MA30807B1 - Compositions pharmaceutiques. - Google Patents

Compositions pharmaceutiques.

Info

Publication number
MA30807B1
MA30807B1 MA31809A MA31809A MA30807B1 MA 30807 B1 MA30807 B1 MA 30807B1 MA 31809 A MA31809 A MA 31809A MA 31809 A MA31809 A MA 31809A MA 30807 B1 MA30807 B1 MA 30807B1
Authority
MA
Morocco
Prior art keywords
pharmaceutical compositions
pellets
salt
produced
pharmaceutically acceptable
Prior art date
Application number
MA31809A
Other languages
English (en)
Inventor
Nathalie Bruneau
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37684496&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA30807(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA30807B1 publication Critical patent/MA30807B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA PRÉSENTE INVENTION CONCERNE UNE COMPOSITION PHARMACEUTIQUE, EN PARTICULIER DES CAPSULES, COMPRENANT DES GRANULÉS CONTENANT DU NILOTINIB OU UN SEL DE CELUI-CI, AINSI QU'AU MOINS UN EXCIPIENT PHARMACEUTIQUEMENT ACCEPTABLE. CES GRANULÉS PEUVENT ÊTRE PRODUITS PAR UN PROCÉDÉ DE GRANULATION PAR VOIE HUMIDE.
MA31809A 2006-09-27 2009-04-22 Compositions pharmaceutiques. MA30807B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121371A EP1923053A1 (fr) 2006-09-27 2006-09-27 Composition pharmaceutique comprenant de la nilotinib ou son sel

Publications (1)

Publication Number Publication Date
MA30807B1 true MA30807B1 (fr) 2009-10-01

Family

ID=37684496

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31809A MA30807B1 (fr) 2006-09-27 2009-04-22 Compositions pharmaceutiques.

Country Status (35)

Country Link
US (2) US8293756B2 (fr)
EP (4) EP1923053A1 (fr)
JP (2) JP5567340B2 (fr)
KR (2) KR20090076931A (fr)
CN (2) CN101516344A (fr)
AR (1) AR062980A1 (fr)
AU (1) AU2007301977B2 (fr)
BR (1) BRPI0719438B1 (fr)
CA (1) CA2662571C (fr)
CL (1) CL2007002766A1 (fr)
CO (1) CO6160288A2 (fr)
CY (2) CY1117021T1 (fr)
DK (2) DK2068839T3 (fr)
ES (3) ES2556625T5 (fr)
FI (2) FI3984528T3 (fr)
HK (1) HK1133193A1 (fr)
HR (2) HRP20230753T3 (fr)
HU (2) HUE063083T2 (fr)
IL (1) IL197496A (fr)
JO (1) JO3757B1 (fr)
LT (1) LT3984528T (fr)
MA (1) MA30807B1 (fr)
MX (1) MX2009003184A (fr)
MY (1) MY148237A (fr)
NO (2) NO347404B1 (fr)
NZ (1) NZ575317A (fr)
PE (2) PE20120626A1 (fr)
PL (2) PL3984528T3 (fr)
PT (2) PT3984528T (fr)
RU (1) RU2469707C2 (fr)
SI (2) SI2068839T2 (fr)
TN (1) TN2009000093A1 (fr)
TW (3) TWI428333B (fr)
WO (1) WO2008037716A2 (fr)
ZA (1) ZA200901511B (fr)

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EP1923053A1 (fr) 2006-09-27 2008-05-21 Novartis AG Composition pharmaceutique comprenant de la nilotinib ou son sel
CA2775400A1 (fr) 2009-09-28 2011-03-31 Medizinische Universitat Wien Nouvelle utilisation des inhibiteurs de pdgf-beta
US20120202836A1 (en) 2009-10-23 2012-08-09 Tomasz Szczudlo Method of treating proliferative disorders and other pathological conditions mediated by bcr-abl, c-kit, ddr1, ddr2 or pdgf-r kinase activity
JO3634B1 (ar) 2009-11-17 2020-08-27 Novartis Ag طريقة لعلاج اضطرابات تكاثرية وحالات مرضية أخرى متوسطة بنشاط كيناز bcr-abl، c-kit، ddr1، ddr2، أو pdgf-r
IN2011CH01887A (fr) * 2011-06-02 2012-12-14
AR086913A1 (es) * 2011-06-14 2014-01-29 Novartis Ag 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida amorfa, forma de dosificacion que la contiene y metodo para prepararlas
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WO2013063003A1 (fr) 2011-10-28 2013-05-02 Novartis Ag Méthode de traitement des tumeurs stromales gastro-intestinales
AU2012328979B2 (en) 2011-10-28 2016-04-21 Novartis Ag Method of treating gastrointestinal stromal tumors
KR20140093230A (ko) * 2011-11-14 2014-07-25 노파르티스 아게 즉시 방출 4-메틸-3-[[4-(3-피리디닐)-2-피리미디닐]아미노]-n-[5-(4-메틸-1h-이미다졸-1-일)-3-(트리플루오로메틸)페닐] 벤즈아미드 제제
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WO2017158625A1 (fr) * 2016-03-17 2017-09-21 Sun Pharmaceutical Industries Ltd. Composition pharmaceutique du nilotinib
CN107582531B (zh) * 2016-07-06 2020-12-29 四川科伦药物研究院有限公司 一种利伐沙班固体制剂及其制备方法
CN107320460B (zh) * 2017-08-04 2020-11-03 北京化工大学 一种尼罗替尼口服纳米制剂及其制备方法
CN107441094B (zh) * 2017-08-08 2020-05-22 南方医科大学 尼罗替尼作为治疗登革病毒感染的药物及其制药用途
CZ2017821A3 (cs) 2017-12-20 2019-07-03 Zentiva, K.S. Léková forma obsahující krystalický nilotinib
CN113292537B (zh) 2018-06-15 2024-04-05 汉达癌症医药责任有限公司 激酶抑制剂的盐类及其组合物
WO2021155254A1 (fr) 2020-01-31 2021-08-05 Nanocopoeia, Llc Microparticules de nilotinib amorphe et leurs utilisations
WO2021222739A1 (fr) 2020-04-30 2021-11-04 Nanocopoeia, Llc Comprimé à désintégration orale comprenant une dispersion solide amorphe de nilotinib
JP7489849B2 (ja) 2020-07-20 2024-05-24 日本化薬株式会社 ニロチニブ錠剤
AU2022292092A1 (en) 2021-06-19 2024-02-01 Helm Ag Granulate composition comprising nilotinib
WO2023285981A1 (fr) * 2021-07-15 2023-01-19 Torrent Pharmaceuticals Limited Composition pharmaceutique liquide stable de nilotinib
EP4122452A1 (fr) 2021-07-23 2023-01-25 KRKA, d.d., Novo mesto Composition pharmaceutique comprenant du nilotinib et son procédé de fabrication
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Also Published As

Publication number Publication date
SI2068839T2 (sl) 2023-01-31
HK1133193A1 (en) 2010-03-19
NO346639B1 (no) 2022-11-07
HRP20151383T1 (hr) 2016-01-15
HUE028204T2 (en) 2016-12-28
JO3757B1 (ar) 2021-01-31
SI3984528T1 (sl) 2023-09-29
CO6160288A2 (es) 2010-05-20
BRPI0719438B1 (pt) 2022-04-19
IL197496A (en) 2016-04-21
LT3984528T (lt) 2023-08-10
FI3984528T3 (fi) 2023-07-27
US20130023549A1 (en) 2013-01-24
ES2951547T3 (es) 2023-10-23
CY1117021T1 (el) 2017-04-05
HUE063083T2 (hu) 2023-12-28
AR062980A1 (es) 2008-12-17
IL197496A0 (en) 2009-12-24
MX2009003184A (es) 2009-04-03
CY1126116T1 (el) 2023-11-15
US8501760B2 (en) 2013-08-06
BRPI0719438A2 (pt) 2013-12-10
DK3984528T3 (da) 2023-07-31
PL2068839T5 (pl) 2023-01-30
TW200821298A (en) 2008-05-16
TW201418244A (zh) 2014-05-16
WO2008037716A2 (fr) 2008-04-03
PT2068839E (pt) 2015-12-30
KR101598747B1 (ko) 2016-03-02
TW201418245A (zh) 2014-05-16
US20100087463A1 (en) 2010-04-08
RU2009115782A (ru) 2010-11-10
CA2662571C (fr) 2016-09-27
HRP20230753T3 (hr) 2023-10-27
EP1923053A1 (fr) 2008-05-21
AU2007301977A1 (en) 2008-04-03
PT3984528T (pt) 2023-08-07
NO20220946A1 (no) 2009-04-24
CN104306350A (zh) 2015-01-28
JP2010504942A (ja) 2010-02-18
NZ575317A (en) 2011-12-22
NO347404B1 (no) 2023-10-16
TN2009000093A1 (en) 2010-08-19
ES2957912T3 (es) 2024-01-29
EP3984528B1 (fr) 2023-07-05
EP2068839B2 (fr) 2022-10-12
WO2008037716A3 (fr) 2008-07-17
KR20140121903A (ko) 2014-10-16
PL3984528T3 (pl) 2023-08-28
CL2007002766A1 (es) 2008-08-08
EP3009128B1 (fr) 2023-07-05
EP2068839A2 (fr) 2009-06-17
EP3984528A1 (fr) 2022-04-20
ES2556625T5 (es) 2023-03-02
MY148237A (en) 2013-03-29
PL2068839T3 (pl) 2016-06-30
CN101516344A (zh) 2009-08-26
TWI540128B (zh) 2016-07-01
ZA200901511B (en) 2010-02-24
CA2662571A1 (fr) 2008-04-03
HRP20151383T4 (hr) 2023-03-03
ES2556625T3 (es) 2016-01-19
SI2068839T1 (sl) 2016-02-29
NO20091501L (no) 2009-04-24
DK2068839T3 (da) 2016-01-11
JP2014065715A (ja) 2014-04-17
TWI428333B (zh) 2014-03-01
RU2469707C2 (ru) 2012-12-20
US8293756B2 (en) 2012-10-23
PE20081379A1 (es) 2008-11-27
PE20120626A1 (es) 2012-06-07
KR20090076931A (ko) 2009-07-13
JP5567340B2 (ja) 2014-08-06
AU2007301977B2 (en) 2011-09-08
EP2068839B1 (fr) 2015-09-23
EP3009128A1 (fr) 2016-04-20
FI2068839T4 (fi) 2023-01-31

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