MX2009003184A - Composiciones farmaceuticas que comprenden nilotinib o su sal. - Google Patents

Composiciones farmaceuticas que comprenden nilotinib o su sal.

Info

Publication number
MX2009003184A
MX2009003184A MX2009003184A MX2009003184A MX2009003184A MX 2009003184 A MX2009003184 A MX 2009003184A MX 2009003184 A MX2009003184 A MX 2009003184A MX 2009003184 A MX2009003184 A MX 2009003184A MX 2009003184 A MX2009003184 A MX 2009003184A
Authority
MX
Mexico
Prior art keywords
salt
nilotinib
pharmaceutical compositions
granules
produced
Prior art date
Application number
MX2009003184A
Other languages
English (en)
Inventor
Nathalie Bruneau
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37684496&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009003184(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009003184A publication Critical patent/MX2009003184A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Una composición farmacéutica, en especial cápsulas, la cual comprende gránulos que contienen nilotinib o una sal del mismo, con cuando menos un excipiente farmacéuticamente aceptable. Los gránulos se pueden producir mediante un proceso de granulación húmeda.
MX2009003184A 2006-09-27 2007-09-25 Composiciones farmaceuticas que comprenden nilotinib o su sal. MX2009003184A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06121371A EP1923053A1 (en) 2006-09-27 2006-09-27 Pharmaceutical compositions comprising nilotinib or its salt
PCT/EP2007/060165 WO2008037716A2 (en) 2006-09-27 2007-09-25 Pharmaceutical compositions comprising nilotinib or its salt

Publications (1)

Publication Number Publication Date
MX2009003184A true MX2009003184A (es) 2009-04-03

Family

ID=37684496

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003184A MX2009003184A (es) 2006-09-27 2007-09-25 Composiciones farmaceuticas que comprenden nilotinib o su sal.

Country Status (35)

Country Link
US (2) US8293756B2 (es)
EP (4) EP1923053A1 (es)
JP (2) JP5567340B2 (es)
KR (2) KR20090076931A (es)
CN (2) CN104306350A (es)
AR (1) AR062980A1 (es)
AU (1) AU2007301977B2 (es)
BR (1) BRPI0719438B1 (es)
CA (1) CA2662571C (es)
CL (1) CL2007002766A1 (es)
CO (1) CO6160288A2 (es)
CY (2) CY1117021T1 (es)
DK (2) DK2068839T3 (es)
ES (3) ES2957912T3 (es)
FI (2) FI3984528T3 (es)
HK (1) HK1133193A1 (es)
HR (2) HRP20230753T3 (es)
HU (2) HUE028204T2 (es)
IL (1) IL197496A (es)
JO (1) JO3757B1 (es)
LT (1) LT3984528T (es)
MA (1) MA30807B1 (es)
MX (1) MX2009003184A (es)
MY (1) MY148237A (es)
NO (2) NO346639B1 (es)
NZ (1) NZ575317A (es)
PE (2) PE20081379A1 (es)
PL (2) PL2068839T5 (es)
PT (2) PT3984528T (es)
RU (1) RU2469707C2 (es)
SI (2) SI2068839T2 (es)
TN (1) TN2009000093A1 (es)
TW (3) TWI428333B (es)
WO (1) WO2008037716A2 (es)
ZA (1) ZA200901511B (es)

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* Cited by examiner, † Cited by third party
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AU2010299756A1 (en) 2009-09-28 2012-04-19 Medizinische Universitat Wien PDGFRbeta inhibitors for use in the treatment of T-cell lymphoma
EP2490690A1 (en) * 2009-10-23 2012-08-29 Novartis AG Method of treating proliferative disorders and other pathological conditions mediated by bcr-abl, c-kit, ddr1, ddr2 or pdgf-r kinase activity
JO3634B1 (ar) 2009-11-17 2020-08-27 Novartis Ag طريقة لعلاج اضطرابات تكاثرية وحالات مرضية أخرى متوسطة بنشاط كيناز bcr-abl، c-kit، ddr1، ddr2، أو pdgf-r
WO2012164578A1 (en) * 2011-06-02 2012-12-06 Hetero Research Foundation Compositions and methods for preparing immediate release formulations of nilotinib
AR086913A1 (es) * 2011-06-14 2014-01-29 Novartis Ag 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida amorfa, forma de dosificacion que la contiene y metodo para prepararlas
CN102321073A (zh) * 2011-08-12 2012-01-18 西安交通大学 一种尼罗替尼的制备方法
RU2014120792A (ru) 2011-10-28 2015-12-10 Новартис Аг Способ лечения стромальных опухолей желудочно-кишечного тракта
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JP6275645B2 (ja) * 2011-11-14 2018-02-07 ノバルティス アーゲー ４−メチル−３−［［４−（３−ピリジニル）−２−ピリミジニル］アミノ］−ｎ−［５−（４−メチル−１ｈ−イミダゾール−１−イル）−３−（トリフルオロメチル）フェニル］ベンズアミドの即放性製剤
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LT3189045T (lt) 2014-08-11 2022-04-11 Sun Pharmaceutical Industries Limited Naujos nilotinibo druskos ir jų polimorfai
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CN107582531B (zh) * 2016-07-06 2020-12-29 四川科伦药物研究院有限公司 一种利伐沙班固体制剂及其制备方法
CN107320460B (zh) * 2017-08-04 2020-11-03 北京化工大学 一种尼罗替尼口服纳米制剂及其制备方法
CN107441094B (zh) * 2017-08-08 2020-05-22 南方医科大学 尼罗替尼作为治疗登革病毒感染的药物及其制药用途
CZ2017821A3 (cs) 2017-12-20 2019-07-03 Zentiva, K.S. Léková forma obsahující krystalický nilotinib
CN116808044A (zh) 2018-06-15 2023-09-29 汉达癌症医药责任有限公司 激酶抑制剂的盐类及其组合物
AU2021212258A1 (en) 2020-01-31 2022-09-29 Nanocopoeia, Llc Amorphous nilotinib microparticles and uses thereof
IL297776A (en) 2020-04-30 2022-12-01 Nanocopoeia Llc Orally disintegrating tablets containing an amorphous solid dispersion of nalotinib
JP7489849B2 (ja) 2020-07-20 2024-05-24 日本化薬株式会社 ニロチニブ錠剤
EP4355306A1 (en) 2021-06-19 2024-04-24 Helm AG Granulate composition comprising nilotinib
WO2023285981A1 (en) * 2021-07-15 2023-01-19 Torrent Pharmaceuticals Limited Stable pharmaceutical liquid composition of nilotinib
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WO2024142002A1 (en) 2022-12-29 2024-07-04 Renata Pharmaceuticals (Ireland) Limited Pharmaceutical suspension of nilotinib

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Also Published As

Publication number Publication date
US8501760B2 (en) 2013-08-06
PE20120626A1 (es) 2012-06-07
FI2068839T4 (fi) 2023-01-31
CA2662571A1 (en) 2008-04-03
NZ575317A (en) 2011-12-22
NO20091501L (no) 2009-04-24
AU2007301977B2 (en) 2011-09-08
NO346639B1 (no) 2022-11-07
TW201418244A (zh) 2014-05-16
PL2068839T3 (pl) 2016-06-30
HUE028204T2 (en) 2016-12-28
KR20090076931A (ko) 2009-07-13
RU2469707C2 (ru) 2012-12-20
JP2010504942A (ja) 2010-02-18
KR101598747B1 (ko) 2016-03-02
NO20220946A1 (no) 2009-04-24
PL3984528T3 (pl) 2023-08-28
EP3984528A1 (en) 2022-04-20
SI3984528T1 (sl) 2023-09-29
KR20140121903A (ko) 2014-10-16
CN101516344A (zh) 2009-08-26
IL197496A (en) 2016-04-21
CO6160288A2 (es) 2010-05-20
DK2068839T3 (da) 2016-01-11
SI2068839T2 (sl) 2023-01-31
US20100087463A1 (en) 2010-04-08
MA30807B1 (fr) 2009-10-01
PT3984528T (pt) 2023-08-07
EP2068839B2 (en) 2022-10-12
IL197496A0 (en) 2009-12-24
CY1117021T1 (el) 2017-04-05
EP3984528B1 (en) 2023-07-05
EP3009128A1 (en) 2016-04-20
EP2068839A2 (en) 2009-06-17
TW201418245A (zh) 2014-05-16
FI3984528T3 (fi) 2023-07-27
HRP20230753T3 (hr) 2023-10-27
LT3984528T (lt) 2023-08-10
EP1923053A1 (en) 2008-05-21
BRPI0719438B1 (pt) 2022-04-19
AR062980A1 (es) 2008-12-17
HRP20151383T1 (hr) 2016-01-15
CA2662571C (en) 2016-09-27
PL2068839T5 (pl) 2023-01-30
NO347404B1 (no) 2023-10-16
CN104306350A (zh) 2015-01-28
ES2556625T5 (es) 2023-03-02
TW200821298A (en) 2008-05-16
JO3757B1 (ar) 2021-01-31
HUE063083T2 (hu) 2023-12-28
CL2007002766A1 (es) 2008-08-08
RU2009115782A (ru) 2010-11-10
ZA200901511B (en) 2010-02-24
ES2556625T3 (es) 2016-01-19
HK1133193A1 (en) 2010-03-19
EP3009128B1 (en) 2023-07-05
WO2008037716A2 (en) 2008-04-03
BRPI0719438A2 (pt) 2013-12-10
MY148237A (en) 2013-03-29
US20130023549A1 (en) 2013-01-24
WO2008037716A3 (en) 2008-07-17
PE20081379A1 (es) 2008-11-27
TN2009000093A1 (en) 2010-08-19
HRP20151383T4 (hr) 2023-03-03
EP2068839B1 (en) 2015-09-23
ES2957912T3 (es) 2024-01-29
JP2014065715A (ja) 2014-04-17
CY1126116T1 (el) 2023-11-15
US8293756B2 (en) 2012-10-23
SI2068839T1 (sl) 2016-02-29
ES2951547T3 (es) 2023-10-23
JP5567340B2 (ja) 2014-08-06
AU2007301977A1 (en) 2008-04-03
TWI540128B (zh) 2016-07-01
DK3984528T3 (da) 2023-07-31
PT2068839E (pt) 2015-12-30
TWI428333B (zh) 2014-03-01

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