CL2011000691A1 - Compuestos derivados de nicotinamida sustituida; composicion farmaceutica que los comprende; uso para el tratamiento y/o prevencion de cancer, infecciones, enfermedades inflamatorias y autoinmunitarias. - Google Patents
Compuestos derivados de nicotinamida sustituida; composicion farmaceutica que los comprende; uso para el tratamiento y/o prevencion de cancer, infecciones, enfermedades inflamatorias y autoinmunitarias.Info
- Publication number
- CL2011000691A1 CL2011000691A1 CL2011000691A CL2011000691A CL2011000691A1 CL 2011000691 A1 CL2011000691 A1 CL 2011000691A1 CL 2011000691 A CL2011000691 A CL 2011000691A CL 2011000691 A CL2011000691 A CL 2011000691A CL 2011000691 A1 CL2011000691 A1 CL 2011000691A1
- Authority
- CL
- Chile
- Prior art keywords
- infections
- inflammatory
- cancer
- prevention
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Abstract
Compuestos derivados de nicotinamida sustituida; composición farmacéutica que los comprende; uso para el tratamiento y/o prevención de cáncer, infecciones, enfermedades inflamatorias y autoinmunitarias.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08165437 | 2008-09-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2011000691A1 true CL2011000691A1 (es) | 2011-07-29 |
Family
ID=40019293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2011000691A CL2011000691A1 (es) | 2008-09-29 | 2011-03-29 | Compuestos derivados de nicotinamida sustituida; composicion farmaceutica que los comprende; uso para el tratamiento y/o prevencion de cancer, infecciones, enfermedades inflamatorias y autoinmunitarias. |
Country Status (20)
Country | Link |
---|---|
US (1) | US8778929B2 (es) |
EP (1) | EP2350052B1 (es) |
JP (1) | JP5603869B2 (es) |
KR (1) | KR20110063574A (es) |
CN (1) | CN102227421A (es) |
AR (1) | AR073700A1 (es) |
AU (1) | AU2009295855A1 (es) |
BR (1) | BRPI0920608A2 (es) |
CA (1) | CA2738448A1 (es) |
CL (1) | CL2011000691A1 (es) |
CO (1) | CO6351739A2 (es) |
EA (1) | EA201100564A1 (es) |
EC (1) | ECSP11010930A (es) |
IL (1) | IL211744A0 (es) |
MA (1) | MA32656B1 (es) |
MX (1) | MX2011003292A (es) |
PE (1) | PE20110294A1 (es) |
TW (1) | TW201018670A (es) |
UY (1) | UY32146A (es) |
WO (1) | WO2010034838A2 (es) |
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PE20090837A1 (es) | 2007-07-02 | 2009-07-24 | Boehringer Ingelheim Int | Nuevos compuestos quimicos |
TW201014860A (en) | 2008-09-08 | 2010-04-16 | Boehringer Ingelheim Int | New chemical compounds |
TW201018670A (en) | 2008-09-29 | 2010-05-16 | Boehringer Ingelheim Int | New chemical compounds |
CA2752265A1 (en) | 2009-02-17 | 2010-08-26 | Boehringer Ingelheim International Gmbh | Pyrimido [5,4-d] pyrimidine derivatives for the inhibition of tyrosine kinases |
JP2011057661A (ja) | 2009-08-14 | 2011-03-24 | Bayer Cropscience Ag | 殺虫性カルボキサミド類 |
JO3002B1 (ar) | 2009-08-28 | 2016-09-05 | Irm Llc | مركبات و تركيبات كمثبطات كيناز بروتين |
EP2552907B1 (en) * | 2010-03-26 | 2014-10-22 | Boehringer Ingelheim International GmbH | Pyridyltriazoles |
US9290507B2 (en) | 2010-03-26 | 2016-03-22 | Boehringer Ingelheim International Gmbh | B-RAF kinase inhibitors |
US8710055B2 (en) | 2010-12-21 | 2014-04-29 | Boehringer Ingelheim International Gmbh | Triazolylphenyl sulfonamides as serine/threonine kinase inhibitors |
US8889684B2 (en) | 2011-02-02 | 2014-11-18 | Boehringer Ingelheim International Gmbh | Azaindolylphenyl sulfonamides as serine/threonine kinase inhibitors |
EP2755652B1 (en) * | 2011-09-16 | 2021-06-02 | Novartis AG | N-substituted heterocyclyl carboxamides |
JP6150813B2 (ja) | 2011-11-11 | 2017-06-21 | ノバルティス アーゲー | 増殖性疾患の治療方法 |
CN105708819B (zh) | 2011-11-23 | 2020-12-29 | 诺华股份有限公司 | 医药制剂 |
CA2769821C (en) | 2012-02-28 | 2020-08-11 | Michael Hatzinikolas | Self-releasing structural assembly |
CN104334529B (zh) | 2012-05-15 | 2017-03-15 | 诺华股份有限公司 | 用于抑制abl1、abl2和bcr‑abl1的活性的化合物和组合物 |
JP6078640B2 (ja) | 2012-05-15 | 2017-02-08 | ノバルティス アーゲー | Abl1、abl2およびbcr−abl1の活性を阻害するためのベンズアミド誘導体 |
AU2013261130A1 (en) | 2012-05-15 | 2014-10-23 | Novartis Ag | Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1 |
AU2013261127B2 (en) | 2012-05-15 | 2015-03-12 | Novartis Ag | Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1 |
JP6936796B2 (ja) | 2015-07-06 | 2021-09-22 | ロダン・セラピューティクス,インコーポレーテッド | ヒストンデアセチラーゼのヘテロハロ阻害剤 |
US10421756B2 (en) | 2015-07-06 | 2019-09-24 | Rodin Therapeutics, Inc. | Heterobicyclic N-aminophenyl-amides as inhibitors of histone deacetylase |
US10717731B2 (en) * | 2015-10-23 | 2020-07-21 | Mitsubishi Tanabe Pharma Corporation | Nitrogen-containing aromatic heterocyclic compound |
CN106316864A (zh) * | 2016-08-22 | 2017-01-11 | 苏州天马精细化学品股份有限公司 | 4‑甲基‑3‑三氟甲基苯胺的制备方法 |
ES2909086T3 (es) | 2017-01-11 | 2022-05-05 | Alkermes Inc | Inhibidores bicíclicos de histona desacetilasa |
MA49839B1 (fr) | 2017-08-07 | 2022-05-31 | Alkermes Inc | Inhibiteurs bicycliques de la histone déacétylase |
CN108707147A (zh) * | 2018-06-20 | 2018-10-26 | 桑文军 | 一种新型微管蛋白抑制剂及其在抗肿瘤药物中的应用 |
WO2020036949A1 (en) * | 2018-08-14 | 2020-02-20 | Biogen Ma Inc. | Ask1 inhibiting agents |
CA3121202A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
WO2022188792A1 (zh) * | 2021-03-12 | 2022-09-15 | 四川科伦博泰生物医药股份有限公司 | 具有蛋白激酶抑制活性的杂环化合物、包含其的药物组合物及其制备方法和用途 |
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TW201014860A (en) | 2008-09-08 | 2010-04-16 | Boehringer Ingelheim Int | New chemical compounds |
TW201018670A (en) | 2008-09-29 | 2010-05-16 | Boehringer Ingelheim Int | New chemical compounds |
CA2752265A1 (en) | 2009-02-17 | 2010-08-26 | Boehringer Ingelheim International Gmbh | Pyrimido [5,4-d] pyrimidine derivatives for the inhibition of tyrosine kinases |
EP2552907B1 (en) | 2010-03-26 | 2014-10-22 | Boehringer Ingelheim International GmbH | Pyridyltriazoles |
US9290507B2 (en) | 2010-03-26 | 2016-03-22 | Boehringer Ingelheim International Gmbh | B-RAF kinase inhibitors |
US8710055B2 (en) | 2010-12-21 | 2014-04-29 | Boehringer Ingelheim International Gmbh | Triazolylphenyl sulfonamides as serine/threonine kinase inhibitors |
US20130023531A1 (en) | 2011-01-27 | 2013-01-24 | Boehringer Ingelheim International Gmbh | Pyrimido[5,4-d]pyrimidylamino phenyl sulfonamides as serine/threonine kinase inhibitors |
US8889684B2 (en) | 2011-02-02 | 2014-11-18 | Boehringer Ingelheim International Gmbh | Azaindolylphenyl sulfonamides as serine/threonine kinase inhibitors |
-
2009
- 2009-09-28 TW TW098132738A patent/TW201018670A/zh unknown
- 2009-09-28 CN CN2009801476559A patent/CN102227421A/zh active Pending
- 2009-09-28 MX MX2011003292A patent/MX2011003292A/es not_active Application Discontinuation
- 2009-09-28 WO PCT/EP2009/062551 patent/WO2010034838A2/en active Application Filing
- 2009-09-28 CA CA2738448A patent/CA2738448A1/en not_active Abandoned
- 2009-09-28 PE PE2011000796A patent/PE20110294A1/es not_active Application Discontinuation
- 2009-09-28 EA EA201100564A patent/EA201100564A1/ru unknown
- 2009-09-28 BR BRPI0920608A patent/BRPI0920608A2/pt not_active IP Right Cessation
- 2009-09-28 AR ARP090103730A patent/AR073700A1/es unknown
- 2009-09-28 UY UY0001032146A patent/UY32146A/es not_active Application Discontinuation
- 2009-09-28 AU AU2009295855A patent/AU2009295855A1/en not_active Abandoned
- 2009-09-28 US US13/121,241 patent/US8778929B2/en active Active
- 2009-09-28 EP EP09783505.2A patent/EP2350052B1/en active Active
- 2009-09-28 KR KR1020117009679A patent/KR20110063574A/ko not_active Application Discontinuation
- 2009-09-28 JP JP2011528358A patent/JP5603869B2/ja active Active
-
2011
- 2011-03-15 IL IL211744A patent/IL211744A0/en unknown
- 2011-03-25 CO CO11036947A patent/CO6351739A2/es not_active Application Discontinuation
- 2011-03-28 MA MA33729A patent/MA32656B1/fr unknown
- 2011-03-29 EC EC2011010930A patent/ECSP11010930A/es unknown
- 2011-03-29 CL CL2011000691A patent/CL2011000691A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2012504114A (ja) | 2012-02-16 |
US20110312939A1 (en) | 2011-12-22 |
MX2011003292A (es) | 2011-04-21 |
MA32656B1 (fr) | 2011-09-01 |
KR20110063574A (ko) | 2011-06-10 |
EA201100564A1 (ru) | 2011-12-30 |
IL211744A0 (en) | 2011-06-30 |
EP2350052A2 (en) | 2011-08-03 |
WO2010034838A3 (en) | 2010-11-18 |
CN102227421A (zh) | 2011-10-26 |
ECSP11010930A (es) | 2011-04-29 |
UY32146A (es) | 2010-04-30 |
PE20110294A1 (es) | 2011-05-26 |
WO2010034838A2 (en) | 2010-04-01 |
CA2738448A1 (en) | 2010-04-01 |
AU2009295855A1 (en) | 2010-04-01 |
EP2350052B1 (en) | 2014-08-13 |
BRPI0920608A2 (pt) | 2019-09-24 |
CO6351739A2 (es) | 2011-12-20 |
TW201018670A (en) | 2010-05-16 |
JP5603869B2 (ja) | 2014-10-08 |
AR073700A1 (es) | 2010-11-24 |
US8778929B2 (en) | 2014-07-15 |
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