MA32656B1 - Nouveaux composes chimiques - Google Patents

Nouveaux composes chimiques

Info

Publication number
MA32656B1
MA32656B1 MA33729A MA33729A MA32656B1 MA 32656 B1 MA32656 B1 MA 32656B1 MA 33729 A MA33729 A MA 33729A MA 33729 A MA33729 A MA 33729A MA 32656 B1 MA32656 B1 MA 32656B1
Authority
MA
Morocco
Prior art keywords
chemical compounds
new chemical
novel compounds
compounds
excessive
Prior art date
Application number
MA33729A
Other languages
Arabic (ar)
English (en)
Inventor
Steffen Steurer
Peter Ettmayer
Andreas Mantoulidis
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40019293&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32656(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MA32656B1 publication Critical patent/MA32656B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne de nouveaux composés représentés par la formule (i) dans laquelle les groupes r1 à r3, x1, x2, x3 et l1 ont la signification donnée dans la revendication 1, ces nouveaux composés étant appropriés pour traiter des maladies caractérisées par une prolifération cellulaire excessive ou anormale; et l'utilisation de tels composés dans un tel traitement.
MA33729A 2008-09-29 2011-03-28 Nouveaux composes chimiques MA32656B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08165437 2008-09-29
PCT/EP2009/062551 WO2010034838A2 (fr) 2008-09-29 2009-09-28 Nouveaux composés chimiques

Publications (1)

Publication Number Publication Date
MA32656B1 true MA32656B1 (fr) 2011-09-01

Family

ID=40019293

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33729A MA32656B1 (fr) 2008-09-29 2011-03-28 Nouveaux composes chimiques

Country Status (20)

Country Link
US (1) US8778929B2 (fr)
EP (1) EP2350052B1 (fr)
JP (1) JP5603869B2 (fr)
KR (1) KR20110063574A (fr)
CN (1) CN102227421A (fr)
AR (1) AR073700A1 (fr)
AU (1) AU2009295855A1 (fr)
BR (1) BRPI0920608A2 (fr)
CA (1) CA2738448A1 (fr)
CL (1) CL2011000691A1 (fr)
CO (1) CO6351739A2 (fr)
EA (1) EA201100564A1 (fr)
EC (1) ECSP11010930A (fr)
IL (1) IL211744A0 (fr)
MA (1) MA32656B1 (fr)
MX (1) MX2011003292A (fr)
PE (1) PE20110294A1 (fr)
TW (1) TW201018670A (fr)
UY (1) UY32146A (fr)
WO (1) WO2010034838A2 (fr)

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TW201014860A (en) 2008-09-08 2010-04-16 Boehringer Ingelheim Int New chemical compounds
PE20110294A1 (es) 2008-09-29 2011-05-26 Boehringer Ingelheim Int Compuestos heterociclicos como inhibidores de enzimas de senal especifica
CA2752265A1 (fr) 2009-02-17 2010-08-26 Boehringer Ingelheim International Gmbh Derives pyrimido-[5,4-d]-pyrimidine pour l'inhibition des tyrosine-kinases
JP2011057661A (ja) 2009-08-14 2011-03-24 Bayer Cropscience Ag 殺虫性カルボキサミド類
AR077975A1 (es) 2009-08-28 2011-10-05 Irm Llc Derivados de pirazol pirimidina y composiciones como inhibidores de cinasa de proteina
EP2552905B1 (fr) 2010-03-26 2016-10-05 Boehringer Ingelheim International GmbH Inhibiteurs de la kinase B-Raf
WO2011117382A1 (fr) * 2010-03-26 2011-09-29 Boehringer Ingelheim International Gmbh Pyridyltriazoles
US8710055B2 (en) 2010-12-21 2014-04-29 Boehringer Ingelheim International Gmbh Triazolylphenyl sulfonamides as serine/threonine kinase inhibitors
US8889684B2 (en) 2011-02-02 2014-11-18 Boehringer Ingelheim International Gmbh Azaindolylphenyl sulfonamides as serine/threonine kinase inhibitors
WO2013038390A1 (fr) * 2011-09-16 2013-03-21 Novartis Ag Hétérocyclyle carboxamides n-substitués
CA2855243C (fr) 2011-11-11 2020-04-14 Novartis Ag Procede de traitement d'une maladie proliferative
LT2782557T (lt) 2011-11-23 2018-12-27 Array Biopharma, Inc. Farmacinės kompozicijos
CA2769821C (fr) 2012-02-28 2020-08-11 Michael Hatzinikolas Ensemble structurel a liberation automatique
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WO2013171642A1 (fr) 2012-05-15 2013-11-21 Novartis Ag Dérivés de benzamide pour inhiber l'activité d'abl1, d'abl2 et de bcr-abl2
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CA2752265A1 (fr) 2009-02-17 2010-08-26 Boehringer Ingelheim International Gmbh Derives pyrimido-[5,4-d]-pyrimidine pour l'inhibition des tyrosine-kinases
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Also Published As

Publication number Publication date
CL2011000691A1 (es) 2011-07-29
IL211744A0 (en) 2011-06-30
JP5603869B2 (ja) 2014-10-08
TW201018670A (en) 2010-05-16
WO2010034838A2 (fr) 2010-04-01
US8778929B2 (en) 2014-07-15
CN102227421A (zh) 2011-10-26
JP2012504114A (ja) 2012-02-16
PE20110294A1 (es) 2011-05-26
CA2738448A1 (fr) 2010-04-01
MX2011003292A (es) 2011-04-21
EP2350052B1 (fr) 2014-08-13
CO6351739A2 (es) 2011-12-20
AU2009295855A1 (en) 2010-04-01
EA201100564A1 (ru) 2011-12-30
WO2010034838A3 (fr) 2010-11-18
ECSP11010930A (es) 2011-04-29
UY32146A (es) 2010-04-30
BRPI0920608A2 (pt) 2019-09-24
KR20110063574A (ko) 2011-06-10
EP2350052A2 (fr) 2011-08-03
AR073700A1 (es) 2010-11-24
US20110312939A1 (en) 2011-12-22

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