Sal de derivado de cefalosporina, su forma sólida cristalina y método para producirla
JP6218204B2 (ja) * 2014-09-04 2017-10-25 塩野義製薬株式会社 カテコール基を有するセファロスポリン類を含有する製剤
US10464896B2 (en) 2015-06-11 2019-11-05 Basilea Pharmaceutica International AG Efflux-pump inhibitors and therapeutic uses thereof
EA202092620A1 (ru) 2015-09-23 2021-06-30 Новартис Аг Соли и твердые формы монобактамного антибиотика
BR112018009725A8 (pt) * 2015-12-10 2019-02-26 Naeja Rgm Pharmaceuticals Ulc compostos de cefém, sua produção e uso
JP6918819B2 (ja) 2016-03-08 2021-08-11 ノバルティス アーゲー オルトミクソウイルス感染の処置に有用な三環式化合物
US20200316083A1 (en) * 2016-06-17 2020-10-08 Wockhardt Limited Antibacterial compositions
JOP20170169A1 (ar) 2016-08-29 2019-01-30 Novartis Ag مركبات بيريدازين ثلاثية الحلقة مندمجة تفيد في علاج العدوى بفيروس أورثوميكسو
US11267826B2 (en) 2017-05-26 2022-03-08 VenatoRx Pharmaceuticals, Inc. Penicillin-binding protein inhibitors
JP7326164B2 (ja) * 2017-06-09 2023-08-15 フオブ・シンセシス・インコーポレーテツド 細菌感染治療のためのカルバペネム化合物及び組成物
AU2018311521B2 (en) 2017-08-02 2022-03-03 Novartis Ag Process for preparing 1 -(((Z)-(1 -(2-aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-y l)methyl)-1 -sulfoazetidin-3- yl)amino)ethylidene)amino)oxy)cyclopropane carboxylic acid
AU2019227250B2 (en) 2018-02-28 2021-11-04 Novartis Ag 10-(di(phenyl)methyl)-4-hydroxy-8,9,9a,10-tetrahydro-7H-pyrrolo[1 ',2':4,5]pyrazino[1,2-b]pyridazine-3,5-dione derivatives and related compounds as inhibitors of the orthomyxovirus replication for treating influenza
WO2019226931A1 (en) 2018-05-25 2019-11-28 VenatoRx Pharmaceuticals, Inc. Penicillin-binding protein inhibitors
WO2020184399A1 (ja) * 2019-03-08 2020-09-17 塩野義製薬株式会社 抗菌用医薬組成物
CA3147354A1 (en) * 2019-09-06 2021-03-11 Rosemarie Riedl Siderophore cephalosporin conjugates and uses thereof
CN114846016B (zh) * 2020-01-22 2024-12-13 上海森辉医药有限公司 头孢类抗菌化合物及其在医药上的应用
TW202220663A (zh) * 2020-07-28 2022-06-01 日商鹽野義製藥股份有限公司 含有具有鄰苯二酚基之頭孢菌素類的凍結乾燥製劑及其製造方法
CA3204655A1 (en) 2021-01-12 2022-07-21 Jian Huang Cephalosporin antibacterial compound and preparation method therefor
CN113698365A (zh) * 2021-08-30 2021-11-26 成都大学 一种头孢地尔侧链的制备方法
CN121127245A (zh) * 2023-06-01 2025-12-12 江苏恒瑞医药股份有限公司 一种包含头孢类抗菌化合物的药物组合物
CN117024377B (zh) * 2023-08-15 2025-04-29 济南大学 一种2-氯-3,4-二对甲氧苯甲氧基-n-(2-(1-吡咯烷)乙基)苯甲酰胺的制备方法
CN117069638A (zh) * 2023-08-17 2023-11-17 济南大学 一种头孢地尔中间体的制备方法
CN117088764A (zh) * 2023-08-24 2023-11-21 济南大学 一种头孢地尔关键中间体的合成和后处理方法
US12225906B1 (en) 2024-09-26 2025-02-18 Terry Earl Brady Pathogenic affinity pathway of infectious or parasitic organisms for nanogram and picogram dosimetry prophylaxis or cure

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL47168A (en) 1974-05-09 1979-07-25 Toyama Chemical Co Ltd Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same
JPS57118588A (en) 1981-11-26 1982-07-23 Toyama Chem Co Ltd Novel cephalosporin
DE3207840A1 (de) 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "cephalosporinderivate und verfahren zu ihrer herstellung"
AU2361184A (en) 1983-01-21 1984-07-26 Beecham Group Plc Disubstituted 6-penicillins and 7-cephalosporins
NO165842C (no) 1984-04-23 1991-04-17 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser.
EP0168177A3 (en) 1984-06-28 1987-04-01 Pfizer Limited Cephalosporin antibiotics
NO166283C (no) 1985-03-01 1991-06-26 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive 7beta-(2-(5-amino-1,2,4-tiadiazol-3-yl)-2(z)-substituertoksyiminoacetamido)-3-(heterocyclylmetyl)-3-cefem-4-karboksylsyrederivater.
JPH068300B2 (ja) 1985-08-02 1994-02-02 萬有製薬株式会社 新規セフアロスポリン誘導体
EP0211656A3 (en) 1985-08-10 1988-03-09 Beecham Group Plc Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
JPH07107069B2 (ja) * 1985-09-03 1995-11-15 大塚化学株式会社 セフアロスポリン化合物の新規誘導体、その製造法及び該誘導体を含有する医薬組成物
CA1299564C (en) * 1985-09-03 1992-04-28 Akihiro Shimabayashi Cephalosporin derivative
JPS62158291A (ja) * 1986-01-07 1987-07-14 Sagami Chem Res Center セフアロスポリン誘導体
ATE92927T1 (de) 1986-04-14 1993-08-15 Banyu Pharma Co Ltd 1-carboxy-1-vinyloxyiminoaminothiazolcephalosporin-derivate und deren herstellung.
ATE110386T1 (de) 1986-04-14 1994-09-15 Banyu Pharma Co Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und antibakterielle präparate.
IE61679B1 (en) * 1987-08-10 1994-11-16 Fujisawa Pharmaceutical Co Water-soluble antibiotic composition and water-soluble salts of new cephem compounds
GB8719875D0 (en) 1987-08-22 1987-09-30 Beecham Group Plc Compounds
JPH0228185A (ja) 1988-04-14 1990-01-30 Tanabe Seiyaku Co Ltd セファロスポリン化合物及びその合成中間体
US5149803A (en) * 1988-05-10 1992-09-22 Imperial Chemical Industries Plc Intermediates for cephalosporin compounds
GB8811055D0 (en) 1988-05-10 1988-06-15 Ici Plc Antibiotic compounds
PH25965A (en) * 1988-06-06 1992-01-13 Fujisawa Pharmaceutical Co New cephem compounds which have antimicrobial activities
US5244890A (en) * 1988-06-06 1993-09-14 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
GB8813945D0 (en) 1988-06-13 1988-07-20 Fujisawa Pharmaceutical Co New cephem compounds & process for preparation thereof
GB8817653D0 (en) * 1988-07-25 1988-09-01 Fujisawa Pharmaceutical Co New cephem compounds & processes for preparation thereof
CA2005787A1 (en) 1988-12-29 1990-06-29 Masao Wada Cephalosporin compounds
JPH02275886A (ja) 1988-12-29 1990-11-09 Tanabe Seiyaku Co Ltd セファロスポリン化合物及びその製法
US5143910A (en) 1989-09-07 1992-09-01 Shionogi & Co., Ltd. Piperaziniocephalosporins
GB9005246D0 (en) 1990-03-08 1990-05-02 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
US5234920A (en) 1990-08-23 1993-08-10 Bristol-Myers Squibb Company Antibiotic C-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof
US5126336A (en) 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
US5095012A (en) 1990-08-23 1992-03-10 Bristol-Myers Squibb Company Antibiotic c-7 catechol-substituted cephalosporin compounds, compositions, and method of use thereof
US5194433A (en) * 1990-11-13 1993-03-16 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
GB9111406D0 (en) 1991-05-28 1991-07-17 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
GB9118672D0 (en) 1991-08-30 1991-10-16 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
EP0628562A1 (fr) 1993-06-10 1994-12-14 Roussel Uclaf Céphalosporines comportant en position 7 un radical oxymino substitué, leurs intermédiaires, leurs procédé de préparation et leur application comme médicaments
AU1694099A (en) 1997-12-26 1999-07-19 Cheil Jedang Corporation Cephem derivatives and a method for producing the compounds and an antibacterialcomposition containing the compounds
WO2002076979A1 (en) 2001-03-27 2002-10-03 Actelion Pharmaceuticals Ltd 1,2,3,4-tetrahydroisoquinolines derivatives as urotensin ii receptor antagonists
JP2003078440A (ja) 2001-08-30 2003-03-14 Kyocera Corp 高周波スイッチ回路
TW200305422A (en) 2002-03-18 2003-11-01 Shionogi & Co Broad spectrum cefem compounds
US6713625B2 (en) 2002-05-23 2004-03-30 Orchid Chemicals & Pharmaceuticals Ltd. Process for the preparation of cefditoren using the thioester of thiazolylacetic acid
JP4892926B2 (ja) 2005-10-25 2012-03-07 宇部興産株式会社 スルホン化芳香族ブロック共重合体の製造方法
TW200637559A (en) 2005-03-29 2006-11-01 Shionogi & Co 3-propenylcefem derivative
JP4557859B2 (ja) 2005-09-29 2010-10-06 富士通株式会社 周波数分割多重送受信装置及び送受信方法
WO2007096740A2 (en) 2006-02-20 2007-08-30 Orchid Research Laboratories Limited Novel cephalosporins
JP2009530228A (ja) 2006-03-16 2009-08-27 アステラス製薬株式会社 セフェム化合物および抗菌薬としての利用
PE20120010A1 (es) 2008-10-31 2012-02-07 Shionogi & Co Cefalosporinas que tienen un grupo catecol
US8883773B2 (en) * 2010-04-05 2014-11-11 Shionogi & Co., Ltd. Cephem compound having pseudo-catechol group
US9145425B2 (en) * 2010-04-05 2015-09-29 Shionogi & Co., Ltd. Cephem compound having catechol group
JP5852562B2 (ja) * 2010-04-28 2016-02-03 塩野義製薬株式会社 新規なセフェム誘導体

Also Published As

Publication number Publication date
FR20C1050I2 (fr) 2021-10-15
UA105190C2 (ru) 2014-04-25
BRPI0921701A2 (pt) 2020-08-11
LTPA2020530I1 (lt) 2020-11-10
JPWO2010050468A1 (ja) 2012-03-29
FR20C1050I1 (it) 2020-11-27
HUS2000042I1 (hu) 2020-11-30
TWI535727B (zh) 2016-06-01
ES2602969T3 (es) 2017-02-23
MX2011004636A (es) 2011-06-20
FIC20200039I1 (fi) 2020-10-19
CA2736953A1 (en) 2010-05-06
NZ591728A (en) 2012-12-21
EP2341053B1 (en) 2016-01-13
JP2014065732A (ja) 2014-04-17
HRP20161408T1 (hr) 2016-12-02
CA2736953C (en) 2017-07-11
BRPI0921701B8 (pt) 2022-11-29
ES2564836T3 (es) 2016-03-29
EA201170632A1 (ru) 2011-12-30
US9238657B2 (en) 2016-01-19
KR101655961B1 (ko) 2016-09-08
MA32731B1 (fr) 2011-10-02
AU2009310959A1 (en) 2010-05-06
LTC2960244I2 (lt) 2023-10-10
NL301067I2 (nl) 2020-10-28
CN102203100B (zh) 2014-08-27
CN102203100A (zh) 2011-09-28
CY2020034I1 (el) 2020-11-25
EP2960244A1 (en) 2015-12-30
EA019520B1 (ru) 2014-04-30
US20110190254A1 (en) 2011-08-04
DK2960244T3 (en) 2016-11-28
TW201020259A (en) 2010-06-01
IL211720A0 (en) 2011-06-30
IL211720A (en) 2015-01-29
HUE031802T2 (en) 2017-08-28
PL2960244T3 (pl) 2017-03-31
NO2020035I1 (no) 2020-10-21
PE20120010A1 (es) 2012-02-07
CL2011000939A1 (es) 2011-09-16
CY2020034I2 (el) 2021-05-05
LT2960244T (lt) 2016-11-25
CY1118536T1 (el) 2017-07-12
EP2960244B1 (en) 2016-09-14
CO6331443A2 (es) 2011-10-20
ME02666B (me) 2017-06-20
ZA201102024B (en) 2014-08-27
MY155655A (en) 2015-11-13
EP2341053A4 (en) 2012-08-08
AU2009310959B2 (en) 2015-05-07
JP5498393B2 (ja) 2014-05-21
KR20110090982A (ko) 2011-08-10
NL301067I1 (it) 2020-10-13
WO2010050468A1 (ja) 2010-05-06
EP2341053A1 (en) 2011-07-06
RS55365B1 (sr) 2017-03-31
BRPI0921701B1 (pt) 2022-05-03
PT2960244T (pt) 2016-11-02
CR20110144A (es) 2011-09-09
SI2960244T1 (sl) 2017-02-28

Similar Documents

Publication Publication Date Title
SMT201600397B (it) Cefalosporina avente un gruppo catecolo
IT1393131B1 (it) Controvento a ingobbamento limitato
DK2254624T3 (da) Automatisk injektor
BRPI0909317A2 (pt) imidazoquinolinas substituídas
DK2493353T3 (da) En møbel
FI20086158A0 (fi) Imidatsopyridiinijohdannaiset
DK2429882T3 (da) Forbindelsesanordning
DE112010001215A5 (de) Gurtaufrollersystem mit einsteuerglied
IT1395333B1 (it) Gruppo pedale-pedivella per biciclette.
IT1396031B1 (it) Gruppo doccetta
IT1391127B1 (it) Gruppo cassa automatico perfezionato
FI20085741A0 (fi) Kuvantamisjärjestely
GB0801029D0 (en) A house
IT1391987B1 (it) Gruppo reggispinta
IT1397375B1 (it) Cassero a disarmo rapido
FR2947315B1 (fr) Palier a roulement
GB0801028D0 (en) A house
FR2926196B1 (fr) Meuble a langer multifonctions
FI20085554A0 (fi) Laiva
ITVI20080026U1 (it) Tornio a revolver
FI7994U1 (fi) Biotiinianalogeja
IT1399306B1 (it) Gruppo tenda a rullo
IT1397839B1 (it) Gruppo rubinetto ad incasso
FI8370U1 (fi) Kuristin
IT1391295B1 (it) Gruppo infusore