PL2068839T3 - Kompozycje farmaceutyczne zawierające nilotynib lub jego sól - Google Patents

Kompozycje farmaceutyczne zawierające nilotynib lub jego sól

Info

Publication number
PL2068839T3
PL2068839T3 PL07820560T PL07820560T PL2068839T3 PL 2068839 T3 PL2068839 T3 PL 2068839T3 PL 07820560 T PL07820560 T PL 07820560T PL 07820560 T PL07820560 T PL 07820560T PL 2068839 T3 PL2068839 T3 PL 2068839T3
Authority
PL
Poland
Prior art keywords
nilotinib
salt
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
PL07820560T
Other languages
English (en)
Other versions
PL2068839T5 (pl
Inventor
Nathalie Bruneau
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37684496&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2068839(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2068839T3 publication Critical patent/PL2068839T3/pl
Publication of PL2068839T5 publication Critical patent/PL2068839T5/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL07820560.6T 2006-09-27 2007-09-25 Kompozycje farmaceutyczne zawierające nilotynib lub jego sól PL2068839T5 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06121371A EP1923053A1 (en) 2006-09-27 2006-09-27 Pharmaceutical compositions comprising nilotinib or its salt
PCT/EP2007/060165 WO2008037716A2 (en) 2006-09-27 2007-09-25 Pharmaceutical compositions comprising nilotinib or its salt
EP07820560.6A EP2068839B2 (en) 2006-09-27 2007-09-25 Pharmaceutical compositions comprising nilotinib or its salt

Publications (2)

Publication Number Publication Date
PL2068839T3 true PL2068839T3 (pl) 2016-06-30
PL2068839T5 PL2068839T5 (pl) 2023-01-30

Family

ID=37684496

Family Applications (2)

Application Number Title Priority Date Filing Date
PL21194622.3T PL3984528T3 (pl) 2006-09-27 2007-09-25 Kompozycje farmaceutyczne zawierające nilotynib
PL07820560.6T PL2068839T5 (pl) 2006-09-27 2007-09-25 Kompozycje farmaceutyczne zawierające nilotynib lub jego sól

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL21194622.3T PL3984528T3 (pl) 2006-09-27 2007-09-25 Kompozycje farmaceutyczne zawierające nilotynib

Country Status (35)

Country Link
US (2) US8293756B2 (pl)
EP (4) EP1923053A1 (pl)
JP (2) JP5567340B2 (pl)
KR (2) KR20090076931A (pl)
CN (2) CN101516344A (pl)
AR (1) AR062980A1 (pl)
AU (1) AU2007301977B2 (pl)
BR (1) BRPI0719438B1 (pl)
CA (1) CA2662571C (pl)
CL (1) CL2007002766A1 (pl)
CO (1) CO6160288A2 (pl)
CY (2) CY1117021T1 (pl)
DK (2) DK3984528T3 (pl)
ES (3) ES2957912T3 (pl)
FI (2) FI2068839T4 (pl)
HK (1) HK1133193A1 (pl)
HR (2) HRP20230753T3 (pl)
HU (2) HUE028204T2 (pl)
IL (1) IL197496A (pl)
JO (1) JO3757B1 (pl)
LT (1) LT3984528T (pl)
MA (1) MA30807B1 (pl)
MX (1) MX2009003184A (pl)
MY (1) MY148237A (pl)
NO (2) NO347404B1 (pl)
NZ (1) NZ575317A (pl)
PE (2) PE20081379A1 (pl)
PL (2) PL3984528T3 (pl)
PT (2) PT3984528T (pl)
RU (1) RU2469707C2 (pl)
SI (2) SI3984528T1 (pl)
TN (1) TN2009000093A1 (pl)
TW (3) TW201418245A (pl)
WO (1) WO2008037716A2 (pl)
ZA (1) ZA200901511B (pl)

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CA2775400A1 (en) 2009-09-28 2011-03-31 Medizinische Universitat Wien New use of pdgfrbeta inhibitors
EP2490690A1 (en) * 2009-10-23 2012-08-29 Novartis AG Method of treating proliferative disorders and other pathological conditions mediated by bcr-abl, c-kit, ddr1, ddr2 or pdgf-r kinase activity
JO3634B1 (ar) 2009-11-17 2020-08-27 Novartis Ag طريقة لعلاج اضطرابات تكاثرية وحالات مرضية أخرى متوسطة بنشاط كيناز bcr-abl، c-kit، ddr1، ddr2، أو pdgf-r
WO2012164578A1 (en) * 2011-06-02 2012-12-06 Hetero Research Foundation Compositions and methods for preparing immediate release formulations of nilotinib
AR086913A1 (es) * 2011-06-14 2014-01-29 Novartis Ag 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida amorfa, forma de dosificacion que la contiene y metodo para prepararlas
CN102321073A (zh) * 2011-08-12 2012-01-18 西安交通大学 一种尼罗替尼的制备方法
WO2013063003A1 (en) 2011-10-28 2013-05-02 Novartis Ag Method of treating gastrointestinal stromal tumors
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US9636340B2 (en) 2013-11-12 2017-05-02 Ayyappan K. Rajasekaran Kinase inhibitors
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US10045987B2 (en) * 2014-08-28 2018-08-14 Codexis, Inc. Imidazoyl anilide derivatives and methods of use
EP3429589B1 (en) * 2016-03-17 2022-12-14 Sun Pharmaceutical Industries Ltd Pharmaceutical composition of nilotinib
CN107582531B (zh) * 2016-07-06 2020-12-29 四川科伦药物研究院有限公司 一种利伐沙班固体制剂及其制备方法
CN107320460B (zh) * 2017-08-04 2020-11-03 北京化工大学 一种尼罗替尼口服纳米制剂及其制备方法
CN107441094B (zh) * 2017-08-08 2020-05-22 南方医科大学 尼罗替尼作为治疗登革病毒感染的药物及其制药用途
CZ2017821A3 (cs) 2017-12-20 2019-07-03 Zentiva, K.S. Léková forma obsahující krystalický nilotinib
TWI815137B (zh) 2018-06-15 2023-09-11 漢達生技醫藥股份有限公司 尼洛替尼十二烷基硫酸鹽之結晶
AU2021212258A1 (en) 2020-01-31 2022-09-29 Nanocopoeia, Llc Amorphous nilotinib microparticles and uses thereof
EP4142699A1 (en) 2020-04-30 2023-03-08 Nanocopoeia LLC Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib
JP7489849B2 (ja) 2020-07-20 2024-05-24 日本化薬株式会社 ニロチニブ錠剤
CA3224750A1 (en) 2021-06-19 2022-12-22 Helm Ag Granulate composition comprising nilotinib
WO2023285981A1 (en) * 2021-07-15 2023-01-19 Torrent Pharmaceuticals Limited Stable pharmaceutical liquid composition of nilotinib
EP4122452A1 (en) 2021-07-23 2023-01-25 KRKA, d.d., Novo mesto Pharmaceutical composition comprising nilotinib and method of manufacturing the same
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CN101516339B (zh) * 2006-08-16 2012-06-13 诺瓦提斯公司 制备高度结晶的治疗化合物的固体分散体的方法
EP1923053A1 (en) * 2006-09-27 2008-05-21 Novartis AG Pharmaceutical compositions comprising nilotinib or its salt

Also Published As

Publication number Publication date
IL197496A (en) 2016-04-21
HRP20151383T4 (hr) 2023-03-03
US20130023549A1 (en) 2013-01-24
EP3984528A1 (en) 2022-04-20
SI3984528T1 (sl) 2023-09-29
DK2068839T3 (da) 2016-01-11
BRPI0719438B1 (pt) 2022-04-19
CY1126116T1 (el) 2023-11-15
MY148237A (en) 2013-03-29
BRPI0719438A2 (pt) 2013-12-10
ES2957912T3 (es) 2024-01-29
EP3009128A1 (en) 2016-04-20
JO3757B1 (ar) 2021-01-31
ES2556625T5 (es) 2023-03-02
EP2068839B2 (en) 2022-10-12
JP2010504942A (ja) 2010-02-18
AU2007301977B2 (en) 2011-09-08
SI2068839T2 (sl) 2023-01-31
CA2662571A1 (en) 2008-04-03
LT3984528T (lt) 2023-08-10
RU2469707C2 (ru) 2012-12-20
FI2068839T4 (fi) 2023-01-31
HUE063083T2 (hu) 2023-12-28
KR20140121903A (ko) 2014-10-16
CA2662571C (en) 2016-09-27
NO20220946A1 (no) 2009-04-24
AU2007301977A1 (en) 2008-04-03
CO6160288A2 (es) 2010-05-20
KR101598747B1 (ko) 2016-03-02
PL3984528T3 (pl) 2023-08-28
EP2068839A2 (en) 2009-06-17
RU2009115782A (ru) 2010-11-10
MA30807B1 (fr) 2009-10-01
CN104306350A (zh) 2015-01-28
ES2556625T3 (es) 2016-01-19
TW200821298A (en) 2008-05-16
HRP20151383T1 (hr) 2016-01-15
ZA200901511B (en) 2010-02-24
US20100087463A1 (en) 2010-04-08
NO20091501L (no) 2009-04-24
PE20081379A1 (es) 2008-11-27
JP5567340B2 (ja) 2014-08-06
HUE028204T2 (en) 2016-12-28
CL2007002766A1 (es) 2008-08-08
TWI540128B (zh) 2016-07-01
IL197496A0 (en) 2009-12-24
US8501760B2 (en) 2013-08-06
KR20090076931A (ko) 2009-07-13
ES2951547T3 (es) 2023-10-23
TWI428333B (zh) 2014-03-01
EP2068839B1 (en) 2015-09-23
TW201418245A (zh) 2014-05-16
MX2009003184A (es) 2009-04-03
PT2068839E (pt) 2015-12-30
EP1923053A1 (en) 2008-05-21
WO2008037716A3 (en) 2008-07-17
NO346639B1 (no) 2022-11-07
PT3984528T (pt) 2023-08-07
EP3984528B1 (en) 2023-07-05
JP2014065715A (ja) 2014-04-17
NZ575317A (en) 2011-12-22
AR062980A1 (es) 2008-12-17
CY1117021T1 (el) 2017-04-05
DK3984528T3 (da) 2023-07-31
HK1133193A1 (en) 2010-03-19
EP3009128B1 (en) 2023-07-05
TN2009000093A1 (en) 2010-08-19
US8293756B2 (en) 2012-10-23
HRP20230753T3 (hr) 2023-10-27
PE20120626A1 (es) 2012-06-07
NO347404B1 (no) 2023-10-16
SI2068839T1 (sl) 2016-02-29
TW201418244A (zh) 2014-05-16
WO2008037716A2 (en) 2008-04-03
FI3984528T3 (fi) 2023-07-27
CN101516344A (zh) 2009-08-26
PL2068839T5 (pl) 2023-01-30

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